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Screening And Assessment Of Cancer-Related Fatigue: An Executive Summary And Road Map For Clinical Implementation, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone, Mary I. Fisher 2022 University of South Carolina

Screening And Assessment Of Cancer-Related Fatigue: An Executive Summary And Road Map For Clinical Implementation, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone, Mary I. Fisher

Physical Therapy Faculty Publications

Background: Cancer-related fatigue (CRF) prevalence is reported as high as 90%. Cancer-related fatigue is multidimensional and associated with lower health-related quality of life. Effective screening and assessment are dependent upon use of valid, reliable, and clinically feasible measures. This Executive Summary of the Screening and Assessment of Cancer-related Fatigue Clinical Practice Guideline provides recommendations for best measures to screen and assess for CRF based on the quality and level of evidence, psychometric strength of the tools, and clinical utility.

Methods: After a systematic review of the literature, studies evaluating CRF measurement tools were assessed for quality; data extraction included psychometrics …


Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farah Fallahtafti, Mohammad Ali Takallou, Hafizur Rahman, Basheer Qolomany, Iraklis Pipinos, Fadi Alsaleem, Sara A. Myers 2022 University of Nebraska at Omaha

Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farah Fallahtafti, Mohammad Ali Takallou, Hafizur Rahman, Basheer Qolomany, Iraklis Pipinos, Fadi Alsaleem, Sara A. Myers

Journal Articles

Peripheral artery disease (PAD) manifests from atherosclerosis, which limits blood flow to the legs and causes changes in muscle structure and function, and in gait performance. PAD is underdiagnosed, which delays treatment and worsens clinical outcomes. To overcome this challenge, the purpose of this study is to develop machine learning (ML) models that distinguish individuals with and without PAD. This is the first step to using ML to identify those with PAD risk early. We built ML models based on previously acquired overground walking biomechanics data from patients with PAD and healthy controls. Gait signatures were characterized using ankle, knee, …


Co-Twin Relationship Quality As A Moderator Of Genetic And Environmental Factors On Urinary Cortisol Levels Among Adult Twins, Joseph A. Schwartz, Scott Jessick, Jessica L. Calvi, Douglas A. Granger 2022 University of Nebraska-Lincoln

Co-Twin Relationship Quality As A Moderator Of Genetic And Environmental Factors On Urinary Cortisol Levels Among Adult Twins, Joseph A. Schwartz, Scott Jessick, Jessica L. Calvi, Douglas A. Granger

Athletic Performance Research

Previous research has indicated that genetic and environmental factors shape physiological activity. Cortisol levels, in particular, have received significant attention, with studies indicating substantive heritability estimates across various sampling techniques. A related line of research has indicated that genetic and environmental factors that explain variability in cortisol levels may vary across context and experiences by way of gene-environment interactions (G×Es). Despite these findings, a limited number of studies have examined the extent to which interpersonal relationships may operate as a moderator. The current study focused on co-twin relationship quality as a source of moderation, as twins are more likely to …


Advancing The Assessment And Treatment Of Signs And Symptoms Of Parkinson Disease, David Scott May 2022 Washington University School of Medicine in St. Louis

Advancing The Assessment And Treatment Of Signs And Symptoms Of Parkinson Disease, David Scott May

WUSM Theses and Dissertations – All Programs

People with PD often report signs and symptoms that negatively impact quality of life. Among these are balance difficulties, impaired gait, and FOG. New treatment and assessment strategies for these signs and symptoms are needed, as current techniques are limited. While new treatment and assessment strategies continue to emerge, gaps in knowledge persist. Deep brain stimulation (DBS) has been utilized in many people with PD throughout the 21st century, but it is unknown specifically how subthalamic nucleus deep brain stimulation (STN-DBS) affects balance. Alternative treatment strategies, such as a dental mouthpiece, have also been proposed. While dental mouthpieces have shown …


Modeling, Analysis, And Simulation To Reveal The Mechanisms Of Ciliary Beating, Louis Woodhams 2022 Washington University in St. Louis

Modeling, Analysis, And Simulation To Reveal The Mechanisms Of Ciliary Beating, Louis Woodhams

McKelvey School of Engineering Theses & Dissertations

Cilia are microscopic cellular appendages that help us breathe by clearing our airways, maintain the health of our central nervous system by circulating cerebrospinal fluid, and allow us to reproduce by transporting eggs and propelling sperm cells. Cilia even determine the asymmetry of our internal organs during embryonic development. However, the mechanisms underlying ciliary beating are not fully understood. Questions remain as to how arrays of the motor protein dynein generate the propulsive waveforms observed in cilia and how structural elements within the cilium and its connection to the cell deform during beating. In the current work, mathematical modeling, analysis, …


A Biomechanical Approach To Prevent Falls In Ergonomic Settings, Sachini Kodithuwakku Arachchige 2022 Mississippi State University

A Biomechanical Approach To Prevent Falls In Ergonomic Settings, Sachini Kodithuwakku Arachchige

Theses and Dissertations

Introduction: Fall-related injuries are exceptionally prevalent in occupational settings. While endangering the workers’ health, falls cause poor productivity and increased economic burden in the workplace. Hence, identifying these threats and training workers to achieve proper postural control is crucial. Purpose: Study 1: To investigate the ankle joint kinematics in unexpected and expected trip responses during single-tasking (ST), dual-tasking (DT), and triple-tasking (TT), before and after a physically fatiguing exercise. Study 2: To investigate the impact of virtual heights, DT, and training on static postural stability and cognitive processing. Methods: Study 1: Twenty collegiate volunteers (10 males and females, one left …


Contributions Of Vision To The Neuromotor Control And Biomechanics Of Depth Jumping, Kenneth Harrison 2022 Utah State University

Contributions Of Vision To The Neuromotor Control And Biomechanics Of Depth Jumping, Kenneth Harrison

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

PURPOSE: To investigate the role of vision during depth jump movements and further explore effects of stroboscopic goggles on the motor control of landing. METHODS: Ground reaction force (GRF), rate of force development (RFD), and lower limb surface electromyography measurements were collected on 20 participants (11 male 9 female) across 6 trials of depth jumping (0.51 m) in each of two visual conditions (full vision vs stroboscopic vision). Root-mean-square was estimated from EMG signals that were reduced to specific time-bins (150ms pre touchdown, 30-60ms, 60-85 ms, and 85-120 ms post touchdown). Main effects of and interactions between visual condition and …


The Effects Of Cheerleading Surfaces On Landing Characteristics During Vertical And Flip Landings, Anthony Vu Nguyen 2022 University of Wisconsin-Milwaukee

The Effects Of Cheerleading Surfaces On Landing Characteristics During Vertical And Flip Landings, Anthony Vu Nguyen

Theses and Dissertations

Lateral ankle sprains are common injuries in cheerleading and typically occurring during tumbling. The landing surface can impact injury risk by modulating loading parameters and risky joint positions. Most surface-landing studies have used vertical landing tasks to study acrobatic populations, and few studies have compared vertical and flipping tasks. Therefore, the purpose of this study was to compare the effects of two cheerleading surfaces between vertical drop landing and flip landing tasks. Doing so explained surface characteristic influences on landing and the validity of using vertical landing tasks to represent acrobatic sports. Twelve collegiate cheerleaders (7 females, 5 males; age: …


Sex Differences In Cancer Cachexia And A Novel Mitochondrial Target For Cancer-Induced Muscle Wasting, Seongkyun Lim 2022 University of Arkansas, Fayetteville

Sex Differences In Cancer Cachexia And A Novel Mitochondrial Target For Cancer-Induced Muscle Wasting, Seongkyun Lim

Graduate Theses and Dissertations

Cancer cachexia (CC) is a devastating wasting syndrome characterized by marked weight loss including skeletal muscle atrophy that affects approximately 80% of cancer patients. Current therapeutic treatments including pharmacological and nutritional intervention are insufficient to prevent or reverse it. Prior studies demonstrated lower muscle mass, impaired muscle function, and mitochondrial health in the development of CC. Specifically, mitochondrial fusion protein, Optic atrophy 1 (OPA1) which plays a significant role in skeletal muscle health, is suppressed in the development of CC. Furthermore, most pre-clinical CC studies were mainly focused on males although there are distinct phenotypical differences in skeletal muscle between …


Utilization Of Finite Element Analysis Techniques For Adolescent Idiopathic Scoliosis Surgical Planning, Michael A. Polanco 2022 Old Dominion University

Utilization Of Finite Element Analysis Techniques For Adolescent Idiopathic Scoliosis Surgical Planning, Michael A. Polanco

Mechanical & Aerospace Engineering Theses & Dissertations

Adolescent Idiopathic Scoliosis, a three-dimensional deformity of the thoracolumbar spine, affects approximately 1-3% of patients ages 10-18. Surgical correction and treatment of the spinal column is a costly and high-risk task that is consistently complicated by factors such as patient-specific spinal deformities, curve flexibility, and surgeon experience. The following dissertation utilizes finite element analysis to develop a cost-effective, building-block approach by which surgical procedures and kinematic evaluations may be investigated. All studies conducted are based off a volumetric, thoracolumbar finite element (FE) model developed from computer-aided design (CAD) anatomy whose components are kinematically validated with in-vitro data. Spinal ligament stiffness …


Balance Recovery Response In Community-Dwelling Adults With Unilateral Transtibial Amputation And The Potential Benefits Of A Weight-Shifting Balance Training Intervention, Hui-Ting Shih 2022 University of Nevada, Las Vegas

Balance Recovery Response In Community-Dwelling Adults With Unilateral Transtibial Amputation And The Potential Benefits Of A Weight-Shifting Balance Training Intervention, Hui-Ting Shih

UNLV Theses, Dissertations, Professional Papers, and Capstones

Previous studies have shown that individuals with various physical, sensory and neuromuscular impairments are at higher risks of falls. Individuals with unilateral transtibial amputation (UTTA) suffered from all these impairments, and tripping not surprisingly caused a considerable number of falls in this population. To study falls, researchers have to put participants in a well-protected environment and reproduce tripping fall scenarios. Furthermore, the perturbation delivery needs to be precise in terms of temporo-spatial timing. These features would ensure the quality of responses elicited and reproducibility of the results. Thus, in Chapter 2, we developed a treadmill-based perturbation delivery protocol and confirmed …


Slamming Dynamics Of Diving And Its Implications For Diving-Related Injuries, Anupam Pandey, Jisoo Yuk, Brian Chang, Frank E. Fish, Sunghwan Jung 2022 Cornell University

Slamming Dynamics Of Diving And Its Implications For Diving-Related Injuries, Anupam Pandey, Jisoo Yuk, Brian Chang, Frank E. Fish, Sunghwan Jung

Biology Faculty Publications

In nature, many animals dive into water at high speeds, e.g., humans dive from cliffs, birds plunge, and aquatic animals porpoise and breach. Diving provides opportunities for animals to find prey and escape from predators and is a source of great excitement for humans. However, diving from high platforms can cause severe injuries to a diver. In this study, we demonstrate how similarity in the morphology of diving fronts unifies the slamming force across diving animals and humans. By measuring a time-averaged impulse that increases linearly with the impact height, we are able to estimate the unsteady hydrodynamic forces that …


Patient Compliance With Wearing Lower Limb Assistive Devices: A Scoping Review, Ayisha Bashir, Danae Dinkel, Iraklis Pipinos, Jason Johanning, Sara Myers 2022 University of Nebraska at Omaha

Patient Compliance With Wearing Lower Limb Assistive Devices: A Scoping Review, Ayisha Bashir, Danae Dinkel, Iraklis Pipinos, Jason Johanning, Sara Myers

Journal Articles

Objective

The aim of this scoping review was to identify information on compliance with wearing orthoses and other supportive devices, to discuss the barriers to adherence, and to suggest strategies for improvement based on these findings.

Methods

Online databases of PubMed, Web of Science, and the Cochrane Library were searched for articles about patients’ compliance with regard to lower limb assistive devices. In addition, a methodological quality control process was conducted. Studies were included if in the English language and related to compliance and adherence to the lower limb assistive device. Exclusion was based on first reading the abstract …


Peripheral Artery Disease Affects The Function Of The Legs Of Claudicating Patients In A Diffuse Manner Irrespective Of The Segment Of The Arterial Tree Primarily Involved, Todd Leutzinger, Panagiotis Koutakis, Matthew A. Fuglestad, Hafizur Rahman, Holly DeSpiegelaere, Mahdi Hassan, Molly Schieber, Jason Johanning, Nick Stergiou, G. Matthew Longo, George P. Casale, Sara A. Myers, Iraklis Pipinos 2022 University of Nebraska at Omaha

Peripheral Artery Disease Affects The Function Of The Legs Of Claudicating Patients In A Diffuse Manner Irrespective Of The Segment Of The Arterial Tree Primarily Involved, Todd Leutzinger, Panagiotis Koutakis, Matthew A. Fuglestad, Hafizur Rahman, Holly Despiegelaere, Mahdi Hassan, Molly Schieber, Jason Johanning, Nick Stergiou, G. Matthew Longo, George P. Casale, Sara A. Myers, Iraklis Pipinos

Journal Articles

Different levels of arterial occlusive disease (aortoiliac, femoropopliteal, multi-level disease) can produce claudication symptoms in different leg muscle groups (buttocks, thighs, calves) in patients with peripheral artery disease (PAD). We tested the hypothesis that different locations of occlusive disease uniquely affect the muscles of PAD legs and produce distinctive patterns in the way claudicating patients walk. Ninety-seven PAD patients and 35 healthy controls were recruited. PAD patients were categorized to aortoiliac, femoropopliteal and multi-level disease groups using computerized tomographic angiography. Subjects performed walking trials both pain-free and during claudication pain and joint kinematics, kinetics, and spatiotemporal parameters were calculated to …


Hip Torque Is A Mechanistic Link Between Sprint Acceleration And Maximum Velocity Performance: A Theoretical Perspective, Kenneth P. Clark, Laurence J. Ryan 2022 West Chester University of Pennsylvania

Hip Torque Is A Mechanistic Link Between Sprint Acceleration And Maximum Velocity Performance: A Theoretical Perspective, Kenneth P. Clark, Laurence J. Ryan

Kinesiology Faculty Publications

Sprinting performance is critical for a variety of sports and competitive activities. Prior research has demonstrated correlations between the limits of initial acceleration and maximum velocity for athletes of different sprinting abilities. Our perspective is that hip torque is a mechanistic link between these performance limits. A theoretical framework is presented here that provides estimates of sprint acceleration capability based on thigh angular acceleration and hip torque during the swing phase while running at maximum velocity. Performance limits were calculated using basic anthropometric values (body mass and leg length) and maximum velocity kinematic values (contact time, thigh range of motion, …


Screening And Assessment Of Cancer-Related Fatigue: A Clinical Practice Guideline For Health Care Providers, Mary I. Fisher, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone 2022 University of Dayton

Screening And Assessment Of Cancer-Related Fatigue: A Clinical Practice Guideline For Health Care Providers, Mary I. Fisher, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone

Physical Therapy Faculty Publications

Cancer-related fatigue (CRF) is the most common side effect of cancer treatment. Regular surveillance is recommended, but few clinical practice guidelines transparently assess study bias, quality, and clinical utility in deriving recommendations of screening and assessment methods. The purpose of this clinical practice guideline (CPG) is to provide recommendations for the screening and assessment of CRF for health care professions treating individuals with cancer. Following best practices for development of a CPG using the Appraisal of Guidelines for Research and Evaluation (AGREE) Statement and Emergency Care Research Institute (ECRI) Guidelines Trust Scorecard, this CPG included a systematic search of the …


Trustworthiness And Quality In Research For Clinical Application, Mary I. Fisher 2022 University of Dayton

Trustworthiness And Quality In Research For Clinical Application, Mary I. Fisher

Physical Therapy Faculty Publications

No abstract provided.


An Exploratory Analysis Of Gait Biomechanics And Muscle Activation In Pregnant Females With High And Low Scores For Low Back Or Pelvic Girdle Pain During And After Pregnancy, Jennifer J. Bagwell, Nicholas Reynolds, Jo Armour Smith, Michelle Walaszek, Hannah Runez, Kristina Lam, Julie Peterson, Dimitrios Katsavelis 2022 Creighton University

An Exploratory Analysis Of Gait Biomechanics And Muscle Activation In Pregnant Females With High And Low Scores For Low Back Or Pelvic Girdle Pain During And After Pregnancy, Jennifer J. Bagwell, Nicholas Reynolds, Jo Armour Smith, Michelle Walaszek, Hannah Runez, Kristina Lam, Julie Peterson, Dimitrios Katsavelis

Physical Therapy Faculty Articles and Research

Background

The purpose of this study was to compare gait kinematics, kinetics, and muscle activation between pregnant females with high and low scores for low back and/or pelvic girdle pain during and after pregnancy.

Methods

Twenty participants tested during second trimester, third trimester, and again post-partum. At each session, motion capture, force plates, and surface electromyography data were captured during self-selected velocity over-ground walking. Participants completed the Quebec Back Pain Disability Scale (QBPDS) and were assigned to high (QBPDS ≥15) or low pain groups (QBPDS

Findings

Nine participants met the high pain group criteria and 11 were low pain. During …


Effects Of A 4-Week Heart Rate Variability Biofeedback Intervention On Psychological And Performance Variables In Student-Athletes: A Pilot Study, Samantha R. Weber, Zachary K. Winkelmann, Eva V. Monsma, Shawn M. Arent, Toni Torres-McGehee 2022 Limestone University

Effects Of A 4-Week Heart Rate Variability Biofeedback Intervention On Psychological And Performance Variables In Student-Athletes: A Pilot Study, Samantha R. Weber, Zachary K. Winkelmann, Eva V. Monsma, Shawn M. Arent, Toni Torres-Mcgehee

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

PURPOSE: To examine the effects of a 4-week biofeedback intervention on coherence, psychological, and performance variables in collegiate student-athletes. METHODS: Thirteen student-athletes were randomly assigned to the intervention (one weekly biofeedback session for 4-weeks) or control group (no sessions). Data were collected at pre and post-intervention using weekly averaged coherence scores, psychological measures for depression, arousal, stress, resiliency, and performance outcome measures. RESULTS: A 3 (Time) x 4 (Week average) repeated measures ANOVA was independently conducted to examine differences between time and weekly coherence average for coherence scores. No significant differences were found for “at rest”, pre, or post-practice coherence …


The Effects Of Vitamin D Supplementation On Athletic Performance And Injury Prevention, Amani Adeeb Abushamma 2022 Wright State University

The Effects Of Vitamin D Supplementation On Athletic Performance And Injury Prevention, Amani Adeeb Abushamma

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Vitamin D supplementation has numerous effects on athletic performance and plays a significant role in preventing an athlete’s risk of getting injuries. Vitamin D has an impact on numerous physiological functions such as: bone health, muscle function, inflammatory response, and immune function. An athlete’s bone and muscle health are essential for maximum performance and career success. A bone fracture due to vitamin D deficiency can delay an athlete’s training and ultimately inhibit obtaining a collegiate scholarship and/or contract. A cross sectional study found that more than half of athletic trainers did not view 25-hydroxyvitamin D(25[OH]) testing and vitamin D supplementation …


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