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Acupuncture For The Treatment Of Post Traumatic Stress Disorder, Meghan Goff 2011 Pacific University

Acupuncture For The Treatment Of Post Traumatic Stress Disorder, Meghan Goff

School of Physician Assistant Studies

Background: Of those military service members returning from the current conflict in the Middle East, nearly 20% report symptoms of Post-Traumatic Stress Disorder (PTSD) and only slightly more than half of them seek treatment. Most of these patients are reluctant to participate in traditional interventions such as group or individual psychotherapy, or the supplemental anti-depressives or anxiety pharmaceuticals prescribed to alleviate their symptoms. Through a systematic review of the literature based on GRADE criteria to validate the quality of evidence, this paper seeks to evaluate alternative medicine practices for the treatment of PTSD that are both effective and appealing to ...


Binge Drinking Among Male Mexican Immigrants In Rural North Carolina, Sharon Loury, Darlene Jesse, Q Wu 2011 East Carolina University, College of Nursing

Binge Drinking Among Male Mexican Immigrants In Rural North Carolina, Sharon Loury, Darlene Jesse, Q Wu

D. Elizabeth Jesse

While it is clear that alcohol use among immigrants from Mexico has serious consequences, limited data exist on the correlates of this behavior for Mexican immigrants residing in rural, traditionally non-Hispanic settings. A cross-sectional survey with an outreach approach was used to target 173 male Mexican immigrants in rural eastern North Carolina. Questionnaires including demographics, pre and post immigration alcohol use, acculturation, stress, social support, and depressive symptoms were administered through oral interview by trained bilingual interpreters. Results show a higher prevalence of binge drinking in the study sample compared to rate of alcohol use by Hispanics in the United ...


Validating The Pridit Method For Determining Hospital Quality With Outcomes Data., Robert D. Lieberthal, PhD, Dominique Comer, PharmD, Katherine O’Connell, BS 2011 School of Population Health, Thomas Jefferson University

Validating The Pridit Method For Determining Hospital Quality With Outcomes Data., Robert D. Lieberthal, Phd, Dominique Comer, Pharmd, Katherine O’Connell, Bs

College of Population Health Lectures, Presentations, Workshops

Presented for The 46th Actuarial Research Conference, University of Connecticut, Storrs, CT.

15 PowerPoint slides


Comparative Ecology Of Sarcobatus Baileyi And Sarcobatus Vermiculatus In Eastern California, Rebecca E. Drenovsky, Alynn M. Martin, Molly R. Falasco, James H. Richards 2011 John Carroll University, University Heights, Ohio

Comparative Ecology Of Sarcobatus Baileyi And Sarcobatus Vermiculatus In Eastern California, Rebecca E. Drenovsky, Alynn M. Martin, Molly R. Falasco, James H. Richards

Western North American Naturalist

Greasewood (Sarcobatus) is a succulent-leaved, halophytic shrub of North American origin. The genus comprises 2 species: Sarcobatus baileyi and Sarcobatus vermiculatus.Sarcobatus vermiculatus is common throughout much of western North America, but S. baileyi is much more limited in distribution and was previously thought to be endemic to Nevada. Here we document and describe a S. baileyi population in eastern California, comparing its morphology and ecology to an adjacent S. vermiculatus population. Morphologically, S. baileyi is smaller in stature but produces larger seeds; however, fewer S. baileyi seeds germinated and survived a 20-day laboratory incubation compared to seeds of S ...


Prediction Of Individual Probabilities Of Livebirth And Multiple Birth Events Following In Vitro Fertilization (Ivf): A New Outcomes Counselling Tool For Ivf Providers And Patients Using Hfea Metrics., Christopher A. Jones, Anna L. Christensen, Hamisu Salihu, William Carpenter, Jeffrey Petrozzino, Elizabeth Abrams, E Scott Sills, Louis G. Keith 2011 Center for Study of Multiple Birth, Chicago

Prediction Of Individual Probabilities Of Livebirth And Multiple Birth Events Following In Vitro Fertilization (Ivf): A New Outcomes Counselling Tool For Ivf Providers And Patients Using Hfea Metrics., Christopher A. Jones, Anna L. Christensen, Hamisu Salihu, William Carpenter, Jeffrey Petrozzino, Elizabeth Abrams, E Scott Sills, Louis G. Keith

Obstetrics and Gynaecology Articles

In vitro fertilization (IVF) has become a standard treatment for subfertility after it was demonstrated to be of value to humans in 1978. However, the introduction of IVF into mainstream clinical practice has been accompanied by concerns regarding the number of multiple gestations that it can produce, as multiple births present significant medical consequences to mothers and offspring. When considering IVF as a treatment modality, a balance must be set between the chance of having a live birth and the risk of having a multiple birth. As IVF is often a costly decision for patients-financially, medically, and emotionally-there is benefit ...


Dietary Triglycerides Profoundly Affect Oral Sensitization To Peanut Protein In An Adjuvant-Free Mouse Model Of Peanut Allergy, Erik Eckhardt, Jianing Li 2011 University of Kentucky

Dietary Triglycerides Profoundly Affect Oral Sensitization To Peanut Protein In An Adjuvant-Free Mouse Model Of Peanut Allergy, Erik Eckhardt, Jianing Li

Internal Medicine Presentations

Peanuts and peanut butter contain significant amounts of long-chain triglycerides (LCT), which stimulate lymphatic chylomicron transport. We have recently reported that intestinal absorption of a dietary antigen (ovalbumin; (OVA)) is significantly enhanced when chylomicron formation is induced. This prompted us to investigate the effect of LCT on oral sensitization to concomitantly ingested protein antigens.


The Role Of Sonic Hedgehog In The Hypothalamus, Solsire E. Zevallos 2011 University of Pennsylvania

The Role Of Sonic Hedgehog In The Hypothalamus, Solsire E. Zevallos

Publicly Accessible Penn Dissertations

ABSTRACT

THE REQUIREMENT OF SONIC HEDGEHOG IN THE HYPOTHALAMUS

Solsire E. Zevallos

Douglas J. Epstein

Sonic hedgehog (Shh) is a morphogen secreted during early development that is required for the formation of the ventral neural tube, including the ventral forebrain. The prechordal source of Shh underlying the forebrain is required early to bifurcate the cerebral hemispheres and eye vesicles as well as to specify a rostroventral forebrain region, the hypothalamus. We hypothesized that Shh expressed later in the hypothalamus may be required for other known functions of Shh, such as patterning within a region, cell proliferation, cell specification, and axon ...


Emergency Department Psychiatric Assessment For Adults Discharged With A Principal Diagnosis Of Schizophrenia In Maryland Community Hospitals With And Without Inpatient Psychiatric Units, Patricia A. White 2011 University of Pennsylvania

Emergency Department Psychiatric Assessment For Adults Discharged With A Principal Diagnosis Of Schizophrenia In Maryland Community Hospitals With And Without Inpatient Psychiatric Units, Patricia A. White

Publicly Accessible Penn Dissertations

Same as previous submission


Liquid Chromatography – Mass Spectrometry For Protein Biomarker Discovery In Pancreatic Adenocarcinoma, Angela Y. Wehr 2011 University of Pennsylvania

Liquid Chromatography – Mass Spectrometry For Protein Biomarker Discovery In Pancreatic Adenocarcinoma, Angela Y. Wehr

Publicly Accessible Penn Dissertations

Pancreatic cancer has one of the lowest survival rates of all cancers, partly due to the difficulty of detection in its early stages. Recent developments in liquid chromatography – mass spectrometry (LC-MS) technology have made it possible to profile proteins associated with disease in a comprehensive manner. Within this thesis current LC-MS methodology was applied to the problem of pancreatic cancer.

A comprehensive list of proteins secreted by the tumor microenvironment was compiled in the first aim. Culture of pancreatic cell lines was used to simulate the tumor microenvironment in vitro and produce a proteome rich in biomarkers. The proteins identified ...


Role Of Hippocampal Neurogenesis In The Etiology And Treatment Of Mood & Anxiety Disorders, Jennifer L. Onksen 2011 University of Pennsylvania

Role Of Hippocampal Neurogenesis In The Etiology And Treatment Of Mood & Anxiety Disorders, Jennifer L. Onksen

Publicly Accessible Penn Dissertations

Mood disorders are associated with deficits in hippocampal size and function. Neurogenesis in the dentate gyrus of the hippocampus has been implicated in the behavioral efficacy of some antidepressants. However, the precise function of newborn hippocampal neurons in the etiology and treatment of mood disorders remains unclear. Anxiety, which is highly comorbid with mood disorders, also appears to be influenced by neurogenesis. The intricacies of this influence are poorly understood. Here, the role of neurogenesis in the pathophysiology and treatment of mood and anxiety disorders is investigated in a transgenic mouse exhibiting partial suppression of hippocampal neurogenesis. This reduction is ...


The Generation Of Fully Functional Β-Cells By Proliferation: Lessons From Pregnancy And Hnf4Α, Sebastian Rieck 2011 University of Pennsylvania

The Generation Of Fully Functional Β-Cells By Proliferation: Lessons From Pregnancy And Hnf4Α, Sebastian Rieck

Publicly Accessible Penn Dissertations

Diabetes mellitus is an increasingly prevalent metabolic disorder that is estimated to affect over 300 million people by 2025. Common to either type 1 or type 2 diabetes is a progressive inadequacy of functional β-cell mass. Recent studies have shown that during times of prolonged metabolic demand for insulin, the endocrine pancreas can respond by increasing β-cell mass, both by an increase in cell size and by changes in the balance of β-cell proliferation and apoptosis. Advances that further our knowledge of the molecular factors that control both β-cell proliferation and survival will be crucial for understanding the homeostasis of ...


Role And Regulation Of Myosin Iia In Natural Killer Cell Cytotoxicity, Keri Sanborn 2011 University of Pennsylvania

Role And Regulation Of Myosin Iia In Natural Killer Cell Cytotoxicity, Keri Sanborn

Publicly Accessible Penn Dissertations

Natural killer (NK) cells are lymphocytes of the innate immune system that provide defense by directing their cytotoxic activity against virally infected and tumorigenic cells. Target cell lysis requires directed secretion of lytic granule contents, including pore-forming perforin and apoptosis-inducing granzymes, at the contact site. During the formation of a mature immunological synapse (IS) with a target cell, an NK cell polymerizes filamentous actin (F-actin) at the contact site, which may serve as a barrier to secretion of lytic granules for cytotoxicity. An actin-based motor protein, nonmuscle myosin IIA, has been demonstrated to be required for NK cell cytotoxic activity ...


End Matter, Vol. 71 No. 2, 2011 Brigham Young University

End Matter, Vol. 71 No. 2

Western North American Naturalist

No abstract provided.


Transcriptome Sequencing Of The Blind Subterranean Mole Rat, Spalax Galili: Utility And Potential For The Discovery Of Novel Evolutionary Patterns, Assaf Malik, Abraham Korol, Sariel Hubner, Aaron Avivi, Alvaro Hernandez, Jyothi Thimmapuram, Shahjahan Ali, Mark Bond, Fabian Glaser, Arnon Paz 2011 University of Haifa

Transcriptome Sequencing Of The Blind Subterranean Mole Rat, Spalax Galili: Utility And Potential For The Discovery Of Novel Evolutionary Patterns, Assaf Malik, Abraham Korol, Sariel Hubner, Aaron Avivi, Alvaro Hernandez, Jyothi Thimmapuram, Shahjahan Ali, Mark Bond, Fabian Glaser, Arnon Paz

Cyber Center Publications

The blind subterranean mole rat (Spalax ehrenbergi superspecies) is a model animal for survival under extreme environments due to its ability to live in underground habitats under severe hypoxic stress and darkness. Here we report the transcriptome sequencing of Spalax galili, a chromosomal type of S. ehrenbergi. cDNA pools from muscle and brain tissues isolated from animals exposed to hypoxic and normoxic conditions were sequenced using Sanger, GS FLX, and GS FLX Titanium technologies. Assembly of the sequences yielded over 51,000 isotigs with homology to ~12,000 mouse, rat or human genes. Based on these results, it was possible ...


Seed Bank Dynamics And Habitat Indicators Of Arctomecon Californica, A Rare Plant In A Fragmented Desert Environment, Laura Megill, Lawrence R. Walker, Cheryl Vanier, Debra Johnson 2011 University of Nevada, Las Vegas

Seed Bank Dynamics And Habitat Indicators Of Arctomecon Californica, A Rare Plant In A Fragmented Desert Environment, Laura Megill, Lawrence R. Walker, Cheryl Vanier, Debra Johnson

Western North American Naturalist

Protection of endangered desert plant species is frequently complicated by a lack of information about seeds, the most stress-resistant and populous life stage. We studied the relative locations of seeds and plants of a rare endangered herbaceous perennial, the Las Vegas bearpoppy (Arctomecon californica) in seven 1-ha sites randomly located within a 100-ha study area that was slated for development in Las Vegas, Nevada. We also measured the physical and biological attributes of the environment supporting the seeds and plants, including soil hardness, rock cover, cryptogamic crust cover, and associated vegetation.

Arctomecon californica seed density was 0.651 seeds · m ...


Pipeline Predictor Rx, Timothy Cummins 2011 University of Massachusetts Medical School

Pipeline Predictor Rx, Timothy Cummins

Commonwealth Medicine Publications

Pipeline PredictorRx™ evaluates new drugs, expected to have a significant clinical or financial impact when approved by the FDA, and compares them to current therapies.

This UMass Medical School model, entirely independent of drug company interests, goes beyond detailing pharmacy outcomes for pipeline drugs — we also examine the potential for avoiding hospitalization and other medical costs.


Effects Of Elevation On Litter-Size Variation Among Lizard Populations In The Sceloporus Grammicus Complex (Phrynosomatidae) In Mexico, Aurelio Ramírez-Bautista, Adrian Leyte-Manrique, Jonathon C. Marshall, Geoffrey R. Smith 2011 Centro de Investigaciones Biólogicas, Universidad Autónoma del Estado de Hidalgo, Hidalgo, México

Effects Of Elevation On Litter-Size Variation Among Lizard Populations In The Sceloporus Grammicus Complex (Phrynosomatidae) In Mexico, Aurelio Ramírez-Bautista, Adrian Leyte-Manrique, Jonathon C. Marshall, Geoffrey R. Smith

Western North American Naturalist

We examined the effect of elevation on litter-size variation in viviparous lizards of theSceloporus grammicus complex in 10 states of Mexico. Female snout–vent length (SVL) decreased with increasing elevation, and absolute litter size based on embryos also tended to de crease with increasing elevation. However, after controlling for variation in female body size, we found that litter sizes tended to be relatively larger at higher elevation. Elevation therefore appears to influence litter size in these lizards; however, relatively little of the variation is explained by elevation; thus, other factors are likely making substantial contributions to the observed litter-size ...


Effects Of Wildfire And Postfire Floods On Stonefly Detritivores Of The Pajarito Plateau, New Mexico, Nicole K. M. Vieira, Tiffany R. Barnes, Katharine A. Mitchell 2011 Colorado State University, Fort Collins and Colorado Parks and Wildlife, Wildlife Research Center, Fort Collins, Colorado

Effects Of Wildfire And Postfire Floods On Stonefly Detritivores Of The Pajarito Plateau, New Mexico, Nicole K. M. Vieira, Tiffany R. Barnes, Katharine A. Mitchell

Western North American Naturalist

Wildfires alter the quantity and quality of allochthonous detritus in streams by burning riparian vegetation and through flushing during postfire floods. As such, fire disturbance may negatively affect detritivorous insects that consume coarse organic matter. We assessed how 2 crown fires impacted stonefly detritivores in streams of the Pajarito Plateau, New Mexico. We documented stonefly populations before and after the fires and postfire floods, and compared recovery trajectories among unburned, lightly burned, and severely burned reaches. We also conducted experiments to assess burned detritus as a food resource for Pteronarcella badia Hagen. Specifically, we characterized microbial conditioning, nutrient content, and ...


In Vivo Cellular Mri In Experimental Traumatic Spinal Cord Injury, Laura E. Gonzalez-Lara 2011 The University of Western Ontario

In Vivo Cellular Mri In Experimental Traumatic Spinal Cord Injury, Laura E. Gonzalez-Lara

Electronic Thesis and Dissertation Repository

Spinal cord injury (SCI) remains one of the most devastating conditions in medicine; it is a complex medical condition with no cure currently available. Inflammation plays an important role in SCI as it can have both beneficial and detrimental effects. Cell therapy has emerged as a promising treatment for SCI due to the potential for stem cells, including multipotent mesenchymal stromal cells (MSC), for tissue regeneration and immunomodulation of the inflammatory cascade after the initial trauma. However, there are still important, unresolved questions regarding cell therapy that magnetic resonance imaging (MRI) can help to address by producing high-resolution images with ...


A Reconnaissance Of Small Mammal Communities In Garland And Government Prairies, Arizona, Joseph L. Ganey, Carol L. Chambers 2011 USDA Forest Service, Rocky Mountain Research Station, Flagstaff, Arizona

A Reconnaissance Of Small Mammal Communities In Garland And Government Prairies, Arizona, Joseph L. Ganey, Carol L. Chambers

Western North American Naturalist

Small mammals play key ecological roles in grassland ecosystems, yet little is known regarding small mammal communities in large (>50 km2), high-elevation prairies embedded in ponderosa pine (Pinus ponderosa) forests in north central Arizona. To provide information on community composition and habitat relationships, we live-trapped small mammals on 6 transects in 2 prairies in 2008. We captured 78 individuals in 5501 trap occasions. Capture rates were low and varied widely among transects. Community composition was simple, with only 3 species of small mammals captured. In order of relative abundance, these species were deer mouse (Peromyscus maniculatus, n = 44 individuals ...


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