Project Renew Worcester, 2018 Clark University
Project Renew Worcester, Danni Yue, Amy Zhang, Jing Han, Omid Ashrafi, Yiming Xu
School of Professional Studies
n The client for this capstone project is RENEW Worcester which is a fledgling solar power project whose main goals are to bring renewable energy in the form of solar power into local, primarily low-income communities and are committed to the mission of making the transition off of fossil fuels to clean, renewable power. Based in Worcester, Massachusetts, they are a local chapter of Co-op Power which is a consumer-owned sustainable energy cooperative (co-op) made up of numerous different local chapters all over the New England area as well as the state of New York. The problem that we will ...
Virulence Regulation In Pseudomonas Aeruginosa Via The Alginate Regulators, Algu And Algr, The Posttranscriptional Regulator, Rsma, And The Two-Component System, Algz/R, 2018 East Tennessee State Universtiy
Virulence Regulation In Pseudomonas Aeruginosa Via The Alginate Regulators, Algu And Algr, The Posttranscriptional Regulator, Rsma, And The Two-Component System, Algz/R, Sean Stacey
Electronic Theses and Dissertations
Pseudomonas aeruginosa is a Gram-negative bacillus able to colonize a wide variety of environments. In the human host, P. aeruginosa can establish an acute infection or persist and create a chronic infection. P. aeruginosa is able to establish a niche and persist in human hosts by using a wide array of virulence factors used for: movement, killing host cells, and evading immune cells and antibiotics. Understanding virulence factors and their regulation has proved to be an important means of combating the morbidity and mortality of P. aeruginosa as well as the ever-increasing threat of drug resistance. By targeting virulence factors ...
Removal Of Carbamazepine From Drinking Water, 2018 University of Arkansas, Fayetteville
Removal Of Carbamazepine From Drinking Water, Thomas Krumpolc, Juan Rodriguez, Jordan Alex Gadberry, Zach Wiese, Paola Marrero-Rivera, Adam Johnson
Chemical Engineering Undergraduate Honors Theses
Due to the increasing prevalence of prescription medication over the past few decades, pharmaceuticals have accumulated in various water sources. This has become a public health concern because many pharmaceuticals have limited research on the effects of chronic low-level exposure. According to the World’s Health Organization (WHO), traces of pharmaceuticals products have been reported in different water sources such as surface waters, wastewater, groundwater, and drinking water. One pharmaceutical of interest that has been detected in water sources is carbamazepine. Carbamazepine (CBZ) is a common pharmaceutical prescribed for the treatment of seizure disorders, neuropathic pain, and various psychological ...
Developing Cultural Competency In Anesthesia Through Student Registered Nurse Anesthetists, 2018 University of Southern Mississippi
Developing Cultural Competency In Anesthesia Through Student Registered Nurse Anesthetists, Emma To
Certified Registered Nurse Anesthetists (CRNAs) are the main anesthesia providers in over 70% of rural hospitals providing anesthesia. Each year, over 2,000 student registered nurse anesthetists (SRNAs) graduate and continue as licensed CRNAs. This Doctor of Nurse Practice (DNP) project emphasizes the importance of developing culturally competent providers in anesthesia by promoting early outreach in cultural competence education of SRNAs. Cultural competence is described as possessing characteristics of congruent attitudes, awareness, and conduct that provides and enables effective skills in cross-cultural encounters. Encompassing cultural competency education early in the SRNAs profession may provide valuable lifelong cultural skills that will ...
Hypothalamic Circuits In The Control Of Feeding And Emotional Behaviors, 2018 The University of Texas M D Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences
Hypothalamic Circuits In The Control Of Feeding And Emotional Behaviors, Leandra Mangieri
UT GSBS Dissertations and Theses (Open Access)
Feeding results from the integration of both nutritional and affective states, and is guided by complex neural circuitry in the brain. The hypothalamus is a critical center controlling feeding and motivated behaviors. We found that targeted photostimulation of projections from the lateral hypothalamus (LH) to the paraventricular hypothalamus (PVH) in mice elicited voracious feeding and repetitive self-grooming behavior. GABA neurotransmission in the LH->PVH circuit mediated the evoked feeding behavior, and elicited behavioral approach, whereas glutamate release promoted repetitive self-grooming, which was stress-related in nature. Optogenetic inhibition of LHGABA ->PVH circuit reduced feeding after fasting, whereas photostimulation abruptly stopped ...
Nkx2-1-As1 Negatively Regulates Cd274/Pd-L1, Cell-Cell Interaction Genes, And Limits Human Lung Carcinoma Cell Migration., 2018 Boston University School of Medicine
Nkx2-1-As1 Negatively Regulates Cd274/Pd-L1, Cell-Cell Interaction Genes, And Limits Human Lung Carcinoma Cell Migration., Hasmeena Kathuria, Guetchyn Millien, Liam Mcnally, Adam C. Gower, Jean-Bosco Tagne, Yuxia Cao, Maria I. Ramirez
Center for Translational Medicine Faculty Papers
The function of most long noncoding RNAs (lncRNAs) is unknown. However, recent studies reveal important roles of lncRNAs in regulating cancer-related pathways. Human antisense lncRNA-NKX2-1-AS1 partially overlaps the NKX2-1/TTF1 gene within chromosomal region 14q13.3. Amplification of this region and/or differential expression of genes therein are associated with cancer progression. Herein we show higher levels of NKX2-AS1 and NKX2-1 in lung adenocarcinomas relative to non-tumor controls but no correlation between NKX2-1-AS1 and NKX2-1 levels across specimens, or with amplification of the 14q13.3 region, suggesting that NKX2-1-AS1 and NKX2-1 are independently regulated. Loss-and-gain of function experiments showed that ...
Phr: Patient Health Record, 2018 University of Nebraska at Omaha
Phr: Patient Health Record, Quinn Nelson
The rapid development of information technology systems has expanded into multiple disciplines and results in systems that are limited by initial design and implementation: the Healthcare Information Technology (HIT) space is no different. The introduction of the Electronic Health Record (EHR) system has changed the way healthcare operates. Initial designs of these systems were focused on serving the needs of insurance companies and healthcare billing departments. Research shows that the design of EHR systems negatively impact provider-patient interactions and the care they receive. This capstone project capitalizes on the collaboration efforts between UNO and UNMC – by joining a research group ...
Reducing Thirty-Day Hospital Readmissions In Drug And Medication Poisoning: An Observational Study, 2018 Seton Hall University
Reducing Thirty-Day Hospital Readmissions In Drug And Medication Poisoning: An Observational Study, Jenna M. Evans
Seton Hall University Dissertations and Theses (ETDs)
A common and costly occurrence in the United States is thirty-day hospital readmissions. Awareness of 30-day hospital readmissions is currently a national priority. To reduce avoidable readmissions, the Patient Protection and Affordable Care Act of 2010 established a “Hospital Readmission Reduction Program” implemented to provide possible solutions for preventable thirty-day readmissions. Part of this policy states that hospitals with higher than expected adjusted re-hospitalization rates have lower reimbursement rates. One specific area known to be a cause of thirty-day hospital readmissions is drug and medication poisoning. An observational study of data from the Nationwide Readmissions Database is being used to ...
Exploring The Moderating Effect Of Cognitive Autonomy On The Relationship Between Cognitive Distortions And Youth’S Externalizing Behaviors, Liam J. Fischback
All Graduate Theses and Dissertations
Scholars have connected cognitive distortions to adolescents’ externalizing behaviors. Other scholars have offered that higher levels of cognitive autonomy, which develops during adolescence, may be a protective factor for problem behaviors in adolescence. To date, no studies have explored how these two cognitive processes function and potentially interact to predict adolescent problem behaviors. This study’s purpose was to see if cognitive autonomy affected the relationship between cognitive distortions and externalizing behaviors in a clinical population of adolescents. Past research has suggested that cognitive distortions are greater and more prevalent in clinical populations. Because of this, the processes of cognitive ...
A Learning Community Approach To Identifying Interventions In Health Systems To Reduce Colorectal Cancer Screening Disparities., 2018 Thomas Jefferson University
A Learning Community Approach To Identifying Interventions In Health Systems To Reduce Colorectal Cancer Screening Disparities., Lillian C. Man, Melissa Dicarlo, Emily Lambert, Randa Sifri, Martha Romney, Linda Fleisher, Ronald Myers
Department of Medical Oncology Faculty Papers
Although colorectal cancer (CRC) screening in the United States has been increasing, screening rates are not optimal, and there are persistent disparities in CRC screening and mortality, particularly among minority patients. As most CRC screening takes place in primary care, health systems are well-positioned to address this important population health problem. However, most health systems have not actively engaged in identifying and implementing effective evidence-based intervention strategies that can raise CRC screening rates and reduce disparities. Drawing on the Collective Impact Model and the Interactive Systems Framework for Dissemination and Implementation, our project team applied a learning community strategy to ...
Effect Of Differences In Metabolic Activity Of Melanoma Models On Response To Lonidamine Plus Doxorubicin., 2018 University of Pennsylvania
Effect Of Differences In Metabolic Activity Of Melanoma Models On Response To Lonidamine Plus Doxorubicin., Kavindra Nath, Jeffrey Roman, David S. Nelson, Lili Guo, Seung-Cheol Lee, Stepan Orlovskiy, Kevin Muriuki, Daniel F. Heitjan, Stephen Pickup, Dennis B. Leeper, Ian A. Blair, Mary E. Putt, Jerry D. Glickson
Department of Radiation Oncology Faculty Papers
Lonidamine (LND), a metabolic modulator, sensitizes DB-1 human melanoma to doxorubicin (DOX) chemotherapy by acidifying and de-energizing the tumor. This report compares the effects of LND on two human melanoma lines, DB-1 and WM983B, which exhibit different metabolic properties. Using liquid chromatography mass spectrometry and Seahorse analysis, we show that DB-1 was more glycolytic than WM983B in vitro. 31P magnetic resonance spectroscopy (MRS) indicates that LND (100 mg/kg, i.p.) induces similar selective acidification and de-energization of WM983B xenografts in immunosuppressed mice. Over three hours, intracellular pH (pHi) of WM983B decreased from 6.91 ± 0.03 to 6 ...
Magnitude And Impact Of Multiple Chronic Conditions With Advancing Age In Older Adults Hospitalized With Acute Myocardial Infarction, 2018 University of Massachusetts Medical School
Magnitude And Impact Of Multiple Chronic Conditions With Advancing Age In Older Adults Hospitalized With Acute Myocardial Infarction, Mayra Tisminetzky, Hoa L. Nguyen, Jerry H. Gurwitz, David D. Mcmanus, Joel M. Gore, Sonal Singh, Jorge L. Yarzebski, Robert J. Goldberg
Open Access Articles
BACKGROUND: To examine age-specific differences in the frequency and impact of cardiac and non-cardiac conditions among patients aged 65years and older hospitalized with acute myocardial infarction (AMI).
METHODS: Study population consisted of 3863 adults hospitalized with AMI at 11 medical centers in central Massachusetts on a biennial basis between 2001 and 2011. The presence of 11 chronic conditions (five cardiac and six non-cardiac) was based on the review of hospital medical records.
RESULTS: Participants' median age was 79years, 49% were men, and had an average of three chronic conditions (average of cardiac conditions: 2.6 and average of non-cardiac conditions ...
Medial Temporal Lobe Functional Connectivity Predicts Stimulation-Induced Theta Power., 2018 University of Pennsylvania
Medial Temporal Lobe Functional Connectivity Predicts Stimulation-Induced Theta Power., E. A. Solomon, J. E. Kragel, R. Gross, B. Lega, M. R. Sperling, G. Worrell, S. A. Sheth, K. A. Zaghloul, B. C. Jobst, J. M. Stein, S. Das, R. Gorniak, C. S. Inman, S. Seger, D. S. Rizzuto, M. J. Kahana
Department of Neurology Faculty Papers
Focal electrical stimulation of the brain incites a cascade of neural activity that propagates from the stimulated region to both nearby and remote areas, offering the potential to control the activity of brain networks. Understanding how exogenous electrical signals perturb such networks in humans is key to its clinical translation. To investigate this, we applied electrical stimulation to subregions of the medial temporal lobe in 26 neurosurgical patients fitted with indwelling electrodes. Networks of low-frequency (5-13 Hz) spectral coherence predicted stimulation-evoked increases in theta (5-8 Hz) power, particularly when stimulation was applied in or adjacent to white matter. Stimulation tended ...
The Study Of Alcoholic Liver Diseases, 2018 East Tennessee State University
The Study Of Alcoholic Liver Diseases, Seun Emmanuel Owoseni
Electronic Theses and Dissertations
Excessive alcohol consumption is the primary contributing factor in the development of alcoholic liver diseases (ALD). Nicotine contained in tobacco is a major addictive alkaloid, which enhances the effects of ALDs. The major enzyme involved in nicotine metabolism is cytochrome P450 2A5 (CYP2A5) which is produced in the liver. Alcohol can stimulate the CYP2A5 enzyme. We utilized cyp2a5-/- knockout mice in this research to examine the effects of CYP2A5.
The cyp2a5-/- mice and wild-type (WT) mice were fed liquid ethanol diet with or without nicotine to induce ALD. Nicotine enhancing effects on ALD were observed in WT mice but not ...
Penirum Asli.Jpg, 2018 Golden Gate University School of Law
Penirum Asli.Jpg, Dewi Jum
Animal-Assisted Interventions For Children With Autism Spectrum Disorders: A Survey Of French Facilities, 2018 Clinique vétérinaire Saint Antoine, Chesnay; École Nationale Vétérinaire de Toulouse
Animal-Assisted Interventions For Children With Autism Spectrum Disorders: A Survey Of French Facilities, Claire Philippe-Peyroutet, Marine Grandgeorge
People and Animals: The International Journal of Research and Practice
Our survey of animal-assisted interventions (AAI) offered by French intervention facilities aimed to examine and describe the range of AAI for autism spectrum disorder (ASD) children. We invited 2,302 facilities to reply to an online questionnaire. The responses to our survey (n = 386) revealed that animals were used extensively as a complementary intervention. Most AAI sessions were in groups. Various animal species (especially horses and dogs) and facility staff members as well as external collaborators were involved. Numerous benefits (e.g., enhanced well-being, self-esteem, and socialization) were reported. Facilities face difficulties in connection with AAI including finances, staffing, and ...
Assessment Of Recent Cases Of Animal Hoarding In Germany: The Challenge For Animal Shelters And Public Authorities, 2018 German Animal Welfare Association (Deutscher Tierschutzbund e.V.), Animal Welfare Academy
Assessment Of Recent Cases Of Animal Hoarding In Germany: The Challenge For Animal Shelters And Public Authorities, Sophie Arnold, Henriette Mackensen, Evelyn Ofensberger, Brigitte Rusche
People and Animals: The International Journal of Research and Practice
Animal hoarding is a severe problem in the field of human-animal interaction. The goal of this study was to assess the current situation of animal hoarding in Germany. Reports of animal hoarding cases were collected from animal shelters and public media between January 2012 and December 2015; 120 cases were analyzed. A total of 9,174 animals were hoarded during the investigated time period. The results showed that cases involving cats were most common, followed by cases involving dogs and small mammals. The average number (x¯) of animals hoarded per case was 76 (x˜ = 43). Small mammals were hoarded in ...
Grab Cheapest Kamagra Oral Jelly Only At Sureviagra.Com, 2018 Bryant University
Grab Cheapest Kamagra Oral Jelly Only At Sureviagra.Com, Tisa Smith
Kulit Gatal Berair Dan Perih, 2018 Bryant University
Kulit Gatal Berair Dan Perih, Gatal Yang Merambat
Gatal Yang Merambat
Kulit Melepuh Dan Gatal, 2018 Bryant University