Nervous System Commons

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Recent Articles in Nervous System

Human Enteric Glial Cells Alleviate Damaged Adult Sensory Neurons In Rats, Dhara Shah, Cai Jiang, Kiran Reddy, Caixin Su, Shucui Jiang McMaster University

Human Enteric Glial Cells Alleviate Damaged Adult Sensory Neurons In Rats, Dhara Shah, Cai Jiang, Kiran Reddy, Caixin Su, Shucui Jiang

The Meducator

Spinal cord injury affects millions across the globe. Little is known regarding the cellular mechanism of injury and, unfortunately, there are few viable treatment options. One potential option is the transplantation of peripheral nerves into the site of injury. The complicating factor is that the peripheral nervous system is not readily accessible, and thus the procedure introduces the risk of disrupting the function of other areas. However, this risk is minimized if the nerves are extracted from the enteric system, which is embedded in the lining of the gastrointestinal tract. This system bears similarities to the central nervous system, has ...


Sex Differences In Cell Death And Steroid Hormone Receptors In Cortical Explants, Amanda L. Trout University of Kentucky

Sex Differences In Cell Death And Steroid Hormone Receptors In Cortical Explants, Amanda L. Trout

Theses and Dissertations--Physiology

Estrogens, such as the biologically active 17-b estradiol (E2) have many actions in the male and female brain. Not only does E2 regulate reproductive behavior in adults, it organizes and activates the brains of younger animals in a sex-specific manner. In addition, many human studies have shown E2 to provide protection against a variety of neurological disorders, including stoke. These studies have been controversial and depend largely on the type and timing of hormone replacement. Animal studies are much less controversial and clearly demonstrate a neuroprotective role for E2 following ischemic brain injury. Because much of E2 neuroprotection requires sex ...


Multimodal Imaging Of The Self-Regulating Developing Brain, Anders M. Fjell, Kristine Beate Walhovd, Timothy T. Brown, Joshua M. Kuperman, Yoonho Chung, Donald J. Hagler Jr., Vijay Venkatraman, J. Cooper Roddey, Matthew Erhart, Connor McCabe, Natacha Akshoomoff, David G. Amaral, Cinnamon S. Bloss, Ondrej Libiger, Burcu F. Darst, Nicholas J. Schork, B. J. Casey, Linda Chang, Thomas M. Ernst, Jeffrey R. Gruen, Walter E. Kaufmann, Tal Kenet, Jean A. Frazier, Sarah S. Murray, Elizabeth R. Sowell, Peter van Zijl, Stewart Mostofsky, Terry L. Jernigan, Anders Dale University of Massachusetts Medical School

Multimodal Imaging Of The Self-Regulating Developing Brain, Anders M. Fjell, Kristine Beate Walhovd, Timothy T. Brown, Joshua M. Kuperman, Yoonho Chung, Donald J. Hagler Jr., Vijay Venkatraman, J. Cooper Roddey, Matthew Erhart, Connor Mccabe, Natacha Akshoomoff, David G. Amaral, Cinnamon S. Bloss, Ondrej Libiger, Burcu F. Darst, Nicholas J. Schork, B. J. Casey, Linda Chang, Thomas M. Ernst, Jeffrey R. Gruen, Walter E. Kaufmann, Tal Kenet, Jean A. Frazier, Sarah S. Murray, Elizabeth R. Sowell, Peter Van Zijl, Stewart Mostofsky, Terry L. Jernigan, Anders Dale

Psychiatry Publications and Presentations

Self-regulation refers to the ability to control behavior, cognition, and emotions, and self-regulation failure is related to a range of neuropsychiatric problems. It is poorly understood how structural maturation of the brain brings about the gradual improvement in self-regulation during childhood. In a large-scale multicenter effort, 735 children (4-21 y) underwent structural MRI for quantification of cortical thickness and surface area and diffusion tensor imaging for quantification of the quality of major fiber connections. Brain development was related to a standardized measure of cognitive control (the flanker task from the National Institutes of Health Toolbox), a critical component of self-regulation ...