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Grape Seed Proanthocyanidin Suppression Of Breast Cell Carcinogenesis Induced By Chronic Exposure To Combined 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone And Benzo[A]Pyrene, X Song, Kusum Rathore, N Siriwardhana, D Lin, Hwa-Chain Wang 2009 University of Tennessee - Knoxville

Grape Seed Proanthocyanidin Suppression Of Breast Cell Carcinogenesis Induced By Chronic Exposure To Combined 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone And Benzo[A]Pyrene, X Song, Kusum Rathore, N Siriwardhana, D Lin, Hwa-Chain Wang

Kusum Rathore MS, PhD, College of Veterinary Medicine

Breast cancer is the most common type of cancer among women in northern America and northern Europe; dietary prevention is a cost-efficient strategy to reduce the risk of this disease. To identify dietary components for the prevention of human breast cancer associated with long-term exposure to environmental carcinogens, we studied the activity of grape seed proanthocyanidin extract (GSPE) in suppression of cellular carcinogenesis induced by repeated exposures to low doses of environmental carcinogens. We used combined carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and benzo[a]pyrene (B[a]P), at picomolar concentrations, to repeatedly treat noncancerous, human breast epithelial ...


An Overview Of Physical Growth And Maturation, Andrew Hills, Nuala Byrne 2009 Selected Works

An Overview Of Physical Growth And Maturation, Andrew Hills, Nuala Byrne

Nuala Byrne

No abstract provided.


Physical Inactivity, Appetite Regulation And Obesity, Neil King, Rachel Colley, Nuala Byrne, Andrew Hills 2009 Selected Works

Physical Inactivity, Appetite Regulation And Obesity, Neil King, Rachel Colley, Nuala Byrne, Andrew Hills

Nuala Byrne

No abstract provided.


A Review Of Autoimmune Diseases Associated With Cancer, Patricia Tai, Edward Yu, Kurian Joseph, Thomas Miale 2009 University of Saskatchewan

A Review Of Autoimmune Diseases Associated With Cancer, Patricia Tai, Edward Yu, Kurian Joseph, Thomas Miale

Edward Yu

The focus of this review is on the relationships between autoimmune diseases and cancer from two closely related perspectives: 1.Those autoimmune diseases which are often associated with malignancies. 2.Those prevalent cancers which may increase the risks of developing autoimmune disorders. The review concludes with a brief discussion of some selected innovative approaches to cancer immunotherapy.


The Antecedents And Outcomes Of Attachment And Sponsor Image Within Charity Sport Events, Kevin Filo, Daniel Funk, Danny O'Brien 2009 Bond University

The Antecedents And Outcomes Of Attachment And Sponsor Image Within Charity Sport Events, Kevin Filo, Daniel Funk, Danny O'Brien

Danny O'Brien

Sport events benefiting a charitable cause have emerged as meaningful experiences for participants. These charity sport events may allow event sponsors to shape perceptions of corporate image among event participants. Using the Psychological Continuum Model (PCM) as the theoretical framework, the factors that contribute to participants' perceptions of event sponsors are examined. The influence of this image of event sponsors on behavioral outcomes among participants is also investigated. A post-event questionnaire was administered to participants in a sport event (A^ = 672) to investigate the relationships among motives, sponsor image, event attachment, purchase intent, and future participation intent. Results reveal that ...


Finding Information By "Design": Search Strategies For Cardiothoracic And Vascular Anesthesia Literature, Denise Hersey, Viji Kurup 2009 Yale University

Finding Information By "Design": Search Strategies For Cardiothoracic And Vascular Anesthesia Literature, Denise Hersey, Viji Kurup

Denise Hersey

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Desired Outcomes Of An Undergraduate Education In Psychology From Departmental, Student, And Societal Perspectives, R. Landrum, Bernard Beins, Mukul Bhalla, Karen Brakke, Deborah Briihl, Rita Curl-Langager, Thomas Pusateri, Jaye Van Kirk 2009 Boise State University

Desired Outcomes Of An Undergraduate Education In Psychology From Departmental, Student, And Societal Perspectives, R. Landrum, Bernard Beins, Mukul Bhalla, Karen Brakke, Deborah Briihl, Rita Curl-Langager, Thomas Pusateri, Jaye Van Kirk

R. Eric Landrum

What are the desired outcomes of an undergraduate education in psychology? It is vital to identify the desired outcomes that benefit departments, students, and society, because the pursuit of these goals helps psychology educators achieve the best possible learning experience for their students. We purposely take a different approach to what might be expected of an outcomes chapter in a review of undergraduate psychology education. We address methods that departments and educational institutions use to assess the outcomes of psychology education from the standpoint of departmental performance and student achievement. We identify goals of the undergraduate experience held by psychology ...


Health Survey Instrument Development Through A Community-Based Participatory Research Approach:Health Promoting Lifestyle Profile (Hplp-Ii) And Brazilian Immigrants In Greater Boston, Mansoureh Tajik, Heloisa Galvão, Carlos Siqueira 2009 University of Massachusetts Boston

Health Survey Instrument Development Through A Community-Based Participatory Research Approach:Health Promoting Lifestyle Profile (Hplp-Ii) And Brazilian Immigrants In Greater Boston, Mansoureh Tajik, Heloisa Galvão, Carlos Siqueira

C. Eduardo Siqueira

Brazilians are among the fastest growing segment of immigrant populations in several states of the United States. Culturally appropriate and validated health survey instruments do not exist to adequately assess the health needs of this population. Through a community-based participatory research (CBPR) approach, a cross-cultural pilot project was conducted to develop and test a culturally-adapted Brazilian Portuguese-version of the health-promoting lifestyle profile II (HPLP-II) instrument with a convenience sample of 60 bilingual and bicultural Brazilian immigrants using a combined quasi experimental and focus group design. The project evaluated HPLP-II instrument's psychometric properties of equivalency, reliability, and score distribution in ...


Photovoice In The Workplace.Pdf, Marian Flum, Carlos Siqueira, Anthony DeCaro, Scott Redway 2009 Selected Works

Photovoice In The Workplace.Pdf, Marian Flum, Carlos Siqueira, Anthony Decaro, Scott Redway

C. Eduardo Siqueira

Background Photovoice, a photographic participatory action research methodology was
used in a workplace setting to assess hazards that were creating extremely high injury and
incidents rates for university custodians and to promote the conditions to eliminate or
reduce those hazards.
Methods University custodians participated in a Photovoice project to identify, categorize,
and prioritize occupational hazards and to discuss and propose solutions to these
problems. Results were presented to management and to all custodians for further
discussion. The effort was led by a worker-based union-sponsored participatory evaluation
team in partnership with a university researcher.
Results Visual depiction of hazardous tasks and ...


Early Intervention In Psychotic Disorders: Challenges And Relevance In The Indian Context, Matcheri Keshavan, Amresh Shrivastava, Bangalore Gangadhar 2009 Harvard University

Early Intervention In Psychotic Disorders: Challenges And Relevance In The Indian Context, Matcheri Keshavan, Amresh Shrivastava, Bangalore Gangadhar

Amresh Srivastava

Over the last two decades, there has been an increasing interest in the concept of early intervention (EI) in psychotic disorders, notably schizophrenia. Several lines of research underlie this emerging paradigm shift: (a) an increasingly well-established association between the duration of prolonged untreated illness and poor outcome; (b) evidence of progressive neurobiological changes in the early course of schizophrenia both in the pre-psychotic and psychotic phases, as evidenced by brain imaging studies in schizophrenia; and (c) emerging data, albeit preliminary, suggesting the efficacy and effectiveness of EI programs in improving the outcome in these patients. Mental health service systems across ...


Pkc Inhibition Increases Gap Junction Intercellular Communication And Cell Adhesion In Human Neuroblastoma, M. Morley, C. Jones, M. Sidhu, V. Gupta, S. Bernier, W. Rushlow, Daniel Belliveau 2009 The University of Western Ontario

Pkc Inhibition Increases Gap Junction Intercellular Communication And Cell Adhesion In Human Neuroblastoma, M. Morley, C. Jones, M. Sidhu, V. Gupta, S. Bernier, W. Rushlow, Daniel Belliveau

Daniel J. Belliveau

Abstract Gap junction intercellular communication and cell–cell adhesion are essential for maintaining a normal cellular phenotype, including the control of growth and proliferation. Loss of either cell–cell adhesion or communication is common in cancers, while restoration of function is associated with tumor suppression. Protein kinase C (PKC) isozymes regulate a broad spectrum of cellular functions including growth and proliferation, and their overexpression has been correlated with carcinogenesis. Consequently, PKC inhibitors are currently undergoing clinical trials as an anti-cancer agents although the precise cellular alterations induced by PKC inhibitors remain to be elucidated. In the current study, the effects ...


Weight-Gain In Psychiatric Treatment: Risks, Implications, And Strategies For Prevention And Management, Amresh Srivastava, Megan Johnston 2009 University of Western Ontario

Weight-Gain In Psychiatric Treatment: Risks, Implications, And Strategies For Prevention And Management, Amresh Srivastava, Megan Johnston

Amresh Srivastava

Weight-gain in psychiatric populations is a common clinical challenge. Many patients suffering from mental disorders, when exposed to psychotropic medications, gain significant weight with or without other side-effects. In addition to reducing the patients' willingness to comply with treatment, this weight-gain may create added psychological or physiological problems that need to be addressed. Thus, it is critical that clinicians take precautions to monitor and control weight-gain and take into account and treat all problems facing an individual. In this review, we examine some of the key issues surrounding weight-gain in individuals suffering from mental disorders for contemporary practitioners in community ...


Anuran Susceptibilities To Ranaviruses: Role Of Species Identity, Exposure Route, And A Novel Virus Isolate., J. Hoverman, Matthew Gray, Debra Miller 2009 University of Tennessee, Knoxville

Anuran Susceptibilities To Ranaviruses: Role Of Species Identity, Exposure Route, And A Novel Virus Isolate., J. Hoverman, Matthew Gray, Debra Miller

Debra L Miller

Ranaviruses are responsible for widespread amphibian die-offs, particularly with larval anurans. To understand the factors that may be contributing to the emergence of ranaviruses, we conducted 3 experiments that exposed 3 species of larval anurans to either endemic frog virus 3 (FV3) or an FV3-like isolate from a ranaculture facility. Our goals were to (1) determine the susceptibility of each species to each virus, (2) determine whether direct ingestion of virions or exposure to virions in a water bath were similarly lethal routes of transmission, and (3) quantify the effects of exposure duration on disease outcomes. We conducted our research ...


How To Professionalise Your Practice As A Health Professions Educator, Michelle McLean 2009 Bond University

How To Professionalise Your Practice As A Health Professions Educator, Michelle Mclean

Michelle McLean

No abstract provided.


Impaired Expression And Function Of Toll-Like Receptor 7 In Hepatitis C Virus Infection In Human Hepatoma Cells, Serena Chang, Karen Kodys, Gyongyi Szabo 2009 University of Massachusetts Medical School

Impaired Expression And Function Of Toll-Like Receptor 7 In Hepatitis C Virus Infection In Human Hepatoma Cells, Serena Chang, Karen Kodys, Gyongyi Szabo

Gyongyi Szabo

Hepatitis C virus (HCV) interferes with interferon (IFN)-mediated innate immune defenses. Toll-like receptor (TLR) 7 agonists robustly inhibit HCV infection. We hypothesize that HCV infection may interfere with the expression and/or function of TLR7, a sensor of single-stranded RNA. We identified reduced TLR7 RNA and protein levels in hepatoma cells expressing HCV (full-length, BB7-subgenomic, and JFH-1 clone) compared with control HCV-naive cells. The biological relevance of this finding was confirmed by the observation of decreased TLR7 RNA in livers of HCV-infected patients compared with controls. HCV clearance, by IFN-alpha treatment or restrictive culture conditions, restored the decreased TLR7 ...


Lessons Learned From Research In Prodromal Phase Of Schizophrenia, Amresh Shrivastava, Megan Johnston 2009 The University of Western Ontario

Lessons Learned From Research In Prodromal Phase Of Schizophrenia, Amresh Shrivastava, Megan Johnston

Amresh Srivastava

In the last ten years, a significant amount of research data has accumulated to identify and predict the vulnerability of individuals to develop psychosis. At a time when DSM-V academia is becoming active with field trials, researchers in prodromal psychosis research are arguing for inclusion of 'risk syndrome for psychosis,' which has generated an interesting debate. Studies indicate that approximately 80-85% of cases experience subsyndromal symptoms for a period lasting from several months to several years prior to the onset of the illness, including impaired perception, thought processes, subjective cognitive functions and mood. Also, much of the functional decline associated ...


Early Detection, Aggressive Therapy: Optimizing The Management Of Feline Mammary Masses, Fernanda Gimenez, Silke Hecht, Linden Craig, Alfred Legendre 2009 University of Tennessee - Knoxville

Early Detection, Aggressive Therapy: Optimizing The Management Of Feline Mammary Masses, Fernanda Gimenez, Silke Hecht, Linden Craig, Alfred Legendre

Linden E. Craig DVM, Ph.D., DACVP, College of Veterinary Medicine

No abstract provided.


Tear Volume, Turnover Rate, And Flow Rate In Ophthalmologically Normal Horses, Thomas Chen, Daniel Ward 2009 University of Tennessee - Knoxville

Tear Volume, Turnover Rate, And Flow Rate In Ophthalmologically Normal Horses, Thomas Chen, Daniel Ward

Daniel A. Ward

No abstract provided.


Injuries And Illnesses On Wa Beaches 2006-2010, David Reid 2009 Edith Cowan University

Injuries And Illnesses On Wa Beaches 2006-2010, David Reid

David N Reid

This study analysed the trends in reported incidents occurring on patrolled Western Australian beaches, and review what proportion of those injured were transported to hospital by ambulance; and studied underlying factors present at the time of the reported incidents. The study was presented at an oral presentation as well as a poster presentation.


Martha Rogers, Mary Gunther 2009 Selected Works

Martha Rogers, Mary Gunther

Mary Gunther, PhD, RN

No abstract provided.


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