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1,092 full-text articles. Page 47 of 49.

Ct Scanning Is Sufficient To Clear The Cervical Spine Of Elderly Falls Less Than 5 Feet., Douglas Lehman MD, Rovinder S. Sandhu MD, Leslie Baga BSN, Farheen Hussain MS, John J. Hong MD 2011 Lehigh Valley Health Network

Ct Scanning Is Sufficient To Clear The Cervical Spine Of Elderly Falls Less Than 5 Feet., Douglas Lehman Md, Rovinder S. Sandhu Md, Leslie Baga Bsn, Farheen Hussain Ms, John J. Hong Md

Administration & Leadership

No abstract provided.


Gender And Bmi Differences In Physical Activity After Total Knee Replacement, Patricia D. Franklin, Wenjun Li, Wenyun Yang, David C. Ayers 2011 University of Massachusetts Medical School

Gender And Bmi Differences In Physical Activity After Total Knee Replacement, Patricia D. Franklin, Wenjun Li, Wenyun Yang, David C. Ayers

UMass Center for Clinical and Translational Science Research Retreat

Background

Total knee replacement (TKR) is an effective procedure to eliminate knee pain due to osteoarthritis. However variation in functional outcome persists. Patient attributes, including age, gender, body mass index (BMI), and emotional health, influence degree of functional gain. The level of daily physical activity (PA) is important to weight management, knee OA care, and overall health. As the arthritis population becomes more overweight and inactive, it is important to understand the physical activity benefits accrued following TKR.

Health promotion programs, conducted in community dwelling adults, have called attention to the use of accelerometers (step activity monitor devices) as a ...


The Use Of Motion Analysis Technology As An Alternative Means Of Assessing Spinal Deformity In Patients With Adolescent Idiopathic Scoliosis, Matthew J. Solomito 2011 University of Connecticut - Storrs

The Use Of Motion Analysis Technology As An Alternative Means Of Assessing Spinal Deformity In Patients With Adolescent Idiopathic Scoliosis, Matthew J. Solomito

Master's Theses

Adolescent Idiopathic Scoliosis (AIS) is a three dimensional deformity of the spine that causes abnormal curvatures in the coronal and sagittal planes and abnormal vertebral rotations. The gold standard for diagnosing and tracking the progression of the deformity is through the use of repeated radiography and a patient can receive upwards of fifteen radiographic series over the course of treatment, which exposes this population to an increased risk of radiation-dependent complications.

This thesis presents the necessary calculations and the marker set required to make the motion capture technology a viable alternative to radiographs, in an effort to reduce the patient ...


Use Of Tranexamic Acid Is A Cost Effective Method In Preventing Blood Loss During And After Total Knee Replacement, Yasir J. Sepah, masood umer, Tashfeen Ahmad, Faria Nasim, Muhammad Umer Chaudhry, Muhammad Umar 2011 Aga Khan University

Use Of Tranexamic Acid Is A Cost Effective Method In Preventing Blood Loss During And After Total Knee Replacement, Yasir J. Sepah, Masood Umer, Tashfeen Ahmad, Faria Nasim, Muhammad Umer Chaudhry, Muhammad Umar

Section of Orthopaedic Surgery

Background & Purpose: Allogenic blood transfusion in elective orthopaedic surgery is best avoided owing to its associated risks. Total knee replacement often requires blood transfusion, more so when bilateral surgery is performed. Many strategies are currently being employed to reduce the amount of peri-operative allogenic transfusions. Anti-fibrinolytic compounds such as aminocaproic acid and tranexamic acid have been used systemically in perioperative settings with promising results. This study aimed to evaluate the effectiveness of tranexamic acid in reducing allogenic blood transfusion in total knee replacement surgery.

Methodology: This was a retrospective cohort study conducted on patients undergoing total knee replacement during the ...


Expansion And Preservation Of Multipotentiality Of Rabbit Bone-Marrow Derived Mesenchymal Stem Cells In Dextran-Based Microcarrier Spin Culture, Tunku Kamarul Zaman 2011 Selected Works

Expansion And Preservation Of Multipotentiality Of Rabbit Bone-Marrow Derived Mesenchymal Stem Cells In Dextran-Based Microcarrier Spin Culture, Tunku Kamarul Zaman

Tunku Kamarul Zaman

The use of mesenchymal stem cells (MSCs) in tissue repair and regeneration despite their multipotentiality has been limited by their cell source quantity and decelerating proliferative yield efficiency. A study was thus undertaken to determine the feasibility of using microcarrier beads in spinner flask cultures for MSCs expansion and compared to that of conventional monolayer cultures and static microcarrier cultures. Isolation and characterization of bone marrow derived MSCs were conducted from six adult New Zealand white rabbits. Analysis of cell morphology on microcarriers and culture plates at different time points (D0, D3, D10, D14) during cell culture were performed using ...


Potent Inhibition Of Heterotopic Ossification By Nuclear Retinoic Acid Receptor-Γ Agonists., Kengo Shimono, Wei-En Tung, Christine Macolino, Amber Hsu-Tsai Chi, Johanna H Didizian, Christina Mundy, Roshantha A Chandraratna, Yuji Mishina, Motomi Enomoto-Iwamoto, Maurizio Pacifici, Masahiro Iwamoto 2011 Thomas Jefferson University College of Medicine

Potent Inhibition Of Heterotopic Ossification By Nuclear Retinoic Acid Receptor-Γ Agonists., Kengo Shimono, Wei-En Tung, Christine Macolino, Amber Hsu-Tsai Chi, Johanna H Didizian, Christina Mundy, Roshantha A Chandraratna, Yuji Mishina, Motomi Enomoto-Iwamoto, Maurizio Pacifici, Masahiro Iwamoto

Department of Orthopaedic Surgery Faculty Papers

Heterotopic ossification consists of ectopic bone formation within soft tissues after surgery or trauma. It can have debilitating consequences, but there is no definitive cure. Here we show that heterotopic ossification was essentially prevented in mice receiving a nuclear retinoic acid receptor-γ (RAR-γ) agonist. Side effects were minimal, and there was no significant rebound effect. To uncover the mechanisms of these responses, we treated mouse mesenchymal stem cells with an RAR-γ agonist and transplanted them into nude mice. Whereas control cells formed ectopic bone masses, cells that had been pretreated with the RAR-γ agonist did not, suggesting that they had ...


A Preliminary Study Comparing The Use Of Allogenic Chondrogenic Pre-Differentiated And Undifferentiated Mesenchymal Stem Cells For The Repair Of Full Thickness Articular Cartilage Defects In Rabbits, Tunku Kamarul Zaman 2011 SelectedWorks

A Preliminary Study Comparing The Use Of Allogenic Chondrogenic Pre-Differentiated And Undifferentiated Mesenchymal Stem Cells For The Repair Of Full Thickness Articular Cartilage Defects In Rabbits, Tunku Kamarul Zaman

Tunku Kamarul Zaman

Chondrogenic differentiated mesenchymal stem cells (CMSCs) have been shown to produce superior chondrogenic expression markers in vitro. However, the use of these cells in vivo has not been fully explored. In this study, in vivo assessment of cartilage repair potential between allogenic-derived chondrogenic pre-differentiated mesenchymal stem cells and undifferentiated MSCs (MSCs) were compared. Bilateral full thickness cartilage defects were created on the medial femoral condyles of 12 rabbits (n = 12). Rabbits were divided into two groups. In one group, the defects in the right knees were repaired using alginate encapsulated MSCs while in the second group, CMSCs were used. The ...


Assessment Of A New Undergraduate Module In Musculoskeletal Medicine., Joseph M. Queally, Fionnan Cummins, Stephen A. Brennan, Martin J. Shelly, John M. O'Byrne 2011 Royal College of Surgeons in Ireland

Assessment Of A New Undergraduate Module In Musculoskeletal Medicine., Joseph M. Queally, Fionnan Cummins, Stephen A. Brennan, Martin J. Shelly, John M. O'Byrne

Trauma and Orthopaedic Surgery Articles

BACKGROUND: Despite the high prevalence of musculoskeletal disorders seen by primary care physicians, numerous studies have demonstrated deficiencies in the adequacy of musculoskeletal education at multiple stages of medical education. The aim of this study was to assess a newly developed module in musculoskeletal medicine for use at European undergraduate level (i.e., the medical-school level).

METHODS: A two-week module in musculoskeletal medicine was designed to cover common musculoskeletal disorders that are typically seen in primary care. The module incorporated an integrated approach, including core lectures, bedside clinical examination, and demonstration of basic practical procedures. A previously validated examination in ...


Platelet-Rich Plasma (Prp) Enhances Bone Healing In Non-United Critical-Sized Defects: A Preliminary Study Involving Rabbit Models, Tunku Kamarul Zaman 2011 SelectedWorks

Platelet-Rich Plasma (Prp) Enhances Bone Healing In Non-United Critical-Sized Defects: A Preliminary Study Involving Rabbit Models, Tunku Kamarul Zaman

Tunku Kamarul Zaman

Introduction: The use of bone grafts in treating non- or delayed unions as the result of large bone loss is well established. However, despite good outcomes, the time to achieve complete union is still considerably long. To overcome this problem, the use of platelet-rich plasma (PRP) has been advocated albeit with varying success. To determine the true effectiveness of PRP in treating non-/delayed unions, a study was conducted using (n = 12) rabbit models. Methods and materials: Critical-sized defects measuring 2 cm created in the midshaft of the right rabbit tibias were stabilised using 2.7-mm small fragment plates. A ...


Biochemical Comparison Of Osteoarthritic Knees With And Without Effusion, Nicole M. Cattano, Jeffrey B. Driban, Easwaran Balasubramanian, Mary F. Barbe, Mamta Amin, Michael R. Sitler 2011 West Chester University of Pennsylvania

Biochemical Comparison Of Osteoarthritic Knees With And Without Effusion, Nicole M. Cattano, Jeffrey B. Driban, Easwaran Balasubramanian, Mary F. Barbe, Mamta Amin, Michael R. Sitler

Sports Medicine

No abstract provided.


Short-Term And Long-Term Effects Of Orthopedic Biodegradable Implants, Ami R. Amini, James S. Wallace, Syam P. Nukavarapu 2011 University of Connecticut School of Medicine and Dentistry

Short-Term And Long-Term Effects Of Orthopedic Biodegradable Implants, Ami R. Amini, James S. Wallace, Syam P. Nukavarapu

Articles - Patient Care

Presently, orthopedic and oral/maxillofacial implants represent a combined $2.8 billion market, a figure expected to experience significant and continued growth. Although traditional permanent implants have been proved clinically efficacious, they are also associated with several drawbacks, including secondary revision and removal surgeries. Non-permanent, biodegradable implants offer a promising alternative for patients, as they provide temporary support and degrade at a rate matching tissue formation, and thus, eliminate the need for secondary surgeries. These implants have been in clinical use for nearly 25 years, competing directly with, or maybe even exceeding, the performance of permanent implants. The initial implantation ...


Investigating The Associations Between Core Strength, Postural Control And Fine Motor Performance In Children, Rachel Burnett, Nicole Cornett, Gina Rekart, Betsy Donahoe-Fillmore, C. Jayne Brahler, Susan Aebker, Megan Kreill 2011 University of Dayton

Investigating The Associations Between Core Strength, Postural Control And Fine Motor Performance In Children, Rachel Burnett, Nicole Cornett, Gina Rekart, Betsy Donahoe-Fillmore, C. Jayne Brahler, Susan Aebker, Megan Kreill

Physical Therapy Faculty Publications

Study design: Quantitative design including statistical analysis.

Objectives: The objective of this study was to determine if there is an association between core strength, postural control, fine motor precision and integration, specifically in typical children in the first and third grades, ages 6-10. The secondary purpose of this study was to determine if there was an association between BMI and fine and gross motor ability in this same population.

Background: The relationship between core strength, postural control and fine motor skills in children is not well understood. The assumption that trunk stability and control are necessary for the maturation of ...


A Preliminary Study Of The Effects Of Glucosamine Sulphate And Chondroitin Sulphate On Surgically Treated And Untreated Focal Cartilage Damage, Tunku Kamarul Zaman 2011 SelectedWorks

A Preliminary Study Of The Effects Of Glucosamine Sulphate And Chondroitin Sulphate On Surgically Treated And Untreated Focal Cartilage Damage, Tunku Kamarul Zaman

Tunku Kamarul Zaman

The effects of Glucosamine Sulphate (GS) and Chondroitin Sulphate (CS) on the healing of damaged and repaired articular cartilage were investigated. This study was conducted using 18 New Zealand white rabbits as experimental models. Focal cartilage defects, surgically created in the medial femoral condyle, were either treated by means of autologous chondrocyte implantation (ACI) or left untreated as controls. Rabbits were then divided into groups which received either GS+/-CS or no pharmacotherapy. Three rabbits from each group were sacrificed at 12 and 24 weeks post-surgery. Knees dissected from rabbits were then evaluated using gross quantification of repair tissue, glycosaminoglycan ...


Knee Range Of Motion: Reliability And Agreement Of 3 Measurement Methods, Paul G. Peters, Michael A. Herbenick, Philip A. Anloague, Ronald J. Markert, L. Joseph Rubino 2011 Wright State University - Main Campus

Knee Range Of Motion: Reliability And Agreement Of 3 Measurement Methods, Paul G. Peters, Michael A. Herbenick, Philip A. Anloague, Ronald J. Markert, L. Joseph Rubino

Physical Therapy Faculty Publications

We conducted a study to compare 3 methods of measuring knee range of motion: visual estimation by physicians, hand goniometry by physical therapists, and radiographic goniometry. We hypothesized that reliability would be high within and across all techniques. We found intrarater and interrater reliability to be satisfactory for visual estimation, hand goniometry, and radiographic goniometry. Interrater reliability across methods did not agree satisfactorily. Between-methods differences in estimating knee range of motion may result from variations in technique among physicians and physical therapists.


A Comparison Of Two Pelvic Floor Muscle Training Programs In Females With Stress Urinary Incontinence: A Pilot Study, Betsy Donahoe-Fillmore, Wendy Chorny, C. Jayne Brahler, Ashley Ingley, Jennifer Kennedy, Valerie Osterfeld 2011 University of Dayton

A Comparison Of Two Pelvic Floor Muscle Training Programs In Females With Stress Urinary Incontinence: A Pilot Study, Betsy Donahoe-Fillmore, Wendy Chorny, C. Jayne Brahler, Ashley Ingley, Jennifer Kennedy, Valerie Osterfeld

Physical Therapy Faculty Publications

Background: Stress urinary incontinence (SUI) is a condition affecting millions of Americans. Few studies have assessed the benefits of different exercises involved in pelvic floor muscle training (PFMT). Purposte: The purpose of this study was to compare the effects of a traditional PFMT program to an assisted pelvic floor muscle training (APFMT) program that included contraction of hip musculature.


Using Cardiopulmonary Exercise Testing To Evaluate Fatigue And Post-Exertional Malaise In Me/Cfs, Christopher R. Snell, Staci R. Stevens, Todd E. Davenport, J. Mark VanNess 2011 University of the Pacific

Using Cardiopulmonary Exercise Testing To Evaluate Fatigue And Post-Exertional Malaise In Me/Cfs, Christopher R. Snell, Staci R. Stevens, Todd E. Davenport, J. Mark Vanness

School of Pharmacy and Health Sciences Faculty Articles

No abstract provided.


The Infected Hip: A Treatment Algorithm, Bahar Adeli, Javad Parvizi MD 2011 Rothman Institute, Thomas Jefferson University Hospital

The Infected Hip: A Treatment Algorithm, Bahar Adeli, Javad Parvizi Md

Department of Orthopaedic Surgery Faculty Papers

The management of periprosthetic joint infection following total joint arthroplasty is presently a major challenge to orthopedic surgeons. Despite various treatment options available, the two-stage revision procedure is most often chosen in North America because of a high success rate, especially in cases involving resistant organisms. Sometimes the use of antibiotics alone, irrigation with debridement, or a one-stage exchange may be a more appropriate treatment option. Various factors such as the status of a patient’s immune system, time of onset of the infection, as well as susceptibility of causative microorganism should be considered as they play an important role ...


Effects Of Lateral Ligament Sectioning On The Stability Of The Ankle And Subtalar Joint, Stacie I. Ringleb, Ajaya Dhakal, Claude D. Anderson, Sebastian Bawab, Rajesh Paranjape 2011 Old Dominion University

Effects Of Lateral Ligament Sectioning On The Stability Of The Ankle And Subtalar Joint, Stacie I. Ringleb, Ajaya Dhakal, Claude D. Anderson, Sebastian Bawab, Rajesh Paranjape

Mechanical & Aerospace Engineering Faculty Publications

Patients with subtalar joint instability are often diagnosed with ankle instability. Only after a prolonged period of time in which a patient does not improve after treatment for ankle instability is subtalar joint instability considered. To develop a clinically relevant method to diagnose subtalar joint instability, the kinematics of the simulated unstable subtalar joint were examined. A 6 degree-of-freedom positioning and loading device was developed. Plantarflexion/dorsiflexion, inversion/eversion, and internal/external rotation were applied individually or as coupled motions along with an anterior/posterior drawer. Kinematic data were collected from sensors attached to the calcaneus, talus, and tibia by ...


Arthroscopic Repair Of Meniscal Tears With Inside-Out Technique, Hasnain Raza, Kashif Abbas, Masood Umer 2011 Aga Khan University

Arthroscopic Repair Of Meniscal Tears With Inside-Out Technique, Hasnain Raza, Kashif Abbas, Masood Umer

Section of Orthopaedic Surgery

OBJECTIVE: To review the clinical results of arthroscopic meniscal repair and to identify factors that may affect the outcome.

METHODS: A total of 15 arthroscopic meniscal repairs with inside-out in 14 patients over a 7-year period were evaluated retrospectively. The mean age was 41.2 +/- 11.5 years with a range of 26-64 years. Eleven patients underwent repair for medial meniscal tear, two patients for lateral meniscus and one patient for both in the same knee. All patients were functionally evaluated by Lysholm functional knee scores over an average follow-up of 1 year and 5 months (range: 0.5-7 years ...


Neurologic Improvement After Thoracic, Thoracolumbar, And Lumbar Spinal Cord (Conus Medullaris) Injuries, James S. Harrop, MD, Swetha Naroji, Mitchell G. Maltenfort, PhD, John K. Ratliff, MD, Stavropoula L. Tjoumakaris, Brian Frank, D. Greg Anderson, M.D., Todd Albert, MD, Alexander R. Vaccaro, MD, PhD 2011 Thomas Jefferson University Hospital

Neurologic Improvement After Thoracic, Thoracolumbar, And Lumbar Spinal Cord (Conus Medullaris) Injuries, James S. Harrop, Md, Swetha Naroji, Mitchell G. Maltenfort, Phd, John K. Ratliff, Md, Stavropoula L. Tjoumakaris, Brian Frank, D. Greg Anderson, M.D., Todd Albert, Md, Alexander R. Vaccaro, Md, Phd

Department of Orthopaedic Surgery Faculty Papers

Study Design. Retrospective. Objective. With approximately 10,000 new spinal cord injury (SCI) patients in the United States each year, predicting public health outcomes is an important public health concern. Combining all regions of the spine in SCI trials may be misleading if the lumbar and sacral regions (conus) have a neurologic improvement at different rates than the thoracic or thoracolumbar spinal cord.

Summary of Background Data. Over a 10-year period between January 1995 to 2005, 1746 consecutive spinal injured patients were seen, evaluated, and treated through a level 1 trauma referral center. A retrospective analysis was performed on 150 ...


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