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Orientation to Center for Teaching and Learning and Scott Memorial Library services for students.

Socioeconomic Status, Air Quality And Geographic Variation In Emergency Room Visits For Acute Bronchitis On The California Central Coast, Sean Lang-Brown, Heather W. Starnes, Gary B. Hughes

Symposium

IMPORTANCE: Analysis of geospatial variation in acute bronchitis due to socioeconomic and environmental factors can allow the efficient delivery of resources to populations most at risk.

OBJECTIVE: We sought to determine if small scale variation in socioeconomic factors and emergency room (ER) visits for acute bronchitis are associated in small cities or rural communities. We also modeled the effects of air quality on daily rates of ER visits for acute bronchitis in the context of socioeconomic factors to investigate modifying relationships.

DESIGN, SETTING, AND PARTICIPANTS: We examined ER visits for acute bronchitis in San Luis Obispo and Santa Barbara counties ...

Supporting And Retaining Village Health Teams: An Assessment Of A Community Health Worker Program In Two Ugandan Districts., Daniel C Mays, Edward J O'Neil, Edison A Mworozi, Benjamin J Lough, Zachary J Tabb, Ashlyn E Whitlock, Edward M Mutimba, Zohray M Talib

Health Policy and Management Faculty Publications

Background

Uganda’s national community health worker program involves volunteer Village Health Teams (VHTs) delivering basic health services and education. Evidence demonstrates their positive impact on health outcomes, particularly for Ugandans who would otherwise lack access to health services. Despite their impact, VHTs are not optimally supported and attrition is a growing problem. In this study, we examined the support needs and existing challenges of VHTs in two Ugandan districts and evaluated specific factors associated with long-term retention. We report on findings from a standardized survey of VHTs and exploratory interviews with key stakeholders and draw conclusions that inform efforts ...

Exercise Professionals: Barriers And Facilitators To Working With Stroke Survivors, Marie Condon

Mary Condon

Introduction: Stroke survivors (SSs) are largely inactive despite the benefits of exercise. Community-based exercise professionals (EPs) skilled in exercise prescription and personal motivation may have a role to play in promoting exercise for SSs. However, little is known about EPs’ opinions towards working with SSs. Aims: To investigate EPs’ opinions towards working with SSs. Objectives: To identify EPs’ barriers and facilitators towards working with SSs and to investigate their relationship with EPs education on stroke. To investigate EPs skills, interest and experience working with SSs.
Methods: A descriptive study was conducted using an online survey designed by the researcher. Purposive ...

Adenovirus Prime, Env Protein Boost Vaccine Protects Against Neutralization-Resistant Sivsme660 Variants In Rhesus Monkeys, Brandon F. Keele, Wenjun Li, Erica N. Borducchi, Joseph P. Nkolola, Peter Abbink, Bing Chen, Michael S. Seaman, Dan H. Barouch

Wenjun Li

Previous studies have shown that DNA prime, Ad5 boost vaccines protect against neutralization-sensitive but not neutralization-resistant virus variants within the SIVsmE660 swarm. Here we show that Ad prime, Env protein boost vaccines protect against neutralization-resistant SIVsmE660 variants. We perform two studies in rhesus monkeys with Ad35/Ad26 vectors expressing SIVmac239 Gag/Pol/Env with or without an AS01B-adjuvanted SIVmac32H gp140 protein boost. In a repetitive, low-dose challenge study, we observe robust protection against acquisition of infection by both Ad Alone and Ad/Env vaccines. In a single, high-dose challenge study, only the Ad/Env vaccine affords significant protection against acquisition ...

Adaptation Of Community Health Worker-Delivered Behavioral Activation For Torture Survivors In Kurdistan, Iraq, J. F. Magidson, C. W. Lejuez, T. Kamal, E. J. Blevins, L. K. Murray, J. K. Bass, P. Bolton, Sherry L. Pagoto

Sherry L. Pagoto

BACKGROUND: Growing evidence supports the use of Western therapies for the treatment of depression, trauma, and stress delivered by community health workers (CHWs) in conflict-affected, resource-limited countries. A recent randomized controlled trial (Bolton et al. 2014a) supported the efficacy of two CHW-delivered interventions, cognitive processing therapy (CPT) and brief behavioral activation treatment for depression (BATD), for reducing depressive symptoms and functional impairment among torture survivors in the Kurdish region of Iraq. METHODS: This study describes the adaptation of the CHW-delivered BATD approach delivered in this trial (Bolton et al.2014a), informed by the Assessment-Decision-Administration-Production-Topical experts-Integration-Training-Testing (ADAPT-ITT) framework for intervention adaptation ...

Home Care Quality Effects Of Remote Monitoring, Cynthia Williams

Cynthia A. Williams

Despite concerted efforts to decrease costs and increase public health, the embattled U.S. health care system continues to struggle to alleviate these widespread issues. Because the problem of hospital utilizations among patients with heart failure is posited to increase as the population ages, innovative methodologies need to be explored to mitigate adverse events. Remote monitoring harnesses the strength of advanced information and communication technology to affect positive changes in health care quality and cost. By reaching across geographical boundaries, remote monitoring may support increased access to less costly services and improve the quality of home health care. The purpose ...

Choices: A Family-Based Childhood Obesity Intervention For Low Income Minority Children, Cynthia Williams Brown, Claudia Warren, Marian Booker

Cynthia A. Williams

Low-income children are at increased risk for obesity (Kumanyika & Grier, 2006) with the rate of obesity among minority children being more than double that of white children (Ogden, 2010). Many interventions fail to understand and take into consideration the unique environmental factors that influence behaviors in low-income minority children (Kumanyika & Grier, 2006). The proposed program, Childhood Health and Obesity Initiative: Communities Empowered for Success (CHOICES) is an obesity prevention intervention implemented in a summer camp setting targeting 10-12 year-old children from low income families. The long-term goal of the project is to reduce the prevalence of childhood obesity for minority ...

Validity And Reliability Of A Submaximal Intermittent Running Test In Elite Australian Football Players, Kristopher Veugelers, Geraldine Ann Naughton, Craig Scott Duncan, Darren Burgess, Stuart Graham

Craig M. Scott

Abstract: Veugelers, KR, Naughton, GA, Duncan, CS, Burgess, DJ, and Graham, SR. Validity and reliability of a submaximal intermittent running test in elite Australian football players. J Strength Cond Res 30(12): 3347–3353, 2016—The aim of this article was to determine the validity and reliability of a submaximal intermittent running (SIR) test in elite Australian rules football (ARF) players. Heart rate (HR) responses of 38 elite ARF players to both the SIR and the yo-yo intermittent recovery 2 (YYIR2) tests were compared over 2 trials. Linear regression analysis was used to examine the relationship between SIR test HR ...

Navigating To Health: Evaluation Of A Community Health Center Patient Navigation Program, Monica L. Wang, Leah Gallivan, Stephenie C. Lemon, Amy Borg, Jose Ramirez, Brenda Figueroa, Antonia Mcguire, Milagros C. Rosal

Milagros C. Rosal

Patient Navigators are trained, lay health care workers who guide patients in overcoming barriers to health care access and utilization. Little evidence exists regarding reach and impact of Patient Navigators for chronic disease management. This study evaluated a Patient Navigator program aimed at optimizing health care utilization among ethnically diverse patients with diabetes and/or hypertension at a community health center (CHC). Trained Patient Navigators contacted eligible patients who had not seen a primary care provider (PCP) for > /= 6 months. Outcomes included number of patients reached by Patient Navigators and seen by PCPs after Patient Navigator contact. Distributions and frequencies ...

Rethinking Animal Agriculture: A Principlist Approach, Miranda S. Eisen 3412335

Sound Decisions: An Undergraduate Bioethics Journal

Engrained in the mindless routines of our daily lives, we believe our consumer choices do not matter. But participating in the animal industrial complex through the purchase and consumption of meat, dairy and eggs generates significant bioethical issues that warrant exploration and discussion. This paper examines the moral rights of animals, poor ethical justification of animal consumption, and extreme ramifications of the animal agricultural system within the framework of principlism. By analyzing the moral position of animal consumption in the bioethical context of utility, autonomy, nonmaleficence, beneficence and justice, the corrupt nature of animal agribusiness is revealed and plant-based living ...

Translational Research: Ethical Considerations, Yiqing Dong

Sound Decisions: An Undergraduate Bioethics Journal

Translational research (TR) is a new categorization for the efforts of biomedical research and emphasizes efficiency in achieving population health improvements through the application of basic science knowledge in clinical practice. It will be argued that the current emphasis on speed and collaboration with industry established by national policies provides challenges to maintaining the integrity of scientific research. There is no agreed upon definition of TR and the current standard of judging the success of TR focuses on product production. I propose that the principles of beneficence and responsive justice should be used to inform the values of TR and ...

08-08-2017 Notice Of The Hsc Committee Meeting, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

The ‘Undue Burden’ Of Restrictions On Abortion: A Feminist Bioethics Analysis, Samantha Scott

Sound Decisions: An Undergraduate Bioethics Journal

This paper examines the ethical issues of abortion from a framework of undue burden. The definition of undue burden of abortion is taken from Planned Parenthood of Southeastern Pennsylvania v. Casey (1992) supreme court decision and states: “its purpose or effect is to place a substantial obstacle in the path of the woman seeking an abortion before the fetus attains viability.” Specifically, this paper argues that abortion restrictions waiting periods and parental involvement do in fact place an undue burden on individuals seeking abortion. This paper utilizes a feminist ethics lens by addressing issues that disproportionately impact women and considering ...

Protection Of Cells From Degeneration And Treatment Of Geographic Atrophy, Jayakrishna Ambati

Ophthalmology and Visual Science Faculty Patents

Therapeutic uses P2X₇ inhibition and inhibition of IRAK1 and/or IRAK4, methods protecting a cell, and screening methods for identifying inhibitors are described herein.

“That Pain Is Genuine To Them”: Provider Perspectives On Chronic Pain In University Student Populations, Alexandra C.H. Nowakowski, Kaitlyn E. Barningham, Charlyn D. Buford, Martin Laguerre, J. E. Sumerau

The Qualitative Report

We explored provider attitudes about and experiences in chronic pain management for university student populations. Our central question was: “What do providers at a large university campus health care center experience in the process of offering pain management services?” We explored instrumental, behavioral, emotional, and attitudinal dimensions of our participants’ experiences using a qualitative case study approach. Data were gathered through semi-structured interviews with 10 health care providers at the student health center for a large research university in Florida. Interviews captured providers’ background and experiences in providing pain management to student patients with diverse needs. We used grounded theory ...

Perceptions Of Athletes In Disabled And Non-Disabled Sport Contexts: A Descriptive Qualitative Research Study, Sheryl L. Chatfield, Michael Cottingham Ii

The Qualitative Report

The term supercrip suggests extraordinary feats but is sometimes applied to any proficiency demonstrated by an athlete with a disability. This use of the term potentially undermines spectator appreciation for achievements of the upper echelon of disability sports participants. Prior disability sport researchers have suggested that a comparison of individuals’ perceptions of athletic heroes with and without disabilities has potential to help disability sport marketers counter the supercrip stereotype. The purpose of this research was to explore differences in perceptions by comparing participant descriptions of role models with and without disabilities. Research participants, who consisted of undergraduate students at a ...

Age-Dependent Changes In The Articular Cartilage And Subchondral Bone Of C57bl/6 Mice After Surgical Destabilization Of Medial Meniscus, Henry Huang, Jordan D. Skelly, David C. Ayers, Jie Song

Jie Song

Age is the primary risk factor for osteoarthritis (OA), yet surgical OA mouse models such as destabilization of the medial meniscus (DMM) used for evaluating disease-modifying OA targets are frequently performed on young adult mice only. This study investigates how age affects cartilage and subchondral bone changes in mouse joints following DMM. DMM was performed on male C57BL/6 mice at 4 months (4 M), 12 months (12 M) and 19+ months (19 M+) and on females at 12 M and 18 M+. Two months after surgery, operated and unoperated contralateral knees were harvested and evaluated using cartilage histology scores ...

Crystal Structure Of Apobec3a Bound To Single-Stranded Dna Reveals Structural Basis For Cytidine Deamination And Specificity, Takahide Kouno, Tania V. Silvas, Brendan J. Hilbert, Shivender Shandilya, Markus-Frederik Bohn, Brian A. Kelch, William E. Royer, Mohan Somasundaran, Nese Kurt Yilmaz, Hiroshi Matsuo, Celia A. Schiffer

Celia A. Schiffer

Nucleic acid editing enzymes are essential components of the immune system that lethally mutate viral pathogens and somatically mutate immunoglobulins, and contribute to the diversification and lethality of cancers. Among these enzymes are the seven human APOBEC3 deoxycytidine deaminases, each with unique target sequence specificity and subcellular localization. While the enzymology and biological consequences have been extensively studied, the mechanism by which APOBEC3s recognize and edit DNA remains elusive. Here we present the crystal structure of a complex of a cytidine deaminase with ssDNA bound in the active site at 2.2 A. This structure not only visualizes the active ...