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Endocrine System Diseases Commons

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466 full-text articles. Page 17 of 17.

Self-Glucose Monitoring And Glycaemic Control At A Tertiary Care University Hospital, Karachi, Pakistan, Khurshid Khowaja, Humaira Waheed 2010 Aga Khan University

Self-Glucose Monitoring And Glycaemic Control At A Tertiary Care University Hospital, Karachi, Pakistan, Khurshid Khowaja, Humaira Waheed

Section of Diabetes, Endocrinology and Metabolism

OBJECTIVE: To explore the association between Self Monitoring of Blood Glucose (SMBG) levels and improved glycemic control (HbA1c level) among type 2 diabetic patients, receiving oral hypoglycaemic agents and insulin, and to ascertain the factors influencing SMBG.

METHOD: Using Comparative cross sectional study design five hundred Type 2 diabetes patients through convenient sampling between 30-70 years were interviewed through a structured questionnaire in year 2006 and 2007 at AKUH Ambulatory setting. These 500 subjects were divided as 250 in case (doing SMBG) and 250 in control (not doing SMBG) groups.

RESULTS: We identified that HbA1c value was maintained at good ...


Pufa And Vitamin D And Type 2 Diabetes Inflammatory Markers, Paulo Lotufo 2010 Universidade de São Paulo

Pufa And Vitamin D And Type 2 Diabetes Inflammatory Markers, Paulo Lotufo

Paulo A Lotufo

No abstract provided.


Chronic Diseases Epidemics: Myths And Facts [Portuguese], Paulo Lotufo 2010 Universidade de São Paulo

Chronic Diseases Epidemics: Myths And Facts [Portuguese], Paulo Lotufo

Paulo A Lotufo

a discussion about epidemiologic transition.


Imminent Epidemic Of Diabetes Mellitus In Pakistan: Issues And Challenges For Health Care Providers, Waris Qidwai, Tabinda Ashfaq 2010 Aga Khan University

Imminent Epidemic Of Diabetes Mellitus In Pakistan: Issues And Challenges For Health Care Providers, Waris Qidwai, Tabinda Ashfaq

Department of Family Medicine

No abstract provided.


Acl And Knee Injury Prevention Programs For Young Athletes: Do They Work?, K. Shea, N. Grimm, Shawn Simonson, J. Jacobs 2010 Boise State University

Acl And Knee Injury Prevention Programs For Young Athletes: Do They Work?, K. Shea, N. Grimm, Shawn Simonson, J. Jacobs

Shawn R. Simonson

No abstract provided.


Socioeconomic Status And Coronary Heart Disease Mortality In The City Of Sao Paulo, Brazil (1996 To 2007), Paulo Lotufo 2010 Universidade de São Paulo

Socioeconomic Status And Coronary Heart Disease Mortality In The City Of Sao Paulo, Brazil (1996 To 2007), Paulo Lotufo

Paulo A Lotufo

No abstract provided.


The Role Of Akt2 In Hepatic Lipid Metabolism, Karla F. Leavens 2010 Universiy of Pennsylvania

The Role Of Akt2 In Hepatic Lipid Metabolism, Karla F. Leavens

Publicly Accessible Penn Dissertations

Insulin drives the global anabolic response to nutrient ingestion, regulating both carbohydrate and lipid metabolism. When insulin resistance occurs in Type 2 Diabetes Mellitus, dysregulation of both of these processes ensues, resulting in hyperglycemia and lipid abnormalities. One of the most prevalent morbidities associated with insulin resistance is the abnormal accumulation of triglycerides in the liver, called hepatic steatosis, though the underlying pathogenesis of this accumulation remains unclear. There is certainly an inappropriate increase in de novo lipogenesis in the livers of individuals with hepatic steatosis, but the insulin signaling pathway involved in the control of normal, and therefore abnormal ...


Non-Inferiority Trials [In Portuguese], Paulo A. Lotufo 2010 Universidade de São Paulo

Non-Inferiority Trials [In Portuguese], Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.


Cardiovascular And Cancer Mortality In Brazil, Paulo Lotufo 2010 Universidade de São Paulo

Cardiovascular And Cancer Mortality In Brazil, Paulo Lotufo

Paulo A Lotufo

Cancer are not surpassing Cardiovascular Diseases. Here you have an evaluation of mortality in Brazil. The debate was ignited by paper from IARC (International Agency for Research on Cancer) that forecasts cancer deaths surpassing heart diseases rates during de 2020’s. There is no dispute about the fact that - at least in the US and other countries - the decline of mortality deaths for heart diseases presenting a faster pace compared to cancer death rates. It is an epidemiological evidence that must be analyzed and some headline fueling hype as “heart diseases as an old agenda of public health and medical ...


A Randomized Clinical Trial Comparing Low-Glycemic Index Versus Ada Dietary Education Among Individuals With Type 2 Diabetes, Yunsheng Ma, Barbara Olendzki, Philip Merriam, David Chiriboga, Annie Culver, Wenjun Li, James Hebert, Ira Ockene, Jennifer Griffith, Sherry Pagoto 2010 University of Massachusetts Medical School

A Randomized Clinical Trial Comparing Low-Glycemic Index Versus Ada Dietary Education Among Individuals With Type 2 Diabetes, Yunsheng Ma, Barbara Olendzki, Philip Merriam, David Chiriboga, Annie Culver, Wenjun Li, James Hebert, Ira Ockene, Jennifer Griffith, Sherry Pagoto

Yunsheng Ma

OBJECTIVE: We compared the effects of a low glycemic index (GI) diet with the American Diabetes Association (ADA) diet on glycosylated hemoglobin (HbA1c) among individuals with type 2 diabetes. METHODS: Forty individuals with poorly controlled type 2 diabetes were randomized to a low-GI or an ADA diet. The intervention, consisting of eight educational sessions (monthly for the first 6 mo and then at months 8 and 10), focused on a low-GI or an ADA diet. Data on demographics, diet, physical activity, psychosocial factors, and diabetes medication use were assessed at baseline and 6 and 12 mo. Generalized linear mixed models ...


The Effects Of Low-Protein Diet And Testosterone On Sex Hormone-Binding Globulin Capacity In Male Rabbits, Christopher Longcope, Sandra Yosha, R. Young, Stephen Baker, Lewis Braverman 2010 University of Massachusetts Medical School

The Effects Of Low-Protein Diet And Testosterone On Sex Hormone-Binding Globulin Capacity In Male Rabbits, Christopher Longcope, Sandra Yosha, R. Young, Stephen Baker, Lewis Braverman

Stephen P. Baker

The effects of a low-protein high-carbohydrate (LPHC) diet (8% protein 65% to 72% carbohydrate) were compared to those of regular rabbit chow (14% to 16% protein 57% to 64% carbohydrate) on sex hormone-binding globulin (SHBG) capacity in 12 male rabbits. The six rabbits who were fed the LPHC diet for 8 weeks showed a significant increase in their mean SHBG capacity (mean +/- SE: from 70 +/- 16 nmol/L to 332 +/- 45 nmol/L, P less than .01) whereas the six rabbits fed the standard diet showed a slight decrease (from 106 +/- 22 nmol/L to 76 +/- 20 nmol/L, NS ...


Cd57 (Leu-7) Expression Is Helpful In Diagnosis Of The Follicular Variant Of Papillary Thyroid Carcinoma, Ashraf Khan, Stephen Baker, Nilima Patwardhan, James Pullman 2010 University of Massachusetts Medical School

Cd57 (Leu-7) Expression Is Helpful In Diagnosis Of The Follicular Variant Of Papillary Thyroid Carcinoma, Ashraf Khan, Stephen Baker, Nilima Patwardhan, James Pullman

Stephen P. Baker

CD57 (HNK-1) is a oligosaccharide antigen that is expressed by cells of several lineages. It is present on multipotential neuroepithelial cells during embryogenesis, and tumours of epithelial, neuroectodermal and nerve sheath origin also express CD57. Its role in the diagnosis of thyroid tumours is controversial. We have studied CD57 expression by immunohistochemistry to determine its utility in the classification of thyroid follicular lesions. Study material included 114 normal thyroid sections, 77 benign thyroid lesions (29 colloid nodules, 22 follicular adenomas, 20 cases of Hashimoto's thyroiditis and 6 of Grave's disease) and 83 thyroid carcinomas, including 31 follicular variants ...


Tamoxifen Decreases Lipoprotein (A) In Patients With Breast Cancer, David Shewmon, John Stock, Lynda Abusamra, Mary Kristan, Stephen Baker, Kathleen Heiniluoma 2010 UMass Memorial Health Care

Tamoxifen Decreases Lipoprotein (A) In Patients With Breast Cancer, David Shewmon, John Stock, Lynda Abusamra, Mary Kristan, Stephen Baker, Kathleen Heiniluoma

Stephen P. Baker

An elevated concentration of lipoprotein(a) [Lp(a)] is a potent risk factor for coronary atherosclerosis. Recently, several hormonal agents including estrogen have been reported to decrease serum Lp(a) concentrations. We found that the antiestrogen tamoxifen also decreased Lp(a) concentrations approximately 40% in six patients with breast cancer, an effect that was achieved by 1 month of therapy and that was stable in five of six patients. If the Lp(a)-lowering effect of tamoxifen can be replicated in women without breast cancer, tamoxifen might be considered as an alternative to niacin for the treatment of elevated Lp ...


Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo Lotufo 2010 Universidade de São Paulo

Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo Lotufo

Paulo A Lotufo

No abstract provided.


Characteristics Of Small Areas With A Higher Stroke Mortality, Paulo Lotufo 2010 Universidade de São Paulo

Characteristics Of Small Areas With A Higher Stroke Mortality, Paulo Lotufo

Paulo A Lotufo

No abstract provided.


Higher Frequency Of Stroke Deaths On Monday And Saturday, Paulo Lotufo 2010 Universidade de São Paulo

Higher Frequency Of Stroke Deaths On Monday And Saturday, Paulo Lotufo

Paulo A Lotufo

No abstract provided.


Prevalence Of Metabolic Syndrome And Estimated Framingham Risk Score Among Brazilian Hiv-Infected Patients, Paulo Lotufo 2010 Universidade de São Paulo

Prevalence Of Metabolic Syndrome And Estimated Framingham Risk Score Among Brazilian Hiv-Infected Patients, Paulo Lotufo

Paulo A Lotufo

creased risk for cardiovascular disease (CVD). The 10-year Framingham risk score (FRS) is used to predict Cardiovascular events in the non-HIV-infected patients, and its application in the HIV-infected subjects is under Discussion. We evaluated the traditional CVD risk factors and metabolic syndrome (MS) components among HIVinfected patients ART-treated and ART-naïve. Methods: This was a cross-sectional study of HIV-infected subjects ART-treated (n = 29), HIVinfected patients ART-naive (n = 28) and controls without previous CVD events (n = 32). Subjects were selected for common age range (20 to 69 years) from the Instituto de Infectologia Emilio Ribas, São Paulo. We assessed cardiovascular risk factors ...


Social Inequalities And The Decline Of Stroke Mortality In The City Of Sao Paulo, Brazil, Paulo Lotufo 2010 Universidade de São Paulo

Social Inequalities And The Decline Of Stroke Mortality In The City Of Sao Paulo, Brazil, Paulo Lotufo

Paulo A Lotufo

No abstract provided.


Frequency Of Subclinical Thyroid Dysfunction And Risk Factors For Cardiovascular Disease Among Women At A Workplace, Paulo Lotufo 2009 Universidade de São Paulo

Frequency Of Subclinical Thyroid Dysfunction And Risk Factors For Cardiovascular Disease Among Women At A Workplace, Paulo Lotufo

Paulo A Lotufo

CONTEXT AND OBJECTIVE: Subclinical thyroid dysfunction is very common in clinical practice and there is some evidence that it may be associated with cardiovascular disease. The aim here was to evaluate the frequencies of subclinical thyroid disease and risk factors for cardiovascular disease among women at a workplace, and to evaluate the association between subclinical thyroid disease and cardiovascular risk factors among them. DESIGN AND SETTING: Cross-sectional study on 314 women aged 40 years or over who were working at Universidade de São Paulo (USP). METHODS: All the women answered a questionnaire on sociodemographic characteristics and risk factors for cardiovascular ...


Subclinical Hyperthyroidism And Dementia: The Sao Paulo Ageing & Health Study (Spah), Paulo Lotufo 2009 Universidade de São Paulo

Subclinical Hyperthyroidism And Dementia: The Sao Paulo Ageing & Health Study (Spah), Paulo Lotufo

Paulo A Lotufo

Background: Several epidemiologic studies have shown a possible association between thyroid function and cognitive decline. Our aim was to evaluate the association of subclinical hyperthyroidism and dementia in a population sample of older people. Methods: A cross-sectional study - São Paulo Ageing & Health Study (SPAH) - in a population sample of low-income elderly people ≥ 65 years-old to evaluate presence of subclinical thyroid disease as a risk factor for dementia. Thyroid function was assessed using thyrotropic hormone and free-thyroxine as well as routine use of thyroid hormones or antithyroid medications. Cases of dementia were assessed using a harmonized one-phase dementia diagnostic procedure by the "10/66 Dementia Research Group" including Alzheimer's disease and vascular dementia. Logistic regression models were used to test a possible association between subclinical hyperthyroidism and dementia. Results and discussion: Prevalence of dementia and of subclinical hyperthyroidism were respectively of 4.4% and 3.0%. After age adjustment, we found an association of subclinical hyperthyroidism and any type of dementia and vascular dementia (Odds Ratio, 4.1, 95% Confidence Interval [95% CI] 1.3-13.1, and 5.3 95% CI, 1.1-26.4; respectively). Analyzing data by gender, we found an association of subclinical hyperthyroidism with dementia and Alzheimer's disease only for men (OR, 8.0; 95% CI, 1.5-43.4; OR, 12.4; 95% CI, 1.2-128.4; respectively). No women with subclinical hypothyroidism presented Alzheimer's disease in the sample. Conclusion: The results suggest a consistent association among people ...


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