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185,757 full-text articles. Page 6168 of 6710.

Results Of Re-Excision For Inadequate Margins Following Partial Mastectomy For Carcinoma Of The Breast, Aaron D. Bleznak MD, FACS, Christine W. Du MD, Samuel Steerman MD, Elizabeth Dellers MD 2011 Lehigh Valley Health Network

Results Of Re-Excision For Inadequate Margins Following Partial Mastectomy For Carcinoma Of The Breast, Aaron D. Bleznak Md, Facs, Christine W. Du Md, Samuel Steerman Md, Elizabeth Dellers Md

Department of Surgery

No abstract provided.


Value Analysis: Perioperative Link In The Supply Chain, Gwenda L. Petrohoy MSN, MEd, RN, CNOR, Aaron D. Bleznak MD, FACS, Susan Toomey CMRP 2011 Lehigh Valley Health Network

Value Analysis: Perioperative Link In The Supply Chain, Gwenda L. Petrohoy Msn, Med, Rn, Cnor, Aaron D. Bleznak Md, Facs, Susan Toomey Cmrp

Department of Surgery

No abstract provided.


Low Levels Of Hydrogen Peroxide Stimulate Corneal Epithelial Cell Adhesion, Migration, And Wound Healing, Qing Pan, Wen-Ya Qiu, Ya-Nan Huo, Yu-Feng Yao, Marjorie F. Lou 2011 Zhejiang University School of Medicine

Low Levels Of Hydrogen Peroxide Stimulate Corneal Epithelial Cell Adhesion, Migration, And Wound Healing, Qing Pan, Wen-Ya Qiu, Ya-Nan Huo, Yu-Feng Yao, Marjorie F. Lou

Papers in Veterinary and Biomedical Science

PURPOSE. Intracellular reactive oxygen species have been reported to associate with growth factor and integrin signalings in promoting cell adhesion in many cell types. This study is to explore if exogenous H2O2 at low levels can be beneficial to cell adhesion, migration, and wound healing.

METHODS. Primary rabbit corneal epithelial cells treated with 0–70 M H2O2 were tested for viability by MTT assay, adhesion by centrifugation assay, focal contacts of vinculin and F-actin by immunofluorescence, activated Src(pY416), EGF receptor (pY845), vinculin(pY1065), FAK(pY397), and FAK(pY576) by immunoblotting. Cell migration was examined with 0–50 M H2O2 ...


Understanding The Context Of Balanced Scorecard Implementation: A Hospital-Based Case Study In Pakistan., F Rabbani, Sabrina NH Lalji, Farhat Abbas, SM Wasim Jafri, Junaid A. Razzak, Naheed Nabi, Firdous Jahan, Agha Ajmal, Max Petzold, Mats Brommels, Goran Tomson 2011 Aga Khan University

Understanding The Context Of Balanced Scorecard Implementation: A Hospital-Based Case Study In Pakistan., F Rabbani, Sabrina Nh Lalji, Farhat Abbas, Sm Wasim Jafri, Junaid A. Razzak, Naheed Nabi, Firdous Jahan, Agha Ajmal, Max Petzold, Mats Brommels, Goran Tomson

Section of Urology

Background: As a response to a changing operating environment, healthcare administrators are implementing modern management tools in their organizations. The balanced scorecard (BSC) is considered a viable tool in high-income countries to improve hospital performance. The BSC has not been applied to hospital settings in low-income countries nor has the context for implementation been examined. This study explored contextual perspectives in relation to BSC implementation in a Pakistani hospital. Methods: Four clinical units of this hospital were involved in the BSC implementation based on their willingness to participate. Implementation included sensitization of units towards the BSC, developing specialty specific BSCs ...


Harmonic Scalpel Versus Electrocautery Tonsillectomy: A Comparative Study In Adult Patients, Naeem Sultan Ali, Mubasher Ikram, Shabbir Akhtar, Iqbal Moghira, Ahmad Nawaz, Asif Arain 2011 Aga Khan University

Harmonic Scalpel Versus Electrocautery Tonsillectomy: A Comparative Study In Adult Patients, Naeem Sultan Ali, Mubasher Ikram, Shabbir Akhtar, Iqbal Moghira, Ahmad Nawaz, Asif Arain

Section of Otolaryngology, Head & Neck Surgery

OBJECTIVE: To compare harmonic scalpel (HS) tonsillectomy with electrocautery (EC) tonsillectomy in terms of operating time, intra-operative blood loss, post-operative pain and secondary haemorrhage.METHODS: Sixty adult patients subjected to tonsillectomy only, were evaluated in this prospective study. The patients were stratified into 2 groups (30 each) based on the dissecting instrument used (HS vs. EC) at Aga Khan University Hospital Karachi Pakistan from June, 2006 to August, 2008.RESULTS: The mean operative time was less in electrocautery group (EC 3.57 +/- 0.85 minutes Vs HS 4.20 +/- 1.37 minutes; p


The Use Of Non-Steroidal Anti-Inflammatory Drugs (Nsaids) In Treating Delayed Onset Muscle Soreness (Doms), Tiffany Windju 2011 California Polytechnic State University, San Luis Obispo

The Use Of Non-Steroidal Anti-Inflammatory Drugs (Nsaids) In Treating Delayed Onset Muscle Soreness (Doms), Tiffany Windju

Kinesiology and Public Health

No abstract provided.


Crystal Structure Of A Charge Engineered Human Lysozyme Having Enhanced Bactericidal Activity, Avinash Gill, Thomas C. Scanlon, Daniel C. Osipovitch, Dean R. Madden, Karl E. Griswold 2011 Dartmouth College

Crystal Structure Of A Charge Engineered Human Lysozyme Having Enhanced Bactericidal Activity, Avinash Gill, Thomas C. Scanlon, Daniel C. Osipovitch, Dean R. Madden, Karl E. Griswold

Open Dartmouth: Faculty Open Access Scholarship

Human lysozyme is a key component of the innate immune system, and recombinant forms of the enzyme represent promising leads in the search for therapeutic agents able to treat drug-resistant infections. The wild type protein, however, fails to participate effectively in clearance of certain infections due to inherent functional limitations. For example, wild type lysozymes are subject to electrostatic sequestration and inactivation by anionic biopolymers in the infected airway. A charge engineered variant of human lysozyme has recently been shown to possess improved antibacterial activity in the presence of disease associated inhibitory molecules. Here, the 2.04 A ̊ crystal structure ...


Kidney Injury Molecule-1 (Kim-1) As An Early Detection Tool For Acute Kidney Injury And Other Renal Diseases, John Fontanilla, MD, Won K. Han, M.D 2011 Thomas Jefferson University

Kidney Injury Molecule-1 (Kim-1) As An Early Detection Tool For Acute Kidney Injury And Other Renal Diseases, John Fontanilla, Md, Won K. Han, M.D

Department of Medicine Faculty Papers

Introduction: Although serum creatinine is the standard metric tool for the detection of renal injury, its lack of sensitivity has made the early diagnosis of acute kidney injury (AKI) very difficult. In fact, the absence of sensitive AKI biomarkers has impaired progress in the nephrology field and had a detrimental effect on the design and outcome of AKI clinical trials. Recently, several proteins have shown potential in the early detection of acute and chronic kidney injuries.

Areas covered: This review discusses the current status of kidney injury molecule-1 (KIM-1) as a potential diagnostic tool in patients with various acute and ...


Year In Review, Scott A. Waldman, Andre Terzic 2011 Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University

Year In Review, Scott A. Waldman, Andre Terzic

Department of Pharmacology and Experimental Therapeutics Faculty Papers

If examination of journal performance is a surrogate for the vitality of a discipline, the continued ascension of Clinical Pharmacology and Therapeutics (CPT) bodes well for the evolution and practice of human therapeutics in this decade. CPT has excelled as the authoritative, cross-disciplinary journal in experimental and clinical medicine devoted to publishing advances in the nature, action, efficacy and evaluation of therapeutics in humans. Building on a foundation that established the core tenets, and a framework providing the structural integrity for the field, CPT was conceived by visionary precedent editors and editorial teams who were themselves leaders of this discipline ...


The Pulmonologist's Role In Caring For Pregnant Women With Regard To The Reproductive Risks Of Diagnostic Radiological Studies Or Radiation Therapy., Robert Brent 2011 Thomas Jefferson University

The Pulmonologist's Role In Caring For Pregnant Women With Regard To The Reproductive Risks Of Diagnostic Radiological Studies Or Radiation Therapy., Robert Brent

Department of Pediatrics Faculty Papers

Radiography of the chest, head, neck, teeth, or extremity exposes the embryo or ovary to insignificant exposures of radiation except when radionuclides are utilized. In some instances, there is no exposure at all. Pulmonologists are fortunate with regard to the specific studies they request to provide clinical care because most of the diagnostic tests do not directly expose the uterus (embryo) or ovary. This article discusses radiation risks and their evaluation and pregnancy-related issues in diagnostic radiological studies.


Urological Involvement In Renal Transplantation., Daniel D Sackett, Pooja Singh, Costas D Lallas 2011 Thomas Jefferson University Hospital

Urological Involvement In Renal Transplantation., Daniel D Sackett, Pooja Singh, Costas D Lallas

Department of Urology Faculty Papers

Historically, urologists were the primary surgeons in renal transplantation. Specialization and increased complexity of the field of transplantation, coupled with a de-emphasis of vascular surgical training in urology, has created a situation where many renal transplants are carried out by surgeons with a general surgery background. Because of its genitourinary nature, however, urological input in renal transplantation is still vital. For living donors, a urologist should be involved to help evaluate and prepare certain patients for eventual donation. This could involve both medical and surgical intervention. Additionally, urologists who carry out living donor nephrectomy maintain a sense of ownership in ...


A Warm Welcome Goes A Long Way., Jody Shigo RN, CMSRN, Eileen Fruchtl MSN, RN, CCRN, CMSRN, Kai Bortz BSN, RN, CMSRN 2011 Lehigh Valley Health Network

A Warm Welcome Goes A Long Way., Jody Shigo Rn, Cmsrn, Eileen Fruchtl Msn, Rn, Ccrn, Cmsrn, Kai Bortz Bsn, Rn, Cmsrn

Patient Care Services / Nursing

No abstract provided.


Diagnosis Of Coronary Stenosis With Ct Angiography Comparison Of Automated Computer Diagnosis With Expert Readings., Ethan J Halpern, David J Halpern 2011 Thomas Jefferson University

Diagnosis Of Coronary Stenosis With Ct Angiography Comparison Of Automated Computer Diagnosis With Expert Readings., Ethan J Halpern, David J Halpern

Department of Radiology Faculty Papers

RATIONALE AND OBJECTIVES: To compare computer-generated interpretation of coronary computed tomography angiography (cCTA) by commercially available COR Analyzer software with expert human interpretation.

MATERIALS AND METHODS: This retrospective Health Insurance Portability and Accountability Act‑compliant study was approved by the institutional review board. Among 225 consecutive cCTA examinations, 207 were of adequate quality for automated evaluation. COR Analyzer interpretation was compared to human expert interpretation for detection of stenosis defined as ≥50% vessel diameter reduction in the left main, left anterior descending (LAD), circumflex (LCX), right coronary artery (RCA), or a branch vessel (diagonal, ramus, obtuse marginal, or posterior descending ...


Expression Of Aldehyde Dehydrogenase In Dysplastic Lesions Arising From Inflammatory Bowel Disease, Adam D. Toll, Bruce M. Boman, Juan P. Palazzo 2011 Thomas Jefferson University

Expression Of Aldehyde Dehydrogenase In Dysplastic Lesions Arising From Inflammatory Bowel Disease, Adam D. Toll, Bruce M. Boman, Juan P. Palazzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Conclusion: Our study demonstrates ALDH1 is significantly expressed in dysplatic lesions arising from IBD. ALDH1-expression in cancer stem cells suggest an important causative role in the progression to cancer in IBD. Although we found high sensitivity for dysplasia, the specificity was poor. In addition to neoplasia, ALDH1-expressing stem cells proliferate in response to chronic inflammation, accounting for the cases of inflammatory atypia with positive ALDHI1 expression.


On Old Olympic Towering Tops A Finn And German Viewed Some Hops., Kristen Gaumer RN, CNRN 2011 Lehigh Valley Health Network

On Old Olympic Towering Tops A Finn And German Viewed Some Hops., Kristen Gaumer Rn, Cnrn

Patient Care Services / Nursing

No abstract provided.


Driving For Results: Building A Strong Local Aann Chapter To Assure Relevance In Neuroscience Nursing, Holly Tavianini RN, BSN, MSHSA, CNRN, Jill Hinnershitz MSN, RN 2011 Lehigh Valley Health Network

Driving For Results: Building A Strong Local Aann Chapter To Assure Relevance In Neuroscience Nursing, Holly Tavianini Rn, Bsn, Mshsa, Cnrn, Jill Hinnershitz Msn, Rn

Patient Care Services / Nursing

No abstract provided.


Open To The Public: Meeting The Nursing Challenge Of A Diverse America, Bonnie Wasilowsky RN, BSPA-HCA, CNRN 2011 Lehigh Valley Health Network

Open To The Public: Meeting The Nursing Challenge Of A Diverse America, Bonnie Wasilowsky Rn, Bspa-Hca, Cnrn

Patient Care Services / Nursing

No abstract provided.


Posterior Reversible Encephalopathic Syndrome: Treating The Puzzling Syndrome Of Pres, Lorraine Valeriano BSN, RN, CNRN 2011 Lehigh Valley Health Network

Posterior Reversible Encephalopathic Syndrome: Treating The Puzzling Syndrome Of Pres, Lorraine Valeriano Bsn, Rn, Cnrn

Patient Care Services / Nursing

No abstract provided.


Family Presence During Resuscitation And/Or Invasive Procedures In The Emergency Department: One Size Does Not Fit All, Renae L. Dougal, Jill H. Anderson, Kathy Reavy, Christine C. Shirazi 2011 Saint Alphonsus Regional Medical Center

Family Presence During Resuscitation And/Or Invasive Procedures In The Emergency Department: One Size Does Not Fit All, Renae L. Dougal, Jill H. Anderson, Kathy Reavy, Christine C. Shirazi

Nursing Faculty Publications and Presentations

Family presence during resuscitation and/or invasive procedures is receiving more attention today as it speaks to the heart of patient and family-centered care. Family members are the most important support for their loved ones during vulnerable times such as a life-threatening event. Although family presence during resuscitation and/or invasive procedures is becoming a more accepted practice in hospital settings, only 5% of hospitals in the United States have unit policies guiding the practice of family presence in specialty settings.1-5 There is a need for family presence to be studied in non-academic hospitals and in other specialty settings ...


Providing Better Care At Lower Cost: Building Maine's Health Data Infrastructure To Support Financing And Delivery System Reform, Andrew F. Coburn PhD 2011 University of Southern Maine, Muskie School of Public Service, Maine Rural Health Research Center

Providing Better Care At Lower Cost: Building Maine's Health Data Infrastructure To Support Financing And Delivery System Reform, Andrew F. Coburn Phd

Health System Reform

Maine needs a robust and functional health data infrastructure to support efforts by health care providers and purchasers to improve quality, address Maine’s health care cost problems, and improve the health of individuals and populations through payment and delivery system reform. Although Maine has been a leader in building and using health data systems such as the hospital discharge data set and the all-payer claims database, new performance-based financing and delivery system arrangements are highlighting shortcomings in these systems and the need for a renewed vision of Maine’s future health data infrastructure.

The Health Data Workgroup was created ...


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