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Endocrine System Diseases Commons

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Basic Diabetes Class Handout Without Goals - English, Michele Spatz, Ruth Dallas 2018 Pacific University

Basic Diabetes Class Handout Without Goals - English, Michele Spatz, Ruth Dallas

Diabetes Education Tools

This diabetic patient handout reviews A1C test results and simply illustrates what the patient can do to stay healthy.


Insulin Instructions - English, Michele Spatz, Ruth Dallas 2018 Pacific University

Insulin Instructions - English, Michele Spatz, Ruth Dallas

Diabetes Education Tools

A one-page handout for diabetic patients explaining how to administer their insulin and safely store it.


What About Alcohol And Diabetes? - English, Michele Spatz, Ruth Dallas 2018 Pacific University

What About Alcohol And Diabetes? - English, Michele Spatz, Ruth Dallas

Diabetes Education Tools

This one page handout discusses the effects of drinking alcohol on diabetes.


Blood Glucose Goals - English, Michele Spatz, Ruth Dallas 2018 Pacific University

Blood Glucose Goals - English, Michele Spatz, Ruth Dallas

Diabetes Education Tools

Simple, one page handout illustrating blood glucose goals.


What About Alcohol And Diabetes? - Spanish, Michele Spatz, Ruth Dallas 2018 Pacific University

What About Alcohol And Diabetes? - Spanish, Michele Spatz, Ruth Dallas

Diabetes Education Tools

One page handout discusses the effects of drinking alcohol on diabetes. (Spanish)


Foot Care - Spanish, Michele Spatz, Ruth Dallas 2018 Pacific University

Foot Care - Spanish, Michele Spatz, Ruth Dallas

Diabetes Education Tools

A simple, illustrated handout explaining foot care for diabetes patients. (Spanish)


Foot Care - English, Michele Spatz, Ruth Dallas 2018 Pacific University

Foot Care - English, Michele Spatz, Ruth Dallas

Diabetes Education Tools

A simple, illustrated handout explaining foot care for diabetes patients.


Food Label - Spanish, Michele Spatz, Ruth Dallas 2018 Pacific University

Food Label - Spanish, Michele Spatz, Ruth Dallas

Diabetes Education Tools

Illustrated food label for diabetics to explain how to identify total carbohydrates. (Spanish)


Blood Glucose Log 4x/Day With Carbs, Snacks And Insulin - Spanish, Michele Spatz, Ruth Dallas 2018 Pacific University

Blood Glucose Log 4x/Day With Carbs, Snacks And Insulin - Spanish, Michele Spatz, Ruth Dallas

Diabetes Education Tools

A log for a patient to record 4 times/day his/her blood glucose levels, carbohydrates and snacks consumed and their insulin amounts. (Spanish)


Blood Glucose Log 4x/Day With Carbs, Snacks And Insulin - English, Michele Spatz, Ruth Dallas 2018 Pacific University

Blood Glucose Log 4x/Day With Carbs, Snacks And Insulin - English, Michele Spatz, Ruth Dallas

Diabetes Education Tools

A log for a patient to record 4 times/day his/her blood glucose levels, carbohydrates and snacks consumed and their insulin amounts.


Cost-Effectiveness Analysis Of Metformin+Dipeptidyl Peptidase-4 Inhibitors Compared To Metformin+Sulfonylureas For Treatment Of Type 2 Diabetes, Christina S. Kwon, Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio 2018 MCPHS University

Cost-Effectiveness Analysis Of Metformin+Dipeptidyl Peptidase-4 Inhibitors Compared To Metformin+Sulfonylureas For Treatment Of Type 2 Diabetes, Christina S. Kwon, Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio

Pharmacy Faculty Articles and Research

Background: Patients with type 2 diabetes (T2D) typically use several drug treatments during their lifetime. There is a debate about the best second-line therapy after metformin monotherapy failure due to the increasing number of available antidiabetic drugs and the lack of comparative clinical trials of secondary treatment regimens. While prior research compared the cost-effectiveness of two alternative drugs, the literature assessing T2D treatment pathways is scarce. The purpose of this study was to evaluate the long-term cost-effectiveness of dipeptidyl peptidase-4 inhibitors (DPP-4i) compared to sulfonylureas (SU) as second-line therapy in combination with metformin in patients with T2D.

Methods: A Markov ...


Diabetes Impairs Wound Healing By Dnmt1-Dependent Dysregulation Of Hematopoietic Stem Cells Differentiation Towards Macrophages, Jinglian Yan, Guodong Tie, Shoying Wang, Amanda A. Tutto, Natale DeMarco, Lyne Khair, Thomas G. Fazzio, Louis M. Messina 2018 University of Massachusetts Medical School

Diabetes Impairs Wound Healing By Dnmt1-Dependent Dysregulation Of Hematopoietic Stem Cells Differentiation Towards Macrophages, Jinglian Yan, Guodong Tie, Shoying Wang, Amanda A. Tutto, Natale Demarco, Lyne Khair, Thomas G. Fazzio, Louis M. Messina

Open Access Articles

People with type 2 diabetes mellitus (T2DM) have a 25-fold higher risk of limb loss than non-diabetics due in large part to impaired wound healing. Here, we show that the impaired wound healing phenotype found in T2D mice is recapitulated in lethally irradiated wild type recipients, whose hematopoiesis is reconstituted with hematopoietic stem cells (HSCs) from T2D mice, indicating an HSC-autonomous mechanism. This impaired wound healing phenotype of T2D mice is due to a Nox-2-dependent increase in HSC oxidant stress that decreases microRNA let-7d-3p, which, in turn, directly upregulates Dnmt1, leading to the hypermethylation of Notch1, PU.1, and Klf4 ...


Gene Regulation In The Hypothalamic-Pituitary-Gonadal Axis Of The Green Anole Lizard (Anolis Carolinensis)., Joshua N. Peters 2018 Minnesota State University, Mankato

Gene Regulation In The Hypothalamic-Pituitary-Gonadal Axis Of The Green Anole Lizard (Anolis Carolinensis)., Joshua N. Peters

All Theses, Dissertations, and Other Capstone Projects

Studies examining the hypothalamic-pituitary-gonad axis (HPG) in Anolis carolinensis provide insight into the regulation of this axis under extremely different reproductive conditions. Molecular studies indicate that kisspeptin proteins, transcribed from kiss1 and kiss2 genes, are produced in the hypothalamus where they bind G protein-coupled receptor 54 (GPR54), activating the HPG axis. Gonadotropin inhibitory hormone (GnIH) and its receptors, G protein-coupled receptor 147 and 74 (GPR147 and GPR74), down regulate HPG axis function. In this experiment we examined HPG axis gene expression in the green anole lizard (Anolis carolinensis), a seasonally breeding species with higher steroid hormone levels in the breeding ...


Comparing Prevalence Of Medication-Related Osteonecrosis Of The Jaw (Mronj) Due To Denosumab And Bisphosphonates As A Side Effect Of Osteoporosis Treatment, Kendra Apland 2018 University of North Dakota

Comparing Prevalence Of Medication-Related Osteonecrosis Of The Jaw (Mronj) Due To Denosumab And Bisphosphonates As A Side Effect Of Osteoporosis Treatment, Kendra Apland

Physician Assistant Scholarly Project Posters

As the baby boomer generation continues to age, the diagnosis of osteoporosis and its side effects will continue to increase. Denosumab and bisphosphonates (BPs) are some of the most common medication classes used to treat osteopenia and osteoporosis, but it is believed that both medications have the possible side effect of medication-related osteonecrosis of the jaw (MRONJ). The purpose of this paper is to uncover if MRONJ is a side effect of osteoporosis treatment and which medication carries the highest incidence rate. Through a review of several electronic databases and several peer reviewed research articles, a wide range of reported ...


Comparing The Effectiveness Of A Low Carbohydrate Diet And Metformin On Glycosylated Hemoglobin Reduction In Type Two Diabetes Mellitus, Ashley Schultz 2018 University of North Dakota

Comparing The Effectiveness Of A Low Carbohydrate Diet And Metformin On Glycosylated Hemoglobin Reduction In Type Two Diabetes Mellitus, Ashley Schultz

Physician Assistant Scholarly Project Papers

In this study, a low carbohydrate diet and metformin pharmacotherapy were compared to determine their effect on HbA1c in the type two diabetic patient. Several high quality studies were examined along with each treatment's effect on mainly HbA1c, but also other parameters such as body weight, cholesterol, and fasting and post prandial blood glucose levels. The study showed that both the low carbohydrate diet and metformin pharmacotherapy were effective at lowering HbA1c in the type two diabetic patient. The low carbohydrate diet showed a 0.2% increase in HbA1c all the way to a 2.2% decrease in baseline ...


Letrozole Vs. Clomiphene Citrate For Infertility In Polycystic Ovarian Syndrome, Kailey Potratz 2018 University of North Dakota

Letrozole Vs. Clomiphene Citrate For Infertility In Polycystic Ovarian Syndrome, Kailey Potratz

Physician Assistant Scholarly Project Posters

Purpose

To determine if letrozole is an equal or better alternative to clomiphene citrate for infertility treatment in PCOS patients.

Literature Review

Letrozole was found to have higher ovulation rates, fewer twin pregnancies/more single births, higher pregnancy rates, and higher live birth rates compared to clomiphene citrate. There were conflicting results for endometrial thickness and single follicle stimulation. Neither letrozole or clomiphene citrate was superior to the other for ovarian hyperstimulation syndrome. There were no significant differences between letrozole and clomiphene citrate regarding congenital abnormalities and miscarriage rates. The results regarding ectopic pregnancies were comparable between both groups.

Conclusion ...


Comparing The Effectiveness Of A Low Carbohydrate Diet And Metformin On Glycosylated Hemoglobin Reduction In Type Two Diabetes Mellitus, Ashley Schultz 2018 University of North Dakota

Comparing The Effectiveness Of A Low Carbohydrate Diet And Metformin On Glycosylated Hemoglobin Reduction In Type Two Diabetes Mellitus, Ashley Schultz

Physician Assistant Scholarly Project Posters

In this study, a low carbohydrate diet and metformin pharmacotherapy were compared to determine their effect on HbA1c in the type two diabetic patient. Several high quality studies were examined along with each treatment's effect on mainly HbA1c, but also other parameters such as body weight, cholesterol, and fasting and post prandial blood glucose levels. The study showed that both the low carbohydrate diet and metformin pharmacotherapy were effective at lowering HbA1c in the type two diabetic patient. The low carbohydrate diet showed a 0.2% increase in HbA1c all the way to a 2.2% decrease in baseline ...


Seychelles: Diabetes, Camille Myers 2018 Augustana College, Rock Island Illinois

Seychelles: Diabetes, Camille Myers

Global Public Health

One of the major health problems in Seychelles, a cluster of islands off the coast of Eastern Africa, is diabetes. There are many different types of diabetes, but the most common type to this region is Type 2 diabetes. At this time Seychelles, and many other countries in Africa, have about half of the adult population diagnosed with Type 2 diabetes. Along with the diagnosis of diabetes being a problem, people in Seychelles often go undiagnosed for a while because they are ignorant to the risks and the symptoms of the disease. Only about 50% of the population with pre-diabetic ...


Qatar: Diabetes, DiAngelo Gonzalez 2018 Augustana College, Rock Island Illinois

Qatar: Diabetes, Diangelo Gonzalez

Global Public Health

The State of Qatar is a developed nation that is located in the Middle East and borders the Persian Gulf and Saudi Arabia. The nation is a constitutional monarchy and is currently led by Amir Tamim bin Hamad Al Thani. The 2,300,000+ people of Qatar face many major challenges. Although it is one of the wealthiest nations in the Middle East, Qatar faces issues of human trafficking, migrants willing to work in poor conditions, and Middle Eastern Respiratory Syndrome (MERS). The most critical issue that plagues this county is diabetes, both I and II. Diabetes is a disease ...


Comparing Prevalence Of Medication-Related Osteonecrosis Of The Jaw (Mronj) Due To Denosumab And Bisphosphonates As A Side Effect Of Osteoporosis Treatment, Kendra Apland 2018 University of North Dakota

Comparing Prevalence Of Medication-Related Osteonecrosis Of The Jaw (Mronj) Due To Denosumab And Bisphosphonates As A Side Effect Of Osteoporosis Treatment, Kendra Apland

Physician Assistant Scholarly Project Papers

As the baby boomer generation continues to age, the diagnosis of osteoporosis and its side effects will continue to increase. Denosumab and bisphosphonates (BPs) are some of the most common medication classes used to treat osteopenia and osteoporosis, but it is believed that both medications have the possible side effect of medication-related osteonecrosis of the jaw (MRONJ). The purpose of this paper is to uncover if MRONJ is a side effect of osteoporosis treatment and which medication carries the highest incidence rate. Through a review of several electronic databases and several peer reviewed research articles, a wide range of reported ...


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