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Attention To Memory And The Environment: Functional Specialization And Dynamic Competition In Human Posterior Parietal Cortex, Carlo Sestieri, Gordon L. Shulman, Maurizio Corbetta 2010 Washington University School of Medicine in St. Louis

Attention To Memory And The Environment: Functional Specialization And Dynamic Competition In Human Posterior Parietal Cortex, Carlo Sestieri, Gordon L. Shulman, Maurizio Corbetta

Open Access Publications

No abstract provided.


Activation Of Metabotropic Glutamate Receptor 5 In The Amygdala Modulates Pain-Like Behavior, Benedict J. Kolber, Michael C. Montana, Yarimar Carrasquillo, Jian Xu, Stephen F. Heinemann, Louis J. Muglia, Robert W. Gereau IV 2010 Washington University School of Medicine in St. Louis

Activation Of Metabotropic Glutamate Receptor 5 In The Amygdala Modulates Pain-Like Behavior, Benedict J. Kolber, Michael C. Montana, Yarimar Carrasquillo, Jian Xu, Stephen F. Heinemann, Louis J. Muglia, Robert W. Gereau Iv

Open Access Publications

No abstract provided.


A Surface-Based Analysis Of Hemispheric Asymmetries And Folding Of Cerebral Cortex In Term-Born Human Infants, Jason Hill, Donna Dierker, Jeffrey Neil, Terrie Inder, Andrew Knutsen, John Harwell, Timothy Coalson, David Van Essen 2010 Washington University School of Medicine in St. Louis

A Surface-Based Analysis Of Hemispheric Asymmetries And Folding Of Cerebral Cortex In Term-Born Human Infants, Jason Hill, Donna Dierker, Jeffrey Neil, Terrie Inder, Andrew Knutsen, John Harwell, Timothy Coalson, David Van Essen

Open Access Publications

No abstract provided.


Defective Camp Generation Underlies The Sensitivity Of Cns Neurons To Neurofibromatosis-1 Heterozygosity, Jacquelyn A. Brown, Scott M. Gianino, David H. Gutmann 2010 Washington University School of Medicine in St. Louis

Defective Camp Generation Underlies The Sensitivity Of Cns Neurons To Neurofibromatosis-1 Heterozygosity, Jacquelyn A. Brown, Scott M. Gianino, David H. Gutmann

Open Access Publications

No abstract provided.


Gamma-Secretase Composed Of Ps1/Pen2/Aph1a Can Cleave Notch And Amyloid Precursor Protein In The Absence Of Nicastrin, Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, Raphael Kopan 2010 Washington University School of Medicine in St. Louis

Gamma-Secretase Composed Of Ps1/Pen2/Aph1a Can Cleave Notch And Amyloid Precursor Protein In The Absence Of Nicastrin, Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, Raphael Kopan

Open Access Publications

No abstract provided.


Prospects And Pits On The Path Of Biomimetics: The Case Of Tooth Enamel, Vuk Uskoković 2010 Chapman University

Prospects And Pits On The Path Of Biomimetics: The Case Of Tooth Enamel, Vuk Uskoković

Pharmacy Faculty Articles and Research

This review presents a discourse on challenges in understanding and imitating the process of amelogenesis in vitro on the molecular scale. In light of the analysis of imitation of the growth of dental enamel, it also impends on the prospects and potential drawbacks of the biomimetic approach in general. As the formation of enamel proceeds with the protein matrix guiding the crystal growth, while at the same time conducting its own degradation and removal, it is argued that three aspects of amelogenesis need to be induced in parallel: a) crystal growth; b) protein assembly; c) proteolytic degradation. A particular emphasis ...


Catalytic Function Of Pla2g6 Is Impaired By Mutations Associated With Infantile Neuroaxonal Dystrophy But Not Dystonia-Parkinsonism, Laura A. Engel, Zheng Jing, Daniel E. O’Brien, Mengyang Sun, Paul T. Kotzbauer 2010 Washington University School of Medicine in St. Louis

Catalytic Function Of Pla2g6 Is Impaired By Mutations Associated With Infantile Neuroaxonal Dystrophy But Not Dystonia-Parkinsonism, Laura A. Engel, Zheng Jing, Daniel E. O’Brien, Mengyang Sun, Paul T. Kotzbauer

Open Access Publications

No abstract provided.


Dkk1 Stabilizes Wnt Co-Receptor Lrp6: Implication For Wnt Ligand-Induced Lrp6 Down-Regulation, Yonghe Li, Wenyan Lu, Taj D. King, Chia-Chen Liu, Gautam N. Bijur, Guojun Bu 2010 Washington University School of Medicine in St. Louis

Dkk1 Stabilizes Wnt Co-Receptor Lrp6: Implication For Wnt Ligand-Induced Lrp6 Down-Regulation, Yonghe Li, Wenyan Lu, Taj D. King, Chia-Chen Liu, Gautam N. Bijur, Guojun Bu

Open Access Publications

No abstract provided.


Low-Density Lipoprotein Receptor-Related Protein 1 (Lrp1) Mediates Neuronal Abeta42 Uptake And Lysosomal Trafficking, Rodrigo A. Fuentealba, Qiang Liu, Juan Zhang, Takahisa Kanekiyo, Xiaoyan Hu, Jin-Moo Lee, Mary Jo LaDu, Guojun Bu 2010 Washington University School of Medicine in St. Louis

Low-Density Lipoprotein Receptor-Related Protein 1 (Lrp1) Mediates Neuronal Abeta42 Uptake And Lysosomal Trafficking, Rodrigo A. Fuentealba, Qiang Liu, Juan Zhang, Takahisa Kanekiyo, Xiaoyan Hu, Jin-Moo Lee, Mary Jo Ladu, Guojun Bu

Open Access Publications

No abstract provided.


Human Cytomegalovirus Protein Pul117 Targets The Mini-Chromosome Maintenance Complex And Suppresses Cellular Dna Synthesis, Zhikang Qian, Van Leung-Pineda, Baoqin Xuan, Helen Piwnica-Worms, Dong Yu 2010 Washington University School of Medicine in St. Louis

Human Cytomegalovirus Protein Pul117 Targets The Mini-Chromosome Maintenance Complex And Suppresses Cellular Dna Synthesis, Zhikang Qian, Van Leung-Pineda, Baoqin Xuan, Helen Piwnica-Worms, Dong Yu

Open Access Publications

No abstract provided.


Promoters, Enhancers, And Transcription Target Rag1 Binding During V(D)J Recombination, Yanhong Ji, Alicia J. Little, Joydeep K. Banerjee, Bingtao Hao, Eugene M. Oltz, Michael S. Krangel, David G. Schatz 2010 Yale University

Promoters, Enhancers, And Transcription Target Rag1 Binding During V(D)J Recombination, Yanhong Ji, Alicia J. Little, Joydeep K. Banerjee, Bingtao Hao, Eugene M. Oltz, Michael S. Krangel, David G. Schatz

Open Access Publications

No abstract provided.


Sliding Set-Points Of Immune Responses For Therapy Of Autoimmunity, Chyi-Song Hsieh, Jhoanne Lynne Bautista 2010 Washington University School of Medicine in St. Louis

Sliding Set-Points Of Immune Responses For Therapy Of Autoimmunity, Chyi-Song Hsieh, Jhoanne Lynne Bautista

Open Access Publications

No abstract provided.


Oral Contraceptives: The Risks, Benefits, And Dilemmas, Courtney S. West 2010 Liberty University

Oral Contraceptives: The Risks, Benefits, And Dilemmas, Courtney S. West

Senior Honors Theses

Millions of women have chosen to use oral contraceptives for various reasons. However, the question must be raised as to the awareness level of the risks and benefits associated with the use of oral contraceptives. Numerous studies have been performed to establish the effects of oral contraceptives. This thesis examines these studies to consolidate the most current findings.

In order to present these studies effectively, this thesis will begin by briefly summarizing the menstrual cycle and how the use of oral contraceptives affects menstruation. Following this, a review of the risks, benefits, and ethical dilemmas will be presented. Utilizing the ...


Applicability And Integration Of Plasma Sprayed Hydroxyapatite Coated Ao Cortical Bone Screws In Equine Bone, Timm Gudehus 2010 Louisiana State University and Agricultural and Mechanical College

Applicability And Integration Of Plasma Sprayed Hydroxyapatite Coated Ao Cortical Bone Screws In Equine Bone, Timm Gudehus

LSU Master's Theses

To compare insertion temperatures and torques of Hydroxyapatite (HA) coated and uncoated 5.5 mm AO cortical screws in equine third metatarsal bones (MTIII) in vitro, and to compare insertion and extraction torques of HA coated and uncoated screws after 4, 8, 12 and 16 weeks of healing in equine third metacarpal bones (MCIII) in vivo. No significant temperature differences were recorded in cadaveric bones for AO and HA coated screws. Insertion torques were significantly higher for HA coated implants compared to uncoated screws. In vivo, the AO screws lost 50% of their initial stability within 4 weeks of healing ...


Implementing Evidence-Based Practice In Taiwanese Nursing Homes Attitudes And Perceived Barriers And Facilitators, Hui Chen Chang, Cherry Russell, Mairwen Jones 2010 Yuanpei University

Implementing Evidence-Based Practice In Taiwanese Nursing Homes Attitudes And Perceived Barriers And Facilitators, Hui Chen Chang, Cherry Russell, Mairwen Jones

Faculty of Science, Medicine and Health - Papers

To date, there is a paucity of research investigating nurses' perceptions of evidence-based practice (EBP) in nursing homes, especially in non-Western countries. This descriptive, quantitative study investigated attitudes toward and perceived barriers and facilitators to research utilization among 89 Taiwanese RNs. The majority of nurses expressed positive attitudes toward research and EBP. The most frequently cited barriers were related to insufficient authority to change practice, difficulty understanding statistical analyses, and a perceived isolation from knowledgeable colleagues with whom to discuss the research. EBP facilitators included improved access to computers and Internet facilities in the workplace, more effective research training, and ...


Low Back Pain In Schoolgirl Rowers : Prevalence, Bio-Psycho-Social Factors And Prevention, Debra Perich 2010 Edith Cowan University

Low Back Pain In Schoolgirl Rowers : Prevalence, Bio-Psycho-Social Factors And Prevention, Debra Perich

Theses: Doctorates and Masters

Rowing is one of the largest participant sports on the Independent Girls‟ Schools Sporting Association (IGSSA) in Western Australia with approximately 400 participants competing every year. Rowing is an extra-curricular sport offered to girls 14 years of age and above, with these girls competing and training in both sweep and scull boats. Whilst the benefits of regular physical activity and exercise are well known, musculoskeletal problems have been documented in rowing. In particular, clinical evidence and previous research suggests that low back pain (LBP) is common in rowers. Adolescents who suffer from LBP are at an increased risk of recurrent ...


Utilising A Combined Exercise And Counselling Program To Examine The Relationship Between Emotional Self-Efficacy And Physiological Improvements In Breast Cancer Survivors, Jena K. Buchan 2010 University of Notre Dame Australia

Utilising A Combined Exercise And Counselling Program To Examine The Relationship Between Emotional Self-Efficacy And Physiological Improvements In Breast Cancer Survivors, Jena K. Buchan

Theses

Breast cancer diagnosis in women has increased in recent years, though medical progress has helped more patients become survivors rather than victims. With cancer diagnosis and treatment, however, comes a host of psychological and physical side effects that must be addressed. Research has found exercise and counselling may decrease the detrimental effects of breast cancer, but programs have typically utilised these modalities separately. As psychosocial issues appear correlated with physical health, it is imperative to examine the mind-body connection and explore the benefits of a combination exercise and counselling program. One psychological variable of interest is emotional self-efficacy, which relates ...


Pubertal Trajectory And The Management Of Menstruation In Females With Rett Syndrome And Down Syndrome, Olivia Annelies Knight 2010 Edith Cowan University

Pubertal Trajectory And The Management Of Menstruation In Females With Rett Syndrome And Down Syndrome, Olivia Annelies Knight

Theses : Honours

Background: Puberty is a challenging transition for all young women and particularly so for those with an intellectual disability. Individuals with an intellectual disability often experience both cognitive and physical impairment and a wide range of comorbidities. This review explores research into the pubertal trajectory and the management of menstruation in two syndromes within intellectual disability. Rett syndrome which is a severe neurodevelopmental disorder and Down syndrome which is a chromosomal birth disorder. Aim: The purpose of this review was to identify research exploring pube1ial trajectory and menstrual management in females with Rett syndrome and Down syndrome and to identify ...


Carprofen-Induced Oxidative Stress In Mitochondria Of The Colonic Mucosa Of The Dog, Lynne A. Snow 2010 Louisiana State University and Agricultural and Mechanical College

Carprofen-Induced Oxidative Stress In Mitochondria Of The Colonic Mucosa Of The Dog, Lynne A. Snow

LSU Master's Theses

Objectives 1) To measure conductance and permeability of canine colonic mucosa exposed to increasing concentrations of carprofen. 2) To compare conductance and permeability of canine colonic mucosa exposed to carprofen or 2,4-dinitrophenol (DNP) and tempol blockade. Design In vitro randomized block design Animal 20 mixed breed dogs Methods Conductance, mannitol flux, and histology were evaluated in colonic mucosa mounted in Ussing chambers. Mucosa was first exposed to increasing concentrations of carprofen. Mucosa was then exposed to either carprofen (200 μg/ml) or DNP (0.25mM) +/- tempol (1mM) pretreatment. Conductance over time, mannitol fluxes, and frequency of histologic categories were ...


Investigation Of A Classroom-Based Reading Intervention Strategy For Older Elementary Students With Poor Decoding Skills, Shara Brinkley 2010 Louisiana State University and Agricultural and Mechanical College

Investigation Of A Classroom-Based Reading Intervention Strategy For Older Elementary Students With Poor Decoding Skills, Shara Brinkley

LSU Doctoral Dissertations

Using a response to intervention framework, this study investigates the efficacy of a classroom-based intervention for struggling readers with decoding deficits in the upper elementary grades. Twenty two students in the fourth and sixth grades from four classrooms in low-performing schools received either a short 20-minute intervention delivered by their teacher or access to the lessons for an equivalent amount of time but no teacher instruction. Using three orthographic patterns, the 24 lessons consisted of a series of ten minimally contrasted words differing by one letter. The students in the experimental group decoded the words using a visual alphabet (Phonic ...


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