Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

239,471 Full-Text Articles 318,401 Authors 61,040,354 Downloads 445 Institutions

All Articles in Life Sciences

Faceted Search

239,471 full-text articles. Page 5 of 6487.

Fire Resistance Of Steel Connectors Of Precast Lightweight Concrete Walls, Jen-Hao Chi, Maochieh Chi, Yue-Lin Huang 2021 epartment of Fire Science, WuFeng University, Chiayi County, Taiwan, R.O.C.

Fire Resistance Of Steel Connectors Of Precast Lightweight Concrete Walls, Jen-Hao Chi, Maochieh Chi, Yue-Lin Huang

Journal of Marine Science and Technology

In this study the fire test was performed to investigate the mechanic behaviors and failure patterns of precast normal weight concrete (NWC) and lightweight concrete (LWC) walls with three types of commonly used steel connectors, namely dry (61), wet (81), and bearing (56E) connectors. For the LWC wall specimens, on lateral application of tension, the cracking load values of the dry, wet, and bearing-type connectors were 95.1%, 86.3%, and 83.0%, respectively, of the original loads, and their ultimate load values were 81.6%, 90.7%, and 85.0%, respectively, of the original. In the shearing test after ...


Differential Evolution Algorithm For Ship Path Planning In Open Waters, Yu-Tao Kang, Wei-Jiong Chen, Jin-Hui Wang 2021 College of Ocean Science and Engineering, Shanghai Maritime University, Shanghai, China

Differential Evolution Algorithm For Ship Path Planning In Open Waters, Yu-Tao Kang, Wei-Jiong Chen, Jin-Hui Wang

Journal of Marine Science and Technology

A general approach to the derivation of simple yet accurate formulas for identifying bandpass nonlinear channels in or-thogonal frequency-division multiplexing (OFDM) systems is proposed in this paper. The OFDM is an widely adopted tech-nique for wideband communication applications. An OFDM signal could be highly vulnerable to nonlinearities in a com-munication link. This makes proper estimation of the nonlin-ear channel essential for an OFDM system. A nonlinear bandpass communication channel is commonly described by a complex Voletrra series, in which the task of nonlinear channel identification is to determine the Volterra kernels. This task can become very difficult when the order ...


Integrated Simulation Of Virtual Prototypes And Control Algorithms Of Unmanned Surface Vehicles Based On A Robot Operating System, Hye-Won Lee, Joo-Hyun Woo, Myung-Il Roh, Seung-Ho Ham, Luman Zhao, Sol Ha, Nak-Wan Kim, Chan-Woo Yu 2021 Research Institute of Marine Systems Engineering, Seoul National University, Seoul, Republic of Korea

Integrated Simulation Of Virtual Prototypes And Control Algorithms Of Unmanned Surface Vehicles Based On A Robot Operating System, Hye-Won Lee, Joo-Hyun Woo, Myung-Il Roh, Seung-Ho Ham, Luman Zhao, Sol Ha, Nak-Wan Kim, Chan-Woo Yu

Journal of Marine Science and Technology

Unmanned surface vehicles (USVs) require autonomous software with a high level of liberalization and automation to complete various missions. Therefore, experimental verification and validation of this software at the initial design stage are essential. However, such experiments are impossible before the actual hardware is developed, and the creation of an external environment for the mission requires substantial cost and time. In this study, virtual prototypes of the mission environment and hardware for the USV are developed. Then, a simulation environment for testing the control algorithms in the autonomous software is constructed. Data communication with the USV hardware is necessary for ...


Identification Of Nonlinear Channels In Bandpass Communication Systems With Ofdm Inputs, Jen-Ho Cheng, Ching-Hsiang Tseng 2021 Department of Electrical Engineering, National Taiwan Ocean University, Keelung, Taiwan, R.O.C.

Identification Of Nonlinear Channels In Bandpass Communication Systems With Ofdm Inputs, Jen-Ho Cheng, Ching-Hsiang Tseng

Journal of Marine Science and Technology

A general approach to the derivation of simple yet accurate formulas for identifying bandpass nonlinear channels in or-thogonal frequency-division multiplexing (OFDM) systems is proposed in this paper. The OFDM is an widely adopted tech-nique for wideband communication applications. An OFDM signal could be highly vulnerable to nonlinearities in a com-munication link. This makes proper estimation of the nonlin-ear channel essential for an OFDM system. A nonlinear bandpass communication channel is commonly described by a complex Voletrra series, in which the task of nonlinear channel identification is to determine the Volterra kernels. This task can become very difficult when the order ...


A Modular Open-Technology Device To Measure And Adjust Concentration Of Sperm Samples For Cryopreservation, Nikolas C. Zuchowicz 2021 Louisiana State University and Agricultural and Mechanical College

A Modular Open-Technology Device To Measure And Adjust Concentration Of Sperm Samples For Cryopreservation, Nikolas C. Zuchowicz

LSU Master's Theses

Repositories for aquatic germplasm can safeguard the genetic diversity of species of interest to aquaculture, research, and conservation. The development of such repositories is impeded by a lack of standardization both within laboratories and across the research community. Protocols for cryopreservation are often developed ad hoc and without close attention to variables, such as sperm concentration, that strongly affect the success and consistency of cryopreservation. The wide dissemination and use of specialized tools and devices can improve processing reliability, provide data logging, produce custom hardware to address unique problems, and save costs, time, and labor. The goal of the present ...


Bite Depth Penetration Patterns Of Dairy Cows Foraging On Complex Swards, W. M. Griffiths, J. Hodgson, G. C. Arnold 2021 Massey University, New Zealand

Bite Depth Penetration Patterns Of Dairy Cows Foraging On Complex Swards, W. M. Griffiths, J. Hodgson, G. C. Arnold

International Grassland Congress Proceedings

Sward height was the dominant cue used by dairy cattle to determine the depth of penetration on young vegetative swards. On more complex swards, bite depth penetration was controlled by variations in the depth of regrowth. Evidence showed that cattle grazed to the pseudostem:lamina interface, but sward height exerted a stronger effect on bite depth than pseudostem height. Modelling efforts to predict how the herbivore places bites in space in the vertical dimension across sward states are currently being restricted by the absence of detailed canopy structure descriptions. We argue that the contrast between strata is an important determinant ...


The Effect Of Progressive Grazing Of A Pasture On The Spatial Distribution Of Herbage Mass And Utilization By Cattle, Masahiko Hirata, S. Ogura 2021 University of Miyazaki, Japan

The Effect Of Progressive Grazing Of A Pasture On The Spatial Distribution Of Herbage Mass And Utilization By Cattle, Masahiko Hirata, S. Ogura

International Grassland Congress Proceedings

To develop an understanding of the spatially heterogeneous grazing of a pasture by large herbivores under progressive grazing, the herbage mass, herbage consumption and ingestive behavior by cattle were monitored daily at ninety-one 50 × 50 cm permanent locations in a bahiagrass (Paspalum notatum Flügge) pasture during a 6-day grazing period. With the progress of grazing, the mean pre-grazing herbage mass over the locations decreased. Responding to this, the mean number of visits and the mean rate of biting increased, and the mean residence time and the mean rate of defoliation decreased. The pre-grazing herbage mass became more heterogeneous, whereas the ...


Nitrogen Response Efficiencies From Grazed Dairy Pastures Under Dry Conditions, Frank R. McKenzie, J. L. Jacobs 2021 Department of Natural Resources and Environment, Australia

Nitrogen Response Efficiencies From Grazed Dairy Pastures Under Dry Conditions, Frank R. Mckenzie, J. L. Jacobs

International Grassland Congress Proceedings

Experiments were conducted within a long-term nitrogen (N) fertiliser experiment under grazing. The objective was to examine N response efficiencies (kg dry matter (DM)/kg N) and herbage crude protein (CP) content to fertiliser N applied under dry soil conditions (gravimetric soil moisture content of 17% at 10cm; soil field capacity = 38% and wilting point = 11%) during autumn (April 1999) and late spring (November 1999) in southeastern Australia. Visually, N treated plots were greener in colour than control (no N) plots. No differences were recorded in primary or residual DM yields, N response efficiencies, and pasture growth rates between N ...


Increasing Fiber Intake During Childhood And Adolescence, Madison Gunter, Stacy Bevan, Casey Coombs, Mateja R. Savoie-Roskos 2021 Utah State University

Increasing Fiber Intake During Childhood And Adolescence, Madison Gunter, Stacy Bevan, Casey Coombs, Mateja R. Savoie-Roskos

All Current Publications

Fiber is an important part of a healthful diet that provides numerous benefits when adequately consumed. Yet, many individuals do not know what fiber is, let alone how to eat enough. Thus, it is no surprise that fiber has been a dietary concern among children and adolescents for over a decade, with less than 10% of youth meeting recommended fiber intakes (Finn et al., 2019; Kranz et al., 2012; McGill et al., 2015). In this fact sheet, we will discuss what fiber is, along with its health benefits, current recommendations, and strategies for incorporating fiber into your child’s diet.


Proteoglycan-4 Is An Essential Regulator Of Synovial Macrophage Polarization And Inflammatory Macrophage Joint Infiltration, Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid 2021 Chapman University

Proteoglycan-4 Is An Essential Regulator Of Synovial Macrophage Polarization And Inflammatory Macrophage Joint Infiltration, Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid

Pharmacy Faculty Articles and Research

Background

Synovial macrophages perform a multitude of functions that include clearance of cell debris and foreign bodies, tissue immune surveillance, and resolution of inflammation. The functional diversity of macrophages is enabled by distinct subpopulations that express unique surface markers. Proteoglycan-4 (PRG4) is an important regulator of synovial hyperplasia and fibrotic remodeling, and the involvement of macrophages in PRG4’s synovial role is yet to be defined. Our objectives were to study the PRG4’s importance to macrophage homeostatic regulation in the synovium and infiltration of pro-inflammatory macrophages in acute synovitis and investigate whether macrophages mediated synovial fibrosis in Prg4 gene-trap ...


Large Scale Enzyme Based Xenobiotic Identification For Exposomics., Ken H Liu, Choon M Lee, Grant Singer, Preeti Bais, Francisco Castellanos, Michael H Woodworth, Thomas R Ziegler, Colleen S Kraft, Gary W Miller, Shuzhao Li, Young-Mi Go, Edward T Morgan, Dean P Jones 2021 The Jackson Laboratory

Large Scale Enzyme Based Xenobiotic Identification For Exposomics., Ken H Liu, Choon M Lee, Grant Singer, Preeti Bais, Francisco Castellanos, Michael H Woodworth, Thomas R Ziegler, Colleen S Kraft, Gary W Miller, Shuzhao Li, Young-Mi Go, Edward T Morgan, Dean P Jones

Faculty Research 2021

Advances in genomics have revealed many of the genetic underpinnings of human disease, but exposomics methods are currently inadequate to obtain a similar level of understanding of environmental contributions to human disease. Exposomics methods are limited by low abundance of xenobiotic metabolites and lack of authentic standards, which precludes identification using solely mass spectrometry-based criteria. Here, we develop and validate a method for enzymatic generation of xenobiotic metabolites for use with high-resolution mass spectrometry (HRMS) for chemical identification. Generated xenobiotic metabolites were used to confirm identities of respective metabolites in mice and human samples based upon accurate mass, retention time ...


Characterization Of A Fluorescent Glucose Derivative 1-Nbdg And Its Application In The Identification Of Natural Sglt1/2 Inhibitors, Ting-Yu Kao, Hwa-Wei Wu, Shoei-Sheng Lee, Pi-Hui Liang, Jih-Hwa Guh, Lih-Ching Hsu 2021 School of Pharmacy, National Taiwan University, Taipei, Taiwan

Characterization Of A Fluorescent Glucose Derivative 1-Nbdg And Its Application In The Identification Of Natural Sglt1/2 Inhibitors, Ting-Yu Kao, Hwa-Wei Wu, Shoei-Sheng Lee, Pi-Hui Liang, Jih-Hwa Guh, Lih-Ching Hsu

Journal of Food and Drug Analysis

Glucose is an important energy source for cells. Glucose transport is mediated by two types of glucose transporters: the active sodium-coupled glucose cotransporters (SGLTs), and the passive glucose transporters (GLUTs). Development of an easy way to detect glucose uptake by the cell can be valuable for research. 1-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl) amino)-1-deoxy-D-glucose (1-NBDG) is a newly synthesized fluorescent glucose analogue. Unlike 2-NBDG, which is a good substrate of GLUTs but not SGLTs, 1-NBDG can be transported by both GLUTs and SGLTs. Thus, 1-NBDG is useful for the screening of SGLT1 and SGLT2 inhibitors. Here we further characterized 1-NBDG and ...


Lucigenin-Pyrogallol Chemiluminescence For The Multiple Detection Of Pyrogallol, Cobalt Ion, And Tyrosinase, Islam M. Mostafa, Muhammad Rehan Hasan Shah Gilani, Yequan Chen, Baohua Lou, Jianping Li, Guobao Xu 2021 State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences,Changchun, Jilin, PR China

Lucigenin-Pyrogallol Chemiluminescence For The Multiple Detection Of Pyrogallol, Cobalt Ion, And Tyrosinase, Islam M. Mostafa, Muhammad Rehan Hasan Shah Gilani, Yequan Chen, Baohua Lou, Jianping Li, Guobao Xu

Journal of Food and Drug Analysis

Developing new, cheap, sensitive and selective chemiluminescence (CL) systems with multiple detection properties is still a big challenge for biological and environmental applications. Here, we report a new CL system having multiple detection applications (environmental and biological). The developed lucigenin-pyrogallol system gave an enhancement (190 times) over the conventional lucigenin-H2O2 CL system. Cobalt ion and tyrosinase can inhibit lucigenin-PG CL intensity. Based on these phenomena, we have developed new CL methods for the detection of pyrogallol (LOD = 0.94 μM), lucigenin (LOD = 0.42 μM), cobalt (LOD = 68 μM), and tyrosinase (LOD = 1.8 μg/mL). Furthermore ...


Determination Of Cannabinoids In Hemp Oil Based Cosmetic Products By Lc-Tandem Ms, Yun-Hua Hsu, Ming-Chih Fang, Shou-Chieh Huang, Ya-Min Kao, Su-Hsiang Tseng, Der-Yuan Wang 2021 Food and Drug Administration, Ministry of Health and Welfare, Taipei, Taiwan

Determination Of Cannabinoids In Hemp Oil Based Cosmetic Products By Lc-Tandem Ms, Yun-Hua Hsu, Ming-Chih Fang, Shou-Chieh Huang, Ya-Min Kao, Su-Hsiang Tseng, Der-Yuan Wang

Journal of Food and Drug Analysis

Cosmetic products containing hemp seed oil as permitted raw materials required the specific compound delta-9-tetrahydrocannabinol (THC) below 10 µg/g. THC was the main psychoactive constituent of cannabis. Since hemp seed oil became an increasingly popular ingredient in cosmetics over the last few years, an efficient and reliable analytical method for THC and other cannabinoids in cannabis-infused cosmetic products was in need. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of delta-9-tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabinol (CBN) in hemp seed oil based cosmetic products was developed. Method validation was performed by fertilizing blank samples with analytes ...


Comprehensive Multiplexed Analysis Of Risky Drugs In Eggs Based On Magnetic Zeolitic Imidazolate Frameworks And Uhplc Q-Orbitrap Hrms, Wei Jia, Yuyang Liu, Xi Xu, Yanxi Zhang, Lin Shi 2021 Shaanxi University of Science and Technology, China

Comprehensive Multiplexed Analysis Of Risky Drugs In Eggs Based On Magnetic Zeolitic Imidazolate Frameworks And Uhplc Q-Orbitrap Hrms, Wei Jia, Yuyang Liu, Xi Xu, Yanxi Zhang, Lin Shi

Journal of Food and Drug Analysis

A novel magnetic adsorbent solid-phase Fe3O4@ZIF-8 extraction method coupled with UHPLC Q-Orbitrap high resolution mass spectrometry for the sensitive and high efficiency detection of fluoroquinolones, tetracyclines, dyes and amphenicols in eggs is described. Under optimum conditions, CCβ and CCα of 0.62 to 26.97 μg.kg1 and 0.36 to 16.37 μg.kg1 was obtained, which is much better than that obtained by conventional methods. The accuracy, expressed as recovery, were achieved falling between 75% and 104%. The proposed strategy provides several advantages of simplicity and low energy consumption, thus retaining potential ...


An Extractive Nanoelectrospray Ionization-Mass Spectrometry Method For Chinese Herbal Medicine Authentication, Chia-Hsin Lee, Hui-Chi Huang, Mei-Chun Tseng, Chao-Jung Chen 2021 Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan

An Extractive Nanoelectrospray Ionization-Mass Spectrometry Method For Chinese Herbal Medicine Authentication, Chia-Hsin Lee, Hui-Chi Huang, Mei-Chun Tseng, Chao-Jung Chen

Journal of Food and Drug Analysis

Herein, we describe a rapid, sensitive, and nondestructive method—extractive nanoelectrospray ionization-mass spectrometry (EnESI-MS)—for traditional Chinese medicine (TCM) authentication. The mass-spectral fingerprints of volatile compounds released from various TCMs can be rapidly acquired using EnESI-MS without sample pretreatment. EnESI-MS was applied to successfully differentiate between two commonly used medicinal herbs, Schisandra Chinensis and Schisandra sphenanthera, which are morphologically similar but exhibit different therapeutic effects. Specific volatile compounds of each herb in a ten-component Chinese herbal product, Jia Wei Xiao Yao San, were also identified, and the method was applied to discriminate between the commercial product and a substandard version.


Mesonosides A-H, Primeverose Derivatives From Mesona Procumbens Suppress Adipogenesis By Downregulating Pparg And C/Ebpa In 3t3-L1 Cells, Hung-Tse Huang, Chia-Ching Liaw, Chun-Tang Chiou, Kung-Ta Lee, Yao-Haur Kuo 2021 Division of Chinese Materia Medica Development, National Research Institute of Chinese Medicine, Taipei, Taiwan

Mesonosides A-H, Primeverose Derivatives From Mesona Procumbens Suppress Adipogenesis By Downregulating Pparg And C/Ebpa In 3t3-L1 Cells, Hung-Tse Huang, Chia-Ching Liaw, Chun-Tang Chiou, Kung-Ta Lee, Yao-Haur Kuo

Journal of Food and Drug Analysis

Obesity is becoming a worldwide epidemic, especially in industrialized countries. We hereby report a methanolic extract of Mesona procumbens (known as Hsian-tsao in Taiwan) significantly inhibits lipid accumulation in 3T3-L1 adipocytes, and eight new primeverose derivatives, mesonosides A-H (1-8), were isolated from the methanolic extract of M. procumbens. Structural elucidation of 1-8 was established by spectroscopic methods, especially 2D NMR techniques (1H-1H COSY, HSQC, HMBC, and NOESY) and HRESIMS. Anti-obesity evaluation revealed that isolates 1-5, 7, and 8 showed inhibitory effects on lipid accumulation and protein levels of adipogenic transcription factor, PPARγ and C/EBPa in 3T3-L1 ...


Induction Of Mitochondrial-Dependent Apoptosis By Essential Oil Of Toona Sinensis Root Through Akt, Mtor And Nf-Κb Signalling Pathways In Human Renal Cell Carcinoma Cells, Yu-Chi Chen, Chiao-Ling Hsieh, Bu-Miin Huang, YungChia Chen 2021 Department of Urology, E-Da Cancer Hospital, Kaohsiung, Taiwan

Induction Of Mitochondrial-Dependent Apoptosis By Essential Oil Of Toona Sinensis Root Through Akt, Mtor And Nf-Κb Signalling Pathways In Human Renal Cell Carcinoma Cells, Yu-Chi Chen, Chiao-Ling Hsieh, Bu-Miin Huang, Yungchia Chen

Journal of Food and Drug Analysis

Natural products have long been considered as a kind of complementary medicine. In this study, we investigate the apoptotic effect of essential oils of Toona sinensis roots (TSR) on human clear cell renal cell carcinomas (ccRCC). The sesquiterpene content of TSR essential oil was determined via GC/MS analysis. TSR decreased ccRCC cell viabilities, inducing ROS generation and reduction of the mitochondrial membrane potential. Moreover, TSR inhibited Bcl-2 and Hsp90 expression but increased PARP-1 cleavage and cytochrome c release. Akt, mTOR and NF-kB phosphorylation and HIF-a expression were all inhibited, which likely contributed to the anti-proliferative and anti-adhesive effects of ...


Comprehensive Detection Of 120 Additives In Food Using Nontargeted Ms Data Acquisition, Che-Lun Hsu, Mingchih Fang, Hui-Chun Tseng, Ya-Tze Lin, Su-Hsiang Tseng, Der-Yuan Wang, Deng-Fwu Hwang 2021 Department of Food Science, National Taiwan Ocean University, Keelung City, Taiwan

Comprehensive Detection Of 120 Additives In Food Using Nontargeted Ms Data Acquisition, Che-Lun Hsu, Mingchih Fang, Hui-Chun Tseng, Ya-Tze Lin, Su-Hsiang Tseng, Der-Yuan Wang, Deng-Fwu Hwang

Journal of Food and Drug Analysis

The compliance assessment on the labeling of food additives is a hard job, because there are nearly thousand legal food additives can be used in food, and countless illegal additives must also deal with. This study developed a nontargeted data acquisition screening method based on liquid chromatography high resolution mass spectrometry (HRMS) in which a precursor ion and two product ions of each analyte are able to be recorded. The high throughput screening method worked as foodomics that characterized and identified every food components as long as they were ionized in terms of theory. The data acquisition method called data ...


Transcriptome Analysis Of Lactobacillus Rhamnosus Gg Strain Treated With Prebiotic - Bovine Lactoferrin Under A Cold Environment, Zhen-Shu Liu, Chuen-Fu Lin, Po-Wen Chen 2021 Department of Safety, Health and Environmental Engineering, Ming Chi University of Technology, New Taipei City, Taiwan

Transcriptome Analysis Of Lactobacillus Rhamnosus Gg Strain Treated With Prebiotic - Bovine Lactoferrin Under A Cold Environment, Zhen-Shu Liu, Chuen-Fu Lin, Po-Wen Chen

Journal of Food and Drug Analysis

Lactoferrin (LF) is secreted by mammals and displays extensive biological effects. We previously reported that bovine LF (BLF) can boost the cold tolerance of a well-applied probiotic strain, Lactobacillus rhamnosus GG (LGG), to grow robustly under a cold environment, but the molecular mechanism is not clear. Here, RNA-seq analysis was conducted to ascertain molecular pathways underlying cold tolerance exerted by BLF. LGG was cultured in a cold environment (22°C) in the presence or absence of BLF. Transcriptome analysis indicated that BLF significantly elicited 1.2 to 3.2 fold (log2 Fold change) higher expression levels of genes related to ...


Digital Commons powered by bepress