Medicine and Health Sciences Commons^™

Chronic Depression: Responses To Transcranial Magnetic Stimulation And Considerations Of A Developmental Construction Of Self, Jasmina Markovski

Theses

There are two components to this thesis, one applied and one theoretical: (1) to investigate whether treatment response to Transcranial Magnetic Stimulation (TMS) can be predicted by depressive subtypes and (2) to explore the contribution of personality to chronic depression. Participants were 67 adults volunteering for clinical trials of TMS. In the first component individuals were separated into two groups, melancholic and non-melancholic. Both groups showed a significant reduction in their depressive symptomatology following treatment. Individuals had also been administered a measure for Depressive Personality Disorder (DPD). When the individuals were classified based on DPD groups, both those with a ...

Medical Education Digest, Vol. 12 No. 2 (March/April 2010), Nova Southeastern University

Medical Education Digest

No abstract provided.

Reconstructability Analysis As A Tool For Identifying Gene-Gene Interactions In Studies Of Human Diseases, Stephen Shervais, Patricia L. Kramer, Shawn K. Westaway, Nancy J. Cox, Martin Zwick

Systems Science Faculty Publications and Presentations

There are a number of common human diseases for which the genetic component may include an epistatic interaction of multiple genes. Detecting these interactions with standard statistical tools is difficult because there may be an interaction effect, but minimal or no main effect. Reconstructability analysis (RA) uses Shannon’s information theory to detect relationships between variables in categorical datasets. We applied RA to simulated data for five different models of gene-gene interaction, and find that even with heritability levels as low as 0.008, and with the inclusion of 50 non-associated genes in the dataset, we can identify the interacting ...

Building A Bridge Between Physical Therapists And Fitness Professionals: The Development Of A Business Plan For San Luis Sports Therapy Clinics, Ashley August Fittz

Master's Theses and Project Reports

The purpose of this project was to create a business plan for a profitable, self-sustaining, program to build a bridge between physical therapists and fitness professionals.

The Quick Fit Program was a new service for the existing business San Luis Sports Therapy. The program was designed to be implemented within each of the company’s physical therapy clinics in California using existing personnel and resources. The Quick Fit Program is one way in which physical therapy practices can diversify the services they offer to keep pace with the changing landscape of healthcare.

Clients in the Quick Fit Program would receive ...

Can Urethral Retroresistance Pressures Predict Midurethral Sling Outcomes?, Patrick J. Culligan, Jennifer Lewis-Priestley, Linda Blackwell, Susan B. Tate

Faculty Publications

OBJECTIVE: To determine whether preoperative urethral resistance pressure (URP) measurements could predict success or failure of a tension-free vaginal tape (TVT) sling.

METHODS: Subjects came from a previously published study comparing URP measurements to a validated urinary incontinence symptom survey (UISS). We contacted patients from that study to determine whether they had subsequently undergone TVT surgery. Within that cohort, we determined the “current” (i.e., postoperative) UISS and Sandvik urinary incontinence severity score. Success of a TVT sling in this group was defined in 4 ways: (1) postoperative UISS score < 3, (2) postoperative UISS score < 75% of the preoperative score, (3) postoperative Sandvik score < 6, and (4) postoperative Sandvik score < 2. These definitions of “success” were compared across demographic and treatment variables using the Student’s t test, ANOVA, χ 2 and ROC curves.

RESULTS: We contacted 69 women who had in fact received ...

Orthopaedic Surgeons And The Medical Device Industry: The Threat To Scientific Integrity And The Public Trust, Richard H. Gelberman, David Samson, Sohail K. Mirza, John J. Callaghan, Vincent D. Pellegrini

Open Access Publications

No abstract provided.

The President's Emergency Plan For Aids Relief (Pepfar): A Social Work Ethical Analysis And Recommendations, Robert J. Barney, Stephan L. Buckingham, Judith M. Friedrich, Lisa M. Johnson, Michael A. Robinson, Bibhuti K. Sar

The Journal of Sociology & Social Welfare

The President's Emergency Plan for AIDS Relief (PEPFAR) is the most recent international social program instituted by the U.S. Government to combat HIV/AIDS. Since its inception in 2003, this foreign policy initiative has dedicated $63 billion for HIV/AIDS prevention and treatment in foreign countries. Despite PEPFAR's many accomplishments, it continues to promote controversial prevention strategies. This paper analyzes these prevention strategies, utilizing social work values as described in the NASW Code of Ethics. Policy, practice, and research implications are discussed.

Maternal Consumption Of Canola Oil Suppressed Mammary Gland Tumorigenesis In C3(1) Tag Mice Offspring, Gabriela Ion, Juliana A. Akinsete, W. Elaine Hardman

Biochemistry and Microbiology

Background: Maternal consumption of a diet high in omega 6 polyunsaturated fats (n-6 PUFA) has been shown to increase risk whereas a diet high in omega 3 polyunsaturated fats (n-3 PUFA) from fish oil has been shown to decrease risk for mammary gland cancer in female offspring of rats. The aim of this study was to determine whether increasing n-3 PUFA and reducing n-6 PUFA by using canola oil instead of corn oil in the maternal diet might reduce the risk for breast cancer in female offspring.

Methods: Female SV 129 mice were divided into two groups and placed on ...

Expanding Roles: Creating Innovative Partnerships To Improve Clinical Nursing Education (Clinical Education In Action), Louise Ward, Jane Petersen

School of Health and Human Sciences

No abstract provided.

Development Of Hong Kong Chinese Materia Medica (Hkcmm) Standards = 香港中藥材標準的制訂與發展, Hu-Biao Chen, Tao Yi

HKBU Staff Publication

The development of HKCMM standards is one of the achievements of developing Hong Kong into an international centre for Chinese medicine. In order to enable more people concerned to have an intimate knowledge of this standard, the author was invited to introduce the development of HKCMM standards to readers, including: 1) the history of the project and the basis for legislative supports; 2) the composition and operation of the regulatory division, the research institution and the evaluation committee; 3) the progress of HKCMM standards; 4) the contents and features of HKCMM standards.

在發展香港成為國際中醫藥中心的眾多成果中,香港中藥材標準(港標)的制訂是其中成果之一。為了讓更多相關人士了解和熟悉這個標準,本文作者應邀向讀者介紹港標制訂的以下內容,包括:1 ...

Increased Isolation Of Esbl Producing Klebsiella Pneumoniae With Emergence Of Carbapenem Resistant Isolates In Pakistan: Report From A Tertiary Care Hospital, Erum Khan, Muslima Ejaz, Afia Zafar, Kauser Jabeen, Sadia Shakoor, Raunaq Inayat, Rumina Hasan

Department of Pathology and Laboratory Medicine

OBJECTIVE: To report trends of extended spectrum beta lactamase (ESBL), multidrug resistant (MDR) ESBL and emergence of carbapenem resistant ESBL producing isolates of K. pneumoniae from Pakistan.

METHODS: Retrospective analysis of laboratory data was conducted (2002-2007). K. pneumoniae were isolated and identified from clinical samples using standard microbiological techniques. Antimicrobial susceptibility testing was performed by Kirby Bauer. ESBL was detected using combined disc method. Statistical analysis was performed using SPSS version 13.

RESULTS: 15914 K. pneumoniae isolates (2002-2007) were analyzed. Significant increase in ESBL and MDR ESBL producing K. pneumoniae (p = or < 0.0001) was observed. We found significant association of ESBL positive K. pneumoniae with age less than 10 years, males and blood isolates (p = 0.001). 0.4% (n=23) of ESBL positive isolates were carbapenem resistant.

CONCLUSIONS: Increase in ESBL and carbapenem resistant K ...

Magnetic Resonance Imaging Findings In Patients With Schizophrenia, Waseem Akhtar, Haider A Naqvi, Sajjad Hussain, Arif Ali, Nadeem Ahmad

Department of Radiology

OBJECTIVE: To determine structural abnormalities in the brain of patients with schizophrenia by Magnetic Resonance Imaging (MRI).

STUDY DESIGN: Comparative study.

PLACE AND DURATION OF STUDY: The Departments of Radiology and Psychiatry, the Aga Khan University Hospital, Karachi, from January 2007 to June 2008.

METHODOLOGY: Thirty-three cases of schizophrenia (n=33) and thirty-three age-matched controls, (n=33) were enrolled for this study. Screening Magnetic Resonance Imaging (MRI) of brain was done in order to see structural changes in brain matter. Findings were compared among groups using chi-square and Fisher's exact test with significance at p < 0.05.

RESULTS: Among the total ...

Comparison Of The Anti-Inflammatory And Anti-Nociceptive Effects Of Three Medicinal Plants Known As “Snow Lotus” Herb In Traditional Uighur And Tibetan Medicines, Tao Yi, Zhong-Zhen Zhao, Zhi-Ling Yu, Hu-Biao Chen

HKBU Staff Publication

Ethnopharmacological relevance: Saussurea involucrata (Kar. et Kir.) Sch.-Bip. (Compositae) has long been used under the herbal name "Snow Lotus" for the treatment of rheumatoid arthritis, stomachache and dysmenorrhea in Uighur folk medicine. In traditional Tibetan medicine, Saussurea laniceps Hand.-Mazz. and Saussurea medusa Maxim. have also been used under the name "Snow Lotus" and prescribed for the treatment of pain and inflammatory conditions. Aim of the study: The present study evaluated the pharmacological effects of three species of "Snow Lotus" in experimental inflammation and pain models, and determined the chemical compounds that may correlate with their pharmacological activities. Materials ...

Four Country Healthcare-Associated Infection Prevalence Survey: Pneumonia And Lower Respiratory Tract Infections., Hilary Humphreys, R G. Newcombe, J Enstone, E Tm Smyth, G Mcilvenny, E Davies, R Spencer

Clinical Microbiology Articles

In 2006, the Hospital Infection Society was funded by the respective health services in England, Wales, Northern Ireland and the Republic of Ireland to conduct a prevalence survey of healthcare-associated infection (HCAI). Here, we report the prevalence of pneumonia and lower respiratory tract infection other than pneumonia (LRTIOP) in these four countries. The prevalence of all HCAIs was 7.59% (5743 out of 75 694). Nine hundred (15.7%) of these infections were pneumonia, and 402 (7.0%) were LRTIOP. The prevalence of both infections was higher for males than for females, and increased threefold from those aged <35 to those aged>85 years ...

Medially: A Provenance-Aware Remote Health Monitoring Middleware, Atanu Roy Chowdhury, Ben Falchuk, Archan Misra

Research Collection School Of Information Systems

This paper presents MediAlly, a middleware for supporting energy-efficient, long-term remote health monitoring. Data is collected using physiological sensors and transported back to the middleware using a smart phone. The key to MediAlly's energy efficient operations lies in the adoption of an Activity Triggered Deep Monitoring (ATDM) paradigm, where data collection episodes are triggered only when the subject is determined to possess a specified context. MediAlly supports the on-demand collection of contextual provenance using a novel low-overhead provenance collection sub-system. The behaviour of this sub-system is configured using an application-defined context composition graph. The resulting provenance stream provides valuable ...

On Pump Coronary Surgical Revascularization In A Patient With Chronic Immune Thrombocytopenic Purpura, Saulat Fatimi, Danesh K Kella, Marium Muzaffar, Hashim Muhammad Hanif

Section of Cardiothoracic Surgery

We performed on-pump coronary artery bypass graft surgery on a 54-year-old female, known case of chronic Idiopathic Thrombocytopenic Purpura (ITP), hypertension and dyslipidaemia who had presented to us with progressive exertional shortness of breath and chest pain. The decision of going on with CABG was made after two weeks of preoperative treatment with prednisolone. Her platelet counts pre-operatively and on the 4th post-operative day were 135 x 10(9)/L and 32 x 10(9)/L. She had an unremarkable post-operative recovery, without requiring whole blood or platelet transfusions. We recommend preoperative steroid treatment in patients with chronic ITP undergoing ...

Lpa Induces Il-6 Secretion From Aortic Smooth Muscle Cells Via An Lpa1-Regulated, Pkc-Dependent, And P38alpha-Mediated Pathway, F Hao, M Tan, D Wu, Xuemin Xu, Mei-Zhen Cui

Xuemin Xu

Lysophosphatidic acid (LPA) is a potent bioactive lysophospholipid. Accumulated evidence supports a role for LPA in inflammation. To profile LPA-induced cytokine production in vascular smooth muscle cells (SMCs), we used a cytokine antibody array system and found that LPA prominently induces the secretion of IL-6 and monocyte chemoattractant protein (MCP)-1 from human aortic SMCs (HASMCs). The mechanism by which LPA induces MCP-1 expression in SMCs has been previously reported. However, LPA induction of IL-6 secretion from vascular SMCs and its regulatory mechanism are unknown. The present study reveals that LPA induces the expression of IL-6 mRNA and protein in ...

Diagnosis Of Aeromonas Hydrophila, Mycobacterium Species, And Batrachochytrium Dendrobatidis In An African Clawed Frog (Xenopus Laevis)., William Hill, Shelley Newman, Linden Craig, Chris Carter, Jane Czarra, Julie Brown

William Allen Hill

Here we describe diagnosis of concurrent infection with Aeromonas hydrophila, Mycobacterium spp., and Batrachochytrium dendrobatidis in a wild female Xenopus laevis captured in Chile and transported to the United States. After approximately 130 d in the laboratory, the frog was presented for dysecdysis and obtundation. After euthanasia, tissues were submitted for histopathologic evaluation and PCR analysis for B. dendrobatidis and Ranavirus. Clinically significant gross lesions included cutaneous ulcerations on the lip, right forelimb, and ventral chest. Microscopic findings included regionally extensive splenic necrosis, diffuse pneumonia, and fibrinous coelomitis all containing intralesional bacteria. PCR analysis yielded positive results for B. dendrobatidis ...

The Contribution Of Processing Impairments To Sli: Insights From Attention-Deficit/Hyperactivity Disorder, Janis Cardy, Rosemary Tannock, Andrew Johnson, Carla Johnson

Andrew M. Johnson

Slowed speed of processing and impaired rapid temporal processing (RTP) have been proposed to underlie specific language impairment (SLI), but it is not clear that these dysfunctions are unique to SLI. We considered the contribution of attention-deficit/hyperactivity disorder (ADHD), which frequently co-occurs with language impairments, to performances on processing tasks. School-aged children who had SLI without concurrent ADHD (n=14), ADHD without concurrent SLI (n=14), and typical development (TD, n=28) performed two nonverbal speeded tasks and one auditory RTP task. RTP impairments were found in many children with SLI and ADHD, and some children with TD. Children ...

Diversity In Laboratory Animal Science: Issues And Initiatives., L Alworth, K Ardayfio, A Blickman, L Greenhill, William Hill, P Sharp, R Talmage

William Allen Hill

Since diversity in the workplace began receiving scholarly attention in the late 1980s, many corporations and institutions have invested in programs to address and manage diversity. We encourage laboratory animal science to address the challenges and to build on the strengths that personal diversity brings to our field and workplaces. Diversity is already becoming increasingly relevant in the workplace and the laboratory animal science field. By addressing issues related to diversity, laboratory animal science could benefit and potentially fulfill its goals more successfully. To date, diversity has received minimal attention from the field as a whole. However, many individuals, workplaces ...