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Jefferson Alumni Bulletin – Volume 59, Number 2, Spring 2010, 2010 Thomas Jefferson University

Jefferson Alumni Bulletin – Volume 59, Number 2, Spring 2010

Jefferson Medical College Alumni Bulletin

Jefferson Alumni Bulletin – Volume 59, Number 2, Spring 2010

Dean's Message, page 2

Findings: Researchers Decode Powerful Tumor Suppressor, page 4

Jefferson Physicians Respond to Haiti Earthquake, page 6

Student Blog: Exploring Health Care in Uganda, page 10

JHN Physicians Use Robotic System to Examine Patients from Afar, page 13

Crime in the Age of Science: 19th Century Body Snatching, page 14

Faculty Profile: Edouard Trabulsi: Easing the Burden on Cancer Patients, page 18

On Campus, page 20

Class Notes: George Valko, MD ’86: Alumni Association’s New President, page 22

In Memoriam, page 27

By the Numbers, page ...


Sports Holdings In The Southeastern Conference University Libraries: Football As A Case Study, William F. Meehan III, Margaret A. Swanson, Catherine O. Yates, Emily N. Decker 2010 Valdosta State University

Sports Holdings In The Southeastern Conference University Libraries: Football As A Case Study, William F. Meehan Iii, Margaret A. Swanson, Catherine O. Yates, Emily N. Decker

The Southeastern Librarian

Of the twelve National Collegiate Athletic Association’s (NCAA) Division I Football Bowl Subdivision conferences, the Southeastern Conference (SEC) has attained prominence. But how do the SEC’s university libraries fare when evaluated for their football holdings? While university libraries develop their collections mainly to support research and teaching functions, according to accepted collection development practice, the extent to which sports of local importance are represented in their collections is a subject given little attention in the professional literature.

In order to help close the gap, this study evaluates the football holdings of the 12 SEC university library systems using ...


A Novel Collagen Scaffold Supports Human Osteogenesis--Applications For Bone Tissue Engineering., Michael B. Keogh, Fergal J. O'Brien, Jacqueline Daly 2010 Royal College of Surgeons in Ireland

A Novel Collagen Scaffold Supports Human Osteogenesis--Applications For Bone Tissue Engineering., Michael B. Keogh, Fergal J. O'Brien, Jacqueline Daly

Anatomy Articles

Collagen glycosaminoglycan (CG) scaffolds have been clinically approved as an application for skin regeneration. The goal of this study has been to examine whether a CG scaffold is a suitable biomaterial for generating human bone tissue. Specifically, we have asked the following questions: (1) can the scaffold support human osteoblast growth and differentiation and (2) how might recombinant human transforming growth factor-beta (TGF-beta(1)) enhance long-term in vitro bone formation? We show human osteoblast attachment, infiltration and uniform distribution throughout the construct, reaching the centre within 14 days of seeding. We have identified the fully differentiated osteoblast phenotype categorised by ...


Interleukin-8, Interleukin-1Β, And Interferon-Γ Levels Are Linked To Prrs Virus Clearance, Joan K. Lunney, Eric Fritz, James M. Reecy, Daniel Kuhar, Elizabeth Prucnal, Ramon Molina, Jane Christopher-Hennings, Jeffrey J. Zimmerman, Raymond Rowland 2010 United States Department of Agriculture

Interleukin-8, Interleukin-1Β, And Interferon-Γ Levels Are Linked To Prrs Virus Clearance, Joan K. Lunney, Eric Fritz, James M. Reecy, Daniel Kuhar, Elizabeth Prucnal, Ramon Molina, Jane Christopher-Hennings, Jeffrey J. Zimmerman, Raymond Rowland

Animal Science Publications

Infection with porcine reproductive and respiratory syndrome virus (PRRSV) results in a weak antiviral immune response that leads to a persistent infection in a subset of pigs. We investigated the intensity and timing of the early cytokine responses to PRRSV infection to determine their utility as a predictor of persistence. As part of the “Big Pig” project, we evaluated cytokine gene expression in lymphoid tissues collected from pigs for up 202 days post-infection (dpi); serum samples were collected biweekly. Cytokine mRNA levels were compared between pigs that cleared the viral infection from serum and tissues (non-persistent [NP] pigs) to those ...


The Relationship Between Workforce Flexibility And The Costs And Outcomes Of Older Peoples Services, Susan Nancarrow, Pamela Enderby, Anna Moran, Simon Dixon, Stuart Parker, Michael Bradburn, Caroline Mitchell 2010 Southern Cross University

The Relationship Between Workforce Flexibility And The Costs And Outcomes Of Older Peoples Services, Susan Nancarrow, Pamela Enderby, Anna Moran, Simon Dixon, Stuart Parker, Michael Bradburn, Caroline Mitchell

Susan Nancarrow

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Bracket Bond Strength Effects Of Incorporation Of Novamin Into An Orthodontic Bonding Resin, Jeffrey Waterhouse 2010 Marquette University

Bracket Bond Strength Effects Of Incorporation Of Novamin Into An Orthodontic Bonding Resin, Jeffrey Waterhouse

Master's Theses (2009 -)

Despite advances in caries research and the development of protective mechanisms and materials, orthodontic white spot decalcification remains a significant problem. Increased plaque buildup around orthodontic appliances, combined with inadequate hygiene and a susceptible patient, can lead to unesthetic demineralized lesions in enamel.

Relatively new to the arena of caries prevention, NovaMin, a bioactive glass, has shown some promise in areas of remineralization of early lesions, protection against acidic challenge, and has demonstrated antiplaque properties. This study explored a new application of the material, incorporation into an orthodontic bonding composite resin. Objectives of the study were: to determine if the ...


Application Of Mechanical Vibration To Modulate Orthodontic Tooth Movement (Otm) In Mice, Andrew Rummel 2010 Marquette University

Application Of Mechanical Vibration To Modulate Orthodontic Tooth Movement (Otm) In Mice, Andrew Rummel

Master's Theses (2009 -)

Purpose: The purpose of this study was to use micro CT to evaluate the effect of mechanical vibration on orthodontic tooth movement (OTM) in mice. Materials and Methods: Thirty-six mice (C57BL/6, 20 weeks old, male) were randomly divided into four groups: spring/vibration (SV), spring only (S), vibration only (V), control (C). A nickel-titanium (NiTi) spring was fabricated and inserted bilaterally between the maxillary 1st molars, delivering an initial force of 20 grams. From day 0, mechanical vibration (4Hz frequency, 20micron displacement, 5 min per session duration) was applied to the left maxillary 1st molar every three days for ...


From Blood Pressure To Physical Disability: The Role Of Cognition, Merrill F. Elias, Gregory A. Dore, Adam Davey, Michael A. Robbins, Penelope K. Elias 2010 University of Maine - Main

From Blood Pressure To Physical Disability: The Role Of Cognition, Merrill F. Elias, Gregory A. Dore, Adam Davey, Michael A. Robbins, Penelope K. Elias

Maine-Syracuse Longitudinal Papers

We examined the hypothesis that lowered cognitive performance plays a role in the relation between elevated blood pressure and physical disability in performing basic physical tasks. A community-based sample (N = 1025) free from stroke and dementia (mean age: 61.1 years; SD: 13.0 years; 59.8% women) was used. Using path analysis, systolic and diastolic blood pressures (predictor variable) measured over multiple longitudinal examinations were averaged and related to multiple measures of cognition (intermediate variable) and physical ability (PA; outcome variable) measured at wave 6 of the Maine-Syracuse Study. PA was indexed by time required to execute standing, walking ...


Percutaneous Coronary Intervention In Unprotected Left Main Coronary Artery Disease, Hafeez Ahmed, Javed Majid Tai, Sajid H. Dhakam 2010 Aga Khan University

Percutaneous Coronary Intervention In Unprotected Left Main Coronary Artery Disease, Hafeez Ahmed, Javed Majid Tai, Sajid H. Dhakam

Section of Cardiology

Percutaneous coronary intervention for unprotected left main coronary artery disease is potentially an important intervention in surgically unstable patients. A detailed review of medical record and visual analysis of coronary angiography and PCI procedure was undertaken. The study was conducted at the Aga Khan University Hospital, from January 2003 to December 2007. Patients included in the study had unprotected > 70% left main stenosis with ongoing ischemia, considered unsuitable for surgical revascularization. A total of 9 patients were included with a mean age of 70.1 years. Six patients had cardiogenic shock. Eight patients had bifurcation lesion. Simultaneous kissing stenting technique ...


Living Positively: An Inside Look At Hiv Counseling And Testing In Uganda, Lindsay Bergmann 2010 University of New Hampshire

Living Positively: An Inside Look At Hiv Counseling And Testing In Uganda, Lindsay Bergmann

Inquiry Journal 2010

No abstract provided.


Gene Harkless, Associate Professor Of Nursing, Jennifer Lee 2010 University of New Hampshire

Gene Harkless, Associate Professor Of Nursing, Jennifer Lee

Inquiry Journal 2010

No abstract provided.


The Many Faces Of Health: Dialogue And Research At The University Of New Hampshire, Emily D. Robbins 2010 University of New Hampshire

The Many Faces Of Health: Dialogue And Research At The University Of New Hampshire, Emily D. Robbins

Inquiry Journal 2010

No abstract provided.


Walk On, Australia: An Exceptional Approach To Spinal Cord Injury, Amanda Russell 2010 University of New Hampshire

Walk On, Australia: An Exceptional Approach To Spinal Cord Injury, Amanda Russell

Inquiry Journal 2010

No abstract provided.


Addressing Cultural Barriers In Australia’S Acute Care System: Problems The United States Can Learn From, Allison Reilly 2010 University of New Hampshire

Addressing Cultural Barriers In Australia’S Acute Care System: Problems The United States Can Learn From, Allison Reilly

Inquiry Journal 2010

No abstract provided.


Mind-Body Medicine A Hundred Years Ago: An Eclectic, New England Approach To Psychotherapy, Courtney Stevens 2010 University of New Hampshire

Mind-Body Medicine A Hundred Years Ago: An Eclectic, New England Approach To Psychotherapy, Courtney Stevens

Inquiry Journal 2010

No abstract provided.


Capsaicin Displays Anti-Proliferative Activity Against Human Small Cell Lung Cancer In Cell Culture And Nude Mice Models Via The E2f Pathway, Kathleen C. Brown, Theodore R. Witte, W. Elaine Hardman, Haitao Luo, Yi C. Chen, A. Betts Carpenter, Jamie K. Lau, Piyali Dasgupta 2010 Marshall University

Capsaicin Displays Anti-Proliferative Activity Against Human Small Cell Lung Cancer In Cell Culture And Nude Mice Models Via The E2f Pathway, Kathleen C. Brown, Theodore R. Witte, W. Elaine Hardman, Haitao Luo, Yi C. Chen, A. Betts Carpenter, Jamie K. Lau, Piyali Dasgupta

Biochemistry and Microbiology

Background: Small cell lung cancer (SCLC) is characterized by rapid progression and low survival rates. Therefore, novel therapeutic agents are urgently needed for this disease. Capsaicin, the active ingredient of chilli peppers, displays antiproliferative activity in prostate and epidermoid cancer in vitro. However, the anti-proliferative activity of capsaicin has not been studied in human SCLCs. The present manuscript fills this void of knowledge and explores the anti-proliferative effect of capsaicin in SCLC in vitro and in vivo.

Methodology/Principal Findings: BrdU assays and PCNA ELISAs showed that capsaicin displays robust anti-proliferative activity in four human SCLC cell lines. Furthermore, capsaicin ...


Light-Activation Influence On The Thermal Analysis Of A Resin-Modified Glass-Ionomer, Raksha Srinivas 2010 Marquette University

Light-Activation Influence On The Thermal Analysis Of A Resin-Modified Glass-Ionomer, Raksha Srinivas

Master's Theses (2009 -)

The acid-base and light polymerization reactions in resin modified glass ionomers (RMGI) have been shown to compete and possibly inhibit one another during early RMGI development. Earlier beginning times of light polymerization initiation may limit the acid-base reaction and if time allowed for the acid-base components to react is increased, the extent of light cure reaction may be lesser. The thermal behavior of a commercially available RMGI was investigated in relation to a light initiation regimen using a differential scanning calorimeter (DSC). The relationship between delay in light initiation or no light initiation and the resultant set matrix of the ...


Bondable Lingual Spur Therapy To Treat Anterior Open Bite, Elissa Joy McRae 2010 Marquette University

Bondable Lingual Spur Therapy To Treat Anterior Open Bite, Elissa Joy Mcrae

Master's Theses (2009 -)

The purpose of this study was to evaluate the effect of bondable lingual tongue spurs (BLTS; Tongue Tamers®, Ortho Technology, Tampa, FL) on measures of overbite and incisor position in a sample of anterior open bite subjects who had either a digit-sucking habit or an anterior tongue posture problem. Patient acceptance of the spurs was also evaluated. BLTS were placed on all maxillary and mandibular incisors of 12 subjects (mean age 13.9 years) with anterior open bite. Dental casts and lateral cephalometric radiographs were taken pre-treatment (T1) and after 6 months of lingual spur treatment alone (T2). Overbite and ...


African American Women's Infant Feeding Choices: Analyzing Self-Efficacy And Narratives From A Black Feminist Perspective, Karen Marie Robinson 2010 Marquette University

African American Women's Infant Feeding Choices: Analyzing Self-Efficacy And Narratives From A Black Feminist Perspective, Karen Marie Robinson

Dissertations (2009 -)

Breast milk is the optimal form of nutrition for infants up to six months of age. Commercial formula is unequal to breast milk nutritionally, economically, and psychologically. African American women (AAW) continue to breastfeed the least compared to other populations. Few researchers conducting research related AAW's infant feeding preferences have employed the Black Feminist philosophy or the theory of self-efficacy. This philosophy and theory may offer insight into factors that influence AAW's infant feeding choices.

The purpose of this mixed-method study was to examine prenatal breastfeeding self-efficacy (confidence) and actively listen to and analyze AAW's reports of ...


Associate Degree Nursing Students' Thoughts, Feelings, And Experiences Of Short Study Abroad In A Low-Income Country, Cynthia Foronda 2010 Marquette University

Associate Degree Nursing Students' Thoughts, Feelings, And Experiences Of Short Study Abroad In A Low-Income Country, Cynthia Foronda

Dissertations (2009 -)

Associate Degree Nursing students are rarely offered opportunities to study abroad. Educational research about nursing students studying abroad is limited but suggests positive outcomes. Prior research has focused on graduate or baccalaureate students in developed and less developed countries, thus, the experience of studying abroad in a low-income country for the associate degree student is unknown. The purpose of this study was to describe the thoughts, feelings, and experiences of associate degree nursing students who participated in a short study abroad course in a low-income country. Ten students participated in phone interviews to share narratives two to six weeks following ...


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