Phaeophleospora Vochysiae Savi & Glienke Sp. Nov. Isolated From Vochysia Divergens Found In The Pantanal, Brazil, Produces Bioactive Secondary Metabolites, Daiani C. Savi, Khaled A. Shaaban, Francielly M. W. Gos, Larissa V. Ponomareva, Jon S. Thorson, Chirlei Glienke, Jürgen Rohr
Pharmaceutical Sciences Faculty Publications
Microorganisms associated with plants are highly diverse and can produce a large number of secondary metabolites, with antimicrobial, anti-parasitic and cytotoxic activities. We are particularly interested in exploring endophytes from medicinal plants found in the Pantanal, a unique and widely unexplored wetland in Brazil. In a bio-prospecting study, strains LGMF1213 and LGMF1215 were isolated as endophytes from Vochysia divergens, and by morphological and molecular phylogenetic analyses were characterized as Phaeophleospora vochysiae sp. nov. The chemical assessment of this species reveals three major compounds with high biological activity, cercoscosporin (1), isocercosporin (2) and the new compound 3-(sec-butyl)-6-ethyl-4,5-dihydroxy-2-methoxy-6-methylcyclohex-2-enone ...
Discovery Of Bioactive Natural Products From Sugarcane, 2018 Southern Cross University
Discovery Of Bioactive Natural Products From Sugarcane, Rory Patrick Taylor
This research was undertaken to discover new potential products (with a focus on flavonoids) from sugarcane and sugar production by-products that have pharmaceutical, nutraceutical or functional food applications. Specifically, cytotoxic, antioxidant, anti-inflammatory/immune modulation and glycaemic index (GI) activities were surveyed. The results suggest that there are potentially novel anti-inflammatory and α-amylase inhibiting compound(s) present. These extracts or compounds may have use in the treatment of diabetes mellitus type 2 or inflammation-related diseases such as arthritis, multiple sclerosis and atherosclerosis. Further research such as compound identification and in vivo testing is warranted.
The Role Of Co-Opted Escrt Proteins And Lipid Factors In Protection Of Tombusviral Double-Stranded Rna Replication Intermediate Against Reconstituted Rnai In Yeast, Nikolay Kovalev, Jun-Ichi Inaba, Zhenghe Li, Peter D. Nagy
Plant Pathology Faculty Publications
Reconstituted antiviral defense pathway in surrogate host yeast is used as an intracellular probe to further our understanding of virus-host interactions and the role of co-opted host factors in formation of membrane-bound viral replicase complexes in protection of the viral RNA against ribonucleases. The inhibitory effect of the RNA interference (RNAi) machinery of S. castellii, which only consists of the two-component DCR1 and AGO1 genes, was measured against tomato bushy stunt virus (TBSV) in wild type and mutant yeasts. We show that deletion of the co-opted ESCRT-I (endosomal sorting complexes required for transport I) or ESCRT-III factors makes TBSV replication ...
Photosynthetic Bacterium Rhodopseudomonas Palustris Gj-22 Induces Systemic Resistance Against Viruses, 2017 Hunan Academy of Agricultural Sciences, China
Photosynthetic Bacterium Rhodopseudomonas Palustris Gj-22 Induces Systemic Resistance Against Viruses, Pin Su, Xinqiu Tan, Chenggang Li, Deyong Zhang, Ju’E Cheng, Songbai Zhang, Xuguo Zhou, Qingpin Yan, Jing Peng, Zhuo Zhang, Yong Liu, Xiangyang Lu
Entomology Faculty Publications
Photosynthetic bacteria (PSB) have been extensively used in agriculture to promote plant growth and to improve crop quality. Their potential application in plant disease management, however, is largely overlooked. In this study, the PSB strain Rhodopseudomonas palustris GJ-22 was investigated for its ability to induce resistance against a plant virus while promoting plant growth. In the field, a foliar spray of GJ-22 suspension protected tobacco plants against tobacco mosaic virus (TMV). Under axenic conditions, GJ-22 colonized the plant phyllosphere and induced resistance against TMV. Additionally, GJ-22 produced two phytohormones, indole-3-acetic acid and 5-aminolevulinic acid, which promote growth and germination in ...
Glucose-Mediated Catabolite Repression In Sinorhizobium Meliloti, 2017 University of Redlands
Glucose-Mediated Catabolite Repression In Sinorhizobium Meliloti, Emily R. Murnin
Undergraduate Honors Theses
Alfalfa plants and the bacteria Sinorhizobium meliloti interact in a symbiotic relationship in which the alfalfa plant receives a usable form of nitrogen, ammonia, to use as a fertilizer, while the bacteria receive a carbon and energy source from the plant roots. During this exchange, there is formation of a root nodule, and these bacteria are implanted inside the alfalfa root cells. To convert the nitrogen by the process of nitrogen fixation for the alfalfa plant, Sinorhizobium meliloti requires a great deal of energy. To conserve the energy that it has, this bacterium performs what is known as catabolite ...
Surviving Catastrophe: Resource Allocation And Plant Interactions Among The Mosses Of Mount St. Helens Volcano, 2016 Portland State University
Surviving Catastrophe: Resource Allocation And Plant Interactions Among The Mosses Of Mount St. Helens Volcano, Trevor David Williams
Dissertations and Theses
Mosses are some of the first colonizers to disturbed sites, yet their roles in early plant community structuring are not well understood. The primary succession zones of volcanoes provide opportunities to conduct natural experiments into how mosses contribute to early plant community formation, as well as how the unique environments found in such zones affect plant traits, particularly those associated with stress tolerance. Though plant community changes have been well-documented since Mount St. Helens (MSH) volcano erupted in 1980, the volcano's moss assemblages, their influence on other plants, and their potential roles in chemical-mediated competition and biogeochemical cycling have ...
Organics: Exploring The Parallels Between Botany And Human Anatomy Through Sculpture And Watercolor Painting, 2016 Union College - Schenectady, NY
Organics: Exploring The Parallels Between Botany And Human Anatomy Through Sculpture And Watercolor Painting, Allison Borek
Integrating my two passions of the visual arts and science for my senior thesis, I created a collection of paintings that represent human organs and the parallels between plant biology and animal biology. Genetically, plants are just as complex – if not more – than many animals. They have intricate sensory and regulatory systems highly comparable to humans, and on a cellular level, we share many analogous features. In addition, every single carbon atom that makes up the human body was at one time fixed in a plant during photosynthesis. We also rely on photosynthesis to give us the oxygen we breathe ...
13c Composition In Bryophyte Primary Sugars As An Indicator Of Water Availability, 2016 Union College - Schenectady, NY
13c Composition In Bryophyte Primary Sugars As An Indicator Of Water Availability, Olivia Hope Williamson
Bryophytes (mosses and their relatives) are a major carbon sink, and their productivity, is expected to be affected by climate change. Changes in plant productivity caused by changes in the climate can be tracked through stable carbon isotopes. This research aims to find a connection between stable carbon isotope signatures and water availability in bryophytes by examining the composition of 13C in soluble sugars and bulk tissue. Similar to trees, which leave rings of growth every year, mosses build up peat deposits, which can be used to gain information about the weather and water availability of a region. Information on ...
A Preliminary Study On The Role Of Enhancer Of Flavonoid Production (Efp) In Flavonoid Biosynthesis, 2016 University of Connecticut
A Preliminary Study On The Role Of Enhancer Of Flavonoid Production (Efp) In Flavonoid Biosynthesis, Jia Guo
Honors Scholar Theses
Flavonoids are involved in a variety of biological roles ranging from pathogen protection, pigment intensity, antioxidant effects, and even prevention from cancer or cardiovascular diseases. Because of the diverse and beneficial functions that flavonoids have, the flavonoid biosynthetic pathway has been well studied. Recently, a gene called the Enhancer of Flavonoid Production (EFP) was discovered when mutations in this gene caused the Japanese morning glory flowers to exhibit a pale-colored phenotype. Although EFP is known to increase flavonoid production, the direct mechanism to how EFP enhances enzymes in the flavonoid biosynthetic pathway has yet to be discovered. It has been ...
Mechanisms Of Adaptation In The Newly Invasive Species Brachypodium Sylvaticum (Hudson) Beauv., 2015 Portland State University
Mechanisms Of Adaptation In The Newly Invasive Species Brachypodium Sylvaticum (Hudson) Beauv., Gina Lola Marchini
Dissertations and Theses
It is common knowledge that invasive species cause worldwide ecological and economic damage, and are nearly impossible to eradicate. However, upon introduction to a novel environment, alien species should be the underdogs: They are present in small numbers, possess low genetic diversity, and have not adapted to the climate and competitors present in the new habitat. So, how are alien species able to invade an environment occupied by native species that have already adapted to the local environment? To discover some answers to this apparent paradox I conducted four ecological genetic studies that utilized the invasive species Brachypodium sylvaticum (Hudson ...
Anti-Tb And Antibacterial Activities Of Natural Products Extracts, 2015 Olivet Nazarene University
Anti-Tb And Antibacterial Activities Of Natural Products Extracts, Douglas Armstrong, Nathan Krause, Drew Frey
Faculty Scholarship – Chemistry
Samples of numerous plant species were received from the southwestern part of the USA from Richard Spjut, and plant samples were collected here in Illinois. All were extracted with typical solvents, giving crude residues, some of which were subjected to counter-current or flash chromatographic methods. Some of the crude extracts and chromatographic fractions had anti-tuberculosis and/or antibacterial activity.
In a general way, bioactive natural products are dealt with very well by Liang & Fang, 2006. More specifically, the southwestern part of the United States has a large variety of indigenous plants, many of which have not been investigated for their ...
The Presence And Functionality Of Ammonia Oxidizing Bacteria In The Constructed Treatment Wetland At The John Heinz National Wildlife Refuge, Keith Lewy
Master of Environmental Studies Capstone Projects
The vast majority of research done on constructed treatment wetlands (CTWs) has focused on outdoor installations, with little work done on indoor systems. Previous work on the indoor CTW at the John Heinz National Wildlife Refuge focused on whether the lack of floral diversity in the system would negatively impact its ability to remove various chemical parameters, but despite their great importance in bioremediation the microbial communities in these CTWs have never been studied. In this study, the presence and functionality of ammonia oxidizing bacteria was examined in various points of the treatment system using both culture-dependent and culture-independent DNA-based ...
The Effect Of Pomegranate Juice Extract On The Hedgehog Signaling Pathway In Pancreatic Cancer, 2014 Chapman University
The Effect Of Pomegranate Juice Extract On The Hedgehog Signaling Pathway In Pancreatic Cancer, Veronica Gomez, Talia Shackelford, Autumn Tocchi, Melissa Rowland-Goldsmith
e-Research: A Journal of Undergraduate Work
Pancreatic cancer is the fourth leading cause of cancer death in the United States. There have been several reports indicating that phytochemicals in fruits can reduce the risk of cancer due to the anti-oxidant and anti-inflammatory effects of the polyphenols. Our lab has shown that pomegranate juice extract (PJE) has anti-proliferative and pro-apoptotic effects in human pancreatic cancer cells. In the past, we have shown that cells adhere more strongly to the plate when treated with PJE. This observation prompted an investigation of how PJE regulates cell adhesion proteins. Previously, our lab investigated E-cadherin, a cell adhesion protein. Upon activation ...
Community Level Impacts Associated With The Invasion Of English Ivy (Hedera Spp.) In Forest Park: A Look At The Impacts Of Ivy On Community Composition And Soil Moisture, 2014 Portland State University
Community Level Impacts Associated With The Invasion Of English Ivy (Hedera Spp.) In Forest Park: A Look At The Impacts Of Ivy On Community Composition And Soil Moisture, Sara Rose Copp
Dissertations and Theses
Invasive species degrade ecosystems by altering natural processes and decreasing the abundance and diversity of native flora. Communities with major fluctuations in resource supply allow invasive species to exploit limiting resources making the community prone to invasion. In the Pacific Northwest, urban forests characterized with limited light and seasonally limited soil moisture are being dominated by nonnative English ivy (Hedera spp). Three observational studies were conducted in the Southern end of Forest Park within the Balch Creek Subwatershed in Portland, Oregon in order to understand 1) how English ivy changes over three growing seasons, 2) how the native understory composition ...
The Effects That Liquid And Solid Cattle Manure Have On The Water Quality Of Drainage Ditches In Putnam County, Ohio, 2014 Bowling Green State University
The Effects That Liquid And Solid Cattle Manure Have On The Water Quality Of Drainage Ditches In Putnam County, Ohio, Janelle Horstman
Lake Erie has experienced harmful algal blooms with increased frequency since the mid-1990s due to excess nutrients from Rivers, such as the Maumee River, and largely agricultural watersheds. Nonpoint source pollution from agriculture contributes to eutrophication, algal blooms, and the degradation of water quality. This creates stress on aquatic fauna, reduced aesthetic quality, odor, and limits of the water for usage of drinking, recreation, and industry. This research paper asks what the contributions of having access to manure application records, soil records, and information about antibiotics have on what is known about manure management and antibiotic resistance, which has been ...
Studies On Tracheorelaxant And Anti-Inflammatory Activities Of Rhizomes Of Polygonatum Verticillatum, 2013 Aga Khan University
Studies On Tracheorelaxant And Anti-Inflammatory Activities Of Rhizomes Of Polygonatum Verticillatum, Haroon Khan, Muhammad Saeed, Hassan Mehmood, Najeeb-Ur Rehman, Naveed Muhammad, Ikram-Ul Haq, Nadeem Ashraf, Kamal Eldin H El-Tahir, Anwar Gilani
Department of Biological & Biomedical Sciences
Background: The present study describes the tracheorelaxant and anti-inflammatory effects of Polygonatum verticillatum which may support its medicinal use in hyperactive airway complaints and inflammatory disorders.
Methods: The tracheorelaxant activity of crude extract of the rhizomes of P. verticillatum (PR) was assessed in isolated guinea-pig tracheal tissues immersed in tissue organ bath filled with Tyrode's solution and a continuous supply of carbogen gas (95% O2 and 5% CO2). The contractile and relaxant responses of the tissue were measured using isometric transducers coupled with Power-Lab data acquisition system. The anti-inflammatory effect was evaluated in carrageenan-induced rat paw edema model, while ...
Phytochemistry And Pharmacology Of Plants From The Ginger Family, Zingiberaceae, 2013 Southern Cross University
Phytochemistry And Pharmacology Of Plants From The Ginger Family, Zingiberaceae, Hans Wohlmuth
Dr Hans Wohlmuth
This thesis reports on a series of investigations into the phytochemistry and pharmacology of plants belonging to the ginger family, Zingiberaceae (incl. Costaceae). The work falls into two main parts. The first part examines the pungent compounds and essential oil in 17 clones of ginger (Zingiber officinale) with a view to identify one or more with unique chemistry and consequent particular therapeutic (or flavouring) prospects. The second part comprises the screening of 41 taxa for inhibition of PGE2 and other biological activities, with the primary aim of identifying species with potential anti-inflammatory activity. This part tested the hypothesis that the ...
A Literature Review Of The Health Effects Of A Plant Based Diet Versus An Animal Based Diet, 2013 Liberty University
A Literature Review Of The Health Effects Of A Plant Based Diet Versus An Animal Based Diet, James Cote
Senior Honors Theses
Health and nutrition can mean a myriad of things to many people in today’s culture. The majority of the time people are unaware of the proper nutrients their body needs and how to get them from food. This thesis will seek to expose the health benefits that are associated with consuming a raw plant-based die, offering a more profound and encompassing view on nutrition. Investigating further into today’s most common diseases such as diabetes, heart disease, obesity, cancer and autoimmune disorders, it will seek to discover and answer why we have so many health issues. This thesis will ...
Neuroprotective Properties Of Phytoestrogens, 2012 University of North Texas Health Science Center at Fort Worth
Neuroprotective Properties Of Phytoestrogens, Courtney Anne Brock
Theses and Dissertations
Women make up nearly two thirds of total Alzheimer’s cases in the United States. It has been speculated that the loss of endogenous estradiol during menopause is, at least in part, what renders the post-menopausal brain more vulnerable to the effects of aging and Alzheimer’s Disease. While hormone therapy can potentially thwart some of the undesirable consequences and increased risks associated with menopause, women are increasingly rejecting hormone therapy and seeking alternative therapy. There is a strong in interest in phytoestrogens as an alternative to traditional hormone therapy.
Phytoestrogens are naturally occurring estrogen like compounds derived from plants ...
Effects Of Planting Date, Harvest Date, And Environmental Conditions On Germination Of Forage Kochia Accessions, 2012 Utah State University
Effects Of Planting Date, Harvest Date, And Environmental Conditions On Germination Of Forage Kochia Accessions, Cody F. Creech
All Graduate Theses and Dissertations
Forage kochia (Bassia prostrata, [L.] A. J. Scott) (Synonym = Kochia prostrata [L.] Schrad.) is a perennial semi-shrub that is valued for its forage quality and ability to restore degraded rangeland. However, establishment success of forage kochia plantings in western North America has been erratic. These failures leave the land vulnerable to erosion and invasion of undesirable plants. This research focused on the germination dynamics of forage kochia accessions as it relates to harvest date, planting date, age of seed, and environmental conditions. The effect of planting date, age of seed, and environmental conditions on forage kochia germination was elucidated by ...