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The Contribution Of Heart Failure To Sleep Disturbances And Depressive Symptoms In Older Adults, Peter Johansson, Barbara Riegel, Erland Svensson, Anders Broström, Urban Alehagen, Ulf Dahlström, Tiny Jaarsma 2012 University of Pennsylvania

The Contribution Of Heart Failure To Sleep Disturbances And Depressive Symptoms In Older Adults, Peter Johansson, Barbara Riegel, Erland Svensson, Anders Broström, Urban Alehagen, Ulf Dahlström, Tiny Jaarsma

School of Nursing Departmental Papers

Background:

The aim of this study was to explore the associations between physical symptoms, sleep disturbances, and depressive symptoms in community-dwelling elderly individuals, comparing persons with and without heart failure (HF).

Methods:

A total of 613 older adults (mean age 78 years) underwent clinical and echocardiographic examinations. Questionnaires were used to evaluate sleep disturbances and depressive symptoms. A model was developed in those with HF (n = 107) and compared with those without HF (n = 506).

Results:

Cardiopulmonary symptoms (ie, dyspnea and nighttime palpitations) and pain had significant direct associations with sleep disturbances, which indirectly affected depressive symptoms. The model was ...


Treatment Of Cardiomyopathy With Pap Therapy In A Patient With Severe Obstructive Sleep Apnea., Ritu G. Grewal, MD 2012 Thomas Jefferson University

Treatment Of Cardiomyopathy With Pap Therapy In A Patient With Severe Obstructive Sleep Apnea., Ritu G. Grewal, Md

Department of Sleep Medicine Faculty Papers

Obstructive sleep apnea is common in patients with heart failure. This case illustrates that treatment with PAP therapy can improve cardiac function in patients with both conditions. CPAP-emergent central apnea, as seen in this patient, has multiple etiologies. It is commonly seen in patients with severe sleep apnea, usually resolves over time, and does not need treatment with adaptive servoventilation.


Factors Associated With Undiagnosed Obstructuve Sleep Apnea In Hypertensive Primary Care Patients, Anders Broström, Ola Sunnergren, Kristofer Årestedt, Peter Johansson, Martin Ulander, Barbara Riegel, Eva Svanborg 2012 University of Pennsylvania

Factors Associated With Undiagnosed Obstructuve Sleep Apnea In Hypertensive Primary Care Patients, Anders Broström, Ola Sunnergren, Kristofer Årestedt, Peter Johansson, Martin Ulander, Barbara Riegel, Eva Svanborg

School of Nursing Departmental Papers

Objective. In hypertensive primary care patients below 65 years of age, (i) to describe the occurrence of undiagnosed obstructive sleep apnoea (OSA), and (ii) to identify the determinants of moderate/severe OSA. Design. Cross-sectional. Setting. Four primary care health centres in Sweden. Patients. 411 consecutive patients (52% women), mean age 57.9 years (SD 5.9 years), with diagnosed and treated hypertension (BP >140/90). Main outcome measures. Occurrence of OSA as measured by the apnoea hypopnoea index (AHI). Results. Mild (AHI 5–14.9/h) and moderate/severe (AHI > 15/h) OSA were seen among 29% and 30% of ...


Obstructive Sleep Apnea Syndrome And Perioperative Complications: A Systematic Review Of The Literature., Tajender S. Vasu, MD, MS, Ritu G. Grewal, MD, Karl Doghramji, MD 2012 Stony Brook University Medical Center, Stony Brook, NY

Obstructive Sleep Apnea Syndrome And Perioperative Complications: A Systematic Review Of The Literature., Tajender S. Vasu, Md, Ms, Ritu G. Grewal, Md, Karl Doghramji, Md

Department of Sleep Medicine Faculty Papers

Obstructive sleep apnea syndrome (OSAS) is a common sleep related breathing disorder. Its prevalence is estimated to be between 2% and 25% in the general population. However, the prevalence of sleep apnea is much higher in patients undergoing elective surgery. Sedation and anesthesia have been shown to increase the upper airway collapsibility and therefore increasing the risk of having postoperative complications in these patients. Furthermore, the majority of patients with sleep apnea are undiagnosed and therefore are at risk during the perioperative period. It is important to identify these patients so that appropriate actions can be taken in a timely ...


Sleep Strategies: Sleep In Women A Changing Perspective, Misha Peter, MD, Ritu G. Grewal, MD 2012 Thomas Jefferson University

Sleep Strategies: Sleep In Women A Changing Perspective, Misha Peter, Md, Ritu G. Grewal, Md

Jefferson Sleep Disorders Center in the News

As with many other specialties, sleep medicine has been shifting toward helping clinicians obtain a better understanding of gender-specific issues in disorders and disturbances. It is easier today to appreciate the complex dynamics of biological, psychosocial, and cultural factors that define sleep patterns and problems in women. Sleep in women changes across their life spans, with three major shifts likely due to hormonal differences: at the onset of the menstrual cycle, during pregnancy, and during the perimenopausal period.


Odor Fear Conditioning Modifies Piriform Cortex Local Field Potentials Both During Conditioning And During Post-Conditioning Sleep, Dylan C. Barnes, Julie Chapuis, Dipesh Chaudhury, Donald A. Wilson 2011 CUNY Graduate Center

Odor Fear Conditioning Modifies Piriform Cortex Local Field Potentials Both During Conditioning And During Post-Conditioning Sleep, Dylan C. Barnes, Julie Chapuis, Dipesh Chaudhury, Donald A. Wilson

Publications and Research

Background: Sleep plays an active role in memory consolidation. Sleep structure (REM/Slow wave activity [SWS]) can be modified after learning, and in some cortical circuits, sleep is associated with replay of the learned experience. While the majority of this work has focused on neocortical and hippocampal circuits, the olfactory system may offer unique advantages as a model system for exploring sleep and memory, given the short, non-thalamic pathway from nose to primary olfactory (piriform cortex), and rapid cortex-dependent odor learning.

Methodology/Principal Findings: We examined piriform cortical odor responses using local field potentials (LFPs) from freely behaving Long-Evans hooded ...


Should Benzodiazepines Be Prescribed To Treat Insomnia And Anxiety Related Disorders?, Judith Nicole Margareten 2011 Touro College

Should Benzodiazepines Be Prescribed To Treat Insomnia And Anxiety Related Disorders?, Judith Nicole Margareten

The Science Journal of the Lander College of Arts and Sciences

The following is an excerpt of the introduction of this article: Benzodiazepines are commonly prescribed drugs used to treat insomnia and anxiety. They are often found in forms such as Xanax (alprazolam) and Valium (diazepam). For many, these drugs have proven essential for ensuring a restful night’s sleep, but for others they are the cause of sleepless ones. Negative effects of benzodiazepines such as addiction, dependence, and impaired cognition plague many patients. While doctors are prone to prescribe these medications readily due to their high level of effectiveness, this practice can pose a great risk to certain populations.


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