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225,740 full-text articles. Page 1381 of 8641.

Carbapenemase Producing Klebsiella Pneumoniae (Kpc) Meningitis From Chronic Otitis Media, S. Anwar, S. Acharya, S. Thapa, J. Rabadi, N. Mobarakai 2020 Northwell Health

Carbapenemase Producing Klebsiella Pneumoniae (Kpc) Meningitis From Chronic Otitis Media, S. Anwar, S. Acharya, S. Thapa, J. Rabadi, N. Mobarakai

Journal Articles

© 2020 The Authors Meningitis and brain abscess caused by carbapenemase-producing Klebsiella pneumoniae (KPC) is rarely described in the medical literature. Such infections have been described after neurosurgical medium or post-trauma. We describe an unusual case of KPC meningitis originating from with long term intravenous antibiotics.


Life Threatening Haemoptysis In Primary Lung Cancer-Signet Ring Cell Carcinoma, S. Anwar, S. Acharya, D. Elsayegh, A. Sokoloff, M. Rehan 2020 Northwell Health

Life Threatening Haemoptysis In Primary Lung Cancer-Signet Ring Cell Carcinoma, S. Anwar, S. Acharya, D. Elsayegh, A. Sokoloff, M. Rehan

Journal Articles

© 2020 The Author(s) Primary signet ring cell carcinoma of the lung is a rare non-small cell carcinoma of the lung with extremely aggressive features and poor prognosis. The diagnosis mainly required tissue biopsy with immunohistochemical analysis and gene mutation studies. We describe a unique case of primary signet ring cell carcinoma of the lung presenting with life threatening haemoptysis along with literature review of prognosis and management of this rare clinical entity.


Lung Nodule Management Practice Patterns - A Survey Of Indian Physicians, V. Mehta, P. Makkar, K. Bhatia, S. Mehta, S. Raoof 2020 Zucker School of Medicine at Hofstra/Northwell

Lung Nodule Management Practice Patterns - A Survey Of Indian Physicians, V. Mehta, P. Makkar, K. Bhatia, S. Mehta, S. Raoof

Journal Articles

No abstract provided.


Effect Of Direct Oral Anticoagulant, Patient, And Surgery Characteristics On Clinical Outcomes In The Perioperative Anticoagulation Use For Surgery Evaluation Study., K. MacDougall, J. D. Douketis, N. Li, N. P. Clark, A. Tafur, J. D'Astous, J. Duncan, S. Schulman, A. C. Spyropoulos 2020 Northwell Health

Effect Of Direct Oral Anticoagulant, Patient, And Surgery Characteristics On Clinical Outcomes In The Perioperative Anticoagulation Use For Surgery Evaluation Study., K. Macdougall, J. D. Douketis, N. Li, N. P. Clark, A. Tafur, J. D'Astous, J. Duncan, S. Schulman, A. C. Spyropoulos

Journal Articles

Introduction  The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) Study assessed a standardized perioperative management strategy in patients with atrial fibrillation who were taking a direct oral anticoagulant (DOAC) and required an elective surgery or procedure. The aim of this substudy is to analyze the safety of this management strategy across different patient subgroups, according to four presurgical variables: (1) DOAC type and dose, (2) surgery/procedure bleed risk, (3) patient renal function, and (4) age. Methods  Clinical outcomes analyzed included major bleeding (MB), arterial thromboembolism, any bleeding, and any thromboembolism. We used descriptive statistics to summarize clinical outcomes, where ...


Erratum: A Large Right Ventricle And Severe Hypoxemia. Use Of Bedside Transesophageal Echocardiography To Assess Cardiopulmonary Failure (Annals Of The American Thoracic Society (2020) 17 (112-115) Doi: 10.1513/Annalsats.201904-316cc), A. Agrawal, M. Frank, A. Tsegaye 2020 Northwell Health

Erratum: A Large Right Ventricle And Severe Hypoxemia. Use Of Bedside Transesophageal Echocardiography To Assess Cardiopulmonary Failure (Annals Of The American Thoracic Society (2020) 17 (112-115) Doi: 10.1513/Annalsats.201904-316cc), A. Agrawal, M. Frank, A. Tsegaye

Journal Articles

Copyright © 2020 by the American Thoracic Society. The authors would like to make a correction to the legends of Videos 1 and 3 in their article published in the January 2020 issue of AnnalsATS (1). The definition for the abbreviation TEE in these video legends should read "transesophageal echocardiogram." For the convenience of our readers, AnnalsATS is replacing the online version of the article with a corrected version; we apologize for the error.


Outcomes Of Liver Transplant Recipients With Acute-On-Chronic Liver Failure Based On Easl-Clif Consortium Definition: A Single-Center Study, U. Agbim, A. Sharma, B. Maliakkal, S. Karri, M. Yazawa, W. Goldkamp, P. S. Podila, J. M. Vanatta, H. Gonzalez, S. K. Satapathy, +3 additional authors 2020 Zucker School of Medicine at Hofstra/Northwell

Outcomes Of Liver Transplant Recipients With Acute-On-Chronic Liver Failure Based On Easl-Clif Consortium Definition: A Single-Center Study, U. Agbim, A. Sharma, B. Maliakkal, S. Karri, M. Yazawa, W. Goldkamp, P. S. Podila, J. M. Vanatta, H. Gonzalez, S. K. Satapathy, +3 Additional Authors

Journal Articles

© 2020 Cambridge University Press. All rights reserved. Background. The impact of acute-on-chronic liver failure (ACLF) defined by European Association for the Study of the Liver-Chronic Liver Failure in liver transplant (LT) recipients has not been well characterized. The aim of the study was to assess early posttransplant morbidity and survival of ACLF patients. Methods. Eight hundred twenty-five consecutive LT patients (04/2006-03/2013) were included in a retrospective analysis. Of the 690 evaluable patients, 589 had no ACLF, and the remaining 101 were grouped into ACLF Grades 1-3 (ACLF Grade 1: 50 [49.5%], ACLF Grade 2: 32 [31.7 ...


Optimizing Tissue Use: A Step-Wise Approach To Diagnosing Squamous Cell Lung Carcinoma On Small Biopsies, C. Olazagasti, I. Preeshagul, M. Aziz, N. Seetharamu 2020 Northwell Health

Optimizing Tissue Use: A Step-Wise Approach To Diagnosing Squamous Cell Lung Carcinoma On Small Biopsies, C. Olazagasti, I. Preeshagul, M. Aziz, N. Seetharamu

Journal Articles

© The Author(s) 2020. Background: Histologic subtyping of lung cancer has significant implications for treatment planning. Accurate diagnosis based on cytology/small biopsy specimens is challenging and frequently determined by morphology, as material is often not sufficient for immunohistochemical studies (IHC). We investigated the concordance between the rates of diagnosis from cytology/small biopsies compared with surgical specimens in patients with squamous cell lung cancer (SCC) and the utility of IHC for diagnostic precision in lung cancer subtyping. Methods: We conducted a 5-year retrospective analysis identifying cases of SCC diagnosed on cytology/small biopsies ± IHC and compared them with subsequent ...


The Course Of Sars-Cov2 Infection Was Not Severe In A Crohn's Patient Who Administered Maintenance Anti-Tnf Therapy Overlapping The Early Pre-Symptomatic Period Of Infection., F. Okeke, A. Mone, A. Swaminath 2020 Northwell Health

The Course Of Sars-Cov2 Infection Was Not Severe In A Crohn's Patient Who Administered Maintenance Anti-Tnf Therapy Overlapping The Early Pre-Symptomatic Period Of Infection., F. Okeke, A. Mone, A. Swaminath

Journal Articles

The Inflammatory Bowel Disease (IBD) population, which may require treatment with immunosuppressive medications, may be uniquely vulnerable to COVID-19 infection. In fact, there is some evidence these medications may inhibit the cytokine storm that is theorized to cause a rapid decline seen in COVID-19. In addition, the digestive symptoms of COVID-19 can be difficult to distinguish from the activation of IBD. We present an interesting case of a Crohn's patient inadvertently administering anti-cytokine therapy during the pre-symptomatic period of COVID-19 infection. Immune suppression during early infection with SARS-COV2 risks a poor immune response to the virus and could theoretically ...


Nafld Epidemiology, Emerging Pharmacotherapy, Liver Transplantation Implications And The Trends In The United States, C. Gadiparthi, M. Spatz, S. Greenberg, U. Iqbal, S. Kanna, S. K. Satapathy, A. Broder, A. Ahmed 2020 Zucker School of Medicine at Hofstra/Northwell

Nafld Epidemiology, Emerging Pharmacotherapy, Liver Transplantation Implications And The Trends In The United States, C. Gadiparthi, M. Spatz, S. Greenberg, U. Iqbal, S. Kanna, S. K. Satapathy, A. Broder, A. Ahmed

Journal Articles

© 2020 Authors. Nonalcoholic fatty liver disease (NAFLD) is a hepatic mani-festation of metabolic syndrome. The spread of obesity worldwide in pandemic proportions has led to a rapid rise of NAFLD in developed and developing countries alike. There are no approved pharmacological agents to treat steatohepatitis or advanced fibrosis but obeticholic acid recently has shown some promise in phase III trial. Currently, NAFLD is the number one etiology for simultaneous liver and kidney transplantation in the USA, second most common indication for liver transplantation (LT) and projected to become number one very soon. LT for NAFLD poses unique challenges, as these ...


Longitudinal Renal Function In Liver Transplant Recipients With Acute-On-Chronic Liver Failure, M. Yazawa, B. Maliakkal, S. Nair, P. S. Podila, U. A. Agbim, S. Karri, S. D. Khan, D. Maluf, J. D. Eason, S. K. Satapathy, +1 additional author 2020 Zucker School of Medicine at Hofstra/Northwell

Longitudinal Renal Function In Liver Transplant Recipients With Acute-On-Chronic Liver Failure, M. Yazawa, B. Maliakkal, S. Nair, P. S. Podila, U. A. Agbim, S. Karri, S. D. Khan, D. Maluf, J. D. Eason, S. K. Satapathy, +1 Additional Author

Journal Articles

No abstract provided.


Roth Net-Assisted Endoscopic-Guided Manometry Catheter Placement., D. Gurala, J. Philipose, A. D. Polavarapu, Y. El Douaihy, S. M. Mulrooney 2020 Northwell Health

Roth Net-Assisted Endoscopic-Guided Manometry Catheter Placement., D. Gurala, J. Philipose, A. D. Polavarapu, Y. El Douaihy, S. M. Mulrooney

Journal Articles

High-resolution esophageal manometry (HRM) has become the gold standard to diagnose esophageal motility disorders. Usually, this procedure is performed by introducing the catheter, which has pressure sensors, into the esophagus and proximal stomach via the nares. Repeated coiling of the catheter and inability to pass through the gastroesophageal junction (GEJ) are common challenges encountered. Endoscopy-guided placement of the catheter can overcome these difficulties. However, sometimes even with the use of endoscopy, it is difficult to advance catheter due to anatomical variants. The extreme fragility of the catheter and sensors and the high cost of this reusable device precludes the use ...


Erysipelothrix Rhusiopathiae Endocarditis, T. Wang, D. Khan, N. Mobarakai 2020 Northwell Health

Erysipelothrix Rhusiopathiae Endocarditis, T. Wang, D. Khan, N. Mobarakai

Journal Articles

© 2020 Erysipelothrix rhusiopathiae is a zoonotic gram positive coccobacillus. It is rarely found in humans as an occupational pathogen that mainly infects animal handlers. There are three forms of human infection: localized erysipeloid, diffuse cutaneous form and lastly, bacteremia that could progress to infective endocarditis. We present a case of a 59-year-old male who was found to have E. rhusiopathiae bacteremia that was diagnosed as aortic valve endocarditis with severe aortic regurgitation. The patient was treated with ampicillin-sulbactam then transitioned to six weeks of intravenous ampicillin. This report summarizes a rare organism that causes a serious human infection and discusses ...


A Randomized,Double-Blind,Placebo-Controlled, Phaseiistudy Of Regorafenib Versus Placebo In Advanced/Metastatic,Treatment-Refractoryliposarcoma: Results From Thesarc024study, R. F. Riedel, K. Ballman, Y. Lu, S. Attia, E. T. Loggers, K. N. Ganjoo, M. B. Livingston, W. Chow, J. Wright, R. G. Maki, +10 additional authors 2020 Zucker School of Medicine at Hofstra/Northwell

A Randomized,Double-Blind,Placebo-Controlled, Phaseiistudy Of Regorafenib Versus Placebo In Advanced/Metastatic,Treatment-Refractoryliposarcoma: Results From Thesarc024study, R. F. Riedel, K. Ballman, Y. Lu, S. Attia, E. T. Loggers, K. N. Ganjoo, M. B. Livingston, W. Chow, J. Wright, R. G. Maki, +10 Additional Authors

Journal Articles

No abstract provided.


Polycystic Ovary Syndrome And Gender Identity, M. Liu, S. Murthi, L. Poretsky 2020 Zucker School of Medicine at Hofstra/Northwell

Polycystic Ovary Syndrome And Gender Identity, M. Liu, S. Murthi, L. Poretsky

Journal Articles

No abstract provided.


Impact Of Idelalisib On Health-Related Quality Of Life In Patients With Relapsed Chronic Lymphocytic Leukemia In A Phase Iii Randomized Trial, P. Ghia, S. E. Coutre, B. D. Cheson, J. C. Barrientos, P. Hillmen, A. R. Pettitt, A. D. Zelenetz, S. Shreay, M. Hallek, R. R. Furman 2020 Zucker School of Medicine at Hofstra/Northwell

Impact Of Idelalisib On Health-Related Quality Of Life In Patients With Relapsed Chronic Lymphocytic Leukemia In A Phase Iii Randomized Trial, P. Ghia, S. E. Coutre, B. D. Cheson, J. C. Barrientos, P. Hillmen, A. R. Pettitt, A. D. Zelenetz, S. Shreay, M. Hallek, R. R. Furman

Journal Articles

No abstract provided.


Predictors Of Preprocedural Direct Oral Anticoagulant Levels In Patients Having An Elective Surgery Or Procedure, J. R. Shaw, N. Li, T. Vanassche, M. Coppens, A. C. Spyropoulos, S. Syed, M. Radwi, J. Duncan, S. Schulman, J. D. Douketis 2020 Zucker School of Medicine at Hofstra/Northwell

Predictors Of Preprocedural Direct Oral Anticoagulant Levels In Patients Having An Elective Surgery Or Procedure, J. R. Shaw, N. Li, T. Vanassche, M. Coppens, A. C. Spyropoulos, S. Syed, M. Radwi, J. Duncan, S. Schulman, J. D. Douketis

Journal Articles

No abstract provided.


Ibrutinib Restores Immune Cell Numbers And Function In First-Line And Relapsed/Refractory Chronic Lymphocytic Leukemia, I. G. Solman, L. K. Blum, H. Y. Hoh, T. J. Kipps, J. A. Burger, J. C. Barrientos, S. O'Brien, S. P. Mulligan, N. E. Kay, A. Mongan, +4 additional authors 2020 Zucker School of Medicine at Hofstra/Northwell

Ibrutinib Restores Immune Cell Numbers And Function In First-Line And Relapsed/Refractory Chronic Lymphocytic Leukemia, I. G. Solman, L. K. Blum, H. Y. Hoh, T. J. Kipps, J. A. Burger, J. C. Barrientos, S. O'Brien, S. P. Mulligan, N. E. Kay, A. Mongan, +4 Additional Authors

Journal Articles

© 2020 The Authors Ibrutinib positively modulates many T-cell subsets in chronic lymphocytic leukemia (CLL). To understand ibrutinib's effects on the broader landscape of immune cell populations, we comprehensively characterized changes in circulating counts of 21 immune blood cell subsets throughout the first year of treatment in patients with relapsed/refractory (R/R) CLL (n = 55, RESONATE) and previously untreated CLL (n = 50, RESONATE-2) compared with untreated age-matched healthy donors (n = 20). Ibrutinib normalized abnormal immune cell counts to levels similar to those of age-matched healthy donors. Ibrutinib significantly decreased pathologically high circulating B cells, regulatory T cells, effector/memory ...


Atypical Presentation Of Panhypopituitarism., H. K. Rai, G. John, M. Anton 2020 Zucker School of Medicine at Hofstra/Northwell

Atypical Presentation Of Panhypopituitarism., H. K. Rai, G. John, M. Anton

Journal Articles

Hypopituitarism is a rare disorder. Hypopituitarism can present as a deficiency of individual anterior pituitary hormones (e.g., adrenocorticotropic hormone, thyroid-stimulating hormone, luteinizing hormone, follicle-stimulating hormone, prolactin, growth hormone) or posterior pituitary hormones (e.g., oxytocin, vasopressin) or as the deficiency of all these pituitary hormones, also known as panhypopituitarism. Here, we discuss a 59-year-old man who presented with two episodes of unwitnessed syncope after an episode of vomiting. On admission, the patient was hypotensive to 88/54 mmHg, afebrile, and with a leukocyte count of 21.43 K/µL (reference range: 3.80 to 10.50 K/µL). CT ...


Predictors Of Bleeding In The Perioperative Anticoagulant Use For Surgery Evaluation Study, A. J. Tafur, N. P. Clark, A. C. Spyropoulos, N. Li, E. Kaplovitch, K. MacDougall, S. Schulman, J. A. Caprini, J. Douketis 2020 Zucker School of Medicine at Hofstra/Northwell

Predictors Of Bleeding In The Perioperative Anticoagulant Use For Surgery Evaluation Study, A. J. Tafur, N. P. Clark, A. C. Spyropoulos, N. Li, E. Kaplovitch, K. Macdougall, S. Schulman, J. A. Caprini, J. Douketis

Journal Articles

No abstract provided.


Pneumothorax In Covid-19 Acute Respiratory Distress Syndrome: Case Series., K. Wong, D. H. Kim, A. Iakovou, S. Khanijo, A. Tsegaye, S. Hahn, M. Narasimhan, G. Zaidi 2020 Zucker School of Medicine at Hofstra/Northwell

Pneumothorax In Covid-19 Acute Respiratory Distress Syndrome: Case Series., K. Wong, D. H. Kim, A. Iakovou, S. Khanijo, A. Tsegaye, S. Hahn, M. Narasimhan, G. Zaidi

Journal Articles

Objective The study aims to describe the clinical characteristics and outcomes of patients with COVID-19 related acute respiratory distress syndrome (ARDS) who developed pneumothorax. Design and setting A retrospective chart review was performed of the electronic medical record. Patients were included if they were identified as having confirmed COVID-19 as well as pneumothorax from March 16, 2020 to May 31, 2020. Patients' demographic and clinical characteristics, mechanical ventilator parameters, lung compliance measurements and outcomes during hospitalization were collected. This case series was conducted in intensive care units at two large tertiary care centers within the Northwell Health System, located in ...


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