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Effects Of Genetic Background And Dietary Immunomodulators On Chicken Heterophil Function And Salmonella Resistance, Phongsakorn Chuammitri 2010 Iowa State University

Effects Of Genetic Background And Dietary Immunomodulators On Chicken Heterophil Function And Salmonella Resistance, Phongsakorn Chuammitri

Graduate Theses and Dissertations

Immune responses in poultry can be influenced by genetic background, nutrition, environment and management, or any combination of the above. Chicken heterophils are the first line of defense that can launch a series of intra- and extracellular antimicrobial mechanisms. Salmonella enterica serovar Enteritidis (SE) is a causative agent of a bacterial foodborne illness, commonly occurring after consumption of contaminated eggs and meat. In 2008, SE affected 3 out of 100,000 U.S. inhabitants on average and it is now receiving increased public awareness. The limited scope of current knowledge about basis for the difference in heterophil responses during and ...


Using Serum Cortisol To Distinguish Between Acute Stress And Pain Response Following Castration In Piglets, M. Hensch, L. L. Layman, L. A. Karriker, J. Coetzee, A. K. Johnson 2010 Iowa State University

Using Serum Cortisol To Distinguish Between Acute Stress And Pain Response Following Castration In Piglets, M. Hensch, L. L. Layman, L. A. Karriker, J. Coetzee, A. K. Johnson

Animal Science Conference Proceedings and Presentations

In the United States swine industry, castration is essentially universal and only a select number of male pigs are left intact as potential breeder boars. Pain and distress inflicted by castration is an animal well-being concern in livestock production. Castration in pigs has been shown to cause a stressful and painful response. The need for a robust, repeatable pysiological indicator of pain for use in the assessment of production practices designed to minimize these impacts has been recognized.


Colonization And Transmission Of Escherichia Coli O157:H7 In Swine, Nancy A. Cornick, Dianna M. Jordan, Sheridan L. Booher, Harley W. Moon 2010 Iowa State University

Colonization And Transmission Of Escherichia Coli O157:H7 In Swine, Nancy A. Cornick, Dianna M. Jordan, Sheridan L. Booher, Harley W. Moon

Veterinary Microbiology and Preventive Medicine Publications

Escherichia coli O157:H7 and other serogroups of Shiga toxin-producing E.coli (STEC) have emerged over the last several decades as a significant cause of food-borne illness in the United States. Approximately 5-10% of people clinically infected by these bacteria develop a systemic disease, hemolytic uremic syndrome, which has a fatality rate of approximately 5%. The Centers for Disease Control estimates that STEC cause some 110,000 illnesses and 90 deaths annually in the United States (Mead et al. 1999). In addition, the economic consequences of recalling large lots of food for public health reasons are significant. Cattle are considered ...


Descriptions Of Recent Incursions Of Exotic Animal Diseases, Anna R. Spickler, Jane Galyon, James A. Roth 2010 Iowa State University

Descriptions Of Recent Incursions Of Exotic Animal Diseases, Anna R. Spickler, Jane Galyon, James A. Roth

Veterinary Microbiology and Preventive Medicine Publications

Historically, livestock and poultry diseases have been introduced into new areas by the uncontrolled importation of animals and trade (including smuggling), through the movements of people and wildlife, and by vectors. Some diseases spread widely in the past. Rinderpest or “cattle plague,” for example, devastated farms as it was transported across continents by invading armies and their cattle, as well as by trade, the development of railways, and other factors. Other pathogens remained fairly localized for various reasons. Most of the parasites that cause African animal trypanosomiasis, for instance, must be transmitted by tsetse flies, and these insects have not ...


Three-Phase Model Harmonizes Estimates Of The Maximal Suppression Of Parathyroid Hormone By 25-Hydroxyvitamin D In Persons 65 Years Of Age And Older, Ramon A. Durazo-Arvizu, Bess Dawson-Hughes, Christopher T. Sempos, Elizabeth A. Yetley, Anne C. Looker, Guichan Cao, Susan S. Harris, Vicki L. Burt, Alicia L. Carriquiry, Mary Frances Picciano 2010 Loyola University Chicago

Three-Phase Model Harmonizes Estimates Of The Maximal Suppression Of Parathyroid Hormone By 25-Hydroxyvitamin D In Persons 65 Years Of Age And Older, Ramon A. Durazo-Arvizu, Bess Dawson-Hughes, Christopher T. Sempos, Elizabeth A. Yetley, Anne C. Looker, Guichan Cao, Susan S. Harris, Vicki L. Burt, Alicia L. Carriquiry, Mary Frances Picciano

Statistics Publications

The concentration or threshold of 25-hydroxyvitamin D [25(OH)D] needed to maximally suppress intact serum parathyroid hormone (iPTH) has been suggested as a measure of optimal vitamin D status. Depending upon the definition of maximal suppression of iPTH and the 2-phase regression approach used, 2 distinct clusters for a single 25(OH)D threshold have been reported: 16-20 ng/mL (40-50 nmol/L) and 30-32 ng/mL (75-80 nmol/L). To rationalize the apparently disparate published results, we compared thresholds from several regression models including a 3-phase one to estimate simultaneously 2 thresholds before and after adjusting for possible ...


Folic Acid Source, Usual Intake, And Folate And Vitamin B-12 Status In Us Adults: National Health And Nutrition Examination Survey (Nhanes) 2003–2006, Quanhe Yang, Mary E. Cogswell, Heather C. Hamner, Alicia L. Carriquiry, Christine M. Pfeiffer, Robert J. Berry 2010 Centers for Disease Control and Prevention

Folic Acid Source, Usual Intake, And Folate And Vitamin B-12 Status In Us Adults: National Health And Nutrition Examination Survey (Nhanes) 2003–2006, Quanhe Yang, Mary E. Cogswell, Heather C. Hamner, Alicia L. Carriquiry, Christine M. Pfeiffer, Robert J. Berry

Statistics Publications

Background: US adults have access to multiple sources of folic acid. The contribution of these sources to usual intakes above the tolerable upper intake level (UL) (1000 ug/d) and to folate and vitamin B-12 status is unknown. Objective: The objective was to estimate usual folic acid intake above the UL and adjusted serum and red blood cell folate, vitamin B-12, methylmalonic acid, and homocysteine concentrations among US adults by 3 major folic acid intake sources - enriched cereal-grain products (ECGP), ready-to-eat cereals (RTE), and supplements (SUP) - categorized into 4 mutually exclusive consumption groups. Design: We used data from the National ...


Molecular Staging Estimates Occult Tumor Burden In Colorectal Cancer, Alex Mejia, Stephanie Schulz, Terry Hyslop, David S. Weinberg, Scott A. Waldman 2010 Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University

Molecular Staging Estimates Occult Tumor Burden In Colorectal Cancer, Alex Mejia, Stephanie Schulz, Terry Hyslop, David S. Weinberg, Scott A. Waldman

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Tumor cells in regional lymph nodes are a key prognostic marker of survival and predictive marker of response to adjuvant chemotherapy in colorectal cancer. However, clinicopathologic techniques to detect lymph node metastases remain imperfect, and ~30% of patients with lymph nodes negative by histology (pN0) develop recurrent disease, reflecting occult metastases that escape detection. These observations underscore an unmet clinical need for accurate approaches to identify occult nodal metastases in colorectal cancer patients. GUCY2C is a receptor whose expression normally is restricted to intestinal epithelial cells, but is universally over-expressed by colorectal cancer cells. A prospective, multicenter, blinded clinical trial ...


The Impact Of Stakeholder Collaboration On Effectiveness Of Health Program Implementation In Ghana, Samuel Kwami Agbanu 2010 Walden University

The Impact Of Stakeholder Collaboration On Effectiveness Of Health Program Implementation In Ghana, Samuel Kwami Agbanu

Walden Dissertations and Doctoral Studies

Healthcare providers increasingly recognize the importance of collaboration among stakeholders in cost-effective healthcare delivery. While collaborative relationships offer great advantages, little research has addressed their relevance in an international development aid context, particularly in sub-Saharan Africa. The region is a major recipient of international development support, yet health indicators on HIV/AIDS, malaria, tuberculosis, and child and maternal mortality indicate the health of the region is among the weakest worldwide. This sequential mixed method, descriptive study of a USAID-funded community health program in Ghana examined the nature of collaboration among six stakeholders and impact of this collaboration on effectiveness of ...


The Effect Of Breastfeeding On The Bmi Of Hispanic Preschool Children, Linda M. Kilby 2010 Walden University

The Effect Of Breastfeeding On The Bmi Of Hispanic Preschool Children, Linda M. Kilby

Walden Dissertations and Doctoral Studies

The American Academy of Pediatrics and World Health Organization recommend exclusive breastfeeding for the first 4-6 months of life to reduce risk of obesity in pre-school children. Previous research has indicated a high rate of obesity among Hispanic children in the northeastern United States. There is also a gap in the literature regarding the effectiveness of exclusive breastfeeding in preventing obesity among preschool Hispanic children. Therefore, the purpose of this study was to determine if there was an association between exclusive breastfeeding and obesity among pre-school Hispanic children enrolled in the Special Supplemental Nutrition Education Program for Women, Infants and ...


National Survey On Equine Assisted Therapy: An Exploratory Study Of Current Practitioners And Programs, Patricia J. McConnell 2010 Walden University

National Survey On Equine Assisted Therapy: An Exploratory Study Of Current Practitioners And Programs, Patricia J. Mcconnell

Walden Dissertations and Doctoral Studies

Equine facilitated psychotherapy (EFP), a new field in psychology, is an alternative method of therapy that uses horses to facilitate therapeutic outcomes. There is minimal peer reviewed literature and few published studies examining efficacy. The conceptual lens of this study was grounded theory, as there is insufficient evidence of theoretical frame-works guiding equine assisted therapy. The purpose of this exploratory concurrent mixed methods study was to examine the theoretical foundation of practitioners; program make up; client populations; efficacy of program; and why the horse serves as the therapeutic catalyst of this model. A 43-item survey was sent to 800 programs ...


Manual Handling Workload And Musculoskeletal Discomfort Among Warehouse Personnel, Terrance N. Knox 2010 Walden University

Manual Handling Workload And Musculoskeletal Discomfort Among Warehouse Personnel, Terrance N. Knox

Walden Dissertations and Doctoral Studies

Work-related musculoskeletal disorders (WRMSD), specifically physical and muscular discomfort in the upper arm, lower arm, thigh, lower leg, wrist, shoulders, back, or neck, are among the most frequently reported workplace injuries in the United States. The dearth of knowledge about the types of workloads that may contribute to the development of WRMSD was the impetus of this research. The study aimed to identify antecedents of WRMSD among warehouse workers in order to reduce WRMSDs and increase productivity as expressed in a systems perspective on industrial health. The research questions examined the prevalence of specific WRMSDs, the relationship of high-risk tasks ...


Concurrent Partnerships As A Driver Of The Hiv Epidemic In Sub-Saharan Africa? The Evidence Is Limited, Mark N. Lurie, Samantha R. Rosenthal 2010 Brown University

Concurrent Partnerships As A Driver Of The Hiv Epidemic In Sub-Saharan Africa? The Evidence Is Limited, Mark N. Lurie, Samantha R. Rosenthal

Health & Wellness Department Faculty Publications and Research

No abstract provided.


A Survey Of Lymphoedema Practitioners Across The Us., Jane M. Armer, Electra D. Paskett, Mei R. Fu, Joseph L. Feldman, Robin Shook, Melanie K. Schneider, Bob R. Stewart, Janice N. Cormier 2010 University of Missouri

A Survey Of Lymphoedema Practitioners Across The Us., Jane M. Armer, Electra D. Paskett, Mei R. Fu, Joseph L. Feldman, Robin Shook, Melanie K. Schneider, Bob R. Stewart, Janice N. Cormier

Robin Shook

An online survey was developed by the American Lymphedema Framework Project (ALFP) executive and research committees to assess the current scope of practice in lymphoedema treatment in the US. The analysis included responses from 415 therapists from 46 states. Respondents typically had a background in physical or occupational therapy. Nearly all reported having completed a 135-hour training course on lymphoedema treatment and management. Treatment options most often reported were comprehensive decongestive therapy (CDT), exercise/movement, risk-reduction education, and skin care.


Type 2 Diabetes In Children: Estimates Of Epidemiology, Quality Of Care, Costs And Resource Utilization In A Medicaid Population, Vennela Thumula 2010 University of Mississippi

Type 2 Diabetes In Children: Estimates Of Epidemiology, Quality Of Care, Costs And Resource Utilization In A Medicaid Population, Vennela Thumula

Electronic Theses and Dissertations

Objective: the primary goal of this study was to assess the current state of diabetes, specifically type 2 diabetes in Mississippi Medicaid enrolled pediatric population. Background: Diabetes is the most prevalent pediatric chronic condition. Recent trends indicate that type 2 diabetes in children is increasing. Epidemiology estimates of type 2 diabetes in children and adolescents are limited. Quality of care and their health care utilization estimates are not available. Methods: 2002 - 2004 Mississippi Medicaid claims data were used for this study. A combination of ICD-9 codes (250.0x - 250.9x, where x=0 or 2) and/or oral hypoglycemic (OHG ...


Pharmacists' Rating Of Relevance Of Available Information In, Leonardo Roberto Torres 2010 University of Mississippi

Pharmacists' Rating Of Relevance Of Available Information In, Leonardo Roberto Torres

Electronic Theses and Dissertations

Pharmacists are tasked with making decisions regarding the validity of prescriptions. Some have proposed factors that should be considered when evaluating a prescription's validity. Yet, there is little known about the decision process that pharmacists employ at the time of dispensing and what information pharmacists deem relevant in that decision-making process. Using an online survey instrument, a sample of community pharmacists were divided into three groups and presented with a prescription scenario. They were asked to rate the relevance of information, which is proposed to be appropriate and inappropriate, available at the time of dispensing. They were asked to ...


Preparation And Characterization Of Lyophilized Cyclodextrin Complexes Of A Hemisuccinate Ester Of Delta-9-Tetrahydrocannabinol For Transmucosal Delivery, Sampada Bhaskar Upadhye 2010 University of Mississippi

Preparation And Characterization Of Lyophilized Cyclodextrin Complexes Of A Hemisuccinate Ester Of Delta-9-Tetrahydrocannabinol For Transmucosal Delivery, Sampada Bhaskar Upadhye

Electronic Theses and Dissertations

Delta-9- Tetrahydrocannabinol (THC) is the primary active ingredient of the plant Cannabis sativa (marijuana), responsible for the majority of the pharmacological effects. The most promising clinical applications of THC approved by the Food and Drug Administration (FDA) are for the control of nausea and vomiting associated with chemotherapy and for appetite stimulation of AIDS patients suffering from anorexia and wasting syndrome. The only dosage form currently approved by FDA is an oral, soft gelatin capsule (e.g. Marinol®). In addition, orally administered THC from Marinol® has shown slow and variable absorption due to low oral solubility and first pass metabolism ...


Willingness To Influence Indication-Based Off-Label Prescribing: An Investigation Of Hospital Pharmacists, Ram Sankar Basak 2010 University of Mississippi

Willingness To Influence Indication-Based Off-Label Prescribing: An Investigation Of Hospital Pharmacists, Ram Sankar Basak

Electronic Theses and Dissertations

Off-label prescribing is a common and legal practice in the United States. However, off-label prescribing occurs oftentimes with inadequate evidence of effectiveness. Such practice, especially when prescribing for disease conditions different from approved clinical indications (indication-based off-label prescribing), brings about controversy and raises different issues with various stakeholders. Although indication-based off-label prescribing offers advantages in terms of providing innovative therapy, it raises concerns because the safety and efficacy of such use may not be evaluated adequately. Thus, the objective of the study was to examine whether pharmacists are willing to influence physicians while evaluating an indication-based off-label medication order. Based ...


A Single Case Study Of A Three Year Coordinated School Health Program At A Rural North Mississippi Elementary School, Sandra Lena Howell 2010 University of Mississippi

A Single Case Study Of A Three Year Coordinated School Health Program At A Rural North Mississippi Elementary School, Sandra Lena Howell

Electronic Theses and Dissertations

The single case study presents the story of the implementation of a three year Coordinated School Health Program (CSHP) at a rural North Mississippi school. The school was recognized by the Mississippi Department of Education, Office of Healthy Schools, as one of ten selected model Mississippi healthy schools. An awarded grant of one hundred thousand dollars funded the implementation of the CSHP over a three year period. The study examined the impact of the CSHP on the students, staff, and personnel. Two types of data were collected and analyzed including archived documents and interviews conducted with five members of the ...


A Case Of Erythema Elevatum Diutinumassociated With Iga Monoclonal Gammopathy And Multiple Myeloma, Shadi Jarjous MD, Cheryl Bloomfield MD, James Ross MD, FACP 2010 Lehigh Valley Health Network

A Case Of Erythema Elevatum Diutinumassociated With Iga Monoclonal Gammopathy And Multiple Myeloma, Shadi Jarjous Md, Cheryl Bloomfield Md, James Ross Md, Facp

Department of Medicine

No abstract provided.


Pramlintide In The Management Of Obesity, Melissa C. Jones, Heather F. DeBellis, Kimberly L. Barefield 2010 Philadelphia College of Osteopathic Medicine

Pramlintide In The Management Of Obesity, Melissa C. Jones, Heather F. Debellis, Kimberly L. Barefield

PCOM Scholarly Papers

Obesity is a common problem that can lead to numerous comorbid conditions, including Type 2 diabetes. Currently, there are few pharmacologic options available to help obese patients lose weight. Pramlintide is an injectable, amylin analogue that is indicated in patients with Type 1 and Type 2 diabetes for use in conjunction with insulin to improve glycemic control. In addition to helping patients decrease hemoglobin A1c levels, pramlintide has also been shown to minimize weight gain, especially in patients with Type 2 diabetes. Studies have been conducted in various patient types, including those patients without diabetes, and the drug tends to ...


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