Energy And Protein Requirements For Children With Ckd Stages 2-5 And On Dialysis-Clinical Practice Recommendations From The Pediatric Renal Nutrition Taskforce., 2020 Children's Mercy Hospital
Energy And Protein Requirements For Children With Ckd Stages 2-5 And On Dialysis-Clinical Practice Recommendations From The Pediatric Renal Nutrition Taskforce., Vanessa Shaw, Nonnie Polderman, José Renken-Terhaerdt, Fabio Paglialonga, Michiel Oosterveld, Jetta Tuokkola, Caroline Anderson, An Desloovere, Laurence Greenbaum, Dieter Haffner, Christina Nelms, Leila Qizalbash, Johan Vande Walle, Bradley A. Warady, Rukshana Shroff, Lesley Rees
Manuscripts, Articles, Book Chapters and Other Papers
Dietary management in pediatric chronic kidney disease (CKD) is an area fraught with uncertainties and wide variations in practice. Even in tertiary pediatric nephrology centers, expert dietetic input is often lacking. The Pediatric Renal Nutrition Taskforce (PRNT), an international team of pediatric renal dietitians and pediatric nephrologists, was established to develop clinical practice recommendations (CPRs) to address these challenges and to serve as a resource for nutritional care. We present CPRs for energy and protein requirements for children with CKD stages 2-5 and those on dialysis (CKD2-5D). We address energy requirements in the context of poor growth, obesity, and different …
The Dietary Management Of Calcium And Phosphate In Children With Ckd Stages 2-5 And On Dialysis-Clinical Practice Recommendation From The Pediatric Renal Nutrition Taskforce., 2020 Children's Mercy Hospital
The Dietary Management Of Calcium And Phosphate In Children With Ckd Stages 2-5 And On Dialysis-Clinical Practice Recommendation From The Pediatric Renal Nutrition Taskforce., Louise Mcalister, Pearl Pugh, Laurence Greenbaum, Dieter Haffner, Lesley Rees, Caroline Anderson, An Desloovere, Christina Nelms, Michiel Oosterveld, Fabio Paglialonga, Nonnie Polderman, Leila Qizalbash, José Renken-Terhaerdt, Jetta Tuokkola, Bradley A. Warady, Johan Vande Walle, Vanessa Shaw, Rukshana Shroff
Manuscripts, Articles, Book Chapters and Other Papers
In children with chronic kidney disease (CKD), optimal control of bone and mineral homeostasis is essential, not only for the prevention of debilitating skeletal complications and achieving adequate growth but also for preventing vascular calcification and cardiovascular disease. Complications of mineral bone disease (MBD) are common and contribute to the high morbidity and mortality seen in children with CKD. Although several studies describe the prevalence of abnormal calcium, phosphate, parathyroid hormone, and vitamin D levels as well as associated clinical and radiological complications and their medical management, little is known about the dietary requirements and management of calcium (Ca) and …
Remarks About The Study On Infection-Associated Relapses In Children With Nephrotic Syndrome: A Short-Term Outcome Study, 2020 Aga Khan University
Remarks About The Study On Infection-Associated Relapses In Children With Nephrotic Syndrome: A Short-Term Outcome Study, Akbar Shoukat Ali, Raheel Allana, Rahim Jandani
Department of Medicine
No abstract provided.
Oxidant Stress And Renal Function Among Children With Chronic Kidney Disease: A Repeated Measures Study., 2020 Children's Mercy Hospital
Oxidant Stress And Renal Function Among Children With Chronic Kidney Disease: A Repeated Measures Study., Melanie H. Jacobson, Mengling Liu, Yinxiang Wu, Susan Furth, Bradley A. Warady, Howard Trachtman, Leonardo Trasande
Manuscripts, Articles, Book Chapters and Other Papers
It is hypothesized that chronic kidney disease (CKD) induces oxidant stress which contributes to the decline in kidney function. However, few studies have incorporated longitudinal designs and no studies have investigated this association among children. Using data from the Chronic Kidney Disease in Children (CKiD) study, we examined longitudinal associations between urinary biomarkers of oxidant stress, 8-OH deoxyguanosine (8-OHdG) and F2-isoprostane, and measures of renal function and blood pressure among children with CKD. Baseline levels of 8-OHdG were positively associated with estimated glomerular filtration rate (eGFR) over time and a log-unit increase in baseline 8-OHdG predicted a 5.68 ml/min/1.73 m2 …
Adequacy Of Hemodialysis And Its Associated Factors Among Patients Undergoing Chronic Hemodialysis In Dar Es Salaam, Tanzania, 2020 Aga Khan University
Adequacy Of Hemodialysis And Its Associated Factors Among Patients Undergoing Chronic Hemodialysis In Dar Es Salaam, Tanzania, Samina Somji, Pascal Ruggajo, Sibtain Moledina
Internal Medicine, East Africa
The worldwide prevalence of maintenance hemodialysis continues to rise. An adequate delivery of hemodialysis dose as measured by Kt/V or urea reduction ratio is a crucial determinant of clinical outcome for chronic hemodialysis patients. )e aim of this study was to assess the adequacy of hemodialysis and its associated factors among patients undergoing chronic hemodialysis in Dar es Salaam. )is was a cross-sectional study done on patients undergoing chronic hemodialysis in four dialysis centers in Dar es Salaam. Sociodemographic information and treatment characteristics were collected. Urea reduction rate and single-pool Kt/V were calculated to determine the adequacy of hemodialysis. )e …
Association Of Time-Varying Blood Pressure With Chronic Kidney Disease Progression In Children., 2020 Children's Mercy Hospital
Association Of Time-Varying Blood Pressure With Chronic Kidney Disease Progression In Children., Ben Christopher Reynolds, Jennifer Lynn Roem, Derek Kai Sing Ng, Mina Matsuda-Abedini, Joseph Thomas Flynn, Susan Lynn Furth, Bradley A. Warady, Rulan Savita Parekh
Manuscripts, Articles, Book Chapters and Other Papers
Importance: Optimal blood pressure (BP) management in children with chronic kidney disease (CKD) slows progression to end-stage renal disease. Studies often base progression risk on a single baseline BP measurement, which may underestimate risk.
Objective: To determine whether time-varying BP measurements are associated with a higher risk of progression of CKD than baseline BP measurements.
Design, Setting, and Participants: The ongoing longitudinal, prospective cohort study Chronic Kidney Disease in Children (CKID) recruited children from January 19, 2005, through March 19, 2014, from pediatric nephrology centers across North America, with data collected at annual study visits. Participants included children aged 1 …
Calcium Alkali Thiazide Syndrome, 2020 HCA Healthcare
Calcium Alkali Thiazide Syndrome, Mehboob A. Rehan Md, Asma Rashid Md, Reema Singh Md, Gabutti Cristina, Luma Mohsin Md, Tausha Allen Md, Paul Stanford Md, James Thomson Md
Internal Medicine
No abstract provided.
Acute Kidney Injury In Patients Hospitalized With Covid-19, 2020 Zucker School of Medicine at Hofstra/Northwell
Acute Kidney Injury In Patients Hospitalized With Covid-19, J. S. Hirsch, J. H. Ng, D. W. Ross, H. H. Shah, R. L. Barnett, A. D. Hazzan, S. Fishbane, K. D. Jhaveri, M. Abate, A. Bellucci, M. C. Bhaskaran, M. Gitman, C. Halinski, S. Hasan, S. Hong, Y. Khanin, A. Kuan, V. Madireddy, D. Malieckal, A. Muzib
Journal Articles
© 2020 International Society of Nephrology The rate of acute kidney injury (AKI) associated with patients hospitalized with Covid-19, and associated outcomes are not well understood. This study describes the presentation, risk factors and outcomes of AKI in patients hospitalized with Covid-19. We reviewed the health records for all patients hospitalized with Covid-19 between March 1, and April 5, 2020, at 13 academic and community hospitals in metropolitan New York. Patients younger than 18 years of age, with end stage kidney disease or with a kidney transplant were excluded. AKI was defined according to KDIGO criteria. Of 5,449 patients admitted …
Covid-19 In Kidney Transplant Recipients, 2020 Zucker School of Medicine at Hofstra/Northwell
Covid-19 In Kidney Transplant Recipients, V. Nair, N. Jandovitz, J. S. Hirsch, G. Nair, M. Abate, M. Bhaskaran, E. Grodstein, I. Berlinrut, D. Hirschwerk, S. L. Cohen, K. W. Davidson, A. J. Dominello, G. A. Osorio, S. Richardson, L. W. Teperman, E. P. Molmenti
Journal Articles
No abstract provided.
Mir193a Modulation And Podocyte Phenotype, 2020 Northwell Health
Mir193a Modulation And Podocyte Phenotype, A. Jha, S. Saha, K. Ayasolla, H. Vashistha, A. Malhotra, K. Skorecki, P. C. Singhal
Journal Articles
Apolipoprotein L1 (APOL1)-miR193a axis has been reported to play a role in the maintenance of podocyte homeostasis. In the present study, we analyzed transcription factors relevant to miR193a in human podocytes and their effects on podocytes' molecular phenotype. The motif scan of the miR193a gene provided information about transcription factors, including YY1, WT1, Sox2, and VDR-RXR heterodimer, which could potentially bind to the miR193a promoter region to regulate miR193a expression. All structure models of these transcription factors and the tertiary structures of the miR193a promoter region were generated and refined using computational tools. The DNA-protein complexes of the miR193a promoter …
Inflammation And Erythropoiesis-Stimulating Agent Hyporesponsiveness: A Critical Connection, 2020 Zucker School of Medicine at Hofstra/Northwell
Inflammation And Erythropoiesis-Stimulating Agent Hyporesponsiveness: A Critical Connection, H. H. Shah, N. N. Uppal, S. Fishbane
Journal Articles
No abstract provided.
Erythropoiesis-Stimulating Agent Treatment In Patients With Covid-19., 2020 Zucker School of Medicine at Hofstra/Northwell
Erythropoiesis-Stimulating Agent Treatment In Patients With Covid-19., S. Fishbane, J. S. Hirsch
Journal Articles
No abstract provided.
Covid-19 Therapeutic Options For Patients With Kidney Disease, 2020 Zucker School of Medicine at Hofstra/Northwell
Covid-19 Therapeutic Options For Patients With Kidney Disease, H. Izzedine, K. D. Jhaveri, M. A. Perazella
Journal Articles
No abstract provided.
Novel Approaches To Arteriovenous Access Creation, Maturation, Suitability, And Durability For Dialysis, 2020 Zucker School of Medicine at Hofstra/Northwell
Novel Approaches To Arteriovenous Access Creation, Maturation, Suitability, And Durability For Dialysis, M. V. Devita, S. K. Khine, H. Shivarov
Journal Articles
© 2020 Since the arteriovenous fistula (AVF) was first conceived over 50 years ago, the goal to create a vascular conduit with predictable and reproducible maturation and durability continues to elude caregivers. Recently, however, advances in the understanding of vascular biology and new technologies now provides us with some optimism; we are moving toward a viable solution. A quickly maturing, sustainable, and durable arteriovenous access may soon be attainable. This review will discuss these advances. There are novel approaches to AVF creation and devices to enhance maturation, advances in arteriovenous graft material(s), and devices to safely prolong the use of …
Randomized Controlled Trial Of Difelikefalin For Chronic Pruritus In Hemodialysis Patients, 2020 Zucker School of Medicine at Hofstra/Northwell
Randomized Controlled Trial Of Difelikefalin For Chronic Pruritus In Hemodialysis Patients, S. Fishbane, V. Mathur, M. J. Germain, S. Shirazian, S. Bhaduri, C. Munera, R. H. Spencer, F. Menzaghi
Journal Articles
No abstract provided.
Thrombotic Microangiopathy In A Patient With Covid-19., 2020 Zucker School of Medicine at Hofstra/Northwell
Thrombotic Microangiopathy In A Patient With Covid-19., Kd Jhaveri, Lr Meir, Bs Flores Chang, R Parikh, R Wanchoo, Ml Barilla-Labarca, V Bijol, N Hajizadeh
Journal Articles
No abstract provided.
Clinically Significant Anticardiolipin Antibodies Associated With Covid-19, 2020 Northwell Health
Clinically Significant Anticardiolipin Antibodies Associated With Covid-19, S Hossri, M Shadi, Z Hamarsha, R Schneider, D El-Sayegh
Journal Articles
No abstract provided.
Acute Kidney Injury In Patients With Covid-19: An Update On The Pathophysiology., 2020 Zucker School of Medicine at Hofstra/Northwell
Acute Kidney Injury In Patients With Covid-19: An Update On The Pathophysiology., H. Izzedine, K. D. Jhaveri
Journal Articles
No abstract provided.
Covid-19 And Solid Organ Transplant Outcomes, 2020 Zucker School of Medicine at Hofstra/Northwell
Covid-19 And Solid Organ Transplant Outcomes, V. Nair, N. Jandovitz, K. D. Jhaveri, E. Molmenti
Journal Articles
No abstract provided.
Covid-19 In Hospitalized Patients On Chronic Peritoneal Dialysis: A Case Series, 2020 Zucker School of Medicine at Hofstra/Northwell
Covid-19 In Hospitalized Patients On Chronic Peritoneal Dialysis: A Case Series, M. Sachdeva, N. N. Uppal, J. S. Hirsch, J. H. Ng, D. Malieckal, S. Fishbane, K. D. Jhaveri
Journal Articles
No abstract provided.