Bulbar-Predominant Presentation Of Myasthenia Gravis: Poster Presentation, 2023 HCA Healthcare
Bulbar-Predominant Presentation Of Myasthenia Gravis: Poster Presentation, Duncan Mckinney, Rumana Khan, Edward Griffin
Capital Division Research Day 2023
No abstract provided.
Case Based Review On Headaches And Cerebral Venous Thromboembolism Post Covid-19 Infection, 2023 HCA Healthcare
Case Based Review On Headaches And Cerebral Venous Thromboembolism Post Covid-19 Infection, Aishwarya Raich, Tanvir Khosla, Vishnu Halthore, Ali Abu-Alya, Venkatachalam Veerappan
Far West Division Research Day 2023
No abstract provided.
Time Is Brain: Improving Door To Iv Tpa Time In Emergency Department, 2023 HCA Healthcare
Time Is Brain: Improving Door To Iv Tpa Time In Emergency Department, Habiba Khan, Dallin Ollerton, George Matus, Ramesh Komaragiri
Central & West Texas Research Day 2023
No abstract provided.
Diagnostic Considerations Of Giant Cell Arteritis In Veterans, 2023 HCA Healthcare
Diagnostic Considerations Of Giant Cell Arteritis In Veterans, Paul Kay, Molly Phan, Kimberly M. Winges
East Florida Research Day 2023
Please see supplemental content for full abstract with references.
Introduction: Giant cell arteritis (GCA) is the most common primary systemic vasculitis in adults, but studies to date have been limited in volume or subject to retrospective meta-analysis.1 The United States Veterans Health Administration (VHA) holds the nation’s largest electronic medical database. Veterans comprise 7% of the American population, including 24% of the population over 75 years old.2 Building upon a clinical study of one VHA site cohort,3 we used this database to identify differences in demographics, risk factors, associated systemic conditions, and biopsy yield within the entire veteran population using …
Moyamoya Disease: Classic Imaging With Atypical Presentation, 2023 HCA Healthcare
Moyamoya Disease: Classic Imaging With Atypical Presentation, Amanda Fahrenbruck, Holly Fleming, Elena Salikhova-Neace, Dmitriy Scherbak
Continental, MidAmerica, & Mountain Divisions Research Day 2023
No abstract provided.
Late Onset Sheehan Syndrome 23 Years After Post-Partum Hemorrhage, 2023 HCA Healthcare
Late Onset Sheehan Syndrome 23 Years After Post-Partum Hemorrhage, Igbayilola Dosunmu, Ali Tariq Alvi, Sarah Kaufman, Ayesha Malik
East Florida Research Day 2023
Please see supplemental content for full abstract with figures and references.
Sheehan syndrome is defined as ischemic necrosis of pituitary gland following massive postpartum hemorrhage leading to panhypopituitarism. It has an insidious course with multitude of presentations. The majority of cases remain undiagnosed for many years after the delivery with average time following postpartum hemorrhage to diagnosis of Sheehan syndrome is believed to be almost 13 years according to one study. Here, we present a unique case of late onset of Sheehan syndrome 23 years after the last childbirth which was complicated by hemorrhage. To our knowledge, this is the …
Fever Of Unknown Origin Secondary To Staphylococcus Epidermidis Infective Endocarditis In A Patient With Aicardi Syndrome, 2023 HCA Healthcare
Fever Of Unknown Origin Secondary To Staphylococcus Epidermidis Infective Endocarditis In A Patient With Aicardi Syndrome, Kimberly Sanchez Lopez, Elvis Caraballo Antonio, Gabriel Barciela Perez, Melanio J. Rodriguez, Yeissen Godinez
East Florida Research Day 2023
INTRODUCTION Aicardi syndrome is a rare neurodevelopmental disorder predominantly affecting females and characterized by agenesis of the corpus callosum, infantile spasms, and distinctive chorioretinal lacunae. We present the case of a 24-year-old female with a known history of Aicardi syndrome who presented with fever of unknown origin, ultimately attributed to Staphylococcus Epidermidis infective endocarditis involving a native valve.
CASE DESCRIPTION A 24-year-old female with a history significant for Aicardi syndrome and epilepsy presented to the emergency department for fever during the past week; her primary care physician sent her for outpatient blood work a few days prior, including blood culture, …
Risk Factors For Depression Progression In Parkinson's Disease: A Retrospective Cohort Study, 2023 HCA Healthcare
Risk Factors For Depression Progression In Parkinson's Disease: A Retrospective Cohort Study, David Kosoy, James Cassuto, Gregory Kurgansky
East Florida Research Day 2023
Introduction: Depression is a common non-motor symptom in Parkinson's disease (PD) with a significant impact on quality of life and overall prognosis. Despite the availability of effective treatments, many PD patients with depression do not receive timely diagnosis and appropriate intervention. This study aimed to identify risk factors for depression progression in PD to inform clinical practice and future research.
Methods: We conducted a retrospective cohort study of PD patients using registry data from the Parkinson's Progression Markers Initiative (PPMI) dataset. The primary outcome was depression progression, defined as a 2-point or greater increase in the MDS-UPRDS depression score within …
Posterior Reversible Encephalopathy Syndrome: A Case Of Elevated Blood Pressure And New Seizure Onset Post Nephrectomy, 2023 HCA Healthcare
Posterior Reversible Encephalopathy Syndrome: A Case Of Elevated Blood Pressure And New Seizure Onset Post Nephrectomy, Jessica Bautista, Kyle Adkins, Lisa Gieseke
Continental, MidAmerica, & Mountain Divisions Research Day 2023
No abstract provided.
Neurolupus In A Previously Healthy Young Caucasian Male, 2023 HCA Healthcare
Neurolupus In A Previously Healthy Young Caucasian Male, Kavanya Feustel, Joshua Ralston, Kelly Schulte, Jeffrey Ramsey, Deren Goker, Jacob Keeling, Dmitriy Scherbak
Continental, MidAmerica, & Mountain Divisions Research Day 2023
No abstract provided.
Extra-Axial Desmoplastic/Nodular Medulloblastoma, Shh-Activated In Adult: A Case Report, 2023 HCA Healthcare
Extra-Axial Desmoplastic/Nodular Medulloblastoma, Shh-Activated In Adult: A Case Report, Gul Wymer, Fatemeh Mousavi, Jennifer Barker
East Florida Research Day 2023
Introduction: Medulloblastoma (MB) is an embryonal central nervous system (CNS) tumor located in the posterior cranial fossa. Medulloblastoma is one of the most common malignant pediatric brain tumors, accounts for 25% of all pediatric intracranial tumors, but rare in adults; and constitute 0.4%-1% of adult primary brain tumors. The incidence of medulloblastomas in adults is approximately 0.5 per million per year and decreases with age with male predominance. Medulloblastomas classically appear as well-defined masses in the cerebellum that enhance both computed tomography (CT) of the head and brain magnetic resonance imaging (MRI) with gadolinium contrast. The clinical symptoms and signs …
The Treatment Of Depression In Alzheimer's Disease Using Neuromodulation: A Literature Review, 2023 HCA Healthcare
The Treatment Of Depression In Alzheimer's Disease Using Neuromodulation: A Literature Review, Aaron Marbn, Shane Ragland, Thalia Adrian, Clara Alvarez Villalba, Samuel Neuhut
East Florida Research Day 2023
Please see supplemental content for full abstract with references.
INTRODUCTION: An estimated 44 million individuals live with Alzheimer's Dementia globally, a number expected to triple by 2050.1 Depression is a commonly observed comorbidity in individuals with Alzheimer's disease. Traditional antidepressant medications often pose challenges due to their side effects and limited efficacy in this population. As a result, alternative therapeutic approaches are being explored, with Transcranial Magnetic Stimulation (TMS) emerging as a promising intervention for treating depression in Alzheimer's patients. TMS is a non-invasive brain stimulation technique that utilizes magnetic fields to modulate neural activity in targeted brain regions …
The Effect Of Early Palliative Care Consultation For Patient With Traumatic Brain Injury On Procedure Utilization, Length Of Stay And Discharge Location, 2023 HCA Healthcare
The Effect Of Early Palliative Care Consultation For Patient With Traumatic Brain Injury On Procedure Utilization, Length Of Stay And Discharge Location, Abdulelah Almutairi, Donald Courtney, Heather Rhodes
South Atlantic Division Research Day 2023
No abstract provided.
Thoracic Radiculopathy Following Permanent Spinal Cord Stimulator Placement, 2023 HCA Healthcare
Thoracic Radiculopathy Following Permanent Spinal Cord Stimulator Placement, Nicholas Gentry, Desiree Aird, Farayi Mbuvah
South Atlantic Division Research Day 2023
No abstract provided.
Incidence Of Adult (>40y) Traumatic Brain Injury And Likelihood Of Routine Discharge: Do Co-Morbidities Matter?, 2023 HCA Healthcare
Incidence Of Adult (>40y) Traumatic Brain Injury And Likelihood Of Routine Discharge: Do Co-Morbidities Matter?, Yelena Pecheny, Heather Rhodes, Stephanie Anderson, Antonio Pepe, Donald Courtney
South Atlantic Division Research Day 2023
No abstract provided.
Tea, Toast, And Strokes, 2023 HCA Healthcare
Tea, Toast, And Strokes, Mark Azmy, Jennifer Broyles, Sean Quinonez, Admir Seferovic
West Florida Division Research Day 2023
No abstract provided.
Wernicke Encephalopathy: Interplay Between Magnesium And Thiamine, 2023 HCA Healthcare
Wernicke Encephalopathy: Interplay Between Magnesium And Thiamine, Richard Allen Gorman Ii, Mark Stine, Rafael Vaello, Patrick J. Stocker
West Florida Division Research Day 2023
No abstract provided.
Characterizing The Function Of B Cells That Accumulate In The Inflamed Central Nervous System In Anti-Myelin Autoimmunity, 2022 The University of Western Ontario
Characterizing The Function Of B Cells That Accumulate In The Inflamed Central Nervous System In Anti-Myelin Autoimmunity, Lika Chowdhury
Electronic Thesis and Dissertation Repository
While the role of autoimmune T cells has been extensively studied in anti-myelin
autoimmunity, little is known about the function of B cells in multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system (CNS). B cells form clusters with T cells in the meninges directly adjacent to demyelinating lesions. Previous studies have shown that disease progression is dependent on the depletion of specific populations of B cells, but it is not clear which contributes to pathology or how. The purpose of this thesis is to characterize the population of meningeal B cells to determine how they differ …
How To Manage The Initiation Of Apomorphine Therapy Without Antiemetic Pretreatment: A Review Of The Literature, 2022 Parkinson's Disease and Movement Disorders Center of Boca Raton
How To Manage The Initiation Of Apomorphine Therapy Without Antiemetic Pretreatment: A Review Of The Literature, Stuart H. Isaacson, Richard B. Dewey, Rajesh Pahwa, Daniel E. Kremens
Department of Neurology Faculty Papers
Introduction
Pretreatment with the antiemetic trimethobenzamide has been recommended practice in the United States (US) to address the risk of nausea and vomiting during initiation of apomorphine treatment. However, trimethobenzamide is no longer being manufactured in the US, and despite the recent update to the US prescribing information, there may be uncertainty regarding how to initiate apomorphine.
Methods
To better understand why antiemetic pretreatment was recommended and if it is necessary when initiating apomorphine therapy, we performed a literature review of subcutaneous apomorphine therapy initiation with and without antiemetic pretreatment in patients with PD.
Results
Three studies were identified as …
Med12 Is A Critical Regulator Of Neural Crest Lineage And Nervous System Myelination, 2022 The Texas Medical Center Library
Med12 Is A Critical Regulator Of Neural Crest Lineage And Nervous System Myelination, Fatma Betul Aksoy Yasar
Dissertations & Theses (Open Access)
The Mediator complex (MED) is a multi-subunit protein complex integral to the eukaryotic transcription machinery. MED12 is a Cdk8- regulatory kinase module subunit directly implicated in human disease and is genetically altered in neurological disease and cancer. Numerous attempts at generating an in vivo system to study the role of Med12 failed due to embryonic lethality associated with germline or developmental disruption of Med12 gene. To understand the cellular and molecular processes associated with its role in disease, we generated multiple mouse models with targeted depletion of MED12 in distinct cellular lineages. Our genetically engineered models with induced and conditional …