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Improving Health Outcomes For Children (Ihoc) In Maine Logic Model For Primary Care Practice Improvement, Cutler Institute of Health and Social Policy 2010 University of Southern Maine

Improving Health Outcomes For Children (Ihoc) In Maine Logic Model For Primary Care Practice Improvement, Cutler Institute Of Health And Social Policy

Population Health & Health Policy

Improving Health Outcomes for Children (IHOC) is a 5-year demonstration grant from the Centers for Medicare & Medicaid Services, and authorized by 401 (d) of the Children's Health Insurance Program Reauthorization Act of 2009 (CHIPRA).

IHOC works with doctors' offices, practices and other agencies who want to improve health care in Maine and Vermont to:

  • Collect and report on the use of evidenced-based child health quality measures
  • Expand the Health Information Technology to improve the flow of child health data
  • Promote a collaborative child health learning environment


Trastuzumab Sensitizes Ovarian Cancer Cells To Egfr-Targeted Therapeutics, Jason A. Wilken, Kristy T. Webster, Nita J. Maihle 2010 Yale University

Trastuzumab Sensitizes Ovarian Cancer Cells To Egfr-Targeted Therapeutics, Jason A. Wilken, Kristy T. Webster, Nita J. Maihle

Open Access Articles

BACKGROUND: Early studies have demonstrated comparable levels of HER2/ErbB2 expression in both breast and ovarian cancer. Trastuzumab (Herceptin), a therapeutic monoclonal antibody directed against HER2, is FDA-approved for the treatment of both early and late stage breast cancer. However, clinical studies of trastuzumab in epithelial ovarian cancer (EOC) patients have not met the same level of success. Surprisingly, however, no reports have examined either the basis for primary trastuzumab resistance in ovarian cancer or potential ways of salvaging trastuzumab as a potential ovarian cancer therapeutic.

METHODS: An in vitro model of primary trastuzumab-resistant ovarian cancer was created by long-term ...


Associations Of Race, Age, And Socioeconomic Status Among Women With Prediabetes: An Examination Of Nhanes Data 2005-2006 Regarding Prediabetes Risk, Rose T. Kattakayam 2010 Georgia State University

Associations Of Race, Age, And Socioeconomic Status Among Women With Prediabetes: An Examination Of Nhanes Data 2005-2006 Regarding Prediabetes Risk, Rose T. Kattakayam

Public Health Theses

Background: Prediabetes (PD) defined as having glucose values above normal but not high enough to be diagnosed as diabetes, is known to be a risk factor for type 2 diabetes and associated complications. Early prevention efforts can reverse the condition or delay the development of type 2 diabetes. This study examines the sociodemographic risk factors for PD in women. Methods: Using secondary data from National Health and Nutrition Examination Survey NHANES 2005-2006, chi-square analysis was done to find the prevalence of the disease among different categories of women with respect to age, ethnicity, and socioeconomic status. Univariate and multivariate analyses ...


The State Health Insurance Assistance Program (Ship), Carol O'Shaughnessy 2010 George Washington University

The State Health Insurance Assistance Program (Ship), Carol O'Shaughnessy

National Health Policy Forum

The State Health Insurance Assistance Program (SHIP), created by section 4360 of the Omnibus Budget Reconciliation Act (OBRA) of 1990 and administered by the Centers for Medicare & Medicaid Services (CMS), supports grants to states and jurisdictions to provide information, counseling, and assistance to Medicare beneficiaries and their families on Medicare and other health insurance questions. This publication describes the program and presents its funding history.


A View Of The Imd Pathway From The Rhim, Kamna Aggarwal 2010 University of Massachusetts Medical School

A View Of The Imd Pathway From The Rhim, Kamna Aggarwal

GSBS Dissertations and Theses

Innate immunity is the first line of defense against invading pathogens. It functions to eliminate pathogens and also to control infections. The innate immune response is also important for the development of pathogen-specific adaptive immune responses. As a result, the study of innate immune signaling pathways is crucial for understanding the interactions between host and pathogen. Unlike mammals, insects lack a classical adaptive immune response and rely mostly on innate immune responses.

Innate immune mechanisms have been widely studied in the fruit fly, Drosophila melanogaster. The genetic and molecular tools available in the Drosophila system make it an excellent model ...


Oral Health Checkup: Progress In Tough Fiscal Times?, Cynthia Shirk 2010 Himmelfarb Health Sciences Library, The George Washington University

Oral Health Checkup: Progress In Tough Fiscal Times?, Cynthia Shirk

National Health Policy Forum

Almost ten years after the surgeon general’s report designating dental disease as the “silent epidemic,” the nation continues to struggle with adequate access to and utilization of dental services. This is particularly true for low-income individuals, who experience more than twice the amount of untreated dental disease as their higher-income peers. This issue brief reviews sources of dental coverage for low-income children and adults and the challenges these programs face. It highlights some examples of state Medicaid initiatives to improve access and utilization for children and the progress of these initiatives. Finally, it examines the potential effects of the ...


Application Of A Leadership Approach To Address Suicide Among Gay, Lesbian And Bisexual Youth, Katherine Davis 2010 University of North Florida

Application Of A Leadership Approach To Address Suicide Among Gay, Lesbian And Bisexual Youth, Katherine Davis

Florida Public Health Review

Suicide, esepcially among youth, is a significant public health issue, ranking as the third leading cause of death among youth and young adults between the ages of 10 and 24. Suicide attempts and successful suicides are more frequent occurrences in the gay, lesbian,and bisexual (GLB) population. Despite this heightened risk, sexual orientation is omitted from important documents that detail suicide risk factors. Moreover, few schools have programs that address the unique needs of GLB youth that could create a more receptive or tolerant, and less threatening environment for them. In this paper, Kotter’s eight-stage framework for leadership is ...


Hiv Prevention And Education: Leadership And Implications For African-American Churches, Khaliah F. Fleming 2010 University of North Florida

Hiv Prevention And Education: Leadership And Implications For African-American Churches, Khaliah F. Fleming

Florida Public Health Review

This paper illustrates use of John Kotter’s eight-stage process for creating change through leadership its potential for aiding African-American churches in addressing rising HIV/AIDS rates. The focus is on churches due to their large influence on the African-American community. Knowing that there are multiple influences surrounding HIV/AIDS, it is useful to highlight how certain ideological and theological factors are contributing to the current state of African-American churches work to increase HIV/AIDS awareness, prevention, and education.


Leadership, Leadership Paradigms, And Leadership Training In 2010 And Beyond, Robert J. McDermott 2010 University of North Florida

Leadership, Leadership Paradigms, And Leadership Training In 2010 And Beyond, Robert J. Mcdermott

Florida Public Health Review

Since 2008, the Florida Public Health Review (FPHR) has published student essays that attempt to illustrate how the application of specific leadership paradigms might, in theory, be applied to address some nagging and ongoing problems in public health and related endeavors. The current volume of the FPHR continues that tradition. Other public health students, faculty, and practitioners from around the state are invited to contribute ideas that foster leadership skills and the development of dynamic leaders.


School Food Services And Childhood Obesity: Is There A Link?, Christine M. Spiker 2010 University of North Florida

School Food Services And Childhood Obesity: Is There A Link?, Christine M. Spiker

Florida Public Health Review

Childhood overweight and obesity have increased three-fold since 1980, and there is minimal evidence of any leveling off. Research has found that many school food programs are not sufficiently providing adequate nutrients and providing far too many calories and fat. Competitive foods are widely available in many schools which may possibly contribute to increased weight and body mass index (BMI) in students. This has put school food programs under scrutiny as a contributor to the childhood obesity crisis being faced. Schools can promote healthier eating by improving school meals, but most are forced to sell competitive foods to support their ...


Predictors Of Retention In Physical Therapy: Client-, Disease-, And Treatment-Related Factors, Marc A. Silva 2010 Marquette University

Predictors Of Retention In Physical Therapy: Client-, Disease-, And Treatment-Related Factors, Marc A. Silva

Counselor Education and Counseling Psychology Research Exchange Conference

OBJECTIVES: The objectives of the study are to (1) document the incidence of veterans who prematurely terminate physical therapy before medically indicated, and (2) identify reliable predictors of treatment retention and attrition. The potential benefit of this study is the identification of reliable variables that predict who is at risk for terminating physical therapy prematurely, which may lead to targeted interventions designed to increase treatment retention. RESEARCH DESIGN: This study will be a retrospective design involving a review of medical records of veterans receiving referral to physical therapy. METHODOLOGY: Multinomial logistic regression (MLR) will be used to examine the effects ...


Client-Treatment Matching In Substance Use Disorder Treatment: A Delphi Study, Noah Elijah Adrians 2010 Marquette University

Client-Treatment Matching In Substance Use Disorder Treatment: A Delphi Study, Noah Elijah Adrians

Counselor Education and Counseling Psychology Research Exchange Conference

Client-treatment matching (CTM) practices have been identified as important in enhancing substance use disorder (SUD) treatment outcomes while also minimizing the investment of time and resources necessary to achieve such outcomes. Despite strong positive effects associated with CTM, many questions remain regarding how CTM is implemented in treatment settings. This dissertation examines expert perspectives on how CTM practices are implemented in real world treatment settings, how to improve upon current practices, barriers to improvement, strategies for overcoming barriers, and consequensces of existing treatment system flaws. In this study, qualitative and quantitative data will be collected and analyzed through an iterative ...


Animal Models Of Focal Brain Ischemia, Kenneth M. Sicard, Marc Fisher 2010 University of Massachusetts Medical School

Animal Models Of Focal Brain Ischemia, Kenneth M. Sicard, Marc Fisher

Marc Fisher

Stroke is a leading cause of disability and death in many countries. Understanding the pathophysiology of ischemic injury and developing therapies is an important endeavor that requires much additional research. Animal stroke models provide an important mechanism for these activities. A large number of stroke models have been developed and are currently used in laboratories around the world. These models are overviewed as are approaches for measuring infarct size and functional outcome.


Latino Family Variables And Sexual Activity In Latino Adolescents, Brittany Nicole Barber 2010 Marquette University

Latino Family Variables And Sexual Activity In Latino Adolescents, Brittany Nicole Barber

Counselor Education and Counseling Psychology Research Exchange Conference

Researchers’ focused examination of Latino adolescents’ cultural values and sexual activity has yielded questions regarding the cultural- and gender-specific attitudes and practices of these youth (Deardorff, Tschann, & Flores, 2008). Cultural values include family-related variables such as different aspects of familism, parent-adolescent communication, and parental monitoring, which have been found to decrease adolescents’ engagement in other negative activities such as aggressive behavior, (Dishion & McMahon, 1998), substance use (Estrada, Rabow, & Watts, 1982), and delinquency (Clark & Shields, 1997). Research investigating these risk behaviors has often implicated Latino adolescents’ level of assimilation to White, mainstream society as a potential risk factor for higher engagement in negative behaviors. This dissertation study, therefore, will examine the relationship between five Latino family variables (i.e., attitudinal familism, behavioral familism, structural familism, parent-adolescent communication, and parental monitoring), assimilation to White society, and the sexual activity of Latino adolescents. A mixed-methods project has been designed to explore and test the relationships between these variables. Focus groups will be conducted with adolescents on the topics of family, gender, and sexual activity; data will be analyzed using Grounded Theory methodology (Strauss & Corbin, 1990). Latino youth will also complete surveys about these topics; the relationships among these variables will be explored statistically. For the purposes of the Research Exchange, a description of the current stage of the project at that time, a discussion of the anticipated results of the study, and an explanation of the contributions of this study to the Milwaukee and psychological communities will be included.


Language Outcome After Left Anterior Temporal Lobectomy In Patients With Discordant Functional Magnetic Resonance Imaging And Intracarotid Sodium Amobarbital Testing Results, Julie K. Janecek 2010 Marquette University

Language Outcome After Left Anterior Temporal Lobectomy In Patients With Discordant Functional Magnetic Resonance Imaging And Intracarotid Sodium Amobarbital Testing Results, Julie K. Janecek

Counselor Education and Counseling Psychology Research Exchange Conference

Language Outcome after Left Temporal Anterior Lobectomy in Patients with Discordant Functional Magnetic Resonance Imaging and Intracarotid Sodium Amobarbital Testing Results Rationale: Previous research has examined concordance rates between Wada and fMRI language lateralization indices (LIs) and has yielded variable results with limited post-surgical language outcome data. Therefore, additional evidence of the concurrent and predictive validity of fMRI LIs is needed. We will calculate Wada/fMRI LI concordance rates in the largest sample to date, investigate predictors of discordance and examine the ability of each procedure to predict language outcome in discordant cases. Methods: A consecutive series of 229 presurgical ...


Seeking Safety Group Proposal For Posttraumatic Stress Disorder And Co-Occurring Substance Use Disorder, Caryn P. Brakenridge 2010 Marquette University

Seeking Safety Group Proposal For Posttraumatic Stress Disorder And Co-Occurring Substance Use Disorder, Caryn P. Brakenridge

Counselor Education and Counseling Psychology Research Exchange Conference

Reports on rates of PTSD among women receiving treatment for substance use disorders (SUDs) ranges from 20% to as much as 59%. Research however has shown that fewer than half of women with SUDs will receive treatment that addresses their PTSD symptoms. Research over the past three decades has shown an increased interest in individuals diagnosed with posttraumatic stress disorder (PTSD) using group psychotherapy. However, group psychotherapy approaches for co-occurring PTSD and substance use disorders are not as well developed. This proposal suggests the creation of a psychotherapy group for women suffering from SUDs with co-occurring PTSD symptoms. The group ...


Multiple Oncogenic Viruses Identified In Ocular Surface Squamous Neoplasia In Hiv-1 Patients, Kenneth O. Simbiri, Masanao Murakami, Michael Feldman, Andrew P. Steenhoff, Oathokwa Nkomazana, Gregory P. Bisson, Erle S. Robertson 2010 University of Pennsylvania

Multiple Oncogenic Viruses Identified In Ocular Surface Squamous Neoplasia In Hiv-1 Patients, Kenneth O. Simbiri, Masanao Murakami, Michael Feldman, Andrew P. Steenhoff, Oathokwa Nkomazana, Gregory P. Bisson, Erle S. Robertson

Botswana-UPenn Scholarly Publications

Background

Ocular surface squamous neoplasia (OSSN) is a rare cancer that has increased in incidence with the HIV pandemic in Africa. The underlying cause of this cancer in HIV-infected patients from Botswana is not well defined.

Results

Tissues were obtained from 28 OSSN and 8 pterygia patients. The tissues analyzed from OSSN patients were 83% positive for EBV, 75% were HPV positive, 70% were KSHV positive, 75% were HSV-1/2 positive, and 61% were CMV positive by PCR. Tissues from pterygium patients were 88% positive for EBV, 75% were HPV positive, 50% were KSHV positive, and 60% were CMV positive ...


Nurses Of 2010: The Dichotomy Between Continuity Of Patient Care And Nursing Fatigue As Related To Shift Length, Christy Kurtz 2010 Southern Adventist Univeristy

Nurses Of 2010: The Dichotomy Between Continuity Of Patient Care And Nursing Fatigue As Related To Shift Length, Christy Kurtz

Senior Research Projects

Nursing shift lengths are widely debated, and the implications on both nurse and patient safety are quite large. This work seeks to present a current review of literature describing the current work schedules of nurses in comparison to the Institute of Medicine’s 2004 recommendations and both the positive and negative effects that these schedules have on nurses and their patients. Eleven studies from the past five years (2004-2009) are included, with particular emphasis on those studies that address the dispute between continuity of care and nursing fatigue. Results show that nurses are regularly working longer than is recommended, and ...


An Application Of Principal Component Analysis To The Clavicle And Clavicle Fixation Devices., Zubin J. Daruwalla, Patrick Courtis, Clare Fitzpatrick, David Fitzpatrick, Hannan Mullett 2010 Beaumont Hospital, Dublin

An Application Of Principal Component Analysis To The Clavicle And Clavicle Fixation Devices., Zubin J. Daruwalla, Patrick Courtis, Clare Fitzpatrick, David Fitzpatrick, Hannan Mullett

Trauma and Orthopaedic Surgery Articles

BACKGROUND: Principal component analysis (PCA) enables the building of statistical shape models of bones and joints. This has been used in conjunction with computer assisted surgery in the past. However, PCA of the clavicle has not been performed. Using PCA, we present a novel method that examines the major modes of size and three-dimensional shape variation in male and female clavicles and suggests a method of grouping the clavicle into size and shape categories.

MATERIALS AND METHODS: Twenty-one high-resolution computerized tomography scans of the clavicle were reconstructed and analyzed using a specifically developed statistical software package. After performing statistical shape ...


Neuropilin 1 Directly Interacts With Fer Kinase To Mediate Semaphorin3a-Induced Death Of Cortical Neurons, Susan X. Jiang, Shawn N. Whitehead, Amy Aylsworth, Bogdan Zurakowski, Kenneth Chan, Jianjun Li, Sheng T. Hou 2010 National Research Council

Neuropilin 1 Directly Interacts With Fer Kinase To Mediate Semaphorin3a-Induced Death Of Cortical Neurons, Susan X. Jiang, Shawn N. Whitehead, Amy Aylsworth, Bogdan Zurakowski, Kenneth Chan, Jianjun Li, Sheng T. Hou

Anatomy and Cell Biology Publications

Neuropilins (NRPs) are receptors for the major chemorepulsive axonal guidance cue semaphorins (Sema). The interaction of Sema3A/NRP1 during development leads to the collapse of growth cones. Here we show that Sema3A also induces death of cultured cortical neurons through NRP1. A specific NRP1 inhibitory peptide ameliorated Sema3A-evoked cortical axonal retraction and neuronal death. Moreover, Sema3A was also involved in cerebral ischemia-induced neuronal death. Expression levels of Sema3A and NRP1, but not NRP2, were significantly increased early during brain reperfusion following transient focal cerebral ischemia. NRP1 inhibitory peptide delivered to the ischemic brain was potently neuroprotective and prevented the loss ...


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