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Research Proposal: Clarifying Any Interactions Between Cytoskeletal Proteins And The Aminopeptidase Pam-1, Alexis Ayala 2021 Ursinus College

Research Proposal: Clarifying Any Interactions Between Cytoskeletal Proteins And The Aminopeptidase Pam-1, Alexis Ayala

Biology Presentations

Caenorhabditis elegans is a transparent roundworm that functions as an ideal model organism for studying the complex processes that occur during embryonic cell division. The cell division process is comprised of distinct phases that ensure the development of a healthy and robust embryo. The cytokinesis phase is characterized by the formation of a contractile ring near the middle of the embryo. When this contractile ring constricts, the embryo can effectively divide into two cells. Recent work in the Lyczak laboratory has focused on better understanding how the aminopeptidase PAM-1 works in conjunction with cytoskeletal proteins to regulate the actomyosin cytoskeleton ...


Investigating The Effect Of The Wee-1.3 And Pam-1 Mutations On Meiosis After The Fertilization Of Oocytes In C. Elegans, Sophie Lear, Alex Bender 2021 Ursinus College

Investigating The Effect Of The Wee-1.3 And Pam-1 Mutations On Meiosis After The Fertilization Of Oocytes In C. Elegans, Sophie Lear, Alex Bender

Biology Presentations

Currently, we are working with two genes: pam-1, which functions in the asymmetric division in meiosis and corresponding polarity, and wee-1.3, which functions in oocyte maturation. The mutation pam-1 is known to disturb embryo viability and reduces the hatch rate to 2% in the worms. However, a rescue mutation, wee-1.3, is known to bring the hatch rate up to 42% because polarity and asymmetry defects are suppressed. From previous research we know that during meiosis, the pam-1 mutation results in meiotic exit delays and other mutant phenotypes such as failure of meiosis II. Currently, we are imaging and ...


The Effect Of Changing Substrate On Arctic Aquatic Invertebrates Abundance, Tom Dolman 2021 University of Maine at Farmington

The Effect Of Changing Substrate On Arctic Aquatic Invertebrates Abundance, Tom Dolman

Michael D. Wilson Symposium

Climate change is directly affecting tundra ecosystems in northern regions, and warming temperatures have caused discontinuous permafrost and thawing sediments across the region. This project investigates how increasing erosion and the foraging patterns of migratory snow geese may degrade habitat for aquatic invertebrates in the upper Mast River, located in Wapusk National Park, Manitoba, Canada. In the past two decades, many of the important species of aquatic invertebrates have shown declines. Declining invertebrate populations are predicted to affect aquatic ecosystems and decrease the resources available to shorebirds and waterfowl, which breed and migrate through this area.


The Interconnectivity Of Parkinson's Disease And Type Two Diabetes Mellitus, Erica Olfson 2021 Belmont University

The Interconnectivity Of Parkinson's Disease And Type Two Diabetes Mellitus, Erica Olfson

Honors Theses

This thesis is about the biochemical connection between Parkinson's disease and Type II Diabetes Mellitus.


The Perceived Differences In Employee Engagement Through Multiple Generations In The Workplace: An Hr Perspective, Ashley Dawson, Tammy Brown 2021 Liberty University

The Perceived Differences In Employee Engagement Through Multiple Generations In The Workplace: An Hr Perspective, Ashley Dawson, Tammy Brown

Liberty University Research Week

Undergraduate

Theoretical Proposal


Total Synthesis And Biological Evaluation Of Siderophores: Key To Develop Iron Chelators And Tackle Antibiotic Delivery To Gram-Negative Bacteria, .Pratibha Desman 2021 Oral Roberts University

Total Synthesis And Biological Evaluation Of Siderophores: Key To Develop Iron Chelators And Tackle Antibiotic Delivery To Gram-Negative Bacteria, .Pratibha Desman

Research Symposium

Siderophores are molecules that act as iron carriers in bacteria. As they sequester iron from the environment and penetrate bacterial cells through active transporters, they can bypass the porin-mediated transportation in Gram-negative bacteria. Therefore, conjugating antibiotics that lacks the ability to pass through porins to siderophores and forming “sideromycins” has been proven as a way to battle antibiotic resistance in Gram-negative bacteria. My research will focus on synthesizing two siderophores, catenulobactin B and talarazine A as well as their analogs and exploring their potential to synthesize sideromycins. These molecules will be synthesized in a modular way and their cytotoxicity, ability ...


Attenuation Of Angiomotin Expression Via Crispr In Triple-Negative Mammary Epithelia, Riley Andrews, William Ranahan, Ph.D. 2021 Oral Roberts University

Attenuation Of Angiomotin Expression Via Crispr In Triple-Negative Mammary Epithelia, Riley Andrews, William Ranahan, Ph.D.

Research Symposium

Breast cancer is the most commonly diagnosed form of cancer among women living in the United States, and it is characterized by uncontrolled cell growth in either the lobules or ducts of the breast tissue. Additionally, breast cancer accounts for the second highest number of cancer deaths, only trailing behind lung cancer. Current efforts to treat this form of cancer include various combinations of chemotherapy, mastectomy, radiation, and endocrine therapy; however, there is still a need for treatments with increased selectivity. Use of the CRISPR/Cas9 gene-editing tool is a method that could be used to directly target cancer cells ...


Clinical Overview Of Postural Orthostatic Tachycardia Syndrome (Pots), Sarah Davis, Celestino Velasquez 2021 Oral Roberts University

Clinical Overview Of Postural Orthostatic Tachycardia Syndrome (Pots), Sarah Davis, Celestino Velasquez

Research Symposium

Postural Orthostatic Tachycardia Syndrome, POTS, is a syndrome of the cardiovascular autonomic system with characteristic symptoms of tachycardia and orthostatic intolerance upon standing. The most commonly seen symptoms in-clinic include weakness, dizziness, rapid heartbeat, and palpitations upon standing. Other symptoms often reported but not prevalent for every patient are reduced exercise capacity, deconditioning, gastrointestinal disorders, dyspnea, gastrointestinal disorders, and brain fog. POTS affects mainly women (80%) of child-bearing years from ages 10-45. POTS has a 0.2 – 1.0% prevalence in developing countries. POTS is a syndrome and not a disease. It has an onset of symptoms that start after ...


2014 Health Demographics Of A Rural Nicaraguan Community, Andrew Guymon, Brianna McGowen, Emma Foster 2021 Oral Roberts University

2014 Health Demographics Of A Rural Nicaraguan Community, Andrew Guymon, Brianna Mcgowen, Emma Foster

Research Symposium

In December 2014, a team of church members and associated healthcare workers from Owasso First Assembly in Owasso, Oklahoma, provided a free, two-day clinic and health assessment to the rural community of La Ceiba Dudu in Nicaragua. Services included medical exams, basic medications, dental extractions, and over the counter reading glasses. This report is a retrospective review of the patient records documented at that clinic. We analyzed the prevalence of parasites across five age cohorts and searched for correlations between parasite diagnosis and various patient metrics, including BMI, age, and gender. We searched for a relationship between occupants per household ...


The Gut-Brain Axis And The Apparent Links To Autism Spectrum Disorders, MacGregor Thomas 2021 Oral Roberts University

The Gut-Brain Axis And The Apparent Links To Autism Spectrum Disorders, Macgregor Thomas

Research Symposium

In recent years, researchers have pushed the boundaries of understanding of the human microbiome. Studies have pointed towards the involvement of gut bacteria in human health for decades, but now scientists have begun to acquire a more comprehensive understanding of the symbiotic relationship that bacteria have with their hosts. Research shows that gut bacteria can influence an organism's neural and immune system development, behavior, mood, and even neurotransmitter concentrations. Like other systems in the human body, a delicate balance of homeostasis, acting through bidirectional communication between the central nervous system and the gut, keeps this system in check. Studies ...


Skin And Allergic Reactions To Stinging Ants, Bees, And Wasps (Insect: Hymenoptera), Hall Reed, Ph.D., Mary Christian Reed, M.D. 2021 Oral Roberts University

Skin And Allergic Reactions To Stinging Ants, Bees, And Wasps (Insect: Hymenoptera), Hall Reed, Ph.D., Mary Christian Reed, M.D.

Research Symposium

Most encounters with venomous arthropods involve stings from ants, wasps, and bees (Hymenoptera), most of which do not require professional medical treatment. However, Hymenoptera stings represent about a quarter (22%) of the annual 1 million emergency department visits due to noncanine bite and sting injuries in the United States in 2001-2010 (Langley et al., 2014). Many such sting reactions involve non-specific skin reactions involving intense localized pain, redness, itching and formation of a wheal at sting site. Although most sting reactions are not diagnostic of the stinging species, the pustule formation of the sting of the imported fire ant (Solenopsis ...


Oral Roberts University Scorecard Results And The Development Of Sustainable Campus Operations And Sustainability Education, Makayla Stapp 2021 Oral Roberts University

Oral Roberts University Scorecard Results And The Development Of Sustainable Campus Operations And Sustainability Education, Makayla Stapp

Research Symposium

Colleges have helped shape the future by developing their students into leaders who will address injustice worldwide. One injustice that has received a lot of attention lately is the lack of organizations' concern for the environment. Colleges have an opportunity to demonstrate the importance and rewards that are received while taking care of the environment. Through being transparent with other organizations and having students, faculty, staff involvement, colleges can promote sustainability efforts that will last for generations. For an organization to adequately care for all aspects of the environment, it must analyze how it responds to the triple bottom line- ...


Gene Annotation Of The Hypothetical Protein-Coding Genes Of Coxiella Burnetii, Jason Salvato, Celestino Velasquez 2021 Oral Roberts University

Gene Annotation Of The Hypothetical Protein-Coding Genes Of Coxiella Burnetii, Jason Salvato, Celestino Velasquez

Research Symposium

Genetic information of organisms and microorganisms has become readily accessible due to advances in genomic sequencing and bioinformatic technology. Despite these advances, there are numerous organisms with genome sequences that have yet to be annotated. Many of these genome sequences require manual annotation, which can uncover hypothetical protein-coding genes. Through the use of publicly available online bioinformatics tools, such as BLAST, T- COFFEE, TMHMM, SignalP, Phobius, and PSORTb, the functions of hypothetical protein- coding genes can be predicted from primary amino acid sequences. Two clusters of properties that aid in determining and predicting the hypothetical genes involve sequence similarity and ...


Gene Annotation Of The Hypothetical Protein-Coding Genes Of Yersinia Pestis, Bethany Wilkinson, Celestino Velasquez 2021 Oral Roberts University

Gene Annotation Of The Hypothetical Protein-Coding Genes Of Yersinia Pestis, Bethany Wilkinson, Celestino Velasquez

Research Symposium

Technological advances within the past two decades have allowed researchers the capacity to sequence and analyze any genome. However, while many organisms have had their genomes sequenced, hardly any have been manually interpreted to propose the organism’s hypothetical protein-coding genes’ functions. The primary amino acid sequences of the organism’s genes can be used to offer functions for the organism’s proteins. Online programs such as BLAST, T-COFFEE, MUSCLE, TMHMM, SignalP, Phobius, and PSORTb, identify several properties such as conserved domains, protein families, protein conformations, signal peptides, and transmembrane regions of the sequences. These elements can be examined to ...


Fagus Sylvatica (European Beech), #1009, Megan L. Trafford 2021 Salve Regina University

Fagus Sylvatica (European Beech), #1009, Megan L. Trafford

BIO 140 Arboretum Project

No abstract provided.


Tilia Cordata (Littleleaf Linden) #1059, Heather Noel McKee 2021 Salve Regina University

Tilia Cordata (Littleleaf Linden) #1059, Heather Noel Mckee

BIO 140 Arboretum Project

In this paper I studied the Tilia cordata, more commonly known as the Littleleaf Linden, over the course of three months. I included the history and uses of the Linden tree along with its symbolic value in European culture. This tree symbolizes friendship and peace which coincides with the critical concerns of the Sisters of Mercy.


Synthesis Of A Material For The Sensitive And Selective Sorption Of Perfluorooctanoic Acid, Alicia Loucks, Stephen Hobson 2021 Liberty University

Synthesis Of A Material For The Sensitive And Selective Sorption Of Perfluorooctanoic Acid, Alicia Loucks, Stephen Hobson

Liberty University Research Week

Undergraduate

Basic


The Characterization Of The Microbiome For The Northern Two-Lined Salamander (Eurycea Bislineata) And Its Ecological Interactions With The Pathogen Batrachochytrium Dendrobatidis, Kristen Enns, Matthew Becker 2021 Liberty University

The Characterization Of The Microbiome For The Northern Two-Lined Salamander (Eurycea Bislineata) And Its Ecological Interactions With The Pathogen Batrachochytrium Dendrobatidis, Kristen Enns, Matthew Becker

Liberty University Research Week

Undergraduate

Basic


Identification Of Hepatopancreatic Parasites Afflicting Crayfish And Associated Snails In Local Virginia Streams, Cara Arrasmith, Jonathan Tenerovich, Kyle J. Harris 2021 Liberty University

Identification Of Hepatopancreatic Parasites Afflicting Crayfish And Associated Snails In Local Virginia Streams, Cara Arrasmith, Jonathan Tenerovich, Kyle J. Harris

Liberty University Research Week

Undergraduate

Basic


The Cutaneous Microbiomes Of Appalachian Salamanders And Their Role As An Innate Defense Against The Pathogen Batrachochytrium Dendrobatidis​, Miranda Sheridan, Matthew Becker 2021 Liberty University

The Cutaneous Microbiomes Of Appalachian Salamanders And Their Role As An Innate Defense Against The Pathogen Batrachochytrium Dendrobatidis​, Miranda Sheridan, Matthew Becker

Liberty University Research Week

Undergraduate

Basic


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