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Using A Single Tablet Regimen Of Darunavir, Cobicistat, Emcitrabine, And Tenofovir Alafenamide In Virally Suppressed Hiv-1 Patients Is An Adequate Treatment Option For Controlling Hiv, Priya Kathuria 2021 Wayne State University School of Medicine

Using A Single Tablet Regimen Of Darunavir, Cobicistat, Emcitrabine, And Tenofovir Alafenamide In Virally Suppressed Hiv-1 Patients Is An Adequate Treatment Option For Controlling Hiv, Priya Kathuria

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using:

Orkin C, Molina JM, Negredo E, et al. Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial. Lancet HIV. 2018;5(1):e23-e34. https://doi.org/10.1016/S2352-3018(17)30179-0

for a patient with viriologically suppressed HIV-1.


Effect Of Presence And Absence Of Parents On The Emotional Maturity And Perceived Loneliness In Adolescents, Sana Fatima, Momal Bashir, Kainat Khan, Sheeza Farooq, Sidra Shoaib, Sheeba Farhan 2021 BAHRIA UNIVERSITY, KARACHI CAMPUS, NATIONAL STADIUM RD, KARACHI, PAKISTAN

Effect Of Presence And Absence Of Parents On The Emotional Maturity And Perceived Loneliness In Adolescents, Sana Fatima, Momal Bashir, Kainat Khan, Sheeza Farooq, Sidra Shoaib, Sheeba Farhan

Journal of Mind and Medical Sciences

The present study was conducted to examine the Emotional Maturity and Perceived Loneliness of adolescents with respect to the presence and absence of parents. It was hypothesized that the absence or presence of parents of adolescents would affect the level of emotional maturity and perceived loneliness among adolescents. The adolescent participants N=250 (males n=125 and females n=125; age range= 13-18; M=16.63; SD=0.87) were approached through purposive convenient sampling technique. Measures included the Emotional Maturity Scale and the UCLA loneliness scale V-III. Results indicated that adolescent who lived with their guardians had greater perceived loneliness than those who lived with their …


Adverse Childhood Experiences And Urinary Incontinence In Elementary School Aged Children, Amanda Jill Travis MSN, FNP-C, Margaret C. Harvey PhD, APRN, ACNP-BC, CHFN, Michelle Rickard DNP, APNP-C 2021 University of Tennessee Health Science Center

Adverse Childhood Experiences And Urinary Incontinence In Elementary School Aged Children, Amanda Jill Travis Msn, Fnp-C, Margaret C. Harvey Phd, Aprn, Acnp-Bc, Chfn, Michelle Rickard Dnp, Apnp-C

Doctor of Nursing Practice Projects

Purpose/Background: Adverse Childhood Experiences (ACEs) have an impact on health throughout the lifespan (Filletti et al., 1999; Hughes et al., 2017). These experiences range from physical and mental abuse, substance abuse in the home, parental separation or loss, financial instability, acute illness or injury, witnessing violence in the home or community, and incarceration of family members (Hughes et al., 2017). Understanding and screening for ACEs in children with urinary incontinence can help practitioners identify psychological stress as a potentially modifiable risk factor.

Methods: A 5-month chart review was performed identifying English speaking patients ages 6-11 years presenting to the outpatient …


Using Frap: A Mixed Method Geospatial Mapping And Rapid Qualitative Analysis Approach, To Uncover Barriers And Facilitators Of Diabetes Care In The Lehigh Valley., Autumn Kieber-Emmons MD, MPH, Kyle Shaak BS, Melanie B. Johnson MPA, Susan E. Hansen MA, Elaine Banerjee MD, MPH 2021 Lehigh Valley Health Network

Using Frap: A Mixed Method Geospatial Mapping And Rapid Qualitative Analysis Approach, To Uncover Barriers And Facilitators Of Diabetes Care In The Lehigh Valley., Autumn Kieber-Emmons Md, Mph, Kyle Shaak Bs, Melanie B. Johnson Mpa, Susan E. Hansen Ma, Elaine Banerjee Md, Mph

Department of Family Medicine

No abstract provided.


The Mediating/Moderating Role Of Cultural Context Factors On Self-Care Practices Among Those Living With Diabetes In Rural Appalachia, Brittany L. Smalls, Adebola Adegboyega, Ellen Combs, Matthew Rutledge, Philip M. Westgate, Md. Tofial Azam, Felipe De La Barra, Lovoria B. Williams, Nancy E. Schoenberg 2021 University of Kentucky

The Mediating/Moderating Role Of Cultural Context Factors On Self-Care Practices Among Those Living With Diabetes In Rural Appalachia, Brittany L. Smalls, Adebola Adegboyega, Ellen Combs, Matthew Rutledge, Philip M. Westgate, Md. Tofial Azam, Felipe De La Barra, Lovoria B. Williams, Nancy E. Schoenberg

Family and Community Medicine Faculty Publications

Background

The aim of this study was to examine whether cultural factors, such as religiosity and social support, mediate/moderate the relationship between personal/psychosocial factors and T2DM self-care in a rural Appalachian community.

Methods

Regression models were utilized to assess for mediation and moderation. Multilevel linear mixed effects models and GEE-type logistic regression models were fit for continuous (social support, self-care) and binary (religiosity) outcomes, respectively.

Results

The results indicated that cultural context factors (religiosity and social support) can mediate/moderate the relationship between psychosocial factors and T2DM self-care. Specifically, after adjusting for demographic variables, the findings suggested that social support may …


Down Syndrome And Dementia:: A Patient And Care-Giver Centered Approach, Mary M. Stephens, E. Adel Herge, Charmaine Wright 2021 Thomas Jefferson University

Down Syndrome And Dementia:: A Patient And Care-Giver Centered Approach, Mary M. Stephens, E. Adel Herge, Charmaine Wright

Department of Occupational Therapy Faculty Papers

No abstract provided.


Integrated Behavioral Health (Ibh) Program Updates And Evidence For Ibh In Sud, Rachelle Rene, PhD, BCB, HSMI 2021 Thomas Jefferson University

Integrated Behavioral Health (Ibh) Program Updates And Evidence For Ibh In Sud, Rachelle Rene, Phd, Bcb, Hsmi

Department of Family & Community Medicine Presentations and Grand Rounds

Learning Objectives

At the end of this presentation, the participant will be able to:

  1. Describe core components of the Primary Care Behavioral Health Model
  2. Identify IBH Program implementation highlights and challenges
  3. Discuss at least one intervention to address SUD in primary care


Genetic Analysis Of Archived Tumor Specimens For Hereditary Colorectal Cancer Syndromes In The Cajuns Of Louisiana, A Us Founder Population, Jordan J. Karlitz, Amanda Phillips, Kelly S. Sorrells, Shanti Rao 2021 Tulane University School of Medicine

Genetic Analysis Of Archived Tumor Specimens For Hereditary Colorectal Cancer Syndromes In The Cajuns Of Louisiana, A Us Founder Population, Jordan J. Karlitz, Amanda Phillips, Kelly S. Sorrells, Shanti Rao

School of Medicine Faculty Publications

INTRODUCTION: The Louisiana Acadian region (population 1.2 million), home of the Cajuns, has among the highest US colorectal cancer (CRC) rates. Although Cajuns are a known genetic founder population, studies assessing for hereditary CRC have not been performed. METHODS: A retrospective review of 2 hospital cancer registries was performed to identify young (<55) Cajun CRC patients in Lafayette, Louisiana (the Acadian region population center), diagnosed from 2003 to 2016. Men were studied because of the higher likelihoods of retaining Cajun surnames for ancestry identification compared with women. Immunohistochemistry for mismatch repair proteins associated with the Lynch syndrome (LS) was performed on tumors. Germline sequencing was performed on adjacent normal tissue of these archived formalin-fixed paraffin-embedded surgical resection specimens for pathogenic variants underlying CRC-associated syndromes, including LS, familial adenomatous polyposis, and others. RESULTS: Of 9 young Cajuns, a germline analysis revealed LS in 2 (MLH1 frameshift, MLH1 missense pathogenic variants). Both had immunohistochemistry-deficient MLH1. Two others had the same adenomatous polyposis coli variant of unknown significance (2 algorithms predicting deleterious and probably damaging change), making this a potential familial adenomatous polyposis founder effect candidate. DISCUSSION: This is the first study assessing for hereditary CRC in a large US regional founder population. This small study did not identify clear Cajun founder pathogenic variants. However, larger studies are warranted, which could also help clarify the clinical significance of the adenomatous polyposis coli variant of unknown significance. This study is important because it demonstrates that a retrospective tumor analysis can be used to ascertain the prevalence of genetic susceptibility in specific populations.


Management Of Recurrent Bacterial Vaginosis, Barbara Cymring, MD 2021 Thomas Jefferson University

Management Of Recurrent Bacterial Vaginosis, Barbara Cymring, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Objectives

  • Review the importance of appropriate management of recurrent BV (rBV)
  • Review the appropriate diagnosis of rBV
  • Review the causes and risk factors for BV and rBV
  • Review the current literature on treatment for rBV
  • Discuss some preventative measures for decreasing risk of BV infection


Teratogenic Medication Usage In Primary Care Of Women Of Reproductive Age, Krys Foster, MD, MPH, FAAFP 2021 Thomas Jefferson University

Teratogenic Medication Usage In Primary Care Of Women Of Reproductive Age, Krys Foster, Md, Mph, Faafp

Department of Family & Community Medicine Presentations and Grand Rounds

Introduction

  • Teratogenic medications are commonly prescribed to individuals with pregnancy potential
  • Despite knowledge of potential teratogenic effects, data suggest that effective communication regarding the risks and benefits of medication use in the context of the patient’s fertility goals remains inadequate
  • We will discuss recommendations for changes in education and healthcare delivery to facilitate thoughtful prescribing in this population

Learning Objectives

  • To review a common scenario faced by primary care physicians caring for individuals at risk of pregnancy
  • To recognize factors that might place certain patients at increased risk of teratogenic exposure in early pregnancy
  • To gain competence in assessing fertility …


A Qualitative Analysis Of Third-Year Medical Students' Reflection Essays Regarding The Impact Of Covid-19 On Their Education., Erin L. Kelly, Allison R. Casola, Kelsey Smith, Samantha Kelly, Maria Syl D. de la Cruz 2021 Thomas Jefferson University

A Qualitative Analysis Of Third-Year Medical Students' Reflection Essays Regarding The Impact Of Covid-19 On Their Education., Erin L. Kelly, Allison R. Casola, Kelsey Smith, Samantha Kelly, Maria Syl D. De La Cruz

Department of Family & Community Medicine Faculty Papers

BACKGROUND: The COVID-19 pandemic fundamentally changed every aspect of healthcare delivery and training. Few studies have reported on the impact of these changes on the experiences, skill development, and career expectations of medical students.

METHOD: Using 59 responses to a short reflection essay prompt, 3rd year medical students in Philadelphia described how the COVID-19 pandemic affected their education in mid-2020. Using conventional content analysis, six main themes were identified across 14 codes.

RESULTS: Students reported concerns regarding their decreased clinical skill training and specialty exposure on their career development due to the loss of in-person experience during their family medicine …


Osteoporosis, Susan Mockus Parks, MD 2021 Thomas Jefferson University

Osteoporosis, Susan Mockus Parks, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Objectives

Review importance of bone health

Define and identify osteopenia and osteoporosis

Learn treatment options for osteopenia

  • How to counsel patients
  • How to use FRAX calculator to assist with treatment decisions

Learn treatment options for osteoporosis

  • Become familiar with treatment guidelines and options


Residency Training On The Frontlines Of The Covid-19 Pandemic - A Qualitative Study From Tanzania, Mariam Noorani, Hussein Manji, Elizabeth Mmari, Samina Somji, Nahida Z. Walli, Sherin Kassamali, Shabbir Adamjee, Nancy Matillya, Hanifa Mbithe, Aliasger Nagri, Neelam Ismail 2021 Aga Khan University

Residency Training On The Frontlines Of The Covid-19 Pandemic - A Qualitative Study From Tanzania, Mariam Noorani, Hussein Manji, Elizabeth Mmari, Samina Somji, Nahida Z. Walli, Sherin Kassamali, Shabbir Adamjee, Nancy Matillya, Hanifa Mbithe, Aliasger Nagri, Neelam Ismail

Paediatrics and Child Health, East Africa

Introduction: the Coronavirus Disease 2019 pandemic has affected residency training globally. The aim of this study was to understand how the pandemic affected teaching and learning in residency programs in low resource settings where residents and faculty were working on the front line treating patients with the disease.

Methods: this qualitative study enrolled residents and faculty from the Aga Khan University in Tanzania who were providing front line care during the pandemic. Purposeful sampling was used and data was collected using focus group discussions and in-depth interviews between August and September 2020. Analysis was done using qualitative content analysis.

Results: …


An Approach To Faculty Development For Underrepresented Minorities In Medicine., Juan Robles, Tanya Anim, Maria Harsha Wusu, Krys E. Foster, Yury Parra, Octavia Amaechi, Kari-Claudia Allen, Jose E. Rodríguez, Kendall M. Campbell, Dmitry Tumin, Judy Washington 2021 Thomas Jefferson University

An Approach To Faculty Development For Underrepresented Minorities In Medicine., Juan Robles, Tanya Anim, Maria Harsha Wusu, Krys E. Foster, Yury Parra, Octavia Amaechi, Kari-Claudia Allen, Jose E. Rodríguez, Kendall M. Campbell, Dmitry Tumin, Judy Washington

Department of Family & Community Medicine Faculty Papers

OBJECTIVES: The diversity of the US physician workforce lags significantly behind the population, and the disparities in academic medicine are even greater, with underrepresented in medicine (URM) physicians accounting for only 6.8% of all US medical school faculty. We describe a "for URM by URM" pilot approach to faculty development for junior URM Family Medicine physicians that targets unique challenges faced by URM faculty.

METHODS: A year-long fellowship was created for junior URM academic clinician faculty with funding through the Society of Teachers of Family Medicine Project Fund. Seven junior faculty applied and were accepted to participate in the fellowship, …


Utilization Of Patient-Controlled Analgesia Reduces Length Of Stay Of Sickle Cell Crisis Hospitalizations, Brett M. Prestia, Talha Ramzan, Catherine Waldron, Ameer Malik, Robert M. Pallay, Candace R. Murbach, Mike Flynn, Eric Shaw PhD, Abdullah Kutlar, Daniel Lowe 2021 Memorial Health University Medical Center

Utilization Of Patient-Controlled Analgesia Reduces Length Of Stay Of Sickle Cell Crisis Hospitalizations, Brett M. Prestia, Talha Ramzan, Catherine Waldron, Ameer Malik, Robert M. Pallay, Candace R. Murbach, Mike Flynn, Eric Shaw Phd, Abdullah Kutlar, Daniel Lowe

HCA Healthcare Journal of Medicine

Background

Sickle cell crisis hospitalizations are emotionally and financially burdensome to patients and healthcare systems, and processes to decrease the frequency or length of stay of these crises should be examined.

Methods

This is a multicenter retrospective hospital record review of sickle cell crisis hospitalizations as defined by ICD-10 codes (D57.1-4), from January 2016 through December 2019, examining inpatient medication administration records and length of stay among admitted adults aged 18–65 years. Patient controlled analgesia orders using morphine, hydromorphone, fentanyl and/or merperidine at any point of an admission (n=188) were compared to admissions without any patient-controlled analgesia orders (n=2,159). The …


Use Of Ultrasound-Guided Platelet-Rich Plasma In The Treatment Of Carpometacarpal Osteoarthritis, Manuel Britto, Siraaj Dawood, Siyang Lu, Martin Canillas 2021 Oak Hill Hospital

Use Of Ultrasound-Guided Platelet-Rich Plasma In The Treatment Of Carpometacarpal Osteoarthritis, Manuel Britto, Siraaj Dawood, Siyang Lu, Martin Canillas

HCA Healthcare Journal of Medicine

Introduction

Osteoarthritis (OA) is the most common form of arthritis and can severely affect function and quality of life. Platelet-rich plasma (PRP) is derived from a patient’s own blood and has potential as an adjunct to treat OA. However, research has been limited for small joints such as the carpometacarpal (CMC) joint.

Clinical Findings

A 65-year-old Caucasian male complained of bilateral wrist and neck pain after a motor vehicle accident. His initial exam noted swelling, tenderness and pain with movement at the bilateral thumb CMC joints and anatomic snuffboxes. However, there was no strength, range of motion or tactile deficits …


Management And Diagnosis Of Hypothyroidism, Catherine Guariglia, MD 2021 Thomas Jefferson University

Management And Diagnosis Of Hypothyroidism, Catherine Guariglia, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Goals

  • Recognize the different etiologies of hypothyroidism
  • Identify signs and symptoms of hypothyroidism
  • Feel comfortable diagnosing and treating primary hypothyroidism
  • Define subclinical hypothyroidism and when/if it is necessary to treat
  • Recognize how pregnancy influences hypothyroidism management
  • Be able to counsel patients on treatment for hypothyroidism


There Is Insufficient Evidence To Recommend Bremelanotide For Hypoactive Sexual Desire Disorder, Scott Yaekle MD, Halima Ali MD, Carol Baker MD 2021 Beaumont Wayne Hospital Family Medicine Residency Program

There Is Insufficient Evidence To Recommend Bremelanotide For Hypoactive Sexual Desire Disorder, Scott Yaekle Md, Halima Ali Md, Carol Baker Md

Clinical Research in Practice: The Journal of Team Hippocrates

An informed consent discussion for a patient with Hypoactive Sexual Desire Disorder.


Heart Failure Transitions Of Care Program, Samantha Macko, PharmD 2021 Thomas Jefferson University

Heart Failure Transitions Of Care Program, Samantha Macko, Pharmd

Department of Family & Community Medicine Presentations and Grand Rounds

Objectives

  • Heart failure overview; statistics, risk factors, signs and symptoms
  • List heart failure therapeutic treatment options
  • Explain importance of continuation of care for heart failure patients after initial hospital discharge
  • Discuss importance of multidisciplinary approach to treatment of heart failure (HF) patients
  • Discuss components of heart failure transitions of care (HFTOC) program at Thomas Jefferson University Hospital


Adhd In Adolescents And Adults, Hannah Facey, MD 2021 Thomas Jefferson University

Adhd In Adolescents And Adults, Hannah Facey, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Objectives

  • Understand the concept of neurodiversity
  • Define ADHD
  • Review the diagnostic criteria and challenges with diagnosis for ADHD in adults
  • Explore our role as family medicine physicians in diagnosis and treatment
  • Discover the prevalence of comorbid conditions associated with ADHD
  • Obtain a general understanding of the categories of medical treatments available for adults with ADHD
  • Gain a deeper appreciation for the role that biases play in the under- and misdiagnosis of women and BIPOC


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