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Concurrent Intracranial And Spinal Arteriovenous Malformations: Report Of Two Pediatric Cases And Literature Review., Hussain Shallwani, Muhammad Z Tahir, Muhammad Ehsan Bari, Tanveer-Ul-Haq 2012 Aga Khan University

Concurrent Intracranial And Spinal Arteriovenous Malformations: Report Of Two Pediatric Cases And Literature Review., Hussain Shallwani, Muhammad Z Tahir, Muhammad Ehsan Bari, Tanveer-Ul-Haq

Section of Neurosurgery

Background:Concurrent intracranial and spinal arteriovenous malformations (AVMs) are very rare with only a few cases being reported in literature. Two of the rare concurrent intracranial and spinal AVM cases are presented. Case Discription: Case 1 is a 12-year-old girl with headache and motor disturbances in the lower limbs. Her spinal and brain angiogram was done and she was diagnosed to have a spinal AVM at level T8-T9 and an intracranial AVM in the left mesial temporal lobe. Her spinal AVM was embolized, while no treatment was given for her intracranial AVM. Case 2 is a 10-year-old girl who presented ...


Posttraumatic Stress And Myocardial Infarction Risk Perceptions In Hospitalized Acute Coronary Syndrome Patients, Donald Edmondson, Jonathan A. Shaffer, Ellen-ge Denton, Daichi Shimbo, Lynn Clemow 2012 Columbia University

Posttraumatic Stress And Myocardial Infarction Risk Perceptions In Hospitalized Acute Coronary Syndrome Patients, Donald Edmondson, Jonathan A. Shaffer, Ellen-Ge Denton, Daichi Shimbo, Lynn Clemow

Publications and Research

Posttraumatic stress disorder (PTSD) is related to acute coronary syndrome (ACS; i.e., myocardial infarction or unstable angina) recurrence and poor post-ACS adherence to medical advice. Since risk perceptions are a primary motivator of adherence behaviors, we assessed the relationship of probable PTSD to ACS risk perceptions in hospitalized ACS patients (n = 420). Participants completed a brief PTSD screen 3-7 days post-ACS, and rated their 1-year ACS recurrence risk relative to other men or women their age. Most participants exhibited optimistic bias (mean recurrence risk estimate between "average" and "below average"). Further, participants who screened positive for current PTSD (n ...


Hiv-1 R5 Tropism: Determinants, Macrophages, And Dendritic Cells: A Dissertation, Thomas A. Musich 2012 University of Massachusetts Medical School

Hiv-1 R5 Tropism: Determinants, Macrophages, And Dendritic Cells: A Dissertation, Thomas A. Musich

GSBS Dissertations and Theses

Around thirty years ago HIV-1 was identified, and from that point the known epidemic has grown to over 30 million infected individuals. Early on in the course of HIV-1 research, viruses were classified as either syncytia inducing, CXCR4-using, T-cell tropic or non-syncytia inducing, CCR5-using, macrophage tropic. Since that time, several groups have shown that this is an oversimplification. There is a great deal of diversity amongst CCR5-using HIV-1 variants. There remains a great deal to be discovered regarding HIV-1 CCR5-tropism and how this affects other aspects of HIV-1 infection.

The CD4 binding site (CD4bs) on the HIV-1 envelope plays a ...


Get Your Butt Off The Ground!: Consequences Of Cigarette Waste And Litter-Reducing Methods, Joyce Lee 2012 Pomona College

Get Your Butt Off The Ground!: Consequences Of Cigarette Waste And Litter-Reducing Methods, Joyce Lee

Pomona Senior Theses

Cigarette butts are rapidly accumulating on our planet; trillions of them are discarded every year. In this paper, I examine why cigarette litter is a problem. I first discuss the biodegradability of filters and its scientific basis, including ways to enhance degradation rates by chemically manipulating filters. I also talk about the persistence of cigarette chemicals and their potential toxic effects on children and animals. I consider other social, economic, and environmental consequences of cigarette filters and chemicals. Furthermore, I discuss various solutions smokers and non-smokers alike have created to address the problem of cigarette litter; these methods come from ...


The Association Between Marital Transitions, Body Mass Index, And Weight: A Review Of The Literature, Lauren Dinour, May May Leung, Gina Tripicchio, Sahar Khan, Ming-Chin Yeh 2012 CUNY Graduate Center

The Association Between Marital Transitions, Body Mass Index, And Weight: A Review Of The Literature, Lauren Dinour, May May Leung, Gina Tripicchio, Sahar Khan, Ming-Chin Yeh

Publications and Research

Objective: To examine the association between different marital transitions and changes in body mass index (BMI) and body weight.

Methods: A systematic literature search was conducted for peer-reviewed articles published between January 1990 and December 2011. Longitudinal studies were included if they compared dependent variables, such as BMI or weight, before and after a change in marital status.

Results: Twenty articles were included: 4 articles described only transitions into marriage and/or cohabitation, 2 articles described only transitions out of marriage and/or cohabitation, and 14 articles described both. Overall, transitions into marriage were associated with weight gain, whereas transitions ...


Patient Safety Competencies In Rural Asn Students: An Evidence-Based Curricular Innovation, Janeen Berndt 2012 Valparaiso University

Patient Safety Competencies In Rural Asn Students: An Evidence-Based Curricular Innovation, Janeen Berndt

Evidence-Based Practice Project Reports

Hospital clinical experiences are important events in prelicensure nursing education. Benefits include the opportunity for students to experience actual nursing responsibilities, immersion into environment, and professional socialization. However, challenges in finding appropriate clinical experiences include competition over clinical sites, decreasing patient acuity, and high student-faculty ratios. Rural schools of nursing have these challenges and those inherent in rural environments such as limited health care access, restricted critical access hospitals, and limited resources. The purpose of this evidence-based practice project was to plan, implement, and evaluate the use of a series of patient care simulations as an educational intervention to improve ...


Pharmacy And Empathy: Evaluating The Impact Of A Pharmacy Student's Project In A Service-Learning Course, Carly D'Agostino 2012 Butler University

Pharmacy And Empathy: Evaluating The Impact Of A Pharmacy Student's Project In A Service-Learning Course, Carly D'Agostino

Undergraduate Honors Thesis Collection

Background: Empathy is taking on a larger role in the pharmaceutical field as pharmacists place emphasis on patient centered care. Service-learning courses can expose pharmacy students to future patients, allowing them to interact and develop empathy. While this study suggests service-leaming can foster empathy, further research is needed to assess the specific outcome of empathy as a result of incorporating a project in a service-learning course for pre-pharmacy students.

Objective: To evaluate the effect on a pharmacy student's empathy after completing a one-on-one patient interview project during a service-learning experience. A secondary objective is to assess tile validity of ...


Linguistic Devices, Emotionality, And Memorability Of Computer Mediated Communication, Angela M. Mion 2012 Butler University

Linguistic Devices, Emotionality, And Memorability Of Computer Mediated Communication, Angela M. Mion

Undergraduate Honors Thesis Collection

I examined whether college students use shortcuts, pragmatics, and errors in text messages differently depending on their gender and the emotionality of the message. Results indicate that the prevalence of particular shortcuts differed across happy, sad, and angry messages, but gender did not influence use of linguistic devices. In a second study, I examined the emotionality and memorability of text messages versus voicemails. Results indicate that texts may be remembered better than voicemails, and happy, sad, and angry messages may be remembered differently by men and women.


Expressed Emotion And Attitudes Toward Body Image And Food, Toni Marie Maraldo 2012 Butler University

Expressed Emotion And Attitudes Toward Body Image And Food, Toni Marie Maraldo

Undergraduate Honors Thesis Collection

In numerous studies over the years, body image and dysfunctional attitudes toward food have shown to be related to the genesis of eating disorders. Recent research has particularly focused on the influence that families have on both the development of eating disorders as well as their impact on their child's body image and eating attitudes. In general, higher levels of expressed emotion are often found in families with children who have either anorexia nervosa or bulimia nervosa. However, there is a lack of research on sub-clinical populations. Therefore, the purpose of this study is to analyze the influence that ...


Safety Of Saccharomyces Boulardii (Florastor) In Solid Organ Transplant Patients, Nicole Marie Dores 2012 Butler University

Safety Of Saccharomyces Boulardii (Florastor) In Solid Organ Transplant Patients, Nicole Marie Dores

Undergraduate Honors Thesis Collection

Probiotics have been promoted for use in many gastrointestinal ailments. Most studies find probiotics safe for human use, reporting no severe adverse effects. However, probiotics are live microorganisms and thus have the potential to cause infection. Transplant recipients are considered at high risk for infectious complications from probiotics due to the immunosuppressive medications used to prevent organ rejection. Nonetheless, clinicians are currently utilizing probiotics in the transplant population, due to their benefit in gastrointestinal disorders, particularly recurrent Clostridium difficile. Limited knowledge and paucity of prospective trials in this patient population demands the need for completion of studies to identify the ...


Over-The-Counter Non-Steroidal Anti-Anflammatory Drugs In Adolescent Athletes, Anna Christine Parada 2012 Butler University

Over-The-Counter Non-Steroidal Anti-Anflammatory Drugs In Adolescent Athletes, Anna Christine Parada

Undergraduate Honors Thesis Collection

Non-steroidal anti-inflammatory drugs (NSAIDs) are common medications used by the general population due their anti-inflammatory and analgesic properties. These are especially popular in athletes since they are not prohibited in many rules of athletic competition. Over-the-counter (OTC) NSAIDs comprise several drugs that may be purchased without a prescription. These are often over-utilized by the general population due to their accessibility and relatively low cost. The unsuspecting victims are the children, especially adolescent athletes, who deem OTC NSAIDs safe without realizing the potential adverse effects of inappropriate consumption of these medications. This article reviews the approved indications and side effects of ...


P-Glycoprotein Functional Studies To Evaluate The Effect Of Cyclosporine Emulsion Formulations On Reversal Of Resistance In The Multidrug Resistant Cancer Cell Line Mes-Sa-Dx5, Katherine E. Cich 2012 Butler University

P-Glycoprotein Functional Studies To Evaluate The Effect Of Cyclosporine Emulsion Formulations On Reversal Of Resistance In The Multidrug Resistant Cancer Cell Line Mes-Sa-Dx5, Katherine E. Cich

Undergraduate Honors Thesis Collection

Background: The overexpression of an efflux protein, p-glycoprotein (P-gp), is a leading cause of multi drug resistance (MDR). This research project is based on designing emulsions containing optimal doses of cyclosporine (CyA) and Pluronic® P-85 (P85), two agents found to be effective in inhibiting P-gp. Study

Objective: To investigate whether CyA exposure affects the quantity or functionality of P-gp in vitro.

Methods: To study the functionality of P-gp, MDR cells were incubated with CyA solutions containing the P-gp substrate and fluorescent dye Rhodamine 123 (RI23). P-gp inhibition was measured by fluorescence spectrophotometry, which indicates the accumulation of R123 inside the ...


Delivering Quality Care: The Roles And Future Of Midwives In Southern California, Abigail Jones 2012 Scripps College

Delivering Quality Care: The Roles And Future Of Midwives In Southern California, Abigail Jones

Scripps Senior Theses

The United States is ranked 27th in the world for maternal mortality, yet spends twice as much on maternity care services as countries with better maternal health indicators. Stuck in a technocratic and physician-dominated maternity care system, the U.S. depends on expensive technologies to control birth out of fear of pain and litigation, costing Americans billions of dollars and depriving women of the opportunity to have a transformative birth experience. Through an analysis of the medicalization of birth and the current biomedical model in birth, in conjunction with open-ended interviews with 5 hospital midwives and 3 homebirth midwives ...


The Association Between Emotional Intelligence And Sexual Risk Behavior Among Undergraduate College Students In The Greater Los Angeles, Deborah E. Ortiz 2012 Scripps College

The Association Between Emotional Intelligence And Sexual Risk Behavior Among Undergraduate College Students In The Greater Los Angeles, Deborah E. Ortiz

Scripps Senior Theses

Sexual risk behaviors pose a major public health problem. However, sufficient research has not been done on the relationship between health risk behaviors and emotional intelligence. The purpose of this study was to examine the relationship between emotional intelligence, and sexual, smoking, and alcohol behavior among young adults. As well as explore the relationship between health risk behaviors. Emotional intelligence and sexual, alcohol, and smoking behavior of undergraduate college students from the greater Los Angeles area was assessed through an anonymous online questionnaire (n=80). There was no significant difference found in emotional intelligence between college students engaging in risk ...


Lyme Disease Prophylaxis: Idsa Guidelines, Kristine Cruz MD 2012 Fletcher Allen Health Care and the University of Vermont

Lyme Disease Prophylaxis: Idsa Guidelines, Kristine Cruz Md

Family Medicine Scholarly Works

Clinical Question: When should patients be given antibiotics for lyme prophylaxis after a tick bite?

Bottom Line Answer: To provide antibiotic prophylaxis for Lyme disease ALL of these criteria should be met:

  • Tick identified as an adult or nymphal deer tick
  • Attached for > or = 36 hours (by engorgement or time of exposure)
  • Treatment started within 72 hours of tick removal
  • Local rate of infection of ticks with B. Bourgdorferi >=20% (assumed in Vermont)
  • Doxyclycline is not contraindicated


Signal Transducer And Activator Of Transcription-5 Mediates Neuronal Apoptosis Induced By Inhibition Of Rac Gtpase Activity., Trisha R Stankiewicz, F Alexandra Loucks, Emily K Schroeder, Marja T Nevalainen, Kenneth L Tyler, Klaus Aktories, Ron J Bouchard, Daniel A Linseman 2012 University of Denver

Signal Transducer And Activator Of Transcription-5 Mediates Neuronal Apoptosis Induced By Inhibition Of Rac Gtpase Activity., Trisha R Stankiewicz, F Alexandra Loucks, Emily K Schroeder, Marja T Nevalainen, Kenneth L Tyler, Klaus Aktories, Ron J Bouchard, Daniel A Linseman

Department of Cancer Biology Faculty Papers

In several neuronal cell types, the small GTPase Rac is essential for survival. We have shown previously that the Rho family GTPase inhibitor Clostridium difficile toxin B (ToxB) induces apoptosis in primary rat cerebellar granule neurons (CGNs) principally via inhibition of Rac GTPase function. In the present study, incubation with ToxB activated a proapoptotic Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway, and a pan-JAK inhibitor protected CGNs from Rac inhibition. STAT1 expression was induced by ToxB; however, CGNs from STAT1 knock-out mice succumbed to ToxB-induced apoptosis as readily as wild-type CGNs. STAT3 displayed enhanced tyrosine phosphorylation ...


The Effects Of Xanthigen Supplementation On Body Weight, Resting Energy Expenditure, And Body Composition In An Obese Population, Lisa Knecht 2012 The University of Southern Mississippi

The Effects Of Xanthigen Supplementation On Body Weight, Resting Energy Expenditure, And Body Composition In An Obese Population, Lisa Knecht

Honors Theses

Since obesity is a significant problem that is facing the American people, there has been great interest in trying to develop a successful health supplement to help counteract the effects of obesity. Xanthigen is a new supplement composed of brown seaweed extract and pomegranate seed oil and is theorized to increase resting energy expenditure and decrease BMI and body fat. This study involved a 16‐week supplementation protocol to examine the effects of Xanthigen supplementation on an obese population in the Mississippi area. Testing of resting energy expenditure, BMI, and body fat percentage took place every four weeks for 16 ...


Knowledge And Attitudes Regarding The Human Papillomavirus And Hpv Vaccine Among College Students: A Gender Comparison Study, Kristen O'Flarity 2012 The University of Southern Mississippi

Knowledge And Attitudes Regarding The Human Papillomavirus And Hpv Vaccine Among College Students: A Gender Comparison Study, Kristen O'Flarity

Honors Theses

Objective: Both young men and women should obtain the human papillomavirus (HPV) vaccine in order to reach its intended public health benefits. Because men are behind in this vaccination campaign, this study compared knowledge and attitudes regarding HPV and the vaccine among college-aged men and women in order to improve vaccination strategies among this at-risk population.

Methods: A convenience sample of 95 university students, 40 men and 55 women, ages 18 to 26 (mean age of 20.2) completed self-administered pencil-and-paper questionnaires with approximately 40 questions that assessed the desired variables. Knowledge was measured through multiple choice and true/false ...


Barriers And Motivators For Influenza Vaccination Compliance Among Healthcare, Shelby Rogers 2012 The University of Southern Mississippi

Barriers And Motivators For Influenza Vaccination Compliance Among Healthcare, Shelby Rogers

Honors Theses

The influenza vaccine is a topic of much debate and concern throughout the healthcare profession. This vaccination has been shown to drastically reduce the number of nosocomial infections of the flu among hospitalized patients. While many healthcare professionals are aware of the benefits of obtaining the influenza vaccination, many remain noncompliant to actually getting vaccinated. This research will use a form of evidence-based practice known as an integrative review of literature in order to determine the course of nursing action to implement regarding influenza vaccination that will best increase the rates of its compliance among health professionals. A number of ...


Obesity Trends In Head Start Preschoolers, Anna Sanders 2012 The University of Southern Mississippi

Obesity Trends In Head Start Preschoolers, Anna Sanders

Honors Theses

The purpose of this natural comparative study is to see if changes in diet, education, and activity made in a South Mississippi Head Start (HS) preschool from Fall 2007 through Fall 2010 made any changes in the Body Mass Index (BMI) trends in two cohorts of low-income African American 3-year-olds. Cohort 1 BMI trends were measured in Fall 2006 and Spring 2007, before major HS changes in diet, education and activity were made (pre-treatment), and Cohort 2 was measured in Fall 2010 and Spring 2011, after major changes were made (post-treatment).


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