The Contribution Of Local And Transport Processes To Phytoplankton Biomass Variability Over Different Timescales In The Upper James River, Virginia, 2018 Virginia Institute of Marine Science
The Contribution Of Local And Transport Processes To Phytoplankton Biomass Variability Over Different Timescales In The Upper James River, Virginia, Qubin Qin, Jian Shen
Although both local processes (photosynthesis, respiration, grazing, and settling), and transport processes (advective transport and diffusive transport) significantly affect local phytoplankton dynamics, it is difficult to separate their contributions and to investigate the relative importance of each process to the local variability of phytoplankton biomass over different timescales. A method of using the transport rate is introduced to quantify the contribution of transport processes. By combining the time-varying transport rate and high-frequency observed chlorophyll a data, we can explicitly examine the impact of local and transport processes on phytoplankton biomass over a range of timescales from hourly to annually. For ...
The Manuscript Works Of S. Fred Prince (1857-1951), 2018 University of Dayton
The Manuscript Works Of S. Fred Prince (1857-1951), Sarah Burke Cahalan, Jason W. Dean
Marian Library/IMRI Faculty Publications
S. Fred Prince, a botanical illustrator and amateur scientist, is a largely unknown artist whose work on the American landscape demonstrates his eligibility to be considered in the lineage of self-taught illustrator-naturalists such as Mark Catesby and Genevieve Jones. In this article, we present a survey of extant Prince materials identified at time of writing, describing their contents and physical characteristics. Beyond this survey and description, we also provide a biographical sketch and timeline of Prince's life.
Altering Oligomerization Of Epha2 Via Mutations In The Intracellular Domain, 2018 The University of Akron
Altering Oligomerization Of Epha2 Via Mutations In The Intracellular Domain, Ryan W. Lingerak
Honors Research Projects
Eph receptor tyrosine kinases (RTKs) are activated by membrane-bound ligands called ephrins. Eph RTKs are divided into two subclasses, each activated by a specific classes of the ligand ephrin. The overexpression of Eph receptors is correlated to cancer cell metastasis in several different types of cancers. Studies with the EphA2 extracellular domain (ECD) and ephrinA1 ligand have shown that upon binding of ephrin to the receptor, EphA2 undergoes increased oligomerization and activation. This indicates that oligomerization is intimately connected to kinase activity. High resolution crystal structures of the EphA2 ECD have revealed some details of these ligand bound oligomers, as ...
Potential For Climate Induced Methane Hydrate Dissociation, 2018 Pomona College
Potential For Climate Induced Methane Hydrate Dissociation, Graham Macwilliams
Pomona Senior Theses
Methane hydrates are frozen deposits of methane and water found in high pressure or low temperature sediments. When these deposits destabilize, large quantities of methane can be emitted into the atmosphere. This is significant to climate change because methane has 25 times more greenhouse gas potential than Carbon Dioxide. Worldwide, it is estimated there are between 2500 and 10000 gigatons of methane stored in hydrate deposits. This represents more carbon than all fossil fuels on Earth. It is estimated that between 200 and 2000 gigatons of methane are stored in hydrates in Arctic waters acutely vulnerable to greenhouse warming. Over ...
Tea Induction Of Cyp6a8 Promoter In Drosophila Melanogaster, 2017 University of Tennessee, Knoxville
Tea Induction Of Cyp6a8 Promoter In Drosophila Melanogaster, Fiona Retzer
University of Tennessee Honors Thesis Projects
No abstract provided.
The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, 2017 Dominican University of California
The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, Kimberly Kelsey
Senior Theses and Capstone Projects
Type 1 Diabetics have various ways of managing their diabetes that have been studied for their effectiveness. Pregnancy in the Type 1 Diabetic has been understudied. It is known that Diabetics in general have poorer pregnancy outcomes because of poor glycemic control. This coupled with the fact that the body needs 3-4 times more insulin as pregnancy comes to an end makes managing blood glucose levels challenging for diabetics (Lowdermilk, 2016, p. 689). For the Type 1 Diabetic, there are two main ways to control diabetes: multiple daily injections using at least two type of insulin and continuous subcutaneous insulin ...
Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential For Endoplasmic Reticulum To Outer Mitochondrial Membrane Protein Transport., 2017 George Washington University
Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential For Endoplasmic Reticulum To Outer Mitochondrial Membrane Protein Transport., Kyle Salka, Shivaprasad Bhuvanendran, Kassandra Wilson, Petros Bozidis, Mansi Mehta, Kristin Rainey, Hiromi Sesaki, George H Patterson, Jyoti K. Jaiswal, Anamaris M. Colberg-Poley
Genomics and Precision Medicine Faculty Publications
Most nuclear-encoded mitochondrial proteins traffic from the cytosol to mitochondria. Some of these proteins localize at mitochondria-associated membranes (MAM), where mitochondria are closely apposed with the endoplasmic reticulum (ER). We have previously shown that the human cytomegalovirus signal-anchored protein known as viral mitochondria-localized inhibitor of apoptosis (vMIA) traffics from the ER to mitochondria and clusters at the outer mitochondrial membrane (OMM). Here, we have examined the host pathways by which vMIA traffics from the ER to mitochondria and clusters at the OMM. By disruption of phosphofurin acidic cluster sorting protein 2 (PACS-2), mitofusins (Mfn1/2), and dynamin related protein 1 ...
Plasma Fibroblast Growth Factor-21 Levels In Patients With Inborn Errors Of Metabolism, 2017 George Washington University
Plasma Fibroblast Growth Factor-21 Levels In Patients With Inborn Errors Of Metabolism, Brian Kirmse, Juan Cabrera-Luque, Omar Ayyub, Kristina Cusmano-Ozog, Kimberly A. Chapman, Marshall L. Summar
Pediatrics Faculty Publications
Fibroblast growth factor-21 (FGF21) levels are elevated in patients with primary mitochondrial disorders but have not been studied in patients with inborn errors of metabolism (IEM) known to have secondary mitochondrial dysfunction. We measured plasma FGF21 by ELISA in patients with and without IEM. FGF21 levels were higher in patients with IEM compared to without IEM (370 pg/dL vs. 0–65 pg/dL). Further study of FGF21 as a biomarker in IEM is warranted.
Characterisation Of Cold Plasma Treated Beef And Dairy Lipids Using Spectroscopic And Chromatographic Methods, 2017 Dublin Institute of Technology
Characterisation Of Cold Plasma Treated Beef And Dairy Lipids Using Spectroscopic And Chromatographic Methods, Chaitanya Sarangapani, David Dorran, Julie Dunne, Paula Bourke, Patrick Cullen
The efficacy of cold plasma for inactivation of food-borne pathogens in foods is established. However, insights on cold plasma-food interactions in terms of quality effects, particularly for oils and fats, are sparse. This study evaluated plasma-induced lipid oxidation of model matrices, namely dairy and meat fats. Product characterisation was performed using FTIR, 1H NMR and chromatographic techniques. The oxidation of lipids by cold plasma followed the Criegee mechanism and typical oxidation products identified included ozonides, aldehydes (hexanal, pentenal, nonanal and nonenal) and carboxylic acids (9-oxononanoic acid, octanoic acid, nonanoic acid), along with hydroperoxides (9- and 13-hydroperoxy-octadecadienoylglycerol species). However, these ...
Endothelial Cells, 2017 Selected Works
Endothelial Cells, Bennie Liu
Building Academic/Practitioner Teams For Human Rights Projects: Examples, Lessons Learned, And Pitfalls To Avoid, 2017 American Association for the Advancement of Science
Building Academic/Practitioner Teams For Human Rights Projects: Examples, Lessons Learned, And Pitfalls To Avoid, Theresa Harris
The Social Practice of Human Rights: Charting the Frontiers of Research and Advocacy
Academics are increasingly interested in getting out of their classrooms and labs to contribute their knowledge, expertise, and resources to help communities develop evidence-based policies. In addition to post-election initiatives such as the March for Science and 314 Action, many academics are joining “without borders”-type programs and organizations that connect academics with opportunities to volunteer their time and talents for “social good.”
One of the longest-running of these is On-call Scientists, an initiative of the American Association for the Advancement of Science (AAAS) that connects human rights organizations with pro bono scientists across all fields — life, physical, behavioral, and ...
Characterization Of A Novel Mitochondrial Plasmid In Brassica, 2017 University of Nebraska - Lincoln
Characterization Of A Novel Mitochondrial Plasmid In Brassica, Mackenzie Strehle
UCARE Research Products
Possessing some of the largest and most complex genomes of any eukaryotic organelles, plant mitochondria are notorious for their rapidly rearranging genetic framework. In addition to containing a large and complex mitochondrial genome, the mitochondria of several plants in the genus Brassica have also been shown to contain an independent, self-replicating linear plasmid. Interestingly, the plasmid appears to be able to move independently between the cytoplasm and the mitochondria, and it can be paternally inherited, unlike the rest of the mitochondrial genome. The plasmid also has features similar to those of adenoviruses, including terminal inverted repeats and covalently bound proteins ...
Farm-Scale Testing Of Soybean Peroxidase And Calcium Peroxide For Surficial Swine Manure Treatment And Mitigation Of Odorous Vocs, Ammonia And Hydrogen Sulfide Emissions, Devin L. Maurer, Jacek A. Koziel, Kelsey Bruning, David B. Parker
Agricultural and Biosystems Engineering Publications
The swine industry, regulatory agencies, and the public are interested in farm-tested methods for controlling gaseous emissions from swine barns. In earlier lab- and pilot-scale studies, a renewable catalyst consisting of soybean peroxidase (SBP) mixed with calcium peroxide (CaO2) was found to be effective in mitigating gaseous emissions from swine manure. Thus, a farm-scale experiment was conducted at the university's 178-pig, shallow-pit, mechanically-ventilated swine barn to evaluate SBP/CaO2 as a surficial manure pit additive under field conditions. The SBP was applied once at the beginning of the 42-day experiment at an application rate of 2.28 ...
Direct Antioxidant Properties Of Methotrexate: Inhibition Of Malondialdehyde-Acetaldehyde-Protein Adduct Formation And Superoxide Scavenging., 2017 University of Nebraska Medical Center
Direct Antioxidant Properties Of Methotrexate: Inhibition Of Malondialdehyde-Acetaldehyde-Protein Adduct Formation And Superoxide Scavenging., Matthew C. Zimmerman, Dahn L. Clemens, Michael J. Duryee, Cleofes Sarmiento, Andrew Chiou, Carlos D. Hunter, Jun Tian, Lynell W. Klassen, James R. O'Dell, Geoffrey M. Thiele, Ted R. Mikuls, Daniel R. Anderson
Journal Articles: Cellular & Integrative Physiology
Methotrexate (MTX) is an immunosuppressant commonly used for the treatment of autoimmune diseases. Recent observations have shown that patients treated with MTX also exhibit a reduced risk for the development of cardiovascular disease (CVD). Although MTX reduces systemic inflammation and tissue damage, the mechanisms by which MTX exerts these beneficial effects are not entirely known. We have previously demonstrated that protein adducts formed by the interaction of malondialdehyde (MDA) and acetaldehyde (AA), known as MAA-protein adducts, are present in diseased tissues of individuals with rheumatoid arthritis (RA) or CVD. In previously reported studies, MAA-adducts were shown to be highly immunogenic ...
Gamma Sigma Delta, Nebraska Chapter Newsletter, Issue #55 Fall 2017, 2017 University of Nebraska - Lincoln
Gamma Sigma Delta, Nebraska Chapter Newsletter, Issue #55 Fall 2017
Gamma Sigma Delta, Nebraska Chapter, Newsletters
The Nebraska Chapter was selected as a Gold Chapter for the second consecutive year. The Gold Chapter Achievement Award is selected based on the annual chapter report. A maximum of five chapters may receive the award each year.
President’s Message, Dann Husmann
2017 Gamma Sigma Delta International Foundation Undergraduate Scholarship - Alissa Martindale
2017 John Riley Gamma Sigma Delta Service Scholarship - Andrea Gurney
In Memoriam: Albert “Dale” Flowerday, 89; Michael G. Boosalis, 99; Loyd Karl Fischer, 97
NOMINATIONS FOR GAMMA SIGMA DELTA – Due November 17, 2017
Award of Merit Nomination
Extension Award Nomination
Research Award Nomination
Teaching Award Nomination
Pertinacity Volume 3 Issue 2, 2017 University of Connecticut - Storrs
Pertinacity Volume 3 Issue 2, Yuri Hosokawa
No abstract provided.
Pertinacity Volume 3 Issue 1, 2017 University of Connecticut - Storrs
Pertinacity Volume 3 Issue 1, Yuri Hosokawa
No abstract provided.
Regulation Of The Amyloid Precursor Protein By Prostaglandin J2, A Mediator Of Inflammation: Relevance To Alzheimer’S Disease, 2017 The Graduate Center, City University of New York
Regulation Of The Amyloid Precursor Protein By Prostaglandin J2, A Mediator Of Inflammation: Relevance To Alzheimer’S Disease, Teneka L. Jean-Louis
All Graduate Works by Year: Dissertations, Theses, and Capstone Projects
Inflammation plays a major role in Alzheimer’s disease (AD). Investigating how specific mediators of inflammation contribute to neurodegeneration in AD is crucial. Our studies focused on cyclooxygenases, which are key enzymes in inflammation and highly relevant to AD. Cyclooxygenases (COX -1, constitutive; COX-2, inducible) have emerged as important determinants of AD pathogenesis and progression. COX-2 is highly induced in AD, correlating with AD severity, and COX-1 is also involved in AD. Cyclooxygenases are the rate-limiting enzymes that convert arachidonic acid into prostaglandins (PGs), the principal mediators of CNS neuroinflammation.
The overall GOAL of these studies was to address the ...
The Role Of Glutamate Neurotransmission In The Ventral Tegmental Area In The Expression Of Conditioned Approach Learning, 2017 The Graduate Center, City University of New York
The Role Of Glutamate Neurotransmission In The Ventral Tegmental Area In The Expression Of Conditioned Approach Learning, Priscila Hachimine-Merli
All Graduate Works by Year: Dissertations, Theses, and Capstone Projects
Conditioned stimuli (CSs) come to function as CSs by acquiring the capacity to activate the same mesocorticolimbic dopamine (DA) neurons activated by primary rewards, producing conditioned activation of these neurons and their associated motivational states. This model stipulates that CSs activate mesocorticolimbic DA systems through the activation of glutamate receptors on DA neurons in the ventral tegmental area (VTA). We tested the hypothesis that glutamate receptor stimulation in the VTA is necessary for the expression of conditioned approach. Rats were tested in a conditioned approach protocol that consisted of 7 consecutive conditioning sessions (light presentations and food were paired), one ...
Tracking 19th Century Late Blight From Archival Documents Using Text Analytics And Geoparsing, 2017 NC State University Center For Geospatial Analytics
Tracking 19th Century Late Blight From Archival Documents Using Text Analytics And Geoparsing, Laura Tateosian, Rachael Guenter, Yi-Peng Yang, Jean Ristaino
Free and Open Source Software for Geospatial (FOSS4G) Conference Proceedings
In 1845, Ireland's potato crop was struck by a devastating potato disease that killed Ireland’s crop caused devastation for seven years and led to mass starvation and emigration from the country. The cause of the potato destruction was a fungus-like plant pathogen. There are several theories about the origin of the disease and the source of the 19th century outbreaks. We use historical documents contemporary to that time to investigate spatial information that might inform these mysteries. We present methodologies for automatically extracting information from these voluminous data sources. We identify and map geographic locations that are proximate ...