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The Learners' Perspective On Internal Medicine Ward Rounds: A Cross-Sectional Study, M. Tariq, Afaq Motiwala, Syed Umer Ali, Mehmood Riaz, Safia Awan, Jaweed Akhter 2010 Aga Khan University

The Learners' Perspective On Internal Medicine Ward Rounds: A Cross-Sectional Study, M. Tariq, Afaq Motiwala, Syed Umer Ali, Mehmood Riaz, Safia Awan, Jaweed Akhter

Department of Medicine

Background: Ward rounds form an integral part of Internal Medicine teaching. This study aimed to determine the trainees' opinions regarding various aspects of their ward rounds, including how well they cover their learning needs, how they would like the rounds to be conducted, and differences of opinion between medical students and postgraduates. Methods: A cross-sectional study was conducted on a total of 134 trainees in Internal Medicine, comprising medical students, interns, residents and fellows, who were asked to fill in a structured, self-designed questionnaire. Most of the responses required a rating on a scale of 1-5 (1 being highly unsatisfactory …


Diagnostic Utility Of Cerebral White Matter Integrity In Early Alzheimer's Disease, David K. Johnson, Willis Barrow, RaeAnn E. Anderson, Amith Harsha, Robyn Honea, William M. Brooks, Jeffrey M. Burns 2010 University of North Dakota

Diagnostic Utility Of Cerebral White Matter Integrity In Early Alzheimer's Disease, David K. Johnson, Willis Barrow, Raeann E. Anderson, Amith Harsha, Robyn Honea, William M. Brooks, Jeffrey M. Burns

Psychology Faculty Publications

We compared white matter integrity with brain atrophy in healthy controls and participants with very mild dementia (Clinical Dementia Rating 0 vs. 0.5) from the Brain Aging Project, a longitudinal study of aging and memory at the University of Kansas Medical Center. Structural magnetic resonance imaging and diffusion tensor imaging (DTI) including fractional anisotropy and mean diffusivity were performed on 27 patients with very mild dementia (Clinical Dementia Rating = 0.5) of the Alzheimer's type (DAT), and 32 cognitively normal subjects. Patient groups were compared across 6 volumetric measures and 14 DTI regions of interest. Very mildly demented patients showed …


William B. Lewis, Second Auditor’S Office, Treasury Department [Washington, Dc] To W. Beaumont [Saint Louis, Mo] Regarding: Returns Of Hospital And Medical Stores Of September 30, 1837 Received. February 20, 1839, 2010 Washington University School of Medicine

William B. Lewis, Second Auditor’S Office, Treasury Department [Washington, Dc] To W. Beaumont [Saint Louis, Mo] Regarding: Returns Of Hospital And Medical Stores Of September 30, 1837 Received. February 20, 1839

1839

No abstract provided.


Letter From W. B. (William B.) Lewis, Second Auditor’S Office, Treasury Department, Washington, Dc, To W. Beaumont, Saint Louis, Mo, Regarding: Returns Of Hospital And Medical Stores Of September 30, 1837 Received. February 20, 1839, 2010 Washington University School of Medicine

Letter From W. B. (William B.) Lewis, Second Auditor’S Office, Treasury Department, Washington, Dc, To W. Beaumont, Saint Louis, Mo, Regarding: Returns Of Hospital And Medical Stores Of September 30, 1837 Received. February 20, 1839

1839

No abstract provided.


Overview Of The Essential Tremor, Theresa A. Zesiewicz, Abinaya Chari, Israt Jahan, Amber M. Miller, Kelly L. Sullivan 2010 University of South Florida

Overview Of The Essential Tremor, Theresa A. Zesiewicz, Abinaya Chari, Israt Jahan, Amber M. Miller, Kelly L. Sullivan

Kelly L. Sullivan

Essential tremor (ET) is one of the most common movement disorders in the world. Despite this, only one medication (propranolol) is approved by the Food and Drug Administration (FDA) to treat it. Fortunately, recent studies have identified some additional medications as treatment of ET. Surgical procedures, such as deep brain stimulation of the ventral intermediate nucleus of the thalamus, offer treatment for refractory tremor. The epidemiology, pathogenesis, and medical and surgical treatment of ET will be discussed in this paper.


Variability Of Syntactic Complexity In Persons With And Without Multiple Sclerosis, Kristin Diane Bjorkman 2010 Brigham Young University - Provo

Variability Of Syntactic Complexity In Persons With And Without Multiple Sclerosis, Kristin Diane Bjorkman

Theses and Dissertations

Several recent studies have suggested that persons with multiple sclerosis (MS) have diminished syntactic complexity. A greater variability in responses to a variety of tasks has also been noted for persons with MS. However, naturalistic data on syntactic complexity and the complexity's variability in persons with MS have not been examined. In the present study, 8 volunteers with MS (age 18-70 years) and 10 adults without MS participated in both a 15-minute conversational language sample and a sentence completion task in two different sessions. No significant differences were found between groups on any measure, and variability within the groups was …


A Pilot Study To Determine The Effectiveness Of Probiotic Use In Elderly Patients With Antibiotic-Associated Diarrhea, Jenna L. Peate 2010 University of Nebraska at Lincoln

A Pilot Study To Determine The Effectiveness Of Probiotic Use In Elderly Patients With Antibiotic-Associated Diarrhea, Jenna L. Peate

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Long-term care settings have the majority of their patients on multiple antibiotics, and outbreaks of antibiotic-associated diarrhea and Clostridium difficile are common. Probiotics have been used with these patients to reduce these side effects. Probiotics can re-establish the composition of intestinal microflora, enhance immune response, and clear pathogens from the host which may reduce the symptoms of antibiotic-associated diarrhea. Therefore, the goal of this study was to conduct a retrospective study of the effectiveness of using probiotic in elderly patients in a long-term care facility in a Midwestern city who suffered from antibiotic-associated diarrhea. The probiotic, CulturelleTM had been administered …


Models Of Disease, Chris Del Mar, Jenny Doust, Paul Glasziou 2010 Bond University

Models Of Disease, Chris Del Mar, Jenny Doust, Paul Glasziou

Paul Glasziou

[Excerpt] What we will do here is set out some models of disease, and then apply them to some clinical problems to see how the models shape up. The models of disease we discuss are not all mutually exclusive, but different ways of viewing the clinical problems we encounter. The models include: *Cause and effect models, and their several variants; *‘edge of the distribution’ illnesses (also known as ‘spectrum disorders’); *Spontaneously remitting and self-perpetuating illnesses; and *‘alternative’ medicine models. These are all ‘transparent box’ approaches to disease: that is, a model of how the disease works, which in turn should …


Teaching Evidence Based Medicine Should Be Integrated Into Current Clinical Scenarios, Chris Del Mar, Paul Glasziou, Dan Mayer 2010 Bond University

Teaching Evidence Based Medicine Should Be Integrated Into Current Clinical Scenarios, Chris Del Mar, Paul Glasziou, Dan Mayer

Paul Glasziou

The editorial discusses some elements of teaching and learning evidence based medicine. It comments on the variable level of education that students receive in EBM. Many of our future clinicians will be users of research rather than producers of it and unless students see their role models use EBM in clinical practice they are unlikely to value it as clinically important. Students have to grasp two essential principles of EBM: its empirical approach to optimal clinical decisions and its quantitative expression. This requires some mastery of epidemiology and statistics as well as adequate access to electronic information at the point …


Antibiotics For Acute Otitis Media In Children [Review], Paul P. Glasziou, Chris Del Mar, Sharon L. Sanders, Mauricio Hayem 2010 Bond University

Antibiotics For Acute Otitis Media In Children [Review], Paul P. Glasziou, Chris Del Mar, Sharon L. Sanders, Mauricio Hayem

Paul Glasziou

Background: Acute otitis media is one of the most common diseases in early infancy and childhood. Antibiotic use for acute otitis media varies from 31% in the Netherlands to 98% in the USA and Australia. Objectives: The objective of this review was to assess the effects of antibiotics for children with acute otitis media. Search strategy: We searched the Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE, Index Medicus (pre 1965), Current Contents and reference lists of articles from 1958 to January 2000. The search was updated in 2003. Selection criteria: Randomised trials comparing antimicrobial drugs with placebo in children …


Sore Throat, Chris Del Mar, Paul Glasziou 2010 Bond University

Sore Throat, Chris Del Mar, Paul Glasziou

Paul Glasziou

Abstract: This article considers the effects of interventions to reduce symptoms and complications of acute infective sore throat. It defines the condition and looks in detail at the areas of treatment, incidence, risk factors, methods and prognosis.


The State Of Primary-Care Research, David Mant, Chris Del Mar, Paul Glasziou, Andre Knottnerus, Paul Wallace, Chris Van Weel 2010 Bond University

The State Of Primary-Care Research, David Mant, Chris Del Mar, Paul Glasziou, Andre Knottnerus, Paul Wallace, Chris Van Weel

Paul Glasziou

In March, 2003, the editor of The Lancet attended an international conference in Kingston, Ontario, Canada, on primary-care research, subsequently running a rather dyspeptic editorial entitled "Is primary-care research a lost cause?" (1) This article highlighted the unacceptable weakness of primary-care research worldwide. A particular concern of the conference was the shortage of primary care research in less economically developed countries to inform the clinical and public health management of malnutrition, malaria, AIDS, water-borne infection, and other illnesses of poverty (2). However, problems exist even in economically developed countries. In Australia, for example, a crude measure of research productivity with …


Tapping The Potential Of The Health Care Workforce: Scope-Of-Practice And Payment Policies For Advanced Practice Nurses And Physician Assistants, Robert Cunningham 2010 Himmelfarb Health Sciences Library, The George Washington University

Tapping The Potential Of The Health Care Workforce: Scope-Of-Practice And Payment Policies For Advanced Practice Nurses And Physician Assistants, Robert Cunningham

National Health Policy Forum

Expanding coverage and increasing delivery of team-based care are likely to entail a growing role in the
health system for advanced practice nurses (APNs), physician assistants (PAs), and other nonphysician clinicians. These professions have already grown rapidly and have increased access to primary and specialty care, especially in rural and other underserved areas. This background paper provides an overview of the role of APNs and PAs. It reviews the primary features of the training and credentialing of these health professions, including the impact of public policies and market forces on their growth and deployment. It describes variations in state scope-of-practice …


The Development Of Attribute Dominance In The Knowledge Base, Marc A. Lindberg Ph.D. 2010 Marshall University

The Development Of Attribute Dominance In The Knowledge Base, Marc A. Lindberg Ph.D.

Psychology Faculty Research

Two cuing, free-recall studies were conducted to test Bach and Underwood's (1970) hypothesis that acoustic encoding is dominant among second graders and semantic encoding is dominant among sixth graders. When retrieval cues were presented with to-be-remembered items at both input and output (Experiment 1), and when cues were presented only at output (Experiment 2), semantic cues were more efficient in elevating recall than were acoustic cues for both second and sixth graders. When these and other results generally found using recognition, sorting, incidental learning, and free-recall experimental designs are compared, it seems plausible that item presentation and memory-testing formats interact …


Avirulent Uracil Auxotrophs Based On Disruption Of Orotidine-5′-Monophosphate Decarboxylase Elicit Protective Immunity To Toxoplasma Gondii, Barbara A. Fox, David J. Bzik 2010 Dartmouth College

Avirulent Uracil Auxotrophs Based On Disruption Of Orotidine-5′-Monophosphate Decarboxylase Elicit Protective Immunity To Toxoplasma Gondii, Barbara A. Fox, David J. Bzik

Dartmouth Scholarship

The orotidine-5'-monophosphate decarboxylase (OMPDC) gene, encoding the final enzyme of the de novo pyrimidine biosynthesis pathway, was deleted using Toxoplasma gondii KU80 knockouts to develop an avirulent nonreverting pyrimidine auxotroph strain. Additionally, to functionally address the role of the pyrimidine salvage pathway, the uridine phosphorylase (UP) salvage activity was knocked out and a double knockout of UP and OMPDC was also constructed. The nonreverting DeltaOMPDC, DeltaUP, and DeltaOMPDC DeltaUP knockout strains were evaluated for pyrimidine auxotrophy, for attenuation of virulence, and for their ability to elicit potent immunity to reinfection. The DeltaUP knockout strain was replication competent and virulent. In …


Pcif1 Modulates Pdx1 Protein Stability And Pancreatic Β Cell Function And Survival In Mice, Kathryn C. Claiborn, Mira M. Sachdeva, Corey E. Cannon, David N. Groff, Jeffrey D. Singer, Doris A. Stoffers 2010 University of Pennsylvania School of Medicine

Pcif1 Modulates Pdx1 Protein Stability And Pancreatic Β Cell Function And Survival In Mice, Kathryn C. Claiborn, Mira M. Sachdeva, Corey E. Cannon, David N. Groff, Jeffrey D. Singer, Doris A. Stoffers

Biology Faculty Publications and Presentations

The homeodomain transcription factor pancreatic duodenal homeobox 1 (Pdx1) is a major mediator of insulin transcription and a key regulator of the β cell phenotype. Heterozygous mutations in PDX1 are associated with the development of diabetes in humans. Understanding how Pdx1 expression levels are controlled is therefore of intense interest in the study and treatment of diabetes. Pdx1 C terminus–interacting factor-1 (Pcif1, also known as SPOP) is a nuclear protein that inhibits Pdx1 transactivation. Here, we show that Pcif1 targets Pdx1 for ubiquitination and proteasomal degradation. Silencing of Pcif1 increased Pdx1 protein levels in cultured mouse β cells, and Pcif1 …


Development Of Psychometrically Equivalent Speech Recognition Threshold Materials For Native Speakers Of Samoan, Jennifer Lane Newman 2010 Brigham Young University - Provo

Development Of Psychometrically Equivalent Speech Recognition Threshold Materials For Native Speakers Of Samoan, Jennifer Lane Newman

Theses and Dissertations

The speech recognition threshold (SRT) is an important measure, as it validates the pure-tone average (PTA), assists in the diagnosis and prognosis of hearing impairments, and aids in the identification of non-organic hearing impairments. Research has shown that in order for SRT testing to yield valid and reliable measures, testing needs to be performed in the patient's native language. There are currently no published materials for SRT testing in the Samoan language. As a result, audiologists are testing patients with English materials or other materials not of the patient's native language. Results produced from this manner of testing are confounded …


Medical School Watercooler Newsletter - July 4, 2010, Lindsey Lyle 2010 University of South Alabama

Medical School Watercooler Newsletter - July 4, 2010, Lindsey Lyle

Watercooler Newsletter

This is the July 4, 2010 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

  • Outpatient ENT Practice Added On Campus
  • S.T.A.R.S. Program Provides Enrichment Coursework, Health Care Internships for High School Seniors
  • Dr. Naritoku Appointed to Serve on Board of American Board of Clinical Pharmacology
  • USA Medical Student Returns From Doris Duke Clinical Research Fellowship
  • USA College of Medicine Scientist Appointed To Cancer Etiology Study Section


Accuracy Of English Speakers Administering Word Recognition Score Tests In Mandarin, Kaylene Barrett Polley 2010 Brigham Young University - Provo

Accuracy Of English Speakers Administering Word Recognition Score Tests In Mandarin, Kaylene Barrett Polley

Theses and Dissertations

The purpose of this study was to examine the accuracy of English-speakers in determining the word recognition score of native Taiwan Mandarin-speakers. Digitally recorded Mandarin word lists were presented to 10 native Mandarin-speakers from Taiwan (five male, five female), from whom oral and written responses were collected. Oral responses were scored by 30 native English-speakers, 15 of which had no experience with Mandarin and 15 with two to three years of college-level Mandarin courses or equivalent knowledge of Mandarin. The judges who had experience with Mandarin were able to score the WRS tests with 97% accuracy (with scores ranging from …


Antispasmodic, Bronchodilator And Blood Pressure Lowering Properties Of Hypericum Oblongifolium - Possible Mechanism Of Action, Arif-ullah Khan, Munasib Khan, Fazal Subhan, Anwar Gilani 2010 Aga Khan University

Antispasmodic, Bronchodilator And Blood Pressure Lowering Properties Of Hypericum Oblongifolium - Possible Mechanism Of Action, Arif-Ullah Khan, Munasib Khan, Fazal Subhan, Anwar Gilani

Department of Biological & Biomedical Sciences

The crude extract of Hypericum oblongifolium (Ho.Cr), which tested positive for flavonoids, saponins and tannins caused concentration-dependent (0.1-1.0 mg/mL) relaxation of spontaneous and high K(+) (80 mM)-induced contractions in isolated rabbit jejunum preparations, suggesting a Ca(++) antagonistic effect, which was confirmed when pretreatment of the tissue with Ho.Cr produced a rightward shift in the Ca(++) concentration-response curves, like that caused by verapamil. Ho.Cr relaxed carbachol (1 mu M) and high K(+)-induced contractions in guinea pig tracheal preparations. It caused a dose-dependent (3-100 mg/kg) fall in arterial blood pressure of rats under anesthesia. In isolated guinea pig atria, Ho.Cr caused inhibition …


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