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Two Holocene Rock Shelter Deposits From The Knersvlakte, Southern Namaqualand, South Africa, Jayson Orton, Richard G. Klein, Alex Mackay, Steve E. Schwortz, Teresa E. Steele 2011 University of Cape Town

Two Holocene Rock Shelter Deposits From The Knersvlakte, Southern Namaqualand, South Africa, Jayson Orton, Richard G. Klein, Alex Mackay, Steve E. Schwortz, Teresa E. Steele

Faculty of Science, Medicine and Health - Papers: part A

This paper describes the first excavations into two Holocene Later Stone Age (LSA) deposits in southern Namaqualand. The limestone shelters afforded excellent preservation, and the LSA sites contained material similar in many respects to shelters in the Cederberg range to the south. Deposition at both sites was discontinuous with a mid-Holocene pulse in Buzz Shelter followed by contact-period deposits over a total depth of some 0.45 m. In Reception Shelter the 1.40 m deposit yielded a basal age in the fifth to eighth centuries BC with pottery and domestic cow contained within a strong pulse of occupation just ...


Infrared Stimulated Luminescence Measurements Of Single Grains Of K-Rich Feldspar For Isochron Dating, Bo Li, Sheng-Hua Li, Geoffrey A. T Duller, Ann G. Wintle 2011 University of Hong Kong

Infrared Stimulated Luminescence Measurements Of Single Grains Of K-Rich Feldspar For Isochron Dating, Bo Li, Sheng-Hua Li, Geoffrey A. T Duller, Ann G. Wintle

Faculty of Science, Medicine and Health - Papers: part A

This paper explores the use of single grain luminescence measurements in isochron dating of K-rich feldspars. The thermal stability of individual feldspar grains was investigated using pulse annealing methods, which appears to distinguish between K-rich and Na-rich feldspars. A good isochron fit was obtained using synthetic aliquots produced from the single grain data set and the age obtained based on an assumed K content of 13 ± 1% was in good agreement with that obtained using single aliquot measurements (and with other age control).


Opposing Actions Of Extracellular Signal-Regulated Kinase (Erk) And Signal Transducer And Activator Of Transcription 3 (Stat3) In Regulating Microtubule Stabilization During Cardiac Hypertrophy, D Ng, I Ng, B Badrian, T Tsoutsman, J McMullen, C Semsarian, M Bogoyevitch 2011 The University of Notre Dame Australia

Opposing Actions Of Extracellular Signal-Regulated Kinase (Erk) And Signal Transducer And Activator Of Transcription 3 (Stat3) In Regulating Microtubule Stabilization During Cardiac Hypertrophy, D Ng, I Ng, B Badrian, T Tsoutsman, J Mcmullen, C Semsarian, M Bogoyevitch

Medical Papers and Journal Articles

Excessive proliferation and stabilization of the microtubule (MT) array in cardiac myocytes can accompany pathological cardiac hypertrophy, but the molecular control of these changes remains poorly characterized. In this study, we examined MT stabilization in two independent murine models of heart failure and revealed increases in the levels of post-translationally modified stable MTs, which were closely associated with STAT3 activation. To explore the molecular signaling events contributing to control of the cardiac MT network, we stimulated cardiac myocytes with an a-adrenergic agonist phenylephrine (PE), and observed increased tubulin content without changes in detyrosinated (glutubulin) stable MT’s. In contrast, the ...


Model-Driven Safety Analysis Of Closed-Loop Medical Systems, Miroslav Pajic, Rahul Mangharam, Oleg Sokolsky, David Arney, Julian M. Goldman, Insup Lee 2011 University of Pennsylvania

Model-Driven Safety Analysis Of Closed-Loop Medical Systems, Miroslav Pajic, Rahul Mangharam, Oleg Sokolsky, David Arney, Julian M. Goldman, Insup Lee

Departmental Papers (CIS)

In modern hospitals, patients are treated using a wide array of medical devices that are increasingly interacting with each other over the network, thus offering a perfect example of a cyber-physical system. We study the safety of a medical device system for the physiologic closed-loop control of drug infusion. The main contribution of the paper is the verification approach for the safety properties of closed-loop medical device systems. We demonstrate, using a case study, that the approach can be applied to a system of clinical importance. Our method combines simulation-based analysis of a detailed model of the system that contains ...


Assessment Of Surfactant Use In Preterm Infants As A Marker Of Neonatal Intensive Care Unit Quality, Heather C. Kaplan, Scott A. Lorch, Jennifer Pinto-Martin, Mary E. Putt, Jeffrey H. Silber 2011 The Children's Hospital of Philadelphia

Assessment Of Surfactant Use In Preterm Infants As A Marker Of Neonatal Intensive Care Unit Quality, Heather C. Kaplan, Scott A. Lorch, Jennifer Pinto-Martin, Mary E. Putt, Jeffrey H. Silber

Health Care Management Papers

Background

Proposed neonatal quality measures have included structural measures such as average daily census, and outcome measures such as mortality and rates of complications of prematurity. However, process measures have remained largely unexamined. The objective of this research was to examine variation in surfactant use as a possible process measure of neonatal quality.

Methods

We obtained data on infants 30 to 34 weeks gestation admitted with respiratory distress syndrome (RDS) within 48 hours of birth to 16 hospitals participating in the Pediatric Health Information Systems database from 2001-2006. Models were developed to describe hospital variation in surfactant use and identify ...


Fitness And Adiposity As Predictors Of Functional Limitation In Adults, Andréa L. Maslow, Anna E. Price, Xuemei Sui, Duck-chul Lee, Ilkka Vuori, Steven N. Blair 2011 University of South Carolina - Columbia

Fitness And Adiposity As Predictors Of Functional Limitation In Adults, Andréa L. Maslow, Anna E. Price, Xuemei Sui, Duck-Chul Lee, Ilkka Vuori, Steven N. Blair

Faculty Publications

Background: This study examined the associations of body mass index (BMI), waist circumference (WC), and cardiorespiratory fitness (CRF) with incident functional limitation (IFL) in adults.

Methods: Patients (n = 2400), 30+ years [mean age, 45.2 (SD, 8.3); 12% women], completed a baseline health examination during 1979 to 1995. CRF was quantified by age- and sex-specific thirds for maximal treadmill exercise test duration. Adiposity was assessed by BMI and WC (grouped for analysis according to clinical guidelines). Incident IFL was identified from mail-back surveys during 1995, 1999, and 2004.

Results: After adjusting for potential confounders and either BMI or WC ...


Acute Impact Of Moderate-Intensity And Vigorous-Intensity Exercise Bouts On Daily Physical Activity Energy Expenditure In Postmenopausal Women, Xuewen Wang, Barbara J. Nicklas 2011 University of South Carolina - Columbia

Acute Impact Of Moderate-Intensity And Vigorous-Intensity Exercise Bouts On Daily Physical Activity Energy Expenditure In Postmenopausal Women, Xuewen Wang, Barbara J. Nicklas

Faculty Publications

This study determined whether performing a single moderate- or vigorous-intensity exercise bout impacts daily physical activity energy expenditure (PAEE, by accelerometer). Overweight/obese postmenopausal women underwent a 5-month caloric restriction and moderate- (n = 18) or vigorous-intensity (n = 18) center-based aerobic exercise intervention. During the last month of intervention, in women performing moderate-intensity exercise, PAEE on days with exercise (577.7 ± 219.7 kcal·d−1) was higher (P = .011) than on days without exercise (450.7 ± 140.5 kcal·d−1); however, the difference (127.0 ± 188.1 kcal·d−1) was much lower than the energy expended during exercise ...


Avoiding Irrational Neurolaw Exuberance: A Plea For Neuromodesty, Stephen Morse 2011 University of Pennsylvania

Avoiding Irrational Neurolaw Exuberance: A Plea For Neuromodesty, Stephen Morse

Neuroethics Publications

"In a 2002 editorial published in The Economist, the following warning was given: "Genetics may yet threaten privacy, kill autonomy, make society homogeneous and gut the concept of human nature. But neuroscience could do all of these things first." The genome was fully sequenced in 2001, and there has not been one resulting major advance in therapeutic medicine since. Thus, even in its most natural applied domain-medicine-genetics has not had the far-reaching consequences that were envisioned. The same has been true for various other sciences that were predicted to revolutionize the law, including behavioral psychology, sociology, psychodynamic psychology, and others ...


Case Management, David A. Smelson, Douglas M. Ziedonis, Anna Kline, Leon Sawh, Stephanie Rodrigues 2011 University of Massachusetts Medical School

Case Management, David A. Smelson, Douglas M. Ziedonis, Anna Kline, Leon Sawh, Stephanie Rodrigues

Psychiatry Publications and Presentations

This chapter describes the roles and responsibilities of the MISSION-VET Case Manager and how it relates to MISSION-VET service delivery. The chapter begins with an overview of the MISSION-VET Case Manager’s responsibilities. Settings in which MISSION-VET can be delivered and implications for case management are then reviewed. The importance of teamwork with the Peer Support Specialist is stressed, and the Case Manager’s role is distinguished from that of the Peer Support Specialist. The Chapter then reviews each of the Case Manager’s primary responsibilities. Because case management is seen as the foundation of the MISSION-VET model, this chapter ...


Validation Of Updated Partin’S Table In Pakistani Patients Undergoing Radical Prostatectomy For Prostate Cancer, Nazim Muhammad, Farhat Abbas, Nuzhat Faruqui, Muhammad Islam, Zubair Ahmad 2011 Aga Khan University

Validation Of Updated Partin’S Table In Pakistani Patients Undergoing Radical Prostatectomy For Prostate Cancer, Nazim Muhammad, Farhat Abbas, Nuzhat Faruqui, Muhammad Islam, Zubair Ahmad

Section of Urology

Objectives: To establish the usefulness and validity of 2007 Partin’s table in our population with prostate cancer.
Materials and methods: Between January 1998 to June 2009, all patients with clinically localized carcinoma prostate who were treated with intent of radical retro-pubic prostatectomy (RRP) were included. Clinical, operative and pathological data was gathered. All biopsy and final histopathology Gleason scores were re-assigned in a double blind manner. Pre-operative serum PSA, TNM clinical stage and biopsy Gleason scores were plotted on Partin’s table and its predictive value and pathological findings of specimen were compared and analyzed by using Receiver operating ...


An Evaluation Of The Usability Of A Computerized Decision Support System For Nursing Homes, M. Fossum, M. Ehnfors, Ann L. Fruhling, A. Ehrenberg 2011 Orebro University

An Evaluation Of The Usability Of A Computerized Decision Support System For Nursing Homes, M. Fossum, M. Ehnfors, Ann L. Fruhling, A. Ehrenberg

Interdisciplinary Informatics Faculty Publications

Background: Computerized decision support systems (CDSSs) have the potential to significantly improve the quality of nursing care of older people by enhancing the decision making of nursing personnel. Despite this potential, health care organizations have been slow to incorporate CDSSs into nursing home practices.

Objective: This study describes facilitators and barriers that impact the ability of nursing personnel to effectively use a clinical CDSS for planning and treating pressure ulcers (PUs) and malnutrition and for following the suggested risk assessment guidelines for the care of nursing home residents.

Methods: We employed a qualitative descriptive design using varied methods, including structured ...


Table Of Contents, 2011 University of South Carolina

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Repression Of Mammary Stem/Progenitor Cells By P53 Is Mediated By Notch And Separable From Apoptotic Activity, Karen Dunphy, L. Tao, C. Bigelow, H. Yan, J.D. Jerry 2011 University of Massachusetts - Amherst

Repression Of Mammary Stem/Progenitor Cells By P53 Is Mediated By Notch And Separable From Apoptotic Activity, Karen Dunphy, L. Tao, C. Bigelow, H. Yan, J.D. Jerry

Karen Dunphy

Breast cancer is the most common tumor among women with inherited mutations in the p53 gene (Li-Fraumeni syndrome). The tumors represent the basal-like subtype, which has been suggested to originate from mammary stem/progenitor cells. In mouse mammary epithelium, mammosphere-forming potential was increased with decreased dosage of the gene encoding the p53 tumor suppressor protein (Trp53). Limiting dilution transplantation also showed a 3.3-fold increase in the frequency of long-term regenerative mammary stem cells in Trp53−/− mice. The repression of mammospheres by p53 was apparent despite the absence of apoptotic responses to radiation indicating a dissociation of these two activities ...


The Nurse's Knowledge Of Blood Conservation As A Part Of Blood Management, Lindsey Putnam Austin 2011 Gardner-Webb University

The Nurse's Knowledge Of Blood Conservation As A Part Of Blood Management, Lindsey Putnam Austin

Nursing Theses and Capstone Projects

Medicine has historically regarded blood transfusion as an integral component of major surgery or illness. However, clinical studies have shown that allogeneic blood transfusions are associated with increased morbidity and decreased survival. Knowledge of this research and the concepts of blood conservation so as to avoid unnecessary blood transfusions is needed in order to deliver holistic care and serve as patient advocate. This knowledge reaches every specialty of nursing care.

This study of the nurse's knowledge of blood conservation as a part of blood management utilizes The Conservation Model developed by Myra E. Levine in 1973. Levine's work ...


The Effects Of Education And Training On Nurses' Perception Of Lateral Violence In The Healthcare Field, Tamara Cook 2011 Gardner-Webb University

The Effects Of Education And Training On Nurses' Perception Of Lateral Violence In The Healthcare Field, Tamara Cook

Nursing Theses and Capstone Projects

The effects of lateral violence are costly for all aspects of the healthcare profession. Lateral violence is an act of aggression directed towards another nurse. Educating nurses of lateral violence and its appearance may prove to increase nurse's perception of lateral violence therefore decreasing its occurrence. This study will explore the effects of education and training on nurses' perception of lateral violence in the healthcare field. Lateral violence threatens the integrity of each nurse, the nursing profession, and the organization. Increasing the awareness of lateral violence attempts to make a culture change among nurses in the healthcare profession. Minimizing ...


The Incidence Of Individual Sexually Based Counseling By School Nurses In An Urban School System, Tiffany Dunlap 2011 Gardner-Webb University

The Incidence Of Individual Sexually Based Counseling By School Nurses In An Urban School System, Tiffany Dunlap

Nursing Theses and Capstone Projects

The purpose of this study is to evaluate the incidence of individual counseling on sexual issues by school nurses in a large, urban, public school system in the Southeastern United States (U.S). Utilizing a descriptive, non-experimental method for the study, a secondary data analysis was conducted by the researcher using information self-reported by 117 school nurses regarding individual counseling of students in grades kindergarten through twelve on sexual topics. The topics included in the study were pregnancy, puberty/reproductive health and sexual abuse. There was a relationship established between grade level and rate of individual counseling. School nurses in ...


What Is The Caregivers' (Certified Nursing Assistant) Perception Of Their Role While Caring For A Patient In The Household Model?, Daniyele Feaster 2011 Gardner-Webb University

What Is The Caregivers' (Certified Nursing Assistant) Perception Of Their Role While Caring For A Patient In The Household Model?, Daniyele Feaster

Nursing Theses and Capstone Projects

This was a mixed design study that assessed the caregivers' perception of their role while caring for patients in the household model. A sample of 12 caregivers currently employed in a long-term care facility operating in the household model was asked to complete a survey and answer 11 questions during a one on one interview. This interview tool allowed the caregivers the opportunity to rate their personal experiences, environment and express their feelings associated with their role as a certified nursing assistant working in a household model. The results indicated that the caregivers enjoyed working in the household environment and ...


Preparing The New Graduate Nurse Entering Critical Or Progressive Care Practice Areas: What Is The Effect Of Blended Orientation Approaches On Their Level Of Self-Confidence And Satisfaction With Current Orientation Methods?, Jennifer L. Forbes 2011 Gardner-Webb University

Preparing The New Graduate Nurse Entering Critical Or Progressive Care Practice Areas: What Is The Effect Of Blended Orientation Approaches On Their Level Of Self-Confidence And Satisfaction With Current Orientation Methods?, Jennifer L. Forbes

Nursing Theses and Capstone Projects

The transition from student nurse to professional nurse is often difficult for the new graduate especially if transitioning into critical or progressive care areas of practice. It is imperative for new graduates to receive a clinical orientation that meets their educational and transitional needs. The orientation process should provide them with a strong foundation in critical or progressive care practices. Educators are challenged to provide educational opportunities while accommodating diverse learning needs and continuing to maintain competency that ensures the highest quality of patient care and improved patient care outcomes.

New graduate nurses hired into the critical or progressive care ...


Parental Perception Of Childhood Obesity And The School's Role On Prevention And Interventions In Childhood Obesity, Monique Jones 2011 Gardner-Webb University

Parental Perception Of Childhood Obesity And The School's Role On Prevention And Interventions In Childhood Obesity, Monique Jones

Nursing Theses and Capstone Projects

Childhood obesity is a major health crisis that is becoming an epidemic among children and adolescents. Interventions must begin early and focus on prevention strategies to achieve the goal of increasing quality years of life for today's children and families. Parents with children in a local after school Boys & Girls club were surveyed regarding their perception of childhood obesity, the causes of childhood obesity, and the school's role in the prevention and treatment of childhood obesity. More than 90% of the participants identified inactivity, poor eating behavior, eating too much, and lack of money to buy nutritious foods ...


Protocol Adherence During Inter-Facility Transfer Of Acute Ischemic Stroke Patients Treated With Iv Rtpa, Robin Reed Jones 2011 Gardner-Webb University

Protocol Adherence During Inter-Facility Transfer Of Acute Ischemic Stroke Patients Treated With Iv Rtpa, Robin Reed Jones

Nursing Theses and Capstone Projects

Stroke is a common and serious health disorder, affecting approximately 795,000 people in the United States every year. Intravenous recombinant tissue plasminogen activator (IV rtPA) is the only FDA approved thrombolytic for treating acute ischemic stroke within 3 hours of symptom onset. Patients treated at rural health centers are often transported within hours to the closest primary stroke center. The purpose of this study was to evaluate the structure, process and outcomes related to the inter-facility transport of ischemic stroke patients treated with intravenous rtPA. The Quality-Caring Model© was the guiding framework.

A quantitative, retrospective, non-experimental analysis of inter-facility ...


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