Biophysics Commons

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Recent Articles in Biophysics

Genetic Parameters For Concentrations Of Minerals In Longissimus Muscle And Their Associations With Palatability Traits In Angus Cattle, R. G. Mateescu, A. J. Garmyn, Richard G. Tait Jr., Qing Duan, Q. Liu, Mary S. Mayes, Dorian J. Garrick, A. L. Van Eenennaam, D. L. VanOverbeke, G. G. Hilton, Donald C. Beitz, James M. Reecy Iowa State University

Genetic Parameters For Concentrations Of Minerals In Longissimus Muscle And Their Associations With Palatability Traits In Angus Cattle, R. G. Mateescu, A. J. Garmyn, Richard G. Tait Jr., Qing Duan, Q. Liu, Mary S. Mayes, Dorian J. Garrick, A. L. Van Eenennaam, D. L. Vanoverbeke, G. G. Hilton, Donald C. Beitz, James M. Reecy

Animal Science Publications and Papers

The objective of this study was to estimate genetic parameters for concentrations of minerals in LM and to evaluate their associations with beef palatability traits. Samples of LM from 2,285 Angus cattle were obtained and fabricated into steaks for analysis of mineral concentrations and for trained sensory panel assessments. Nine minerals, including calcium, copper, iron, magnesium, manganese, phosphorus, potassium, sodium, and zinc, were quantified. Restricted maximum likelihood procedures were used to obtain estimates of variance and covariance components under a multiple-trait animal model. Estimates of heritability for mineral concentrations in LM varied from 0.01 to 0.54. Iron ...


Genetic Parameters For Carnitine, Creatine, Creatinine, Carnosine, And Anserine Concentration In Longissimus Muscle And Their Association With Palatability Traits In Angus Cattle, R. G. Mateescu, A. J. Garmyn, M. A. O'Neil, Richard G. Tait Jr., Almass A. Abuzaid, Mary S. Mayes, Dorian J. Garrick, A. L. Van Eenennaam, D. L. VanOverbeke, G. G. Hilton, Donald C. Beitz, James M. Reecy Iowa State University

Genetic Parameters For Carnitine, Creatine, Creatinine, Carnosine, And Anserine Concentration In Longissimus Muscle And Their Association With Palatability Traits In Angus Cattle, R. G. Mateescu, A. J. Garmyn, M. A. O'Neil, Richard G. Tait Jr., Almass A. Abuzaid, Mary S. Mayes, Dorian J. Garrick, A. L. Van Eenennaam, D. L. Vanoverbeke, G. G. Hilton, Donald C. Beitz, James M. Reecy

Animal Science Publications and Papers

The objective of this study was to estimate genetic parameters for carnitine, creatine, creatinine, carnosine, and anserine concentration in LM and to evaluate their associations with Warner-Bratzler shear force (WBSF) and beef palatability traits. Longissimus muscle samples from 2,285 Angus cattle were obtained and fabricated into steaks for analysis of carnitine, creatine, creatinine, carnosine, anserine, and other nutrients, and for trained sensory panel and WBSF assessments. Restricted maximum likelihood procedures were used to obtain estimates of variance and covariance components under a multiple-trait animal model. Estimates of heritability for carnitine, creatine, creatinine, carnosine, and anserine concentrations in LM from ...


Investigation Of The Quaternary Structure Of An Abc Transporter In Living Cells Using Spectrally Resolved Resonance Energy Transfer, Deo R. Singh University of Wisconsin Milwaukee

Investigation Of The Quaternary Structure Of An Abc Transporter In Living Cells Using Spectrally Resolved Resonance Energy Transfer, Deo R. Singh

Theses and Dissertations

Förster resonance energy transfer (FRET) has become an important tool to study proteins inside living cells. It has been used to explore membrane protein folding and dynamics, determine stoichiometry and geometry of protein complexes, and measure the distance between two molecules. In this dissertation, we use a method based on FRET and optical micro-spectroscopy (OptiMiS) technology, developed in our lab, to probe the structure of dynamic (as opposed to static) protein complexes in living cells. We use this method to determine the association stoichiometry and quaternary structure of an ABC transporter in living cells. Specifically, the transporter we investigate originates ...


Resiliency To Bistability In The Neurons From The Pre-Bötzinger Complex, Treadwell D. Singfield II Georgia State University

Resiliency To Bistability In The Neurons From The Pre-Bötzinger Complex, Treadwell D. Singfield Ii

Georgia State Undergraduate Research Conference

No abstract provided.


The Effect Of The R1648h Sodium Channel Mutation On Neuronal Excitability: A Model Study, Christopher Locandro, Robert Clewley Georgia State University

The Effect Of The R1648h Sodium Channel Mutation On Neuronal Excitability: A Model Study, Christopher Locandro, Robert Clewley

Georgia State Undergraduate Research Conference

No abstract provided.


Switching Bistable Leech Heart Interneurons With A Pulse Of Current From Bursting To Silence, Aaron Gomez-Lugo Georgia State University

Switching Bistable Leech Heart Interneurons With A Pulse Of Current From Bursting To Silence, Aaron Gomez-Lugo

Georgia State Undergraduate Research Conference

No abstract provided.


Raman Spectroscopic Analysis Of Human Skin Tissue Sections Ex-Vivo: Evaluation Of The Effects Of Tissue Processing And Dewaxing, Syed Mehmood Ali, Franck Bonnier, Ali Tfayli, Helen Lambkin, Kathleen Flynn, Vincent McDonagh, Claragh Healy, Thomas Lee, Fiona Lyng, Hugh Byrne Dublin Institute of Technology

Raman Spectroscopic Analysis Of Human Skin Tissue Sections Ex-Vivo: Evaluation Of The Effects Of Tissue Processing And Dewaxing, Syed Mehmood Ali, Franck Bonnier, Ali Tfayli, Helen Lambkin, Kathleen Flynn, Vincent Mcdonagh, Claragh Healy, Thomas Lee, Fiona Lyng, Hugh Byrne

Articles

Raman spectroscopy coupled with K-means clustering analysis (KMCA) is employed to elucidate the biochemical structure of human skin tissue sections, and the effects of tissue processing. Both hand and thigh sections of human cadavers were analysed in their unprocessed and formalin fixed paraffin processed (FFPP) and subsequently dewaxed forms. In unprocessed sections, KMCA reveals clear differentiation of the stratum corneum, intermediate underlying epithelium and dermal layers for sections from both anatomical sites. The stratum corneum is seen to be relatively rich in lipidic content; the spectrum of the subjacent layers is strongly influenced by the presence of melanin, while that ...


Characterization Of Cardiomyopathy In A Mouse Model Of Duchenne Muscular Dystrophy (Dmd) Using Echocardiography, Dce-Ct, And Pet-Fdg, Seyed Hamed Moazami Western University

Characterization Of Cardiomyopathy In A Mouse Model Of Duchenne Muscular Dystrophy (Dmd) Using Echocardiography, Dce-Ct, And Pet-Fdg, Seyed Hamed Moazami

Electronic Thesis and Dissertation Repository

Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disease that is the result of a loss of functional dystrophin, which causes cardiomyocyte fibrosis and death, leading to cardiomyopathy. In this thesis, I have utilized dynamic contrast-enhanced computed tomography (DCE-CT), positron emission tomography-fluorodeoxyglucose (PET-FDG), echocardiography, and traditional histology to longitudinally assess disease progression and degree of cardiomyopathy in a murine model of DMD (mdx:utrn-/-). No significant changes were observed in the blood flow, blood volume, or cardiac volume measured via DCE-CT, nor in standard uptake value (SUV) of glucose as measured by PET-FDG in the left myocardium between and ...


Size And Shape Characterization Of Salt Dependent Thermoreversible Micelles Synthesized From Elastin-Like Polypeptides, Kaitlin W. Vandemark Cleveland State University

Size And Shape Characterization Of Salt Dependent Thermoreversible Micelles Synthesized From Elastin-Like Polypeptides, Kaitlin W. Vandemark

Undergraduate Research Posters 2012

Environmentally responsive nanoparticles synthesized from Elastin-Like Polypeptides (ELP) present a promising system for applications such as biosensors, drug delivery vehicles, and viscosity modifiers.


Characterizing Cbid And Bax Binding To Supported Lipid Bilayers With Single Molecule Resolution, Sanjeevan Shivakumar McMaster University

Characterizing Cbid And Bax Binding To Supported Lipid Bilayers With Single Molecule Resolution, Sanjeevan Shivakumar

Open Access Dissertations and Theses

Bid and Bax are proteins that play a key role in mitochondrial outer membrane permeabilization during apoptosis. Elucidating the molecular mechanisms regulating the function of these proteins is essential to understanding how apoptosis is altered in diseases and for developing therapies. In this thesis, a mitochondria-like supported lipid bilayer (SLB) system is established and used to characterize the membrane binding behaviour of cBid and Bax with single molecule resolution. The formation of SLBs on mica substrate was characterized and lipid diffusion in the plane of the membrane was measured by fluorescence correlation spectroscopy to be 2-6 µm2/s depending ...


Impacts Of Invasive Plants On Resource Selection And Thermoregulation By The Northern Copperhead (Agkistrodon Contortrix Mokasen), Evin T. Carter Indiana University – Purdue University Fort Wayne

Impacts Of Invasive Plants On Resource Selection And Thermoregulation By The Northern Copperhead (Agkistrodon Contortrix Mokasen), Evin T. Carter

Master's Theses

Conservation management for any wildlife species relies on an understanding of habitat use and spatial patterns with an increasing need to identify the anthropogenic factors affecting populations (Sanderson et al., 2002). In order to understand those anthropogenic factors, it is generally necessary to first gain an understanding of the basic resource use patterns exhibited by the population(s) of interest. The Northern Copperhead (Agkistrodon contortrix mokasen) is a medium sized North American pitviper (Family Crotalidae) occurring throughout most of the eastern United States. Populations are thought to be stable throughout the majority of its range, but it holds protected status ...