Classifying Complications: Assessing Adult Spinal Deformity 2-Year Surgical Outcomes., Eric O Klineberg, Peter G Passias, Gregory W Poorman, Cyrus M Jalai, Abiola Atanda, Nancy Worley, Samantha Horn, Daniel M Sciubba, D Kojo Hamilton, Douglas C Burton, Munish Chandra Gupta, Justin S Smith, Alexandra Soroceanu, Robert A Hart, Brian Neuman, Christopher P Ames, Frank J Schwab, Virginie Lafage

Articles, Abstracts, and Reports

STUDY DESIGN: Retrospective review of prospective database.

OBJECTIVE: Complication rates for adult spinal deformity (ASD) surgery vary widely because there is no accepted system for categorization. Our objective was to identify the impact of complication occurrence, minor-major complication, and Clavien-Dindo complication classification (Cc) on clinical variables and patient-reported outcomes.

METHODS: Complications in surgical ASD patients with complete baseline and 2-year data were considered intraoperatively, perioperatively (<6 >weeks), and postoperatively (>6 weeks). Primary outcome measures were complication timing and severity according to 3 scales: complication presence (yes/no), minor-major, and Cc score. Secondary outcomes were surgical outcomes (estimated blood loss [EBL], length ...

Imaging Data On Characterization Of Retinal Autofluorescent Lesions In A Mouse Model Of Juvenile Neuronal Ceroid Lipofuscinosis (Cln3 Disease), Qing Jun Wang, Kyung Sik Jung, Kabhilan Mohan, Mark E. Kleinman

Ophthalmology and Visual Science Faculty Publications

Juvenile neuronal ceroid lipofuscinosis (JNCL, aka. juvenile Batten disease or CLN3 disease), a lethal pediatric neurodegenerative disease without cure, often presents with vision impairment and characteristic ophthalmoscopic features including focal areas of hyper-autofluorescence. In the associated research article “Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium” (Zhong et al., 2020) [1], we reported ophthalmoscopic observations of focal autofluorescent lesions or puncta in the Cln3^Δex7/8 mouse retina at as young as 8 month old. In this data article, we performed differential interference contrast and confocal ...

The Impact Of The Deficit Reduction Act Of 2005 On The Length Of Hospital Stay, Honamattie Dabydeen

Dissertations and Theses

ABSTRACT

Introduction

Hospital-acquired infections (HAIs) are the most common complications of hospital care in the United States, and at least 1 in 10 patients admitted to the hospital will develop one. These unnecessary complications lead to about 99,000 premature deaths per year and add approximately $35–$45 billion of direct costs. Most of the cost increase is due to increases in hospital length of stay (LOS). This study examines the effect of a federal policy change on LOS among people with an HAI using the Donabedian quality of health care model as a framework. Specifically, this study examines the ...

Letters That Will Not Be Read, Kaila Pomeranz

Journal of Wellness

No abstract provided.

The World Pressed A Pause On Life, Cassandra Anonymous

Community Reflections

Class assignment HI 102 Western Civilization: Since 1500.

For many weeks I looked at the disadvantages that COVID-19 brought, and then I started seeing personal positives.

When Is This Going To Be Over?, Anonymous

Community Reflections

Assignment for the class Western Civilization.

For future generations, living life during this pandemic was having a perpetual thought of “when is this going to be over?” To look at life beforehand and not take anything for granted and live in the moment because one may never know when something drastic like a virus can change life in a blink of an eye.

Expect The Unexpected, Anonymous

Community Reflections

The content shows how Covid affected me and my family and what I want future generations to know.

Rho Gtpases: Big Players In Breast Cancer Initiation, Metastasis And Therapeutic Responses, Brock Humphries, Zhishan Wang, Chengfeng Yang

Toxicology and Cancer Biology Faculty Publications

Rho GTPases, a family of the Ras GTPase superfamily, are key regulators of the actin cytoskeleton. They were originally thought to primarily affect cell migration and invasion; however, recent advances in our understanding of the biology and function of Rho GTPases have demonstrated their diverse roles within the cell, including membrane trafficking, gene transcription, migration, invasion, adhesion, survival and growth. As these processes are critically involved in cancer initiation, metastasis and therapeutic responses, it is not surprising that studies have demonstrated important roles of Rho GTPases in cancer. Although the majority of data indicates an oncogenic role of Rho GTPases ...

Wellness In The Helping Professions: Historical Overview, Wellness Models, And Current Trends, Ashley J. Blount, Dalena L. Dillman Taylor, Glenn W. Lambie

Journal of Wellness

Introduction

Wellness and the concept of holism have rich histories throughout the helping professions. However, Westernized medical models often promote the concept of treatment rather than prevention, limiting the helper’s ability to focus on wellness when working with clients/patients. Therefore, in order to support a re-integration to holistic wellness and the prevention of illness, and re-focus on a wellness ideology, we conducted a thorough theoretical overview of wellness in the helping professions to: (a) provide a historical overview of wellness in helping professions, (b) discuss prominent wellness models, (c) review wellness assessments, (d) present wellness supervision models, and ...

Covid 19 Myocarditis: Myth Or Reality?, Lamyae Sasbou Md

Journal of the Saudi Heart Association

COVID 19 so far is not a known cardiotropic virus, and the term “myocarditis” should be exclusively used after EMB or autopsy proven diagnosis.

We report a case of 26-year-old man admitted for COVID 19 infection and symptoms leading to a myocarditis. We describe the workup that led to the potential diagnosis.

Diagnostic Accuracy Of Global Longitudinal Strain For Detecting Significant Coronary Artery Disease In Diabetic Patients Without Regional Wall Motion Abnormality, Oumaima Alaika, Souad Jamai, Nawal Doghmi, Mohamed Cherti

Journal of the Saudi Heart Association

Objectives:

Speckle-tracking imaging is a novel method for assessing left ventricular (LV) function and ischemic changes. The aim of this prospective study was to assess the diagnostic accuracy of global longitudinal strain (GLS) and regional longitudinal strain (RLS) parameters at rest in comparison to stress echocardiography findings for detecting significant coronary artery disease (CAD) in patients with diabetes mellitus (DM).

Methods:

We prospectively studied echocardiographic characteristics at rest with Speckle tracking echocardiography (2D STE) measures ; then stress echocardiography and coronary angiography data in 34 diabetic patients without regional wall motion abnormality (RWMA) at rest. Patients were grouped according to coronary ...

More Conscious Of The Things That I Value, Anonymous

Community Reflections

This document is a response to the question, "what would you like future generations to understand about what life was like during a pandemic?". My response talks about my personal experience with Covid-19 and how it has changed my life.

Primary Source Reflection 1: Covid-19 Pandemic Personal Experience, Kaitlyn Anonymous

Community Reflections

Class assignment HI 102 Western Civilization: Since 1500.

My document incapsulates my personal experience of first learning about the pandemic, and contracting COVID.

Journal Club - Dapa-Hf Trial, Emma De Louw, Pgy-3

Department of Family & Community Medicine Presentations and Grand Rounds

No abstract provided.

Isolation And Quarantine, Anonymous

Community Reflections

My Covid experience talks about the day we were moved out to the present.

Quarantining At Home, Anonymous

Community Reflections

What it was like quarantining at home and how it felt living through the pandemic.

This Pandemic Drastically Affected My Life, David Creo

Community Reflections

Class assignment for Western Civilization, Professor Marino.

The coronavirus entered the United States and started to rapidly spread, forcing my high school to indefinitely suspend and eventually cancel my whole senior year and all activities included, which would totally ruin my whole year, and the worst part was that this was completely unexpected.

This Virus Is Not Going Away, Anonymous

Community Reflections

Living during the COVID-19 pandemic was nothing short of infuriating. If there is anything I have learned about America, it is that some people are extremely selfish.

As Soon As This Is All Over, I Am Going Back To Paris, Anonymous

Community Reflections

My plans for 2020 were much different from how it actually played out. I had plans to study abroad, turn 21, and start my senior year of college. I never expected a worldwide pandemic to ruin it all.

Neutrophil: A New Player In Metastatic Cancers, Mengyue Wu, Mutian Ma, Zhenya Tan, Hong Zheng, Xia Liu

Toxicology and Cancer Biology Faculty Publications

The interaction between cancer cells and immune cells is important for the cancer development. However, much attention has been given to T cells and macrophages. Being the most abundant leukocytes in the blood, the functions of neutrophils in cancer have been underdetermined. They have long been considered an “audience” in the development of cancer. However, emerging evidence indicate that neutrophils are a heterogeneous population with plasticity, and subpopulation of neutrophils (such as low density neutrophils, polymorphonuclear-myeloid-derived suppressor cells) are actively involved in cancer growth and metastasis. Here, we review the current understanding of the role of neutrophils in cancer development ...