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Phase Iii, Randomized, Double-Blind, Placebo-Controlled Evaluation Of Pregabalin For Alleviating Hot Flashes, N07c1, Charles L. Loprinzi, Rui Qin, Ernie P. Baclueva, Donald J. Jurgens 2010 Mayo Clinic, Rochester

Phase Iii, Randomized, Double-Blind, Placebo-Controlled Evaluation Of Pregabalin For Alleviating Hot Flashes, N07c1, Charles L. Loprinzi, Rui Qin, Ernie P. Baclueva, Donald J. Jurgens

Articles

PURPOSE:

Hot flashes are a common problem for which effective and safe treatments are needed. The current trial was conducted on the basis of preliminary promising data that pregabalin decreased hot flashes.

PATIENTS AND METHODS:

A double-blind, placebo-controlled, randomized trial design was used to compare pregabalin at target doses of 75 mg twice daily and 150 mg twice daily with a placebo. Hot flash frequencies and scores (frequency times mean severity) were recorded daily during a baseline week and for six treatment weeks. The primary end point for this study was the change-from-baseline hot flash score during treatment week 6 ...


Diffusion Weighted Mr Imaging (Dwi) And Adc Values In Endometrial Carcinoma, Imrana Masroor, Muhammad Zeeshan, Shaista Afzal, Nadeem Ahmad, Gulnaz Shafqat 2010 Aga Khan University

Diffusion Weighted Mr Imaging (Dwi) And Adc Values In Endometrial Carcinoma, Imrana Masroor, Muhammad Zeeshan, Shaista Afzal, Nadeem Ahmad, Gulnaz Shafqat

Department of Radiology

Objective: To determine the sensitivity of MR imaging utilizing diffusion weighted imaging (DWI) in detection of endometrial cancer and to compare the Apparent Diffusion Coefficient (ADC) values of malignant and normal endometrium.

Study Design: Cross-sectional analytical study.

Place and Duration of Study: Radiology Department, Aga Khan University Hospital Karachi, from January 2007 to December 2009. Methodology: Patients were defined as undergoing MRI for suspected endometrial malignancy, and the controls were female subjects who underwent MRI examination for indications other than endometrial malignancy. Studied variables included the signal characteristics of the endometrium and ADC values. The sensitivity of DWI for the ...


Chhs November E-Newsletter, College of Health and Human Services, Western Kentucky University, VaShon S. Wells, editor 2010 Western Kentucky University

Chhs November E-Newsletter, College Of Health And Human Services, Western Kentucky University, Vashon S. Wells, Editor

College of Health & Human Services Publications

No abstract provided.


Chart Rounds In The Digital Age: A Survey Of North American Institutions, M. A. Whiton, A. P. Dicker, E. J. Wuthrick, L. Doyle, A. S. Harrison, Y. R. Lawrence 2010 Skagit Valley Hospital Regional Cancer Care Center, Mt. Vernon, WA

Chart Rounds In The Digital Age: A Survey Of North American Institutions, M. A. Whiton, A. P. Dicker, E. J. Wuthrick, L. Doyle, A. S. Harrison, Y. R. Lawrence

Department of Radiation Oncology Faculty Papers

Purpose:

Recent reports of medical errors in radiaKon treatment delivery have emphasized the importance of quality assurance (QA) pracKces. Strict guidelines exist for medical physics QA, but not for QA procedures as applied to clinicians. We sought to document how clinical quality assurance (QA) meeKngs or “chart rounds” are performed across academic North American RadiaKon Oncology departments.


Quantitative Risk From Fluoroquinolone-Resistant Salmonella And Campylobacter Due To Treatment Of Dairy Heifers With Enrofloxacin For Bovine Respiratory Disease, H. Scott Hurd, Michael B. Vaughn, Derald J. Holtkamp, James S. Dickson, Lorin Warnick 2010 Iowa State University

Quantitative Risk From Fluoroquinolone-Resistant Salmonella And Campylobacter Due To Treatment Of Dairy Heifers With Enrofloxacin For Bovine Respiratory Disease, H. Scott Hurd, Michael B. Vaughn, Derald J. Holtkamp, James S. Dickson, Lorin Warnick

Animal Science Publications

The objective of this study was to evaluate the human health impact of using fluoroquinolones to treat bovine respiratory disease (BRD) in dairy heifers less than 20 months of age. Specifically, this study quantified the probability of persistent symptoms in humans treated with a fluoroquinolone, for a fluoroquinolone-resistant Campylobacter, Salmonella, or multidrug-resistant (MDR) Salmonella infection acquired following the consumption of ground beef. To comply with a Food and Drug Administration requirement for approval of enrofloxacin use in dairy heifers, a binomial event tree was constructed following Food and Drug Administration guidance 152. Release was estimated from the slaughter of dairy ...


An Exploration Of "The 'Wild West' Of Reproductive Technology": Ethical And Feminist Perspectives On Sex-Selection Practices In The United States, Meredith Leigh Birdsall 2010 College of William & Mary Law School

An Exploration Of "The 'Wild West' Of Reproductive Technology": Ethical And Feminist Perspectives On Sex-Selection Practices In The United States, Meredith Leigh Birdsall

William & Mary Journal of Women and the Law

No abstract provided.


Critical Illness Myopathy, Salima Moez Meherali, Yasmin Parpio, Tazeen Ali 2010 Aga Khan University

Critical Illness Myopathy, Salima Moez Meherali, Yasmin Parpio, Tazeen Ali

School of Nursing & Midwifery

Critical illness myopathy (CIM) is a syndrome of widespread muscle weakness and neurological dysfunction which can develop in critically ill patients receiving intensive care. CIM are often distinguished largely on the basis of specialized electrophysiologic testing or muscle and nerve biopsy and its causes are unknown, though they are thought to be a possible neurological manifestation of systemic inflammatory response syndrome usually developing in patients after a brief period of stay in the Intensive Care Unit (ICU). This case report aims to analyze the Clinical feature, diagnosis and treatment of CIM of 60 years old male case with Chronic Obstructive ...


Relationship Of Personal, Familial, And Abuse-Specific Factors With Outcome Following Childhood Sexual Abuse, C. Thresa Yancey, David J. Hansen 2010 Georgia Southern University

Relationship Of Personal, Familial, And Abuse-Specific Factors With Outcome Following Childhood Sexual Abuse, C. Thresa Yancey, David J. Hansen

Faculty Publications, Department of Psychology

An examination of the literature on factors related to outcome following child sexual abuse (CSA) revealed many factors that may contribute to symptoms displayed by victims. Factors are divided into three categories: Personal Factors, Familial Factors, and Abuse- Specific Factors. Personal factors are those inherent to the victim, including age, gender, developmental disability, attributions regarding the abuse, and treatment following abuse. Familial factors are defined as those factors associated with other family members. These include parental history of abuse, parental reaction to the disclosure, parental support of the victim, parental mental health, family stress, and treatment following abuse for the ...


Image And Video Disclosure Of Substance Use On Social Media Websites, Elizabeth M. Morgan, Chareen Snelson, Patt Elison-Bowers 2010 Boise State University

Image And Video Disclosure Of Substance Use On Social Media Websites, Elizabeth M. Morgan, Chareen Snelson, Patt Elison-Bowers

Psychological Sciences Faculty Publications and Presentations

The present study examines young adults’ use of social media websites, such as MySpace, Facebook, and YouTube, to post public images and videos of themselves depicting alcohol consumption, inebriated behavior, or recreational marijuana use. A content analysis revealed that the majority of image and video representations of alcohol consumption depicted females in social gatherings while images and videos depicting marijuana use depicted solitary males. Videos typically were viewed frequently and gained positive ratings. Among a sample of college students, one-third of participants reported having posted a picture depicting substance use on a social networking site, with 97 percent aware that ...


Creating Opportunities For Success: Working With Trauma Survivors In The Shelter Setting, Joanne Nicholson, Linda F. Weinreb, Tina Runyan, Kathleen Biebel 2010 University of Massachusetts Medical School

Creating Opportunities For Success: Working With Trauma Survivors In The Shelter Setting, Joanne Nicholson, Linda F. Weinreb, Tina Runyan, Kathleen Biebel

Systems and Psychosocial Advances Research Center Publications and Presentations

Summary: Training workshop with the following objectives: Increase knowledge, awareness, & understanding of trauma & its impact; Provide information about skills & strategies; Suggest self care strategies.

Citation: Nicholson, J., Weinreb, L., Runyan, T., & Biebel, K. (2010, November). Creating opportunities for success: Working with trauma survivors in the shelter setting. Presented at a training workshop for the Central Massachusetts Housing Alliance, Worcester, MA.


The Challenges Of Understanding Animal Minds, Jeffrey R. Stevens 2010 University of Nebraska-Lincoln

The Challenges Of Understanding Animal Minds, Jeffrey R. Stevens

Faculty Publications, Department of Psychology

Comparative psychology is by nature an interdisciplinary science that lies at the crossroads of psychology and biology but also draws from other fields in the natural, social, and cognitive sciences. The study of the psychology of animals has been labeled animal cognition, comparative cognition, animal learning, animal psychology, and animal intelligence. Here, comparative psychology is used interchangeably with these terms, encompassing all fields that explore the psychological mechanisms underlying animal behavior, including human behavior.

The primary goal of comparative psychology is to understand the cognitive, emotional, and motivational processes of the animal mind. How do other animals perceive, learn about ...


Investment In Paediatric Tuberculosis Prevention In Pakistan: Loss Or Gain, Emad uddin Siddiqui, Kiran Ejaz, Saira Lone, Syed Jamal Raza 2010 Aga Khan University

Investment In Paediatric Tuberculosis Prevention In Pakistan: Loss Or Gain, Emad Uddin Siddiqui, Kiran Ejaz, Saira Lone, Syed Jamal Raza

Department of Paediatrics and Child Health

OBJECTIVE: To assess the effectiveness of paediatric tuberculosis prevention, by reevaluation factors in children exposed to tuberculosis from less privileged strata of Pakistan.

METHODS: This cross sectional descriptive study was conducted at National Institute of Child Health, from January 2004 to December 2005. Paediatric patients under 15 years of either gender, diagnosed with active tuberculosis were enrolled. Interviews were conducted with parents regarding common preventive measures and factors advocating tuberculosis spread. Later factors leading to non-compliance to safety recommendations were also evaluated.

RESULTS: Fifty five (70%) children younger than 5 years, had index cases in direct contact within their own ...


Gender-Specific Profiles Of Tobacco Use Among Non-Institutionalized People With Serious Mental Illness, Joy Johnson, Pamela Ratner, Leslie Malchy, Chizimuzo Okoli, Ric Procyshyn, Joan Bottorff, Marlee Groening, Annette Schultz, Marg Osborne 2010 University of Kentucky

Gender-Specific Profiles Of Tobacco Use Among Non-Institutionalized People With Serious Mental Illness, Joy Johnson, Pamela Ratner, Leslie Malchy, Chizimuzo Okoli, Ric Procyshyn, Joan Bottorff, Marlee Groening, Annette Schultz, Marg Osborne

Chizimuzo T.C. Okoli

Background: In many countries, smoking remains the leading preventable cause of death. In North America, reductions in population smoking levels are stabilising and, in recent years, those involved in tobacco control programming have turned their attention to particular segments of society that are at greatest risk for tobacco use. One such group is people with mental illness. A picture of tobacco use patterns among those with mental illness is beginning to emerge; however, there are several unanswered questions. In particular, most studies have been limited to particular in-patient groups. In addition, while it is recognised that men and women differ ...


Effects Of High Intraoperative Inspired Oxygen On Postoperative Nausea And Vomiting In Gynecologic Laparoscopic Surgery, Tatjana Šimurina, MD, MSc, Boris Mraović, MD, Simon Mikulandra, MD, MSc, Zdenko Sonicki, MD, PhD, Nina Sulen, MD, Branko Dukić, MD, Tong J. Gan, M.D 2010 General Hospital, Zadar, Croatia

Effects Of High Intraoperative Inspired Oxygen On Postoperative Nausea And Vomiting In Gynecologic Laparoscopic Surgery, Tatjana Šimurina, Md, Msc, Boris Mraović, Md, Simon Mikulandra, Md, Msc, Zdenko Sonicki, Md, Phd, Nina Sulen, Md, Branko Dukić, Md, Tong J. Gan, M.D

Department of Anesthesiology Faculty Papers

Study objective: To assess the efficacy of intraoperative different inspired oxygen fractions (FIO2) of 0.8 and 0.5 when compared with standard FIO2 0.3 in prevention of postoperative nausea and vomiting (PONV).

Design: A prospective, controlled, randomized, double-blind study.

Setting: General hospital, postanesthesia care unit (PACU) and gynecologic floor room. Patients: 120 ASA physical status I and II women, aged 21 to 76 y, undergoing elective gynecologic laparoscopic surgery.

Interventions: Patients were randomized to receive gas mixture of 30% oxygen in air (FI O2=0.3, group G30), 50% oxygen in air (FIO2=0.5, group G50) or ...


Knowledge, Attitudes, And Practice Behaviors Of Oncology Advanced Practice Nurses Regarding Advanced Care Planning For Patients With Cancer., Guiyun Zhou, DNP, CRNP, AOCNS, Jill C Stoltzfus, PhD, Arlene D Houldin, PhD, PMHCNS-BC, Susan M Parks, MD, Beth Ann Swan, PhD, CRNP, FAAN 2010 Vita Medical Associates

Knowledge, Attitudes, And Practice Behaviors Of Oncology Advanced Practice Nurses Regarding Advanced Care Planning For Patients With Cancer., Guiyun Zhou, Dnp, Crnp, Aocns, Jill C Stoltzfus, Phd, Arlene D Houldin, Phd, Pmhcns-Bc, Susan M Parks, Md, Beth Ann Swan, Phd, Crnp, Faan

College of Nursing Faculty Papers & Presentations

Purpose/Objectives: To establish initial reliability and validity of a Web-based survey focused on oncology advanced practice nurses' (APNs') knowledge, attitudes, and practice behaviors regarding advanced care planning, and to obtain preliminary understanding of APNs' knowledge, attitudes, and practice behaviors and perceived barriers to advanced care planning.

Design: Descriptive, cross-sectional, pilot survey study.

Setting: The eastern United States.Sample: 300 oncology APNs.Methods: Guided by the Theory of Planned Behavior, a knowledge, attitudes, and practice behaviors survey was developed and reviewed for content validity. The survey was distributed to 300 APNs via e-mail and sent again to the 89 APNs ...


Successful Management Of Invasive Aspergillosis With Voriconazole And Amphoteracin B Therapy In A Patient With Acute Mycloid Leukemia (Aml-M2), Nauman Fazal Manzoor, Sidra Azim, Zehra Fadoo 2010 Aga Khan University

Successful Management Of Invasive Aspergillosis With Voriconazole And Amphoteracin B Therapy In A Patient With Acute Mycloid Leukemia (Aml-M2), Nauman Fazal Manzoor, Sidra Azim, Zehra Fadoo

Department of Paediatrics and Child Health

An eleven-year-old boy presented with one month's history of fever and weight loss. He was diagnosed with Acute Mycloid Leukemia (AML-M2). During treatment he developed recurrent infections with neutropenia requiring prolonged antibiotics and subsequently developed invasive aspergillosis. He was treated with amphotericin B and Voriconazole. This case shows the efficacy and safety of combined antifungal therapy, including voriconazole, for invasive aspergillosis complicating AML.


Reducing Mislabeled Specimen Through Lean Processes., Kay Ruachfuss MSN, RN 2010 Lehigh Valley Health Network

Reducing Mislabeled Specimen Through Lean Processes., Kay Ruachfuss Msn, Rn

Patient Care Services / Nursing

No abstract provided.


From B17 Bomber To Bedside: Using A Bundle Methodology To Enhance Quality, Kim Jordan MHA, BSN, RN, NE-BC, Carolyn L. Davidson PhD, RN, CCRN, FNP-BC, Debra Peter MSN, RN-BC, Kim Holleran BSN, RN, CMSRN 2010 Lehigh Valley Health Network

From B17 Bomber To Bedside: Using A Bundle Methodology To Enhance Quality, Kim Jordan Mha, Bsn, Rn, Ne-Bc, Carolyn L. Davidson Phd, Rn, Ccrn, Fnp-Bc, Debra Peter Msn, Rn-Bc, Kim Holleran Bsn, Rn, Cmsrn

Patient Care Services / Nursing

No abstract provided.


A Severe Case Of Necrotizing Fasciitis Of The Abdomen: A Survivor Story, Karin McConville MD, Dale A. Dangleben MD, Rovinder S. Sandhu MD 2010 Lehigh Valley Health Network

A Severe Case Of Necrotizing Fasciitis Of The Abdomen: A Survivor Story, Karin Mcconville Md, Dale A. Dangleben Md, Rovinder S. Sandhu Md

Department of Surgery

No abstract provided.


Rhnull: A Rare Blood Group Phenotype, Adnan Qureshi, Muhammad Salman, Bushra Moiz 2010 Aga Khan University

Rhnull: A Rare Blood Group Phenotype, Adnan Qureshi, Muhammad Salman, Bushra Moiz

Section of Internal Medicine

Rhnull phenotype is a rare blood group characterized by the lack of expression of all Rh antigens (D, C, c, E and e) on the red cells. The phenotype is further classified into the regulator and amorph type based on underlying genetic defect. The clinical significance of its recognition is that such patients suffer from Rhnull syndrome associated with osmotically fragile red cells called stomatocytes with subsequent chronic haemolytic anaemia of varying degree. Another importance is that such subjects readily form alloantibodies on exposure to Rh antigens. We report herein rare Rhaull phenotype in a young pregnant female which was ...


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