Other Medicine and Health Sciences Commons^™

Fumarate-Based Polymers: Oligo(Poly(Ethylene Glycol) Fumarate) And Poly(Butylene Fumarate) For Tissue Engineering Heart Valve And Bone Tissue, Christian T. Denny

Biomedical Engineering ETDs

Tissue engineering is an emerging field that came from the fields of medicine, materials science, and engineering. The foundation of tissue engineering uses a paradigm that incorporates cells, biomaterials, and exogenous factors to create living tissues for medical, pharmaceutical, and research purposes. Within the last 100 years, biomaterials have been developed to solve many medical and research problems. As biomaterials have developed throughout the years new materials have been developed to have specific properties appropriate for medical applications. Fumarate is a naturally derived molecule in the body and has been found useful for developing polyesters that can be crosslinked into …

Direct Entry Midwives: Political Factors Shaping Variation In Regulation, Gabrielle Shlikas

The Compass

No abstract provided.

Alumni Journal - Volume 93, Number 1, Loma Linda University, School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | From the Editor
4 | From the President
6 | From the Dean

News
7 | This and That
12 | Alumni News
13 | Students
14 | School of Medicine News
16 | AIMS Report
18 | Department Reports: Psychiatry and Neurosurgery

APC 2022
22 | APC 2022 in Review

Features
35 | Alumni Spotlight
36 | Whole Person Care Today
39 | Arthur N. Donaldson, Class of 1915
42 | The Call

In Memoriam
44 | Featured Obituary: Brian S. Bull '61
45 | Alumni Remembered

A Push For Inclusive Data Collection In Stem Organizations, Nicholas P. Burnett, Alyssa M. Hernandez, Emily E. King, Richelle L. Tanner, Kathryn Wilsterman

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Professional organizations in STEM (science, technology, engineering, and mathematics) can use demographic data to quantify recruitment and retention (R&R) of underrepresented groups within their memberships. However, variation in the types of demographic data collected can influence the targeting and perceived impacts of R&R efforts - e.g., giving false signals of R&R for some groups. We obtained demographic surveys from 73 U.S.-affiliated STEM organizations, collectively representing 712,000 members and conference-attendees. We found large differences in the demographic categories surveyed (e.g., disability status, sexual orientation) and the available response options. These discrepancies indicate a lack of consensus regarding the demographic groups that …

The Prevalence Of Red-S Among College Athletes, Johnny Nguyen

Graduate Research Posters

Relative Energy Deficiency in Sports (RED-S) is a phenomenon established by the International Olympic Committee to expand on the previously known condition as the female athlete triad, to include male athletes. Relative Energy Deficiency in Sports is a physiological functioning impairment due to athletes with low energy availability. Low energy occurs when athletes expend more energy (calorie burn with activity) than they consume (daily caloric intake) for an extended period. Leading to alter or impaired physiological function. College is a period where individuals gain their independence. Collegiate student-athletes are learning to juggle multiple aspects of their life. Along with excelling …

Applications Of Unsupervised Machine Learning In Autism Spectrum Disorder Research: A Review, Chelsea Parlett-Pelleriti, Elizabeth Stevens, Dennis R. Dixon, Erik J. Linstead

Engineering Faculty Articles and Research

Large amounts of autism spectrum disorder (ASD) data is created through hospitals, therapy centers, and mobile applications; however, much of this rich data does not have pre-existing classes or labels. Large amounts of data—both genetic and behavioral—that are collected as part of scientific studies or a part of treatment can provide a deeper, more nuanced insight into both diagnosis and treatment of ASD. This paper reviews 43 papers using unsupervised machine learning in ASD, including k-means clustering, hierarchical clustering, model-based clustering, and self-organizing maps. The aim of this review is to provide a survey of the current uses of …

Senior Academic Ranks In Us Anesthesiology Programs: Differences Between Women And Men And Examination Of Independent Factors For Success, Brenda Lee, Farhad Zahedi, Ina Zaimi, Roman Schumann

Journal of Maine Medical Center

Introduction: Gender equality among faculty is a challenge in academic medicine, including anesthesiology. We investigated the likelihood that several factors were associated with academic success in the United States (US), defined as having achieved a senior academic rank (SAR) in a US anesthesiology training program.

Methods: We collected data available on the Internet on 131 anesthesiology programs, including faculty academic rank, gender, number of faculty, graduate status from an American medical school, fellowship training status, number of residents, number of program fellowships, and geographic location. SAR was defined as either associate professor or professor. Data were analyzed with logistic regression. …

A Vision Fulfilled, Loma Linda University Health

Scope

Table of Contents

Features
6 | A campus transformation
16 | New Children's Hospital tower
20 | Virtual reality
24 | Golden years restored
26 | Global service
36 | WARNING! Snakes on page 36!

Departments
4 | From the President: A vision fulfilled
28 | News: Clinical and campus news
40 | Alumni: Serving our world
44 | Annual Report: The fiscal year's people and status

Simple Method For Cutoff Point Identification In Descriptive High-Throughput Biological Studies, Alexander Suvorov

Environmental Health Sciences Faculty Publication Series

Background

Rapid development of high-throughput omics technologies generates an increasing interest in algorithms for cutoff point identification. Existing cutoff methods and tools identify cutoff points based on an association of continuous variables with another variable, such as phenotype, disease state, or treatment group. These approaches are not applicable for descriptive studies in which continuous variables are reported without known association with any biologically meaningful variables.

Results

The most common shape of the ranked distribution of continuous variables in high-throughput descriptive studies corresponds to a biphasic curve, where the first phase includes a big number of variables with values slowly growing …

Health Sciences First Year Seminar Library Lesson Plan (Hsf90), Ian Mcdermott

Open Educational Resources

This lesson plan, and accompanying slides, is for the library instruction session for HSF90, LaGuardia Community College's health sciences first year seminar course. The lesson details the importance of college-level research for students who will enter various health sciences professions. The lesson also covers the importance of citation in academic research, covering what to cite and how to do it using library subscription databases.

Investigating The Uncertainties In Ct Non-Small Cell Lung Cancer Radiomics, Gary Ge

Theses and Dissertations--Radiation Medicine

Radiomics is a technique that extracts quantitative features, termed radiomic features, from medical images using data-characterization algorithms. These radiomic features can be used to identify tissue characteristics and radiologic phenotyping that are not observable by clinicians in a non-invasive, low-cost manner, potentially generating image biomarkers for clinical decision. To date, there are still many uncertainties involved in radiomics which limit its clinical implementation. Herein, we propose to explore the impact of each component in the radiomics pipeline on predicting clinical outcomes. In Chapter II, we conduct a thorough review of CT lung cancer radiomics studies to examine the typical feature …

Examining The Effects Of Exercise-Induced, Physical Stress Overtraining On Stress Biomarkers In Adolescent, C57bl/6 Mice, Curtis Scotty Davis

Theses, Dissertations and Capstones

Exercise has long been established as a therapeutic modality to improve health and related physical fitness, sports performance, and injury/risk reduction in both adults and adolescents (Haff & Triplett, 2015; Kaminsky, 2010). Nonetheless, there is a lack of research investigating the negative effects of exercise overstress (i.e., overtraining syndrome) in these populations, particularly adolescents (Brenner & American Academy of Pediatrics Council on Sports Medicine and Fitness, 2007; Matos & Winsley, 2007). The objective of this study was to examine hormone biochemical markers, anthropometric markers, and behavioral traits, which are associated with overtraining syndrome, in adolescent C57BL/6 mice. A total of …

Calidad De Vida Relacionada Con La Visión En Pacientes Con Retinopatía Diabética No Proliferativa Atendidos En Fundación Para El Desarrollo De La Mujer En San Salvador, El Salvador, María Asunción Betancourth Zúniga

Maestría en Ciencias de la Visión

La Retinopatía Diabética (RD) es una enfermedad retiniana, que no sólo afecta el alcance visual, también influye en la sensibilidad al contraste, percepción del color, campo visual, sensibilidad a los cambios de iluminación y por ende en la calidad de vida. En este estudio se evaluó la calidad de vida relacionada con la visión en pacientes con retinopatía diabética no proliferativa atendidos en Fundación para el Desarrollo de la Mujer (FUDEM) en San Salvador, el Salvador. Materiales y Métodos: Este fue un estudio observacional que incluyó 30 pacientes referidos de la unidad de retina con diagnóstico de Retinopatía Diabética No …

Community-Based Ot Program Planning: A Virtual Level Ii Fieldwork Program Developed In Response To The Global Pandemic, Tara Collins, Virginia E. Koenig, Stephanie J. Wong, Michelle Buccinna, Rena B. Purohit, Shifra K. Leiser, Debra Cullinane

Journal of Occupational Therapy Education

The purpose of this article is to explain how an occupational therapy (OT) program in a university setting developed a virtual Level II community-based fieldwork program in response to the COVID-19 global pandemic. This virtual fieldwork program, guided by the PRECEDE-PROCEED Planning Model (PPM), was designed to help keep students on track with their academic goals while providing them with experiential learning that would increase their confidence in OT program planning and promote their professional development. Outcome measures for this study consisted of a pre-and post-fieldwork survey that asked participants to rank their self-perceived confidence in five distinct areas of …

Adoption And Diffusion Of At-Home Medical Tests, Savannah Campbell, Mark Mitchell, Jerome Christia, Melissa Clark

Atlantic Marketing Journal

The purpose of this study is to understand the at-home medical test market including the medical and regulatory requirements to create at-home medical tests, as well as the market factors that influence consumer adoption in the context of the COVID-19 pandemic. To address testing shortages of COVID-19 tests companies created at-home tests which were rapidly approved by the FDA, bringing at-home testing to the forefront.

History of at-home health testing is reviewed, the medical requirements for creating them, and how the pandemic has affected such testing. Tables are also included to demonstrate currently available tests and potential future tests. The …

The Dogma Of Tissue Ischemia With Local Anesthetic And Epinephrine Use, Laura Morrissey

Capstone Showcase

Epinephrine is often combined with Lidocaine for local anesthetic use as it improves the duration and quality of Lidocaine and promotes wound hemostasis.^1-2 Despite these benefits, epinephrine has been historically contraindicated from being injected into fingers, toes, ears and the nose due to concern over the vasoconstrictive properties of epinephrine leading to ischemia in these end-arteriole areas.^3-7 However, there is very little documented evidence of this happening with epinephrine use.^5-13 An exhaustive review done by Denkler in 2001 reviewed 21 cases between 1889-2001 that involve epinephrine local injection prior to digit ischemia. However, none of these cases …

Multi-Modality Automatic Lung Tumor Segmentation Method Using Deep Learning And Radiomics, Siqiu Wang

Theses and Dissertations

Delineation of the tumor volume is the initial and fundamental step in the radiotherapy planning process. The current clinical practice of manual delineation is time-consuming and suffers from observer variability. This work seeks to develop an effective automatic framework to produce clinically usable lung tumor segmentations. First, to facilitate the development and validation of our methodology, an expansive database of planning CTs, diagnostic PETs, and manual tumor segmentations was curated, and an image registration and preprocessing pipeline was established. Then a deep learning neural network was constructed and optimized to utilize dual-modality PET and CT images for lung tumor segmentation. …

Utilizing Virtual Reality Goggles During Pediatric Laceration Repairs To Reduce Perceived Pain In Pediatric Patients, Emily C. Bozzer

MSU Graduate Theses

In pediatric emergency departments, several providers assess pediatric patients in need a laceration repair, require procedural sedation in order to ensure compliance and complete the laceration repair. This study explored one safe alternative to procedural sedation during pediatric laceration repairs by assessing what pain scores pediatric patients report when undergoing a laceration repair utilizing virtual reality goggles. Pediatric patients ages 6-17 years old perceived pain scores utilizing FACES pain scale was documented. This study found a majority of patients reported lower pain scores during the laceration repair in comparison to their baseline pain score.

Genetic And Genomic Architecture In Eight Strains Of The Laboratory Opossum Monodelphis Domestica, Xiao Xiong, Paul B. Samollow, Wenqi Cao, Richard Metz, Chao Zhang, Ana C. Leandro, John L. Vandeberg, Xu Wang

School of Medicine Publications and Presentations

The gray short-tailed opossum (Monodelphis domestica) is an established laboratory-bred marsupial model for biomedical research. It is a critical species for comparative genomics research, providing the pivotal phylogenetic outgroup for studies of derived vs ancestral states of genomic/epigenomic characteristics for eutherian mammal lineages. To characterize the current genetic profile of this laboratory marsupial, we examined 79 individuals from eight established laboratory strains. Double digest restriction site-associated DNA sequencing and whole-genome resequencing experiments were performed to investigate the genetic architecture in these strains. A total of 66,640 highquality single nucleotide polymorphisms (SNPs) were identified. We analyzed SNP density, average heterozygosity, nucleotide …

The Effects Of Caffeine On Health And Perceived Bitterness, Chyann Farlin

Williams Honors College, Honors Research Projects

Caffeine is commonly consumed throughout the world in items such as coffee, chocolate, tea, energy drinks, and carbonated soft drinks. Consumers and food manufacturers benefit from discussion surrounding caffeine because consumers use information to drive their purchases. The purpose of this paper is to describe how caffeine effects health and perceived bitterness, and the ways that the food industry modifies bitter tastes in caffeine-containing products. Moderate caffeine intake is defined as 240-400 mg/day. Moderate intake of caffeine is not correlated to increased risk of premature death caused by disease or cancer. Excessive intake (>400mg/day) is neither protective nor harmful …