Female Urogenital Diseases and Pregnancy Complications Commons^™

Changing The World With One Cell: The Story Of Hela, Allison Roberts

Allison Roberts

Poster Created for the Diversity Committee Fall 2011 Culture Corner featuring The Immortal Life of Henrietta Lacks. Henrietta Lacks’ cell culture spawned changes in medicine, science, ethics, society and the world. This Semester’s Culture Corner features selections from UT Libraries collection that highlight the areas effected by this one human and her immortal cell.

Use Of Mobile Telemedicine For Cervical Cancer Screening, Kelly E. Quinley, Rachel H. Gormley, Sarah Ratcliffe, Ting Shih, Zsofia Szep, Ann Steiner, Doreen Ramogola-Masire, Carrie Kovarik

Botswana-UPenn Scholarly Publications

Visual inspection of the cervix with application of 4% acetic acid (VIA) is an inexpensive alternative to cytology-based screening in areas where resources are limited, such as in many developing countries. We have examined the diagnostic agreement between off-site (remote) expert diagnosis using photographs of the cervix (photographic inspection with acetic acid, PIA) and in-person VIA. The images for remote evaluation were taken with a mobile phone and transmitted by MMS. The study population consisted of 95 HIV-positive women in Gaborone, Botswana. An expert gynaecologist made a definitive positive or negative reading on the PIA results of 64 out of …

To Consult Or Not To Consult? Investigating Barriers To Dysparenia Treatment-Seeking In Young Women, Robyn L. Donaldson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Little is known about mediators of treatment-seeking in dyspareunia. The general health belief literature as well as some existing qualitative data specific to dyspareunia, however, suggests a number of potentially significant barriers that may delay or prevent women from enlisting the aid of health care professionals. The aim of this study was to investigate influences on dyspareunia treatment-seeking behavior in young women, for whom the consequences of treatment avoidance are hypothesized to be the greatest. Given the lack of standardized health behavior measures relevant to intercourse pain, we constructed a measure assessing potential barriers to dyspareunia treatment-seeking. An exploratory principal …

High-Risk Human Papillomavirus (Hpv): An Emerging Health Issue For Women And Minorities, Dierdre O. Turner

UNLV Theses, Dissertations, Professional Papers, and Capstones

The human papillomavirus (HPV) is the cause of nearly all cases of cervical cancers worldwide. HPV viral DNA is found in more than 99% of cervical cancers. In addition to cervical cancer, HPV is also associated with some breast and oral cancers. White women have been showing a decline in breast cancer rates while black women are continuously showing higher rates of mortality from both breast and cervical cancer. Minority women are also more likely to receive a late diagnosis and are showing increased incidence of oral cancer, which makes study of HPV in women and minorities significant.

To date, …

Characterization Of The Sigma Factor Proteins And The Dna Binding Protein Euo Of Chlamydia, Cory L. Blackwell

Theses and Dissertations (ETD)

Chlamydia spp. are prokaryotic obligate intracellular pathogens with a unique, biphasic developmental cycle in which an infectious, extracellular form termed the elementary body (EB) interconverts with a metabolically active intracellular reticulate body (RB) within host cells. Subsets of genes are differentially expressed during the developmental cycle, and these genes are believed to be responsible for the transitions between the EB and RB forms. The goal of these studies was to explore two potential mechanisms that may function in regulating developmental cycle stage‑specific gene expression in chlamydiae: a cascade of sigma factor expression and the binding of the early stage protein …

Socioeconomic Status And Polycystic Ovary Syndrome, Sharon Stein Merkin, Ricardo Azziz, Teresa E. Seeman, Ronit Calderon-Margalit, Martha L. Daviglus, Catarina I. Kiefe, Karen A. Matthews, Barbara Sternfeld, David S. Siscovick

Catarina I. Kiefe

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common metabolic-endocrine disorder in women and is associated with a number of metabolic morbidities. We examined the association of PCOS and its components with socioeconomic status (SES) over the life course to explore the role of the environment on the development of PCOS.

METHODS: Participants included 1163 women, aged 34-39, from the Coronary Artery Risk Development in Young Adults (CARDIA) Women's Study, examined at year 16 of the CARDIA study (2001). PCOS was defined according to the 1990 National Institutes of Health (NIH) criteria.

RESULTS: Logistic regression models, adjusted for age, body mass …

Management And Outcomes Of Renal Disease And Acute Myocardial Infarction, Paul Santolucito, Dennis Tighe, David Mcmanus, Jorge Yarzebski, Darleen Lessard, Joel Gore, Robert Goldberg

Jorge L. Yarzebski

BACKGROUND: Contemporary trends in the management and outcomes of chronic kidney disease patients who develop an acute myocardial infarction have not been adequately described, particularly from the more generalizable perspective of a population-based investigation. METHODS: The study population consisted of 6219 residents of the Worcester, Massachusetts, metropolitan area who were hospitalized with acute myocardial infarction in 6 annual periods between 1995 and 2005. Patients were categorized as having preserved kidney function (n=3154), mild to moderate chronic kidney disease (n=2313), or severe chronic kidney disease (n=752) at the time of hospital admission. RESULTS: Patients with chronic kidney disease were more likely …

Does Tranexamic Acid Effectively And Safely Reduce Menstrual Blood Loss (Mbl) In Women With Menorrhagia Or Iud Induced Mbl?, Veronica W. Chang

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: To determine if Tranexamic Acid effectively and safely reduce menstrual blood loss (MBL) in women with Menorrhagia or IUD induced MBL?

Why Doesn’T A Pregnant Woman Reject Her Fetus, Lisa Merry

3690: A Journal of First-Year Student Research Writing

Overview: Recurrent Pregnancy loss (RPL) occurs when a woman has three or more consecutive miscarriages; this phenomenon happens in about 1-3% of women. Why some women reject their unborn fetus and others carry theirs to term is still unclear. There are four main theories that exist regarding why some women reject their fetus and others do not: the maternal immune system might not be capable of responding to fetal antigens due to mechanisms that induce tolerance in responding maternal cells; a “barrier” may from between mother and fetus, preventing access of maternal immune cell to fetal antigens; fetal cells may …

Use Of Do-Not-Resuscitate Orders In Patients With Kidney Disease Hospitalized With Acute Myocardial Infarction, Joline Chen, Jonathan Sosnov, Darleen Lessard, Jorge Yarzebski, Joel Gore, Robert Goldberg

Jorge L. Yarzebski

BACKGROUND: Patients with kidney disease are at increased risk for adverse health outcomes in comparison to patients without kidney disease. Therefore, patients with kidney disease may have greater use of do-not-resuscitate (DNR) orders than patients without kidney disease in the setting of an acute illness. We examined the association between advanced kidney disease and use of DNR orders in patients admitted with an acute myocardial infarction (AMI) to all greater Worcester, MA, hospitals as part of an epidemiological study.

METHODS: Use of DNR orders in 4,033 Worcester residents hospitalized with AMI at 11 greater Worcester medical centers during 1997, 1999, …

Recurrent Urinary Tract Infections In Females, Raheela Mohsin Rizvi, Khurram Mutahir Siddiqui

Department of Obstetrics & Gynaecology

Uncomplicated Urinary tract infections are common in adult women across the entire age spectrum, with mean annual incidence of 15% and 10% in those aged 15-39 and 40-79 years, respectively. Urinary tract infection (UTI), with its diverse clinical syndromes and affected host groups, remains one of the most common but widejly misunderstood and challenging infectious diseases encountered in clinical practice. Recurrent urinary tract infections (UTIs) present a significant problem for women and a challenge for the doctors who care for them. The diagnosis of uncomplicated UTI can be achieved best by a thorough assessment of patient symptoms with or without …