Association Between Craniofacial Anomalies And Newborn Hearing Screening Fail Rate, 2022 Gallaudet University
Association Between Craniofacial Anomalies And Newborn Hearing Screening Fail Rate, Kaitlyn Sheapp, Ruth S. Marin, Larry Medwetsky
Journal of Early Hearing Detection and Intervention
Purpose: Increased knowledge of the prevalence of various craniofacial anomalies and their associated risks for hearing loss can help guide 1) development of evidence-based practice regarding detection and documentation of risk factors at birth and 2) health care professionals to make appropriate recommendations for follow-up testing and monitoring.
Method: Records were reviewed for 39,813 infants born at Adventist HealthCare Shady Grove Medical Center and White Oak Medical Center between January 1, 2014 and December 31, 2019 to determine the association between the presence of craniofacial anomalies and newborn hearing screening fail rates, as well as the prevalence of confirmed ...
Vision Anatomy, 2022 University of Alabama, Birmingham
Vision Anatomy, Juliana Coleman
PEER Liberia Project
This presentation is Lecture 2 in the PEER Liberia Neurology Lecture Series. It provides an overview of eye anatomy, vision testing, and diagnosis of eye conditions.
Otorhinolaryngology Consultations In A Multidisciplinary Hospital - Their Effects On Residents Training On Floor, Ambreen Abdullah Unar, Muhammad Hammad Deewani, Mohammad Sohail Awan, Syeda Amrah Hashmi, Abdul Basit Shah Vardag, Ainulakbar Mughal
Section of Otolaryngology, Head & Neck Surgery
Objective: To determine all types and severity of Otolaryngology consultation requests at our tertiary care center and spectral records of problems related to otorhinolaryngology come across initially by residents which will help in re-shaping residency programmes and enhance patient related care.
Methodology: All otorhinolaryngology consultation received over a three-month period were recorded prospectively. Information collected for each encounter included the time, date, reason for consult at primary service and admission with final ENT diagnosis, any surgical or non-surgical intervention, and basic patient demographics.
Results: A total of 127 consults for inpatients were reviewed from April 2020 to June 2020. Out ...
Eye Movement And Pupil Measures: A Review, 2022 Old Dominion University
Eye Movement And Pupil Measures: A Review, Bhanuka Mahanama, Yasith Jayawardana, Sundararaman Rengarajan, Gavindya Jayawardena, Leanne Chukoskie, Joseph Snider, Sampath Jayarathna
Computer Science Faculty Publications
Our subjective visual experiences involve complex interaction between our eyes, our brain, and the surrounding world. It gives us the sense of sight, color, stereopsis, distance, pattern recognition, motor coordination, and more. The increasing ubiquity of gaze-aware technology brings with it the ability to track gaze and pupil measures with varying degrees of fidelity. With this in mind, a review that considers the various gaze measures becomes increasingly relevant, especially considering our ability to make sense of these signals given different spatio-temporal sampling capacities. In this paper, we selectively review prior work on eye movements and pupil measures. We first ...
Resetting Of Auditory And Visual Segregation Occurs After Transient Stimuli Of The Same Modality, 2021 University of Nevada, Las Vegas
Resetting Of Auditory And Visual Segregation Occurs After Transient Stimuli Of The Same Modality, Nathan C. Higgins, Ambar G. Monjaras, Breanne D. Yerkes, David F. Little, Jessica E. Nave-Blodgett, Mounya Elhilali, Joel S. Snyder
Psychology Faculty Publications
In the presence of a continually changing sensory environment, maintaining stable but flexible awareness is paramount, and requires continual organization of information. Determining which stimulus features belong together, and which are separate is therefore one of the primary tasks of the sensory systems. Unknown is whether there is a global or sensory-specific mechanism that regulates the final perceptual outcome of this streaming process. To test the extent of modality independence in perceptual control, an auditory streaming experiment, and a visual moving-plaid experiment were performed. Both were designed to evoke alternating perception of an integrated or segregated percept. In both experiments ...
Comprehensive Review And Update Of Burning Eye Syndrome, 2021 Creighton University School of Medicine
Comprehensive Review And Update Of Burning Eye Syndrome, Stephen Giacomazzi, Ivan Urits, Briggs Hoyt, Ashley Hubble, Elyse M. Cornett, Kyle Gress, Karina Charipova, Amnon A. Berger, Hisham Kassem, Alan D. Kaye, Omar Viswanath
Journal of Patient-Centered Research and Reviews
Keratoconjunctivitis sicca (“dry eye”) is a common (14%–30% of adults over age 48) though difficult to treat condition that causes both discomfort and disability with associated dryness, pain, and visual disturbances. Etiology is not clearly understood but is likely varied, with a subset of patients suffering from chronic neuropathic pain referred to as “burning eye syndrome.” This review of existing literature summarizes the clinical presentation, natural history, pathophysiology, and treatment modalities of burning eye syndrome.
Chronicity of burning eye syndrome is likely secondary to increased nociception from the cornea, decrease in inhibitory signals, and nerve growth factor expression alterations ...
Differential Effect Of Proinflammatory Cytokines On Corneal And Conjunctival Epithelial Cell Mucins And Glycocalyx, Kiumars Shamloo, Priya Mistry, Ashley Barbarino, Christopher Ross, Vishal Jhanji
Pharmacy Faculty Articles and Research
Purpose: Ocular surface mucins and glycocalyx are critical for providing ocular hydration as well lubrication and repelling pathogens or allergens. Elevated levels of tear proinflammatory cytokines in dry eye may have detrimental effect on mucins and glycocalyx. The present study tested the effect of proinflammatory cytokines IL-6, TNF-α, and IFN-γ on membrane-tethered mucins expression, glycocalyx, and viability of ocular surface epithelial cells.
Methods: Stratified cultures of human corneal and conjunctival epithelial cells were exposed to different concentrations of IL-6, TNF-α, and IFN-γ for 24 hours. The mucins gene and protein expressions were quantified by real-time polymerase chain reaction (PCR) and ...
Terson-Like Syndrome Associated With Familial Retinal Arteriolar Tortuosity (Frat) And A Spontaneous Spinal Hemorrhage, Peter Maduka, David R. Lally
Stratford Campus Research Day
Background: Familial retinal arteriolar tortuosity (fRAT) is an autosomal dominant disorder that is characterized by tortuosity of the second and third order retinal arterioles in the macular and peripapillary areas. The genetics of fRAT are incompletely understood but have been associated with a missense mutation in the COL4A1 gene in some cases. fRAT is not typically associated with visual loss and prognosis is good. However, the tortuous arterioles can bleed, causing intraretinal, preretinal, and/or subretinal hemorrhages.
Objective: To describe a case of Terson-like syndrome associated with familial retinal arteriolar tortuosity (fRAT) in the setting of spontaneous spinal hemorrhage.
Retinal Vasculitis: A Case Study, 2021 Rowan University
Retinal Vasculitis: A Case Study, Peter Maduka, Sarah G. Bonaffini, Naman Shah, Deepika Malik
Stratford Campus Research Day
Purpose: To describe a case of idiopathic retinal vasculitis.
Methods: Case report and literature review.
Case: A healthy 25-year-old female presented with a one-week history of a large floater in her right eye. Patient’s subjective complaint of floaters, including the scotoma on VF and the FA findings were most consistent with retinal vasculitis displaying predominant venous involvement. However, findings for acute macular neuroretinopathy and multiple evanescent white dot syndrome (MEWDS) were present as well. Autoimmune and infectious disease panels were negative. Neuro consult and brain MRI showed nonspecific, non contributory findings. Several weeks later, following Medrol dose pack, patient ...
Monopolar Gene Electrotransfer Enhances Plasmid Dna Delivery To Skin, 2021 Old Dominion University
Monopolar Gene Electrotransfer Enhances Plasmid Dna Delivery To Skin, Anna Bulysheva, Loree Heller, Michael Francis, Frency Varghese, Carly Boye, Richard Heller
Electrical & Computer Engineering Faculty Publications
A novel monopolar electroporation system and methodologies were developed for in vivo electroporation intended for potential clinical applications such as gene therapy. We hypothesized that an asymmetric anode/cathode electrode applicator geometry could produce favorable electric fields for electroporation, without the typical drawback associated with traditional needle and parallel plate geometries. Three monopolar electrode applicator prototypes were built and tested for gene delivery of reporter genes to the skin in a guinea pig model. Gene expression was evaluated in terms of kinetics over time and expression distribution within the treatment site. Different pulsing parameters, including pulse amplitude, pulse duration, and ...
Open Neuroscience Initiative, 2021 DePaul University
Open Neuroscience Initiative, Austin Lim
College of Science and Health Full Text Publications
The Open Neuroscience Initiative is a free-to-use textbook
This project began as a means to overcoming the financial burden that face undergraduate neuroscience students when buying textbooks. By compiling and writing a completely free-to-access textbook that covers the foundations of a typical college introduction to neuroscience course, students would have one less obstacle to overcome in their educational career, allowing them to focus their valuable time and attention on learning rather than finances. To make this project a reality, I began with a humble tweet in May 2019 that managed to gain a tiny bit of traction among the neuroscience ...
Metachronous Eyelid Basal Cell Carcinoma On Opposite Eye And Lid: A Case Report, 2020 Northport Veterans Affairs Medical Center
Metachronous Eyelid Basal Cell Carcinoma On Opposite Eye And Lid: A Case Report, Danielle C. Kalberer Od, Faao, Matthew A. Delmauro Md
Optometric Clinical Practice
Background: Basal cell carcinoma (BCC) is the most common eyelid malignancy, accounting for approximately 90% of malignant eyelid lesions.1 Despite its high occurrence rates, it is frequently misdiagnosed as one of the benign “lumps and bumps” that can be present on the eyelid. In the present case, a patient with a past BCC on the right upper eyelid presented with a left lower eyelid lesion which persisted for months before the patient sought evaluation by an eyecare provider. This benign-looking lash-line lesion was the only external sign of the malignancy found on the deep surface of the eyelid and ...
Ophthalmology Lecture 1: Ophthalmology Fundamentals, 2020 Sunyani SDA Hospital
Ophthalmology Lecture 1: Ophthalmology Fundamentals, Louis Oteng-Gyimah
PEER Liberia Project
The goals of this presentation are: to provide an introduction to the responsibilities of an ophthalmologist and to ophthalmology as a medical specialty; to review the clinically relevant anatomy of the eye; to review the epidemiology of blindness and visual impairment; and to provide an overview of refractive errors and presbyopia.
Myo/Nog Cells Expressing Muscle Proteins Are Present In Preretinal Membranes From Patients With Proliferative Vitreoretinopathy., 2020 Philadelphia College of Osteopathic Medicine
Myo/Nog Cells Expressing Muscle Proteins Are Present In Preretinal Membranes From Patients With Proliferative Vitreoretinopathy., Jacquelyn Gerhart, Nathan Morrison, Lindsay Gugerty, David Telander, Arturo Bravo Nuevo, Mindy George-Weinstein
PCOM Scholarly Papers
Proliferative vitreoretinopathy (PVR) is a complication of rhegmatogenous retinal detachment and ocular trauma. The disease is characterized by development of membranes that may apply traction to the retina and cause redetachment. Membrane contractions are attributed to myofibroblasts arising from retinal pigment epithelial cells, glia and fibroblasts. The progenitors of myofibrobasts in the lens are Myo/Nog cells that express the skeletal muscle transcription factor MyoD and bone morphogenetic protein inhibitor Noggin. The retina and choroid also contain Myo/Nog cells that respond to stress. We examined preretinal PVR membranes from three ocular trauma patients with retinal detachment for Myo/Nog ...
The Effect Of Hypoxia On Brain Cell Proliferation In Weakly Electric Fish, Petrocephalus Degeni, Kaitlin Klovdahl
Senior Theses and Projects
Oxygen levels tend to remain at a steady state concentration in the Earth’s atmosphere, yet in some bodies of water, they can fluctuate and decrease drastically. Many organisms that inhabit the swamps, lakes, streams, and parts of the ocean where this occurs have evolved adaptations to manage this environmental uncertainty and continue normal oxygen consumption. The Lwamunda swamp in Uganda is chronically hypoxic, yet it is home to many species, including the electric fish Petrocephalus degeni. P. degeni are unusual by nature of their immense brain, and the Lwamunda swamp appears ill-suited for maintaining this large, metabolically active organ ...
A Case Study On Accessible Reading With Deaf Children, 2020 Old Dominion University
A Case Study On Accessible Reading With Deaf Children, Jody H. Cripps, Samuel J. Supalla, Laura A. Blackburn
Communication Disorders & Special Education Faculty Publications
The concept of accessible reading for deaf students is new and worthy of exploration. In the face of the reading difficulties often experienced by deaf students, the lack of a specialized reading methodology that works for them must be addressed. Central to the paper is a research case study undertaken with two young deaf students, proficient in American Sign Language (ASL) and learning to read. The students participated in a tutorial with a tutor knowledgeable in a specialized reading methodology called ASL Gloss. The participating students demonstrated progress in reading skills over time. Two reading measures were adapted from English ...
Sail: Saliency-Driven Injection Of Aria Landmarks, 2020 Old Dominion University
Sail: Saliency-Driven Injection Of Aria Landmarks, Ali Selman Aydin, Shirin Feiz, Vikas Ashok, Iv Ramakrishnan
Computer Science Faculty Publications
Navigating webpages with screen readers is a challenge even with recent improvements in screen reader technologies and the increased adoption of web standards for accessibility, namely ARIA. ARIA landmarks, an important aspect of ARIA, lets screen reader users access different sections of the webpage quickly, by enabling them to skip over blocks of irrelevant or redundant content. However, these landmarks are sporadically and inconsistently used by web developers, and in many cases, even absent in numerous web pages. Therefore, we propose SaIL, a scalable approach that automatically detects the important sections of a web page, and then injects ARIA landmarks ...
Towards Making Videos Accessible For Low Vision Screen Magnifier Users, 2020 Old Dominion University
Towards Making Videos Accessible For Low Vision Screen Magnifier Users, Ali Selman Aydin, Shirin Feiz, Vikas Ashok, Iv Ramakrishnan
Computer Science Faculty Publications
People with low vision who use screen magnifiers to interact with computing devices find it very challenging to interact with dynamically changing digital content such as videos, since they do not have the luxury of time to manually move, i.e., pan the magnifier lens to different regions of interest (ROIs) or zoom into these ROIs before the content changes across frames.
In this paper, we present SViM, a first of its kind screen-magnifier interface for such users that leverages advances in computer vision, particularly video saliency models, to identify salient ROIs in videos. SViM's interface allows users to ...
Rotate-And-Press: A Non-Visual Alternative To Point-And-Click, 2020 Old Dominion University
Rotate-And-Press: A Non-Visual Alternative To Point-And-Click, Hae-Na Lee, Vikas Ashok, I. V. Ramakrishnan
Computer Science Faculty Publications
Most computer applications manifest visually rich and dense graphical user interfaces (GUIs) that are primarily tailored for an easy-and-efficient sighted interaction using a combination of two default input modalities, namely the keyboard and the mouse/touchpad. However, blind screen-reader users predominantly rely only on keyboard, and therefore struggle to interact with these applications, since it is both arduous and tedious to perform the visual 'point-and-click' tasks such as accessing the various application commands/features using just keyboard shortcuts supported by screen readers.
In this paper, we investigate the suitability of a 'rotate-and-press' input modality as an effective non-visual substitute for ...
Robotically Steered Needles: A Survey Of Neurosurgical Applications And Technical Innovations, 2020 Old Dominion University
Robotically Steered Needles: A Survey Of Neurosurgical Applications And Technical Innovations, Michel A. Audette, Stéphane P.A. Bordas, Jason E. Blatt
Computational Modeling & Simulation Engineering Faculty Publications
This paper surveys both the clinical applications and main technical innovations related to steered needles, with an emphasis on neurosurgery. Technical innovations generally center on curvilinear robots that can adopt a complex path that circumvents critical structures and eloquent brain tissue. These advances include several needle-steering approaches, which consist of tip-based, lengthwise, base motion-driven, and tissue-centered steering strategies. This paper also describes foundational mathematical models for steering, where potential fields, nonholonomic bicycle-like models, spring models, and stochastic approaches are cited. In addition, practical path planning systems are also addressed, where we cite uncertainty modeling in path planning, intraoperative soft tissue ...