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A Framework For Fetecting Interactions Between Co-Incident Clinical Processes, Aditya K. Ghose, Kerry Hinge, Andrew Alexis Miller 2010 University of Wollongong

A Framework For Fetecting Interactions Between Co-Incident Clinical Processes, Aditya K. Ghose, Kerry Hinge, Andrew Alexis Miller

Graduate School of Medicine - Papers (Archive)

The detection of treatment conflicts between multiple treatment protocols that are co-incident is a difficult and open problem that is particularly exacerbated regarding the treatment of multiple medical conditions co-occurring in aged patients. For example, a clinical protocol for prostate cancer treatment requires the administration of androgen-suppressing medication, which may negatively interact with another, co-incident protocol if the same patient were being treated for renal disease via haemodialysis, where androgen-enhancers are frequently administered. These treatment conflicts are subtle and difficult to detect using automated means. Traditional approaches to clinical decision support would require significant clinical knowledge. In this paper, the ...


The Complete Ethical Framework For End-Of-Life Care, Joan McCarthy, Mary Donnelly, Dolores Dooley, Louise Campbell, David Smith, Catherine O'Neill, Christina Quinlan, John Weafer 2010 University College Cork

The Complete Ethical Framework For End-Of-Life Care, Joan Mccarthy, Mary Donnelly, Dolores Dooley, Louise Campbell, David Smith, Catherine O'Neill, Christina Quinlan, John Weafer

General Practice Reports

The Ethical Framework for End-of-life Care is part of a national programme, the Hospice Friendly Hospitals Programme (HfH) of the Irish Hospice Foundation, which is intended to improve the culture of care and organization regarding dying, death and bereavement in Irish hospitals. The Framework is an educational resource that consists of eight Modules of Learning for health professionals, patients, families and the general public. The Framework is the outcome of a unique collaboration between University College Cork, the Royal College of Surgeons in Ireland and the Irish Hospice Foundation, with contributions from ethicists, legal experts, theologians, sociologists and clinicians. It ...


A Targeted E-Learning Program For Surgical Trainees To Enhance Patient Safety In Preventing Surgical Infection., Seamus M. McHugh, Mark Corrigan, Borislav D. Dimitrov, Seamus Cowman, Sean Tierney, Hilary Humphreys, Arnold DK Hill 2010 Royal College of Surgeons in Ireland

A Targeted E-Learning Program For Surgical Trainees To Enhance Patient Safety In Preventing Surgical Infection., Seamus M. Mchugh, Mark Corrigan, Borislav D. Dimitrov, Seamus Cowman, Sean Tierney, Hilary Humphreys, Arnold Dk Hill

General Practice Articles

INTRODUCTION: Surgical site infection accounts for 20% of all health care-associated infections (HCAIs); however, a program incorporating the education of surgeons has yet to be established across the specialty.

METHODS: An audit of surgical practice in infection prevention was carried out in Beaumont Hospital from July to November 2009. An educational Web site was developed targeting deficiencies highlighted in the audit. Interactive clinical cases were constructed using PHP coding, an HTML-embedded language, and then linked to a MySQL relational database. PowerPoint tutorials were produced as online Flash audiovisual movies. An online repository of streaming videos demonstrating best practice was made ...


Augmentation Therapy For Alpha-1 Antitrypsin Deficiency—Not Enough Evidence To Support Its Use Yet!, Cormac McCarthy, Borislav D. Dimitrov 2010 Beaumont Hospital, Dublin

Augmentation Therapy For Alpha-1 Antitrypsin Deficiency—Not Enough Evidence To Support Its Use Yet!, Cormac Mccarthy, Borislav D. Dimitrov

General Practice Articles

No abstract provided.


2010 Cancer Care Annual Report, Children's Mercy Hospital 2010 Children's Mercy Kansas City

2010 Cancer Care Annual Report, Children's Mercy Hospital

Cancer Center Annual Reports

Annual report of cancer care and oncology services at the Children's Mercy Hospital, Kansas City MO, a pediatric medical center.


2010 Community Benefit Annual Report: Redefining Pediatric Medicine One Child At A Time, Children's Mercy Hospital 2010 Children's Mercy Kansas City

2010 Community Benefit Annual Report: Redefining Pediatric Medicine One Child At A Time, Children's Mercy Hospital

Community Benefits

Fiscal year report on the community benefits provided by Children's Mercy Kansas City to the communities in the Kansas City region.


A Novel Method Of Evaluating Competency In Information Literacy, Drew Keister MD, Julie Dostal MD, Elissa Foster PhD 2010 Lehigh Valley Health Network

A Novel Method Of Evaluating Competency In Information Literacy, Drew Keister Md, Julie Dostal Md, Elissa Foster Phd

Department of Family Medicine

No abstract provided.


Community Needs Assessment Of Mayasandra Village, Karnataka, India, Alexander Hernandez Holl 2010 University of Kentucky

Community Needs Assessment Of Mayasandra Village, Karnataka, India, Alexander Hernandez Holl

MPA/MPP Capstone Projects

No executive summary.


Parenting Adolescents, Sandra D'Angelo, Hatim A. Omar 2010 University of Kentucky

Parenting Adolescents, Sandra D'Angelo, Hatim A. Omar

Pediatrics Faculty Publications

The period of adolescence is often thought to be one of intense stress and turmoil. Yet many parents and teens negotiate this developmental stage without extreme family conflict and without sacrificing close relationships. This review summarizes a portion of the literature on parent-adolescent relationships, focusing on monitoring and control of adolescent behavior and parenting style. Basic principles to emphasize when working with adolescents and parents are also included.


The Vampire Adolescent, Megan White, Hatim A. Omar, Joav Merrick 2010 University of Kentucky

The Vampire Adolescent, Megan White, Hatim A. Omar, Joav Merrick

Pediatrics Faculty Publications

No abstract provided.


Characterization And Optimization Of Microelectrode Arrays For Glutamate Measurements In The Rat Hippocampus, Pooja Mahendra Talauliker 2010 University of Kentucky

Characterization And Optimization Of Microelectrode Arrays For Glutamate Measurements In The Rat Hippocampus, Pooja Mahendra Talauliker

University of Kentucky Doctoral Dissertations

An overarching goal of the Gerhardt laboratory is the development of an implantable neural device that allows for long-term glutamate recordings in the hippocampus. Proper L-glutamate regulation is essential for hippocampal function, while glutamate dysregulation is implicated in many neurodegenerative diseases. Direct evidence for subregional glutamate regulation is lacking in previous in vivo studies because of limitations in the spatio-temporal resolution of conventional experimental techniques. We used novel enzyme-coated microelectrode arrays (MEAs) for rapid measurements (2Hz) of extracellular glutamate in urethane-anesthetized rats. Potassium-evoked glutamate release was highest in the cornu ammonis 1 (CA1) subregion and lowest in the cornu ammonis ...


The Radiosensitization Effect Of Parthenolide In Prostate Cancer: Implications For Selective Cancer Killing By Modulation Of Intracellular Redox State, Yulan Sun 2010 University of Kentucky

The Radiosensitization Effect Of Parthenolide In Prostate Cancer: Implications For Selective Cancer Killing By Modulation Of Intracellular Redox State, Yulan Sun

University of Kentucky Doctoral Dissertations

Parthenolide (PN), a major active component of the traditional herbal medicine feverfew, has been shown to have anti-inflammatory and anti-tumor properties. More remarkably, the cytotoxicity of PN seems selective to tumor cells but not their normal cell counterparts. In the present study, we investigate whether and how PN selectively enhances tumor sensitivity to radiation therapy by using prostate cancer cells LNCaP, DU145 and PC3, as well as normal prostate epithelial cells PrEC.

Our study demonstrates that inhibition of NF-κB pathway and suppression of its downstream target MnSOD are common mechanisms for the radiosensitization effect of PN in prostate cancer cells ...


Modulation Of The Alpha-7 Nicotinic Acetylcholine Receptor Following Experimental Rat Brain Injury Improves Cellular And Behavioral Outcomes, Thomas Matt Woodcock 2010 University of Kentucky

Modulation Of The Alpha-7 Nicotinic Acetylcholine Receptor Following Experimental Rat Brain Injury Improves Cellular And Behavioral Outcomes, Thomas Matt Woodcock

University of Kentucky Doctoral Dissertations

Traumatic brain injury (TBI) is a leading cause of death and long-term disability worldwide, and survivors are often left with cognitive deficits and significant problems with day to day tasks. To date, therapeutic pharmacological treatments of TBI remain elusive despite numerous clinical trials. An improved understanding of the molecular and cellular response to injury may help guide future treatment strategies. One promising marker for brain injury is the translocator protein (TSPO), which is normally expressed at a low level, but is highly expressed following brain damage and is associated with neuroinflammation. The isoquinoline carboxamide PK11195 binds selectively to the TSPO ...


Inhibition Of Cholesterol Synthesis By Policosanol, Subhashis Banerjee 2010 University of Kentucky

Inhibition Of Cholesterol Synthesis By Policosanol, Subhashis Banerjee

University of Kentucky Doctoral Dissertations

Cholesterol is an essential component of the cell, but excessive blood levels are a major risk factor for the development of atherosclerotic plaques that can lead to heart disease and stroke, the foremost cause of premature death in Western societies. Policosanol, a mixture of very long chain alcohols derived from sugarcane, has gained considerable attention among the public as safe and effective means to reduce blood cholesterol levels, a belief based on some early clinical studies. My research investigates one possible mechanism by which policosanol might decrease blood cholesterol levels: the inhibition of cholesterol synthesis in the liver. Previous studies ...


Screen Door Medicine: The Informal Medical Consultation, Debra Faith Nickell 2010 University of Kentucky

Screen Door Medicine: The Informal Medical Consultation, Debra Faith Nickell

University of Kentucky Doctoral Dissertations

This study explores the phenomenon of the informal medical consultation, a communication event in which an individual asks for medical information, advice, or care from an off-duty health professional with whom the individual has no formal patient-provider relationship. Using surveys and interviews, the study describes these consultations from the perspective of the health care professional and the informal patient. The study explores foundational theories that offer explanations for the phenomenon. The theories considered include social support, decision-making, social exchange, perceived partner responsiveness to needs, and uncertainty management.

This study suggests health care providers perceive informal medical consultations to be more ...


Auditory Training At Home For Adult Hearing Aid Users, Anne D. Olson 2010 University of Kentucky

Auditory Training At Home For Adult Hearing Aid Users, Anne D. Olson

University of Kentucky Doctoral Dissertations

Research has shown that re-learning to understand speech in noise can be a difficult task for adults with hearing aids (HA). If HA users want to improve their speech understanding ability, specific training may be needed. Auditory training is one type of intervention that may enhance listening abilities for adult HA users.

The purpose of this study was to examine the behavioral effects of an auditory training program called Listening and Communication Enhancement (LACE™) in the Digital Video Display (DVD) format in new and experienced HA users. No research to date has been conducted on the efficacy of this training ...


Health Promotion And Health Education: Nursing Students’ Perspectives, Kathleen Ann Halcomb 2010 University of Kentucky

Health Promotion And Health Education: Nursing Students’ Perspectives, Kathleen Ann Halcomb

University of Kentucky Doctoral Dissertations

The purpose of this study was to determine student nurses’ perceptions of (1) the role of the nurse in health promotion, and (2) how the concept of health promotion is presented in nursing curricula. Research questions for this study included the following: 1) Can nursing students explain the difference between health education and health promotion? 2) What have nursing students been exposed to within their curriculum regarding health promotion? 3) What health promoting behaviors are nursing faculty role modeling as perceived by nursing students? 4) What is the role of the nurse in implementing health promotion as perceived by nursing ...


The Effect Of Acupressure On Constipation, Quality Of Life, And Depressive Symptoms In Cancer Patients With Constipation, Eun Jin Lee 2010 University of Kentucky

The Effect Of Acupressure On Constipation, Quality Of Life, And Depressive Symptoms In Cancer Patients With Constipation, Eun Jin Lee

University of Kentucky Doctoral Dissertations

Constipation is the most common gastrointestinal complaint in the United States, resulting in about 2 million annual visits to the doctor.

The purposes of this dissertation were to: 1) describe four theories of traditional Korean medicine; 2) review mechanisms of acupuncture and moxibustion and develop a conceptual model; 3) review findings from randomized controlled trials that tested the effects of acupressure used for the management of symptoms such nausea, pain, and dyspnea; 4) examine the reliability and validity of the Patient Health Questionnaire-9 (PHQ-9) in heart failure patients with constipation compared to those with gastrointestinal disease; 5) describe how Korean ...


Assessing Impact Of Affect Recognition On Therapeutic Relationship, Julianne V. Sutter 2010 University of Kentucky

Assessing Impact Of Affect Recognition On Therapeutic Relationship, Julianne V. Sutter

University of Kentucky Master's Theses

Therapeutic alliance and its relationship to client nonverbal behavior, specifically facial expressions, were examined. Therapist interpretation of the client nonverbal behavior, or affect, influences the therapeutic alliance and process. Based on a sample of clients from a graduate school therapy training facility, results suggest therapist training in facial expressions, and how they relate to client emotion, improve the therapeutic alliance between therapist and client. After a micro-expression training for therapists, clients reported higher life functioning on the Outcome Rating Scale (ORS) and an improved therapeutic alliance on the Session Rating Scale (SRS). Overall, these findings support the benefit of incorporating ...


Injury-Induced Hand Dominance Transfer, Kathleen E. Yancosek 2010 University of Kentucky

Injury-Induced Hand Dominance Transfer, Kathleen E. Yancosek

University of Kentucky Doctoral Dissertations

Hand dominance is the preferential use of one hand over the other for motor tasks. 90% of people are right-hand dominant, and the majority of injuries (acute and cumulative trauma) occur to the dominant limb, creating a double-impact injury whereby a person is left in a functional state of single-handedness and must rely on the less-dexterous, non-dominant hand. When loss of dominant hand function is permanent, a forced shift of dominance is termed injury-induced hand dominance transfer (I-IHDT).

Military service members injured in combat operation may face I-IHDT following mutilating injuries (crush, avulsion, burn and blast wounds) that result in ...


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