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Phase-Linking And The Perceived Motion During Off-Vertical Axis Rotation, Jan E. Holly, Scott J. Wood, Gin McCollum 2009 Portland State University

Phase-Linking And The Perceived Motion During Off-Vertical Axis Rotation, Jan E. Holly, Scott J. Wood, Gin Mccollum

Gin McCollum

Human off-vertical axis rotation (OVAR) in the dark typically produces perceived motion about a cone, the amplitude of which changes as a function of frequency. This perception is commonly attributed to the fact that both the OVAR and the conical motion have a gravity vector that rotates about the subject. Little-known, however, is that this rotating-gravity explanation for perceived conical motion is inconsistent with basic observations about self-motion perception: (a) that the perceived vertical moves toward alignment with the gravito-inertial acceleration (GIA) and (b) that perceived translation arises from perceived linear acceleration, as derived from the portion of the GIA ...


Treatment Of Early And Late Kainic-Acid Induced Status Epilepticus With The Non-Competitive Ampa Receptor Antagonist Gyki 52466, Brita Fritsch, Jeffrey J. Stott, J. Joelle Donofrio, Michael A. Rogawski 2009 University of Minnesota

Treatment Of Early And Late Kainic-Acid Induced Status Epilepticus With The Non-Competitive Ampa Receptor Antagonist Gyki 52466, Brita Fritsch, Jeffrey J. Stott, J. Joelle Donofrio, Michael A. Rogawski

Michael A. Rogawski

Purpose: Benzodiazepines such as diazepam may fail to effectively treat status epilepticus because benzodiazepine-sensitive GABA-A receptors are internalized progressively with continued seizure activity. Ionotropic glutamate receptors, including AMPA receptors, are externalized, so that AMPA receptor antagonists, which are broad-spectrum anticonvulsants, could be more effective treatments for satus epilepticus. We assessed the ability of the non-competitive AMPA receptor antagonist GYKI 52466 to protect against kainic acid-induced status epilepticus in mice. Methods: Groups of animals treated with kainic acid received GYKI 52466 (50 mg/kg followed in 15 min by 50 mg/kg) or diazepam (25 mg/kg followed in 20 min ...


Neighborhood Design And Perceptions: Relationship With Active Commuting, Carolyn C. Voorhees, J. Scott Ashwood, Kelly R. Evenson, John R. Sirard, Ariane L. Rung, Marsha Dowda, Thomas L. McKenzie 2009 University of Massachusetts - Amherst

Neighborhood Design And Perceptions: Relationship With Active Commuting, Carolyn C. Voorhees, J. Scott Ashwood, Kelly R. Evenson, John R. Sirard, Ariane L. Rung, Marsha Dowda, Thomas L. Mckenzie

John Sirard

Purpose—Walking to and from school contributes to total physical activity levels. This study investigated whether perceived and actual neighborhood features were associated with walking to or from school among adolescent girls. Methods—A sample of geographically diverse 8th grade girls (N=890) from the Trial for Activity in Adolescent Girls (TAAG) study living within 1.5 miles of their middle school were recruited. Participants completed a self-administered survey on their neighborhood and walking behavior. Geographic information system (GIS) data were used to assess objective neighborhood features. Nested multivariable logistic regression analyses were conducted to determine the contribution of perceived ...


Before Creation, There Was The Big Bang, Jennifer E. Spreng, Javier M. Leija 2009 Arizona Summit Law School

Before Creation, There Was The Big Bang, Jennifer E. Spreng, Javier M. Leija

Jennifer E Spreng

No abstract provided.


Determining Rates Of Virus Production In Aquatic Systems By The Virus Reduction Approach,, M.G. Weinbauer, J.M. Rowe, Steven Wilhelm 2009 University of Tennessee, Knoxville

Determining Rates Of Virus Production In Aquatic Systems By The Virus Reduction Approach,, M.G. Weinbauer, J.M. Rowe, Steven Wilhelm

Steven Wilhelm

The reduction approach to assess virus production and the prokaryotic mortality by viral lysis stops new infection by reducing total virus abundance (and thus virus–host contacts). This allows for easy enumeration of viruses that originate from lysis of already infected cells due to the decreased abundance of free virus particles. This reoccurrence can be quantified and used to assess production and cell lysis rates. Several modifications of the method are presented and compared. The approaches have great potential for elucidating trends in virus production rates as well as for making generalized estimates of the quantitative effects of viruses on ...


Ethylene Receptors Function As Components Of High-Molecular-Mass Protein Complexes In Arabidopsis, Yi-Feng Chen, Zhiyong Gao, Robert J. Kerriss III, Wuyi Wang, Brad M. Binder, G. Eric Schaller 2009 University of Tennessee - Knoxville

Ethylene Receptors Function As Components Of High-Molecular-Mass Protein Complexes In Arabidopsis, Yi-Feng Chen, Zhiyong Gao, Robert J. Kerriss Iii, Wuyi Wang, Brad M. Binder, G. Eric Schaller

Brad M. Binder

The gaseous plant hormone ethylene is perceived in Arabidopsis thaliana by a five-member receptor family composed of ETR1, ERS1, ETR2, ERS2, and EIN4. Methodology/Principal Findings Gel-filtration analysis of ethylene receptors solubilized from Arabidopsis membranes demonstrates that the receptors exist as components of high-molecular-mass protein complexes. The ERS1 protein complex exhibits an ethylene-induced change in size consistent with ligand-mediated nucleation of protein-protein interactions. Deletion analysis supports the participation of multiple domains from ETR1 in formation of the protein complex, and also demonstrates that targeting to and retention of ETR1 at the endoplasmic reticulum only requires the first 147 amino acids ...


Anticonvulsant And Proconvulsant Actions Of 2-Deoxy-D-Glucose, Maciej Gasior, Jessica Yankura, Adam L. Hartman, Amy French, Michael A. Rogawski 2009 University of California - Davis

Anticonvulsant And Proconvulsant Actions Of 2-Deoxy-D-Glucose, Maciej Gasior, Jessica Yankura, Adam L. Hartman, Amy French, Michael A. Rogawski

Michael A. Rogawski

Purpose: 2-Deoxy-D-glucose (2-DG), a glucose analog that accumulates in cells and interferes with carbohydrate metabolism by inhibiting glycolytic enzymes, has anticonvulsant actions. Recognizing that severe glucose deprivation can induce seizures, we sought to determine whether acute treatment with 2-DG can promote seizure susceptibility by assessing its effects on seizure threshold. For comparison, we studied 3-methyl-glucose (3-MG), which like 2-DG accumulates in cells and reduces glucose uptake, but does not inhibit glycolysis. Methods: Mice were treated with 2-DG or 3-MG and the seizure threshold determined in the 6-Hz test, the mouse electroshock seizure threshold (MEST) test, and the intravenous pentylenetetrazol (i ...


Phase-Linking And The Perceived Motion During Off-Vertical Axis Rotation, Jan E. Holly, Scott J. Wood, Gin McCollum 2009 Portland State University

Phase-Linking And The Perceived Motion During Off-Vertical Axis Rotation, Jan E. Holly, Scott J. Wood, Gin Mccollum

Gin McCollum

Human off-vertical axis rotation (OVAR) in the dark typically produces perceived motion about a cone, the amplitude of which changes as a function of frequency. This perception is commonly attributed to the fact that both OVAR and the conical motion have a gravity vector that rotates about the subject. Little-known, however, is that this rotating-gravity explanation for perceived conical motion is inconsistent with basic observations about self-motion perception: (a) that the perceived vertical moves toward alignment with the gravitoinertial acceleration (GIA) and (b) that perceived translation arises from perceived linear acceleration, as derived from the portion of the GIA not ...


Ducking As The Means Of Resistance In "Candy-Cane" Stems Of Goldenrod: Straightened Stems Lose Their Edge, M. J. Wise, W. G. Abrahamson, J. A. Cole 2009 Selected Works

Ducking As The Means Of Resistance In "Candy-Cane" Stems Of Goldenrod: Straightened Stems Lose Their Edge, M. J. Wise, W. G. Abrahamson, J. A. Cole

Warren G. Abrahamson, II

Herbivores are among the most pervasive selective forces acting on plants, and the number of plant chemicals that presumably evolved for defense against herbivory is immense. In contrast, biologists are only beginning to appreciate the important roles that architectural traits can play in antiherbivore defense. One putative architectural-resistance trait is the nodding stem apex of some goldenrods (Solidago ; Asteraceae). Individuals of S. altissima genets that undergo temporary nodding in the late spring (i.e., “candy-cane ramets) have been shown to be more resistant than individuals of erect-stemmed genets to certain apex-attacking” herbivores. We tested the hypothesis that the greater resistance ...


Symmetries Of The Central Vestibular System: Forming Movements For Gravity And A Three-Dimensional World, Gin McCollum, Douglas A. Hanes 2009 Portland State University

Symmetries Of The Central Vestibular System: Forming Movements For Gravity And A Three-Dimensional World, Gin Mccollum, Douglas A. Hanes

Gin McCollum

Intrinsic dynamics of the central vestibular system (CVS) appear to be at least partly determined by the symmetries of its connections. The CVS contributes to whole-body functions such as upright balance and maintenance of gaze direction. These functions coordinate disparate senses (visual, inertial, somatosensory, auditory) and body movements (leg, trunk, head/neck, eye). They are also unified by geometric conditions. Symmetry groups have been found to structure experimentally-recorded pathways of the central vestibular system. When related to geometric conditions in three-dimensional physical space, these symmetry groups make sense as a logical foundation for sensorimotor coordination.


Ontogeny Of Digestion Defenses In Daphnia: Implications For The Effectiveness Of Algal Defenses, William R. DeMott Ph.D. 2009 Indiana University - Purdue University Fort Wayne

Ontogeny Of Digestion Defenses In Daphnia: Implications For The Effectiveness Of Algal Defenses, William R. Demott Ph.D.

William R. DeMott Ph.D.

No abstract provided.


Erau Aviation Wildlife Hazard Newsletter, Paul F. Eschenfelder 2009 Embry Riddle Aeronautical University - Daytona Beach

Erau Aviation Wildlife Hazard Newsletter, Paul F. Eschenfelder

Paul F. Eschenfelder

No abstract provided.


Laboratory Rodent Welfare: Thinking Outside The Cage, Jonathan P. Balcombe 2009 Humane Society Institute for Science and Policy

Laboratory Rodent Welfare: Thinking Outside The Cage, Jonathan P. Balcombe

Jonathan Balcombe, Ph.D.

No abstract provided.


A Brief History Of The American Fish Culture Company 1877-1997., Michael A. Rice 2009 University of Rhode Island

A Brief History Of The American Fish Culture Company 1877-1997., Michael A. Rice

Michael A Rice

The American Fish Culture Company operated for nearly 120 years from 1877-1997 in Carolina, Rhode Island growing three species of trout under the under the direction of several generations of the Hazard family of Peace Dale, Rhode Island. The company was one of the first trout producers in the United States, and was considered the largest fish farm in the country by the early 1920s. Major innovations of the company included early adoption of pelleted feeds, and the introduction of photoperiod manipulation to spawn fish out of season. The company ultimately failed due to intense competition from larger producers in ...


Nutrition As A Facilitator Of Host-Race Formation: The Role Of Food Quality In The Shift Of A Stem-Boring Beetle To A Gall Host, C. P. Blair, R. V. Schlanger, S. E. Diamond, W. G. Abrahamson 2009 Selected Works

Nutrition As A Facilitator Of Host-Race Formation: The Role Of Food Quality In The Shift Of A Stem-Boring Beetle To A Gall Host, C. P. Blair, R. V. Schlanger, S. E. Diamond, W. G. Abrahamson

Warren G. Abrahamson, II

1. The importance of host-race formation to herbivorous insect diversity depends on the likelihood that successful populations can be established on a new plant host. A previously unexplored ecological aid to success on a novel host is better nutritional quality. The role of nutrition was examined in the shift of the stem-boring beetle Mordellistena convicta to fly-induced galls on goldenrod and the establishment there of a genetically distinct gall host race. 2. First, larvae of the host race inhabiting stems of Solidago gigantea were transplanted into stems and galls of greenhouse-grown S. gigantea plants. At the end of larval development ...


Farm Focus - Spring 2010, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer 2009 University of Tennessee - Knoxville

Farm Focus - Spring 2010, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer

Brian K Whitlock, PhD, DVM, DACT

No abstract provided.


Gis @ Ut Libraries, Allison Roberts 2009 University of Tennessee - Knoxville

Gis @ Ut Libraries, Allison Roberts

Allison Roberts

Information handout/poster for GIS services at UT


Biomechanical Analysis Of Gait Adaptation In The Nematode Caenorhabditis Elegans, Christopher Fang-Yen, M Wyart, J Xie, R Kawai, S Chen, T Kodger, Q Wen, A D T Samuel 2009 Harvard University

Biomechanical Analysis Of Gait Adaptation In The Nematode Caenorhabditis Elegans, Christopher Fang-Yen, M Wyart, J Xie, R Kawai, S Chen, T Kodger, Q Wen, A D T Samuel

Christopher Fang-Yen

No abstract provided.


The Relative Influence Of Demographic, Individual, Social, And Environmental Factors On Physical Activity Among Boys And Girls, Carrie D. Patnode, Leslie A. Lytle, Darin J. Erickson, John R. Sirard, Daheia Barr-Anderson, Mary Story 2009 University of Massachusetts - Amherst

The Relative Influence Of Demographic, Individual, Social, And Environmental Factors On Physical Activity Among Boys And Girls, Carrie D. Patnode, Leslie A. Lytle, Darin J. Erickson, John R. Sirard, Daheia Barr-Anderson, Mary Story

John Sirard

Background: This study aimed to evaluate the associations of selected demographic, individual, social, and environmental factors with moderate-to-vigorous physical activity (MVPA) in a sample of children and adolescents. Methods: MVPA was assessed among youth (n = 294) 10-17-years-old using the ActiGraph accelerometer. Youth completed measures of demographic and individual variables related to physical activity (PA), perceived social support by parents and peers, and perceived neighborhood characteristics. Parents completed the long-form of the International Physical Activity Questionnaire. The Physical Activity and Media Inventory was used to measure the home environment and Geographical Information Systems software was used to measure the physical neighborhood ...


The Apoptotic Effect Of 1 ' S-1 '-Acetoxychavicol Acetate From Alpinia Conchigera On Human Cancer Cells, Noor Hasima Nagoor 2009 University of Malaya

The Apoptotic Effect Of 1 ' S-1 '-Acetoxychavicol Acetate From Alpinia Conchigera On Human Cancer Cells, Noor Hasima Nagoor

Noor Hasima Nagoor

1'-(S)-1'-Acetoxychavicol acetate (ACA) isolated from the Malaysian ethnomedicinal plant Alpinia conchigera Griff. was investigated for its potential as an anticancer drug. In this communication, we describe the cytotoxic and apoptotic properties of ACA on five human tumour cell lines. Data from MTT cell viability assays indicated that ACA induced both time-and dose-dependent cytotoxicity on all tumour cell lines tested and had no adverse cytotoxic effects on normal cells. Total mortality of the entire tumour cell population was achieved within 30 hrs when treated with ACA at 40.0 mu M concentration. Flow cytometric analysis for annexin-V and ...


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