Csf Protein Changes Associated With Hippocampal Sclerosis Risk Gene Variants Highlight Impact Of Grn/Pgrn, 2017 University of Kentucky
Csf Protein Changes Associated With Hippocampal Sclerosis Risk Gene Variants Highlight Impact Of Grn/Pgrn, David W. Fardo, Yuriko Katsumata, John S. K. Kauwe, Yuetiva Deming, Oscar Harari, Carlos Cruchaga, Alzheimer’S Disease Neuroimaging Initiative, Peter T. Nelson
Sanders-Brown Center on Aging Faculty Publications
Objective—Hippocampal sclerosis of aging (HS-Aging) is a common cause of dementia in older adults. We tested the variability in cerebrospinal fluid (CSF) proteins associated with previously identified HS-Aging risk single nucleotide polymorphisms (SNPs).
Methods—Alzheimer’s Disease Neuroimaging Initiative cohort (ADNI; n=237) data, combining both multiplexed proteomics CSF and genotype data, were used to assess the association between CSF analytes and risk SNPs in four genes (SNPs): GRN (rs5848), TMEM106B (rs1990622), ABCC9 (rs704180), and KCNMB2 (rs9637454). For controls, non-HS-Aging SNPs in APOE (rs429358/rs7412) and MAPT (rs8070723) were also analyzed against Aβ1-42 and total tau CSF analytes.
Results—The GRN risk …
Perceptions Of Successful Aging Among Maine Elders With Physical Limitations: Insights From Qualitative Interviews, 2017 University of Southern Maine
Perceptions Of Successful Aging Among Maine Elders With Physical Limitations: Insights From Qualitative Interviews, Madeline Minor, Rebecca Knight
Thinking Matters Symposium Archive
Research Question: How do elders living with a disability perceive the aging process?
Role Of Domiciliary And Family Carers In Individualised Nutrition Support For Older Adults Living In The Community, 2017 Bond University
Role Of Domiciliary And Family Carers In Individualised Nutrition Support For Older Adults Living In The Community, Skye Marshall, Ekta Agarwal, Adrienne Young, Liz Isenring
Liz Isenring
Role Of Domiciliary And Family Carers In Individualised Nutrition Support For Older Adults Living In The Community, 2017 Bond University
Role Of Domiciliary And Family Carers In Individualised Nutrition Support For Older Adults Living In The Community, Skye Marshall, Ekta Agarwal, Adrienne Young, Liz Isenring
Skye Marshall
Role Of Domiciliary And Family Carers In Individualised Nutrition Support For Older Adults Living In The Community, 2017 Bond University
Role Of Domiciliary And Family Carers In Individualised Nutrition Support For Older Adults Living In The Community, Skye Marshall, Ekta Agarwal, Adrienne Young, Liz Isenring
Ekta Agarwal
The Slps Role In Caring For The Adult And Geriatric Populations, 2017 East Tennessee State University
The Slps Role In Caring For The Adult And Geriatric Populations, Courtney M. Andrews
ETSU Faculty Works
- Define the SLP role with patients commonly seen in primary care
- Duplicate SLP knowledge to help in primary care
- Evaluate the role of the SLP as part of the multidisciplinary team
Tuning Up The Old Brain With New Tricks: Attention Training Via Neurofeedback, 2017 University of Kentucky
Tuning Up The Old Brain With New Tricks: Attention Training Via Neurofeedback, Yang Jiang, Reza Abiri, Xiaopeng Zhao
Sanders-Brown Center on Aging Faculty Publications
Neurofeedback (NF) is a form of biofeedback that uses real-time (RT) modulation of brain activity to enhance brain function and behavioral performance. Recent advances in Brain-Computer Interfaces (BCI) and cognitive training (CT) have provided new tools and evidence that NF improves cognitive functions, such as attention and working memory (WM), beyond what is provided by traditional CT. More published studies have demonstrated the efficacy of NF, particularly for treating attention deficit hyperactivity disorder (ADHD) in children. In contrast, there have been fewer studies done in older adults with or without cognitive impairment, with some notable exceptions. The focus of this …
Delirium Recognition In Hospitalized Older Patients: A Quality Improvement Project, 2017 Department of Geriatrics, Aurora Health Care
Delirium Recognition In Hospitalized Older Patients: A Quality Improvement Project, Jodi Punke, Ariba Khan, Michael L. Malone
Jodi Punke
Background: We noted a low reported prevalence of delirium (3%) in hospitalized older patients at a community teaching hospital in north central Wisconsin.
Purpose: This was a quality improvement project to report recognition of delirium by nurses before and after an educational intervention.
Methods: This project was performed on one medical unit in our hospital. Quality improvement data was collected at baseline and after the educational intervention. Data collected included observation by a geriatrician attending weekly interdisciplinary rounds to note any mention by nurses of delirium or confusion. The patient’s electronic health record (EHR) was reviewed to note delirium assessment …
Adverse Events And Treatment Discontinuations Of Antimuscarinics For The Treatment Of Overactive Bladder In Older Adults: A Systematic Review And Meta-Analysis, 2017 St. Louis College of Pharmacy
Adverse Events And Treatment Discontinuations Of Antimuscarinics For The Treatment Of Overactive Bladder In Older Adults: A Systematic Review And Meta-Analysis, Scott Martin Vouri, Clark D. Kebodeaux, Paul M. Stranges, Besu F. Teshome
Pharmacy Practice and Science Faculty Publications
Introduction
Antimuscarinics should be used with caution in older adults with overactive bladder (OAB) due to anticholinergic adverse events (AEs). Systematic reviews and meta-analyses (SRMAs) have analyzed safety-related outcomes but have not specified risk in the elderly, the population at highest risk for AEs. The aim of this review is to explore and evaluate AEs and treatment discontinuations in adults 65 or older taking antimuscarinics for OAB.
Methods
Keywords were searched in MEDLINE, EMBASE, SCOPUS, and Cochrane Central Register for Controlled Trials. Randomized controlled trials (RCTs) along with sub-analyses and pooled analyses that compared antimuscarinics to placebo or another antimuscarinic …
Osteoporosis Treatment Efficacy For Men: A Systematic Review And Meta-Analysis., 2017 Swedish Center for Research and Innovation, Swedish Health Services, Swedish Medical Center, Seattle, Washington
Osteoporosis Treatment Efficacy For Men: A Systematic Review And Meta-Analysis., Smita Nayak, Susan L Greenspan
Articles, Abstracts, and Reports
OBJECTIVES: To evaluate the efficacy of treatment options to reduce osteoporotic fracture risk in men.
DESIGN: Systematic review and meta-analysis.
SETTING: Randomized clinical trials that evaluated the efficacy of a treatment for osteoporosis or low bone mineral density for adult men and reported fracture outcomes.
PARTICIPANTS: Men.
MEASUREMENTS: PubMed, Embase, and the Cochrane Library databases were searched for relevant studies. Information was extracted from included studies on participant sociodemographic characteristics, number of male participants, treatment evaluated, comparator for evaluated treatment, study duration, and fracture outcomes. Risk of bias of individual studies was assessed using measures recommended by the Cochrane Collaboration. …
Comparison Of The Hui3 And The Eq-5d-3l In A Nursing Home Setting, 2017 Edith Cowan University
Comparison Of The Hui3 And The Eq-5d-3l In A Nursing Home Setting, Tom Lung, Kirsten Howard, Christopher Etherton-Beer, Moira Sim, Gill Lewin, Glenn Arendts
Research outputs 2014 to 2021
Background:
Accurately assessing changes in the quality of life of older people living permanently in nursing homes is important. The multi-attribute utility instrument most commonly used and recommended to assess health-related quality of life in the nursing home population is the three-level EuroQol EQ-5D-3L. To date, there have been no studies using the Health Utilities Index Mark III (HUI3). The purpose of this study was to compare the level of agreement and sensitivity to change of the EQ-5D-3L and HUI3 in a nursing home population.
Methods:
EQ-5D-3L and HUI3 scores were measured as part of a cluster randomised controlled trial …
Disability In Long-Term Care Residents Explained By Prevalent Geriatric Syndromes, Not Long-Term Care Home Characteristics: A Cross-Sectional Study, 2017 University of Toronto
Disability In Long-Term Care Residents Explained By Prevalent Geriatric Syndromes, Not Long-Term Care Home Characteristics: A Cross-Sectional Study, Natasha E. Lane, Walter P. Wodchis, Cynthia M. Boyd, Thérèse A. Stukel
Dartmouth Scholarship
Self-care disability is dependence on others to conduct activities of daily living, such as bathing, eating and dressing. Among long-term care residents, self-care disability lowers quality of life and increases health care costs. Understanding the correlates of self-care disability in this population is critical to guide clinical care and ongoing research in Geriatrics. This study examines which resident geriatric syndromes and chronic conditions are associated with residents’ self-care disability and whether these relationships vary across strata of age, sex and cognitive status. It also describes the proportion of variance in residents’ self-care disability that is explained by residents’ geriatric syndromes …
Building Connected Communities: Reducing Loneliness And Social Isolation In Immigrants 65+ – February 2017 – Research Update, 2017 Sheridan College
Building Connected Communities: Reducing Loneliness And Social Isolation In Immigrants 65+ – February 2017 – Research Update, Sheridan Centre For Elder Research
Publications and Scholarship
Sheridan Centre for Elder Research received a three year grant from the Social Sciences and Humanities Research Council (SSHRC) to explore new strategies to effectively reach and service immigrants age 65+ who may be experiencing, or are at risk of experiencing loneliness and/or social isolation. Research Update - Issue 3 (February, 2017) highlights the research team's progress and an invitation for interested organizations to participate in the research.
Uncovering The Lived Experience Of Community-Dwelling Jewish Women Over 80 Who Self-Identify As Aging Successfully: A Phenomenological Study, 2017 University of Vermont
Uncovering The Lived Experience Of Community-Dwelling Jewish Women Over 80 Who Self-Identify As Aging Successfully: A Phenomenological Study, Rebecca Fredman
Graduate College Dissertations and Theses
Background: Although there is significant scholarly interest in defining the concept of successful aging, there are very few small-scale, in-depth qualitative studies examining the lived experience of women over 80 who self-identify as aging successfully.
Aim: The aim of this study is to explore the lived experience of a small group of community-dwelling Jewish women over 80 in a single county in Northwestern Vermont who self-identify as aging successfully.
Approach: This study has a phenomenological approach.
Method: Phenomenological interviews were conducted with five women over 80 years of age. Interview content was analyzed, and shared themes were synthesized.
Findings: Findings …
Healthy Aging Website: Providing Online Occupation Based Information, 2017 Dominican University of California
Healthy Aging Website: Providing Online Occupation Based Information, Haley Caruthers, Samantha Talavera, Stephanie Vera, Jackeline Ulloa
Student Research Posters
Older adults (OAs) over the age of 65 are the fastest growing age group in the United States. They are also the fastest growing population of Internet users as they use the Internet to access health information related to optimizing independence, productivity, and social engagement. Although there is an abundant amount of information available that is devoted to healthy aging, the validity of the information can be questionable and the information may be confusing.
Dominican University of California’s (DUC) Healthy Aging website contains relevant and evidence-based research, including activities and local community based programs that promote healthy aging. To expand …
Meeting Aging-Related Needs In 2016, 2017 Virginia Commonwealth University
Meeting Aging-Related Needs In 2016, Edward F. Ansello
Director's Editorials from Age in Action
Our Virginia Center on Aging has four program focuses. These programs are: dementia, elder abuse and domestic violence in later life, geriatrics education, and lifelong learning. Each achieved substantially in calendar 2016.
Abuse And Neglect Of Animals And People, An Update, 2017 Virginia Commonwealth University
Abuse And Neglect Of Animals And People, An Update, Edward F. Ansello
Director's Editorials from Age in Action
Veterinarians have noticed for quite some time that individuals who mistreat their animals may not stop there, carrying over their behavior to spouses, parents and others. Research articles and “overview” publications have increased in number, as have advocacy groups and just the beginnings of connections between domestic violence and animal rights groups.
Oral Health And Aging, 2017 Virginia Commonwealth University
Oral Health And Aging, Edward F. Ansello
Director's Editorials from Age in Action
The sooner we recognize the importance of oral health to our well-being as older adults, the better we age. We need to consider our dentist as part of our health care team. For those of us in health professions, we should work together more to incorporate oral health into primary care.
Laughter And Well Being As We Age, 2017 Virginia Commonwealth University
Laughter And Well Being As We Age, Edward F. Ansello
Director's Editorials from Age in Action
Laughing at mistakes is demonstrably healthy. As we get older, we have accumulated a lifetime of mistakes. Humor and laughter, laughing at ourselves or our circumstances, can be therapeutic.
Safe Driving For The Mature Adult: Selected Issues, 2017 Virginia Department of Motor Vehicles
Safe Driving For The Mature Adult: Selected Issues, Rebecca Parsio
Case Studies from Age in Action
Educational Objectives
1. Examine issues related to aging and driving assessment.
2. Review Virginia’s Mature Drivers Study.
3. Discuss the levels of care for prevention of driving disability and resources available at each level.
4. Explore the impact of medications and substances (both prescribed and not prescribed) on driving ability.