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Calcinosis Circumscripta In The Antebrachiocarpal Joint Of A Horse, Ferenc Toth, James Schumacher, Shelley Newman 2009 Selected Works

Calcinosis Circumscripta In The Antebrachiocarpal Joint Of A Horse, Ferenc Toth, James Schumacher, Shelley Newman

Ferenc Toth

A 4-year-old, Spanish Mustang mare was evaluated because of a swelling on the dorsolateral aspect of its right carpus. The horse had no gait abnormalities. During radiographic examination of the carpus, a granular, radiopaque mass, approximately 3 cm in diameter, adjacent to the proximal row of carpal bones, was observed. The mineralised mass, which was located within the antebrachiocarpal joint, was removed through an arthrotomy with the horse anaesthetised. Histological features of the mass showed it to be overlain by partially denuded synovium, and included large deposits of mineral surrounded by multinucleated giant cells and separated by septa of mature ...


Legal Briefing: Informed Consent, Thaddeus Pope 2009 Widener University - Delaware Campus

Legal Briefing: Informed Consent, Thaddeus Pope

Thaddeus Mason Pope

This issue’s “Legal Briefing” column covers legal developments pertaining to informed consent. Not only has this topic been the subject of recent articles in this journal, but it also been the subject of numerous public and professional discussions over the past several months. Legal developments concerning informed consent can be usefully grouped into nine categories: (1) general disclosure standards in the clinical context, (2) shared decision making, (3) statutorily mandated abortion disclosures, (4) statutorily mandated end-of-life counseling, (5) other statutorily mandated subject-specific disclosures, (6) U.S. Food and Drug Administration (FDA) labeling and federal pre-emption of state informed consent ...


Canine Urate Urolithiasis, Joe Bartges 2009 University of Tennessee - Knoxville

Canine Urate Urolithiasis, Joe Bartges

Joe Bartges

No abstract provided.


Current Understanding And Pharmacological Management Of Suicide Behavior In Clinical Setting, Amresh Shrivastava 2009 The University of Western Ontario

Current Understanding And Pharmacological Management Of Suicide Behavior In Clinical Setting, Amresh Shrivastava

Amresh Srivastava

This presentation addresses these issues:
• Nature of problem in clinical settings
• Current understanding about suicide behavior (neurobiology)
• What can be done to deal with suicide in clinical settings
• Pharmacological management


Probabilistic Peak Calling And Controlling False Discovery Rate In Transcription Factor Binding Site Mapping From Chip-Seq, SHUO JIAO, Cheryl Bailey, Shunpu Zhang, Istvan Ladunga 2009 Fred Hutchinson Cancer Research Center

Probabilistic Peak Calling And Controlling False Discovery Rate In Transcription Factor Binding Site Mapping From Chip-Seq, Shuo Jiao, Cheryl Bailey, Shunpu Zhang, Istvan Ladunga

Shuo Jiao

No abstract provided.


Physical Rehabilitation Of The Canine Neurologic Patient., Marti Drum 2009 University of Tennessee, Knoxville

Physical Rehabilitation Of The Canine Neurologic Patient., Marti Drum

Marti G Drum

Rehabilitation therapy is a key component of recovery from neurologic disease. Each patient requires a rehabilitation protocol designed specifically for the patient's neurologic condition, owner expectations and level of participation, and expertise of the veterinary team. Initial therapy for nonambualtory patients may include standing exercises, range of motion, pain control, toe pinch exercise, aquatic exercise, and basic nursing care. Sling assisted walking with foot protection, cavaletti rails, and physioroll balancing are used commonly for ambulatory patients. As recovery progresses, stair climbing, carrying or pulling weights, resistance band walking, swimming against resistance, and exercises specific to the home environment are ...


Meta-Analysis For Surrogacy: Accelerated Failure Time Models And Semicompeting Risks Modelling, Debashis Ghosh, Jeremy Taylor, Daniel Sargent 2009 Penn State University

Meta-Analysis For Surrogacy: Accelerated Failure Time Models And Semicompeting Risks Modelling, Debashis Ghosh, Jeremy Taylor, Daniel Sargent

Debashis Ghosh

There has been great recent interest in the medical and statistical literature in the assessment and validation of surrogate endpoints as proxies for clinical endpoints in medical studies. More recently, authors have focused on using meta-analytical methods for quanti #12;cation of surrogacy. In this article, we extend existing procedures for analysis based on the accelerated failure time model to this setting. An advantage of this approach relative to proportional hazards model is that it allows for analysis in the semi-competing risks setting, where we constrain the surrogate endpoint to occur before the true endpoint. A novel principal components procedure ...


Healthcare Georgia Foundation, Economic Impact Of Health Disparities - School-Based Teledentistry To Address Oral Health Disparities In Georgia’S Rural Children: An Economic Analysis., Renee Hotchkiss, J. Yoon, A. Scott 2009 Selected Works

Healthcare Georgia Foundation, Economic Impact Of Health Disparities - School-Based Teledentistry To Address Oral Health Disparities In Georgia’S Rural Children: An Economic Analysis., Renee Hotchkiss, J. Yoon, A. Scott

Renee B. Hotchkiss

No abstract provided.


Targeting Obesity Among African Americans Through Nutrition, Fitness, And Faith: Designing And Testing A Community-Driven Pilot Program, Luvenia Cowart, Diana Biro, Timothy Wasserman, Ruth Stein, Lindsey Reider 2009 Syracuse University

Targeting Obesity Among African Americans Through Nutrition, Fitness, And Faith: Designing And Testing A Community-Driven Pilot Program, Luvenia Cowart, Diana Biro, Timothy Wasserman, Ruth Stein, Lindsey Reider

Luvenia W. Cowart

Obesity raises the risk for many chronic diseases and poor health outcomes. African Americans have the highest rates of excess weight in the nation, and standard weight management programs have not worked well with this population. The Genesis Health Project, a community-designed, culturally competent intervention to reduce obesity and promote healthy lifestyles, represents a successful partnership among Syracuse University, local Black churches, and several sponsors to empower families of color to adopt and sustain positive health practices across the lifespan. This article describes the Phase I design and pilot-testing of this demonstration project, and reports the results of the first-year ...


Discolored Urine, Joe Bartges 2009 University of Tennessee - Knoxville

Discolored Urine, Joe Bartges

Joe Bartges

No abstract provided.


The Topography And Geography Of U.S. Health Care Regulation, Thaddeus Pope 2009 Widener University - Delaware Campus

The Topography And Geography Of U.S. Health Care Regulation, Thaddeus Pope

Thaddeus Mason Pope

This is a book review of Health Care Regulation in America: Complexity, Confrontation, and Compromise by Robert I. Field (Oxford University Press, 2007).

On the front cover of Field’s new book, Health Care Regulation in America: Complexity, Confrontation, and Compromise, is a picture of a giant three-dimensional labyrinth. Rarely is cover art so perfectly appropriate. A maze is surely the image that best symbolizes the core objective of Field’s book: to provide readers a map and guidebook to the many interacting and overlapping private institutions and government agencies that regulate health care in America.

Like all primers, the ...


Helmke Library Guide To Complementary And Alternative Medicine Resources, Shannon Johnson 2009 Indiana University Purdue University Fort Wayne

Helmke Library Guide To Complementary And Alternative Medicine Resources, Shannon Johnson

Shannon F Johnson

This guide is designed for use by IPFW students, staff, and faculty looking for information on complementary and alternative health topics.


Diagnostic Procedures For The Private Practice, Joe Bartges 2009 University of Tennessee - Knoxville

Diagnostic Procedures For The Private Practice, Joe Bartges

Joe Bartges

No abstract provided.


Ellagic Acid, Phenolic Acids, And Flavonoids In Malaysian Honey Extracts Demonstrate In Vitro Anti-Inflammatory Activity, Mustafa Ali Mohd, Mohd Rais Mustafa 2009 University of Malaya

Ellagic Acid, Phenolic Acids, And Flavonoids In Malaysian Honey Extracts Demonstrate In Vitro Anti-Inflammatory Activity, Mustafa Ali Mohd, Mohd Rais Mustafa

Mustafa Ali Mohd

Natural honey has been used in traditional medicine of different cultures throughout the world. This study looked into the extraction of Malaysian honey and the evaluation of the anti-inflammatory activity of these extracts. It was hypothesized that honey extracts contain varying amounts of phenolic compounds and that they possess different in vitro anti-inflammatory activities. Honey extracts were analyzed using liquid chromatography-mass spectrometry to identify and compare phenolic compounds, whereas high-performance liquid chromatography was used for their quantification. Subsequently, honey methanol extract (HME) and honey ethyl acetate extract (HEAE) were tested in vitro for their effect on nitric oxide production in ...


Serial Evaluation Of Physiologic, Pathological, And Behavioral Changes Related To Disease Progression Of Experimentally Induced Mannheimia Haemolytica Pneumonia In Postweaned Calves., G. Hanzlicek, B. White, D. Mosier, D. Renter, David Anderson 2009 Kansas State University

Serial Evaluation Of Physiologic, Pathological, And Behavioral Changes Related To Disease Progression Of Experimentally Induced Mannheimia Haemolytica Pneumonia In Postweaned Calves., G. Hanzlicek, B. White, D. Mosier, D. Renter, David Anderson

David Edgar Anderson, DVM, MS, DACVS

OBJECTIVE: To determine the usefulness of physiologic, behavioral, and pathological changes as objective indicators of early respiratory disease in calves with Mannheimia haemolytica pneumonia. ANIMALS: 14 crossbred beef steers. PROCEDURES: Disease was experimentally induced in healthy calves through endoscopic pulmonary inoculation of M haemolytica. Calves were necropsied on days 1, 2, 3, 5, 7, and 9 after inoculation. Physical examination variables (rectal temperature, heart rate, and respiration characteristics), clinical illness score, and degree of activity were assessed 3 times daily beginning 4 days prior to inoculation and continuing throughout the study. Twice before inoculation and on days 1, 2, 3 ...


Impact Of Role Discrepancies On Caregiver Burden Among Spouses, Marie Savundranayagam, R. Montgomery 2009 Western University

Impact Of Role Discrepancies On Caregiver Burden Among Spouses, Marie Savundranayagam, R. Montgomery

Marie Y Savundranayagam

Using caregiver identity theory, the authors investigated whether role discrepancies mediated the relationships between illness-related stressors (activities of daily living [ADLs] limitations and problem behaviors) and burden (stress, relationship, and objective burden) for spouse caregivers. Participants completed measures of identity standards for spouse and caregiver roles and behaviors, burden, assistance with ADLs, and problem behaviors. Structural equation modeling analyses revealed that role discrepancies completely mediated the relationships between ADLs and stress and relationship burden. Although role discrepancies mediated the relationships between problem behaviors and all forms of burden, there were direct relationships between problem behaviors and burden. Finally, participants who ...


Use Of Propentofylline In Feline Bronchial Disease: Prospective, Randomized, Positive-Controlled Study, U Stursberg, I Zenker, Silke Hecht, K Hartmann, B Schulz 2009 University of Tennessee - Knoxville

Use Of Propentofylline In Feline Bronchial Disease: Prospective, Randomized, Positive-Controlled Study, U Stursberg, I Zenker, Silke Hecht, K Hartmann, B Schulz

Silke Hecht

Propentofylline is a methylxanthine derivative with bronchodilating actions similar to those of theophylline. Nineteen cats with bronchial disease were enrolled in this study. All cats received a low dose of prednisolone; 10 of the cats additionally received propentofylline. Propentofylline-treated cats significantly improved in their auscultation scores, respiratory pattern scores, and radiological bronchial markings score over the observation period, and they coughed less and slept less at the end of the study. No significant changes were noted in the control group. This study provides evidence that a combination therapy with prednisolone and propentofylline in cats with bronchial disease might be superior ...


Immunomodulatory Effects Of Opioids., Adesola Odunayo, J. Dodam, Marie Kerl, A. DeClue 2009 Selected Works

Immunomodulatory Effects Of Opioids., Adesola Odunayo, J. Dodam, Marie Kerl, A. Declue

Adesola Odunayo, DVM, MS, DACVECC

OBJECTIVE: To review the immunomodulatory effects of opioids. DATA SOURCES: Original research publications and review articles using the PubMed search engine with the following keywords--opioids, morphine, immuomodulation, and immunosuppression. VETERINARY AND HUMAN DATA SYNTHESIS: Opioids have been shown to modulate the immune system in animal models by affecting both the acquired and innate arms of the immune system. Natural killer cell activity, T-cell proliferation, antibody production, phagocytic cell function, and cytokine production have all been shown to be affected by opioids. Many of these effects are reversed by opioid antagonists. Opioids have also been shown to induce sepsis in laboratory ...


Discrete Nonparametric Algorithms For Outlier Detection With Genomic Data, Debashis Ghosh 2009 Penn State University

Discrete Nonparametric Algorithms For Outlier Detection With Genomic Data, Debashis Ghosh

Debashis Ghosh

In high-throughput studies involving genetic data such as from gene expression mi- croarrays, di#11;erential expression analysis between two or more experimental conditions has been a very common analytical task. Much of the resulting literature on multiple comparisons has paid relatively little attention to the choice of test statistic. In this article, we focus on the issue of choice of test statistic based on a special pattern of di#11;erential expression. The approach here is based on recasting multiple comparisons procedures for assessing outlying expression values. A major complication is that the resulting p-values are discrete; some theoretical ...


The Effect Of Salvage Therapy On Survival In A Longitudinal Study With Treatment By Indication, Edward Kennedy, Jeremy Taylor, Douglas Schaubel, Scott Williams 2009 University of Pennsylvania

The Effect Of Salvage Therapy On Survival In A Longitudinal Study With Treatment By Indication, Edward Kennedy, Jeremy Taylor, Douglas Schaubel, Scott Williams

Edward H. Kennedy

We consider using observational data to estimate the effect of a treatment on disease recurrence, when the decision to initiate treatment is based on longitudinal factors associated with the risk of recurrence. The effect of salvage androgen deprivation therapy (SADT) on the risk of recurrence of prostate cancer is inadequately described by the existing literature. Furthermore, standard Cox regression yields biased estimates of the effect of SADT, since it is necessary to adjust for prostate-specific antigen (PSA), which is a time-dependent confounder and an intermediate variable. In this paper, we describe and compare two methods which appropriately adjust for PSA ...


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