Dental Materials Commons^™

Part I: Comparative Analysis Between Natural And Ceramic Teeth, Aneeza Hussain, Ibeth Erazo

Publications and Research

Ceramics play a fundamental role in Dentistry and are used widely, due to their ability to mimic the optical characteristics of enamel and dentine, as well as for their biocompatibility and strength. Initially, dental ceramics were materials that formed part of systems, designed with the purpose of producing dental prosthetics that in turn were used to replace missing or damaged dental structures. However, due to the increased demand for esthetics, its development has gone beyond in such a way that it has led to the development of all ceramic restorations. So that, in the last few decades, there have been …

Nell-1 Is A Key Functional Modulator In Osteochondrogenesis And Beyond, C. Li, X. Zhang, Z. Zheng, A. Nguyen, K. Ting, C. Soo

Departmental Papers (Dental)

Neural EGFL-like 1 (Nell-1) is a well-studied osteogenic factor that has comparable osteogenic potency with the Food and Drug Administration–approved bone morphogenic protein 2 (BMP-2). In this review, which aims to summarize the advanced Nell-1 research in the past 10 y, we start with the correlation of structural and functional relevance of the Nell-1 protein with the identification of a specific receptor of Nell-1, contactin-associated protein-like 4 (Cntnap4), for osteogenesis. The indispensable role of Nell-1 in normal craniofacial and appendicular skeletal development and growth was also defined by using the newly developed tissue-specific Nell-1 knockout mouse lines in addition to …

Efficacy Of A Dissolvable Strip With Calcium Sodium Phosphosilicate (Novamin®) In Providing Rapid Dentine Hypersensitivity Relief, John Gallob, Martin R. Ling, Pejmon Amini, Avinash Patil, Mounir Atassi

Dental Medicine Faculty Publications

Objective To evaluate the efficacy of a dissolvable strip containing 15% w/w calcium sodium phosphosilicate (CSPS) (Novamin®) in providing rapid relief from dentine hypersensitivity (DH). Methods In this examiner-blind, proof-of-principle study, 120 healthy adults with DH were randomized 1:1 to the Test strip, professionally applied to facial surfaces of two selected teeth, or to No treatment. Sensitivity was assessed at baseline and 10 min, 2 h and 4 h post-application in response to evaporative (air) and tactile stimuli (measured by Schiff sensitivity scale/a numeric rating scale and tactile threshold, respectively). Change from baseline was analyzed by ANCOVA. Results At 10 …

Marginal Staining Between Pressed Lithium Disilicate Ceramic Crowns And Direct Restorative Materials By Various Fluids : A Microleakage Study., Sarah Ann Jestel

Electronic Theses and Dissertations

When treating patients with existing restorations in which indirect restoration placement is indicated and crown lengthening surgery is contraindicated, dentists may choose to finish the crown margin on an existing restoration. The interface between the two dental restorations (resin composite and ceramic crown) may be more susceptible to microleakage and fluid staining, reducing restoration longevity. In this study, 80 extracted molars received indirect restoration margins finished on different direct restorative materials (resin-modified glass ionomer and conventional, flowable, and bulk fill nano-hybrid resin composite) and subjected to common staining fluids of coffee, tea, red wine, or Coca-Cola. If the clinician must …

Mass Spectrometry-Based Proteomics Analysis Of Bioactive Proteins In Emd That Modulate Adhesion Of Gingival Fibroblast To Improve Bio-Integration Of Dental Implants, David Zuanazzi Machado Jr

Electronic Thesis and Dissertation Repository

Titanium implants are used in dental practice to replace damaged or lost teeth. The implant needs to integrate with the surrounding gingiva to protect it against bacterial invasion that leads to implant loss. The biointegration is dependent on the implant surface that interacts with proteins from biological fluids to modulate tissues response. Tailoring the surface with specific proteins from the enamel matrix derivative (EMD) would be beneficial to improve the implant-gingiva interface since EMD can affect various cells including gingival fibroblasts. A surface-affinity approach using three different titanium surfaces and saliva was utilized as a model in combination with tandem …

To Repair Or Replace: That Is The Restorative Question, Juhstin M. Brown, Clement S. Augustus

Dental Hygiene Student Scholarship

Objective/Aims: During dental visits, patients spend the majority of their time with their dental hygienist. At these recall appointments the patient’s face-to-face time with the dentist may be short. At this part of the appointment the dentist may diagnose the need for restorative treatment for the patient. Part of the hygienist’s responsibility is to explain treatment options for teeth with restorative needs. The purpose of this review of literature is to provide both options for restoration of dentition to a functional/aesthetic state.

Methods: Studies pertaining to the topic were searched using PubMed database. Keywords used in the search were amalgam, …

Remote Corticotomy Accelerates Orthodontic Tooth Movement In A Rat Model, Nin Zou, Chenshuang Li, Zhong Zheng

Departmental Papers (Dental)

Introduction. With an increasing demand for orthodontic treatment for adult patients, orthodontic professionals are constantly seeking novel strategies and technologies that can accelerate tooth movement in order to shorten the treatment period. For instance, in recent years, the influences of different surgical techniques on orthodontic tooth movement in the ipsilateral side of surgery were intensively investigated. Here, we attempt to examine if corticotomy could also affect the rate of tooth movement in the contralateral side of the surgery by using a rodent model. Materials and Methods. 72 eight-week-old Sprague-Dawley rats were randomly divided into three groups as follows: The Control …

Apexification Management Of Mandibular Second Premolar With A Blunderbuss Apex And Periapical Lesion Of An Adult Patient, Chenshuang Li, Zhong Zheng, Xiaohong Deng, Lan Zhang, Baoyan Wang, Qingyu Guo, Min Zou

Departmental Papers (Dental)

Apexification is widely applied in teenager patients but rarely used in the adult population. Instead, artificial apical barrier with mineral trioxide aggregate (MTA) is clinically accepted, and spontaneous apical closure in nonvital immature teeth of adult patients has rarely been encountered while only apexification of the maxillary incisors in adult patients has been reported. The aim of this case report is to share a successful apexification application in the mandibular premolar with a blunderbuss apex and periapical lesion of an adult patient by using calcium hydroxide: radiographically, spontaneous hard tissue barrier has been established, and narrowing canal space and decreasing …

Effect Of Shear Bond Strength With Novel Apc™ Flash-Free Brackets And Different Bonding Protocol: An In Vitro Study, Carl Bernstein

Graduate Theses, Dissertations, and Problem Reports

Background and Objectives: In today’s time, there is an increasingly crowded field of competition vying over a small subset of the population. Now, more than ever it is imperative to compete with efficiency and esthetics. Each step for orthodontic bonding procedures increases the chance for error to occur. However, orthodontic bracket, etchant, sealant, and adhesive material has the ability to improve bond strength and final outcome for the patient and provider. The aim of this study was to determine effective bonding protocols for Advanced Clarity APC™ Flash-Free Brackets and to determine if adhesive remains on enamel or orthodontic bracket after …

Designing Biomimetic Implant Surfaces To Promote Osseointegration Under Osteoporotic Conditions By Revitalizing Mechanisms Coupling Bone Resorption To Formation, Ethan M. Lotz

Theses and Dissertations

In cases of compromised bone remodeling like osteoporosis, insufficient osseointegration occurs and results in implant failure. Implant retention relies on proper secondary fixation, which is developed during bone remodeling. This process is disrupted in metastatic bone diseases like osteoporosis. Osteoporosis is characterized low bone mass and bone strength resulting from either accelerated osteoclast-mediated bone resorption or impaired osteoblast-mediated bone formation. These two processes are not independent phenomena. In fact, osteoporosis can be viewed as a breakdown of the cellular communication connecting bone resorption to bone formation. Because bone remodeling occurs at temporally generated specific anatomical sites and at different times, …

The Efficacy Of A Fluoride-Containing Orthodontic Primer In Preventing Demineralization, Alyssa G. Ricci

Theses and Dissertations

Purpose: To evaluate the efficacy of a fluoride-containing orthodontic primer in preventing demineralization adjacent to brackets and compare the quality of enamel on tooth surfaces that received interproximal reduction (IPR).

Methods: Patients at the VCU Orthodontic clinic who consented to orthodontic treatment involving extraction of at least 2 premolars were recruited to this pilot clinical study. Brackets were bonded to premolars using one of two primers, fluoride-containing experimental or control. IPR was also performed, and the experimental primer was applied to randomly selected teeth. Extracted teeth were analyzed visually for the presence of white spot lesions (WSLs). Micro-CT analyses were …

Effect Of Clear Aligner Therapy On Masticatory Muscle Tenderness And Orthodontic Pain, Johnny Tran

Electronic Thesis and Dissertation Repository

Introduction: Patients undergoing orthodontic clear aligner therapy (CAT) may experience discomfort in their teeth and jaws, and often present with visible wear on their aligners. This multi-site prospective clinical study aimed to analyze tooth pain and masticatory muscle tenderness in patients subjected to CAT with Invisalign©.

Methods: Twenty-seven healthy adults undergoing treatment with Invisalign© were recruited from three university-based orthodontic clinics. Tooth pain and muscle tenderness were reported on visual analog scales in pain diaries prior to, and after starting CAT. Pressure pain thresholds (PPT) measured using pressure algometers were used to assess somatosensory changes in trigeminal and extra-trigeminal locations. …

Design Of Parallel Robot For Dental Articulation And Its Optimization, Abulimiti Delimulati

Mechanical (and Materials) Engineering -- Dissertations, Theses, and Student Research

A dental articulator is a mechanical device used to simulate the relative position and motion between the upper and lower jaw when constructing and testing dental prostheses. Typically, it can be adjusted to approximate patient-specific jaw kinematics in order to analogue the static relationship and specific motions of a patient’s mandible to maxilla. However, the use of dental articulators is essentially a trial-and-error method in order to fine-tune fit and function of a dental prosthesis. Some of the most advanced current dental articulators can reproduce the position and the motion passively; furthermore, dentists need special training for measuring patients’ maxillofacial …

Orthodontic Bond Strength Comparison Between Two Filled Resin Sealants, James Kolstad

Master's Theses (2009 -)

Introduction: Sealants are used in orthodontics to help prevent demineralization during treatment. The objective of this study was to determine if there is a difference in the shear bond strength (SBS) between two different resin sealants bonded to teeth. Materials and Methods: Extracted human premolars (n=20/group) were randomly divided and prepared by acid etching, followed by application of primer or sealant. Group 1, the control group, used Transbond XT Primer (3M Unitek). Groups 2 and 3 were prepared with the sealants L.E.D. Pro Seal (Reliance Orthodontic Products) and Opal Seal (Opal Orthodontics) respectively. Transbond XT Adhesive was applied to a …

Managing Patient Expectations With Implant Treatment, Daniel B. Kamran, Mark Booth Dds, Eduardo Gonzalez Dds, Ed Shaw Dds

Excellence Day

This patient came to University of the Pacific, Arthur A. Dugoni School of Dentistry to get implants and implant crowns to improve his smile, replacing his upper partial denture. Different approaches were made by the faculty to arrive at best outcomes, which took four years for the patient to receive the treatment he wanted. This abstract will further detail how the treatment was conducted and the results afterwards.

Evaluation Of The Biocompatibility And Micromechanical Properties Of Experimental Dental Adhesives, Hoda Moussa

Forensic Science Theses

The purpose of this study was to investigate the biocompatibility and micromechanical properties of newly synthesized antibacterial monomer and cross-linker functional surfactants into a commercially available dental adhesive (Single Bond, 3M ESPE, Saint Paul, MN, USA) at three concentrations (0.05, 0.1, 0.25 mg/mg). All groups were analyzed by evaluation of micro-tensile bond strength, ultimate tensile strength, cell viability, antibacterial properties, and surface micro-hardness. Scanning electron microscopy (SEM) was used for interfacial characterization.

Human extracted molars were used as a substrate for bonding adhesives for the micro-tensile bond strength (MTBS) and scanning electron microscopy (SEM) studies. Twenty resin-dentin beams (0.9 ± …

Effect Of Porcelain Thickness And Translucency On The Final Shade Of Ips E.Max Cad Overlaying A Dark Substrate., Peter F. Alena

Electronic Theses and Dissertations

IPS e.max is a very esthetic lithium disilicate used in dental ceramics. Unfortunately, it can unintentionally change color after cementation with resin cements. The purpose of this study is to better understand how combining thickness and translucency affects the post-cementation shade of IPS e.max CAD overlaying a dark substrate, thereby enabling clinicians to choose more appropriate techniques and materials. IPS e.max CADs (A1 shade) had either a low translucency (LT) or high translucency (HT), and cut with 0.3mm, 0.5mm, and 1.0mm thicknesses. Each sample overlaid a resin cement and dark substrate, a spectrophotometer helped derive the color difference (ΔE*ab), and …

1st Place Contest Entry: Provisional Patent Research Process, Joshua Goldfaden

Kevin and Tam Ross Undergraduate Research Prize

This is Joshua Goldfaden's submission for the 2018 Kevin and Tam Ross Undergraduate Research Prize, which won first place. He wrote about abrasive chemicals in commercial toothpastes and created a provisional patent to develop a safer alternative.

Joshua is a sophomore at Chapman University, majoring in Biochemistry and Molecular Biology. His faculty mentor is Dr. Yu-An (Peter) Chang.

Chlorine Stain And The Oral Cavity, Alexandra B. Moore

Dental Hygiene ETDs

Swimming is known worldwide as one of the healthiest, low-impact forms of exercise and for the subsequent promotion of a strong body, heart, and mind. However, many swimmers and non-swimmers do not realize that swimming in a pool can have a negative effect on the oral cavity. Several studies have suggested that pool chlorination is responsible for dental erosion, calculus formation, and stain in competitive and recreational swimmers, and this phenomenon is known as ‘swimmer’s mouth.’ A pilot experimental research study was conducted that evaluated the prevalence of chlorine stain in the oral cavity of twenty-one female swimmers from the …

Fibromodulin Reduces Scar Size And Increases Scar Tensile Strength In Normal And Excessive-Mechanical-Loading Porcine Cutaneous Wounds, Wenlu Jiang, Kang Ting, Soonchul Lee, Janette N. Zara, Richard Song, Chenshuang Li, Eric Chen, Xinli Zhang, Zhihe Zhao, Chia Soo, Zhong Zheng

Departmental Papers (Dental)

Hypertrophic scarring is a major postoperative complication which leads to severe disfigurement and dysfunction in patients and usually requires multiple surgical revisions due to its high recurrence rates. Excessive-mechanical-loading across wounds is an important initiator of hypertrophic scarring formation. In this study, we demonstrate that intradermal administration of a single extracellular matrix (ECM) molecule—fibromodulin (FMOD) protein—can significantly reduce scar size, increase tensile strength, and improve dermal collagen architecture organization in the normal and even excessive-mechanical-loading red Duroc pig wound models. Since pig skin is recognized by the Food and Drug Administration as the closest animal equivalent to human skin, and …