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The Contribution Of Local And Transport Processes To Phytoplankton Biomass Variability Over Different Timescales In The Upper James River, Virginia, Qubin Qin, Jian Shen 2018 Virginia Institute of Marine Science

The Contribution Of Local And Transport Processes To Phytoplankton Biomass Variability Over Different Timescales In The Upper James River, Virginia, Qubin Qin, Jian Shen

Articles

Although both local processes (photosynthesis, respiration, grazing, and settling), and transport processes (advective transport and diffusive transport) significantly affect local phytoplankton dynamics, it is difficult to separate their contributions and to investigate the relative importance of each process to the local variability of phytoplankton biomass over different timescales. A method of using the transport rate is introduced to quantify the contribution of transport processes. By combining the time-varying transport rate and high-frequency observed chlorophyll a data, we can explicitly examine the impact of local and transport processes on phytoplankton biomass over a range of timescales from hourly to annually. For ...


The Manuscript Works Of S. Fred Prince (1857-1951), Sarah Burke Cahalan, Jason W. Dean 2018 University of Dayton

The Manuscript Works Of S. Fred Prince (1857-1951), Sarah Burke Cahalan, Jason W. Dean

Marian Library/IMRI Faculty Publications

S. Fred Prince, a botanical illustrator and amateur scientist, is a largely unknown artist whose work on the American landscape demonstrates his eligibility to be considered in the lineage of self-taught illustrator-naturalists such as Mark Catesby and Genevieve Jones. In this article, we present a survey of extant Prince materials identified at time of writing, describing their contents and physical characteristics. Beyond this survey and description, we also provide a biographical sketch and timeline of Prince's life.


Altering Oligomerization Of Epha2 Via Mutations In The Intracellular Domain, Ryan W. Lingerak 2018 The University of Akron

Altering Oligomerization Of Epha2 Via Mutations In The Intracellular Domain, Ryan W. Lingerak

Honors Research Projects

Eph receptor tyrosine kinases (RTKs) are activated by membrane-bound ligands called ephrins. Eph RTKs are divided into two subclasses, each activated by a specific classes of the ligand ephrin. The overexpression of Eph receptors is correlated to cancer cell metastasis in several different types of cancers. Studies with the EphA2 extracellular domain (ECD) and ephrinA1 ligand have shown that upon binding of ephrin to the receptor, EphA2 undergoes increased oligomerization and activation. This indicates that oligomerization is intimately connected to kinase activity. High resolution crystal structures of the EphA2 ECD have revealed some details of these ligand bound oligomers, as ...


Potential For Climate Induced Methane Hydrate Dissociation, Graham MacWilliams 2018 Pomona College

Potential For Climate Induced Methane Hydrate Dissociation, Graham Macwilliams

Pomona Senior Theses

Methane hydrates are frozen deposits of methane and water found in high pressure or low temperature sediments. When these deposits destabilize, large quantities of methane can be emitted into the atmosphere. This is significant to climate change because methane has 25 times more greenhouse gas potential than Carbon Dioxide. Worldwide, it is estimated there are between 2500 and 10000 gigatons of methane stored in hydrate deposits. This represents more carbon than all fossil fuels on Earth. It is estimated that between 200 and 2000 gigatons of methane are stored in hydrates in Arctic waters acutely vulnerable to greenhouse warming. Over ...


Tea Induction Of Cyp6a8 Promoter In Drosophila Melanogaster, Fiona Retzer 2017 University of Tennessee, Knoxville

Tea Induction Of Cyp6a8 Promoter In Drosophila Melanogaster, Fiona Retzer

University of Tennessee Honors Thesis Projects

No abstract provided.


The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, Kimberly Kelsey 2017 Dominican University of California

The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, Kimberly Kelsey

Senior Theses and Capstone Projects

Type 1 Diabetics have various ways of managing their diabetes that have been studied for their effectiveness. Pregnancy in the Type 1 Diabetic has been understudied. It is known that Diabetics in general have poorer pregnancy outcomes because of poor glycemic control. This coupled with the fact that the body needs 3-4 times more insulin as pregnancy comes to an end makes managing blood glucose levels challenging for diabetics (Lowdermilk, 2016, p. 689). For the Type 1 Diabetic, there are two main ways to control diabetes: multiple daily injections using at least two type of insulin and continuous subcutaneous insulin ...


Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential For Endoplasmic Reticulum To Outer Mitochondrial Membrane Protein Transport., Kyle Salka, Shivaprasad Bhuvanendran, Kassandra Wilson, Petros Bozidis, Mansi Mehta, Kristin Rainey, Hiromi Sesaki, George H Patterson, Jyoti K. Jaiswal, Anamaris M. Colberg-Poley 2017 George Washington University

Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential For Endoplasmic Reticulum To Outer Mitochondrial Membrane Protein Transport., Kyle Salka, Shivaprasad Bhuvanendran, Kassandra Wilson, Petros Bozidis, Mansi Mehta, Kristin Rainey, Hiromi Sesaki, George H Patterson, Jyoti K. Jaiswal, Anamaris M. Colberg-Poley

Genomics and Precision Medicine Faculty Publications

Most nuclear-encoded mitochondrial proteins traffic from the cytosol to mitochondria. Some of these proteins localize at mitochondria-associated membranes (MAM), where mitochondria are closely apposed with the endoplasmic reticulum (ER). We have previously shown that the human cytomegalovirus signal-anchored protein known as viral mitochondria-localized inhibitor of apoptosis (vMIA) traffics from the ER to mitochondria and clusters at the outer mitochondrial membrane (OMM). Here, we have examined the host pathways by which vMIA traffics from the ER to mitochondria and clusters at the OMM. By disruption of phosphofurin acidic cluster sorting protein 2 (PACS-2), mitofusins (Mfn1/2), and dynamin related protein 1 ...


Plasma Fibroblast Growth Factor-21 Levels In Patients With Inborn Errors Of Metabolism, Brian Kirmse, Juan Cabrera-Luque, Omar Ayyub, Kristina Cusmano-Ozog, Kimberly A. Chapman, Marshall L. Summar 2017 George Washington University

Plasma Fibroblast Growth Factor-21 Levels In Patients With Inborn Errors Of Metabolism, Brian Kirmse, Juan Cabrera-Luque, Omar Ayyub, Kristina Cusmano-Ozog, Kimberly A. Chapman, Marshall L. Summar

Pediatrics Faculty Publications

Fibroblast growth factor-21 (FGF21) levels are elevated in patients with primary mitochondrial disorders but have not been studied in patients with inborn errors of metabolism (IEM) known to have secondary mitochondrial dysfunction. We measured plasma FGF21 by ELISA in patients with and without IEM. FGF21 levels were higher in patients with IEM compared to without IEM (370 pg/dL vs. 0–65 pg/dL). Further study of FGF21 as a biomarker in IEM is warranted.


Characterisation Of Cold Plasma Treated Beef And Dairy Lipids Using Spectroscopic And Chromatographic Methods, Chaitanya Sarangapani, David Dorran, Julie Dunne, Paula Bourke, Patrick Cullen 2017 Dublin Institute of Technology

Characterisation Of Cold Plasma Treated Beef And Dairy Lipids Using Spectroscopic And Chromatographic Methods, Chaitanya Sarangapani, David Dorran, Julie Dunne, Paula Bourke, Patrick Cullen

Articles

The efficacy of cold plasma for inactivation of food-borne pathogens in foods is established. However, insights on cold plasma-food interactions in terms of quality effects, particularly for oils and fats, are sparse. This study evaluated plasma-induced lipid oxidation of model matrices, namely dairy and meat fats. Product characterisation was performed using FTIR, 1H NMR and chromatographic techniques. The oxidation of lipids by cold plasma followed the Criegee mechanism and typical oxidation products identified included ozonides, aldehydes (hexanal, pentenal, nonanal and nonenal) and carboxylic acids (9-oxononanoic acid, octanoic acid, nonanoic acid), along with hydroperoxides (9- and 13-hydroperoxy-octadecadienoylglycerol species). However, these ...


Endothelial Cells, Bennie Liu 2017 Selected Works

Endothelial Cells, Bennie Liu

Bennie Liu

Endothelial cells form the inner lining of a blood vessel and provides an anticoagulant barrier between the vessel wall and blood. Endothelial cells also generate an antithrombotic surface that facilitates transit of plasma and cellular constituents throughout the vasculature. As a selective permeability barrier, the endothelial cell is a unique multifunctional cell with critical basal and inducible metabolic and synthetic functions. The endothelial cell reacts with physical and chemical stimuli within the circulation and regulates hemostasis, vasomotor tone, and immune and inflammatory responses. In addition, the endothelial cell is pivotal in angiogenesis and vasculogenesis.


Building Academic/Practitioner Teams For Human Rights Projects: Examples, Lessons Learned, And Pitfalls To Avoid, Theresa Harris 2017 American Association for the Advancement of Science

Building Academic/Practitioner Teams For Human Rights Projects: Examples, Lessons Learned, And Pitfalls To Avoid, Theresa Harris

The Social Practice of Human Rights: Charting the Frontiers of Research and Advocacy

Academics are increasingly interested in getting out of their classrooms and labs to contribute their knowledge, expertise, and resources to help communities develop evidence-based policies. In addition to post-election initiatives such as the March for Science and 314 Action, many academics are joining “without borders”-type programs and organizations that connect academics with opportunities to volunteer their time and talents for “social good.”

One of the longest-running of these is On-call Scientists, an initiative of the American Association for the Advancement of Science (AAAS) that connects human rights organizations with pro bono scientists across all fields — life, physical, behavioral, and ...


Characterization Of A Novel Mitochondrial Plasmid In Brassica, Mackenzie Strehle 2017 University of Nebraska - Lincoln

Characterization Of A Novel Mitochondrial Plasmid In Brassica, Mackenzie Strehle

UCARE Research Products

Possessing some of the largest and most complex genomes of any eukaryotic organelles, plant mitochondria are notorious for their rapidly rearranging genetic framework. In addition to containing a large and complex mitochondrial genome, the mitochondria of several plants in the genus Brassica have also been shown to contain an independent, self-replicating linear plasmid. Interestingly, the plasmid appears to be able to move independently between the cytoplasm and the mitochondria, and it can be paternally inherited, unlike the rest of the mitochondrial genome. The plasmid also has features similar to those of adenoviruses, including terminal inverted repeats and covalently bound proteins ...


Farm-Scale Testing Of Soybean Peroxidase And Calcium Peroxide For Surficial Swine Manure Treatment And Mitigation Of Odorous Vocs, Ammonia And Hydrogen Sulfide Emissions, Devin L. Maurer, Jacek A. Koziel, Kelsey Bruning, David B. Parker 2017 Iowa State University

Farm-Scale Testing Of Soybean Peroxidase And Calcium Peroxide For Surficial Swine Manure Treatment And Mitigation Of Odorous Vocs, Ammonia And Hydrogen Sulfide Emissions, Devin L. Maurer, Jacek A. Koziel, Kelsey Bruning, David B. Parker

Agricultural and Biosystems Engineering Publications

The swine industry, regulatory agencies, and the public are interested in farm-tested methods for controlling gaseous emissions from swine barns. In earlier lab- and pilot-scale studies, a renewable catalyst consisting of soybean peroxidase (SBP) mixed with calcium peroxide (CaO2) was found to be effective in mitigating gaseous emissions from swine manure. Thus, a farm-scale experiment was conducted at the university's 178-pig, shallow-pit, mechanically-ventilated swine barn to evaluate SBP/CaO2 as a surficial manure pit additive under field conditions. The SBP was applied once at the beginning of the 42-day experiment at an application rate of 2.28 ...


Pertinacity Volume 3 Issue 1, Yuri Hosokawa 2017 University of Connecticut - Storrs

Pertinacity Volume 3 Issue 1, Yuri Hosokawa

Pertinacity

No abstract provided.


Direct Antioxidant Properties Of Methotrexate: Inhibition Of Malondialdehyde-Acetaldehyde-Protein Adduct Formation And Superoxide Scavenging., Matthew C. Zimmerman, Dahn L. Clemens, Michael J. Duryee, Cleofes Sarmiento, Andrew Chiou, Carlos D. Hunter, Jun Tian, Lynell W. Klassen, James R. O'Dell, Geoffrey M. Thiele, Ted R. Mikuls, Daniel R. Anderson 2017 University of Nebraska Medical Center

Direct Antioxidant Properties Of Methotrexate: Inhibition Of Malondialdehyde-Acetaldehyde-Protein Adduct Formation And Superoxide Scavenging., Matthew C. Zimmerman, Dahn L. Clemens, Michael J. Duryee, Cleofes Sarmiento, Andrew Chiou, Carlos D. Hunter, Jun Tian, Lynell W. Klassen, James R. O'Dell, Geoffrey M. Thiele, Ted R. Mikuls, Daniel R. Anderson

Journal Articles: Cellular & Integrative Physiology

Methotrexate (MTX) is an immunosuppressant commonly used for the treatment of autoimmune diseases. Recent observations have shown that patients treated with MTX also exhibit a reduced risk for the development of cardiovascular disease (CVD). Although MTX reduces systemic inflammation and tissue damage, the mechanisms by which MTX exerts these beneficial effects are not entirely known. We have previously demonstrated that protein adducts formed by the interaction of malondialdehyde (MDA) and acetaldehyde (AA), known as MAA-protein adducts, are present in diseased tissues of individuals with rheumatoid arthritis (RA) or CVD. In previously reported studies, MAA-adducts were shown to be highly immunogenic ...


Regulation Of The Amyloid Precursor Protein By Prostaglandin J2, A Mediator Of Inflammation: Relevance To Alzheimer’S Disease, Teneka L. Jean-Louis 2017 The Graduate Center, City University of New York

Regulation Of The Amyloid Precursor Protein By Prostaglandin J2, A Mediator Of Inflammation: Relevance To Alzheimer’S Disease, Teneka L. Jean-Louis

All Graduate Works by Year: Dissertations, Theses, and Capstone Projects

Inflammation plays a major role in Alzheimer’s disease (AD). Investigating how specific mediators of inflammation contribute to neurodegeneration in AD is crucial. Our studies focused on cyclooxygenases, which are key enzymes in inflammation and highly relevant to AD. Cyclooxygenases (COX -1, constitutive; COX-2, inducible) have emerged as important determinants of AD pathogenesis and progression. COX-2 is highly induced in AD, correlating with AD severity, and COX-1 is also involved in AD. Cyclooxygenases are the rate-limiting enzymes that convert arachidonic acid into prostaglandins (PGs), the principal mediators of CNS neuroinflammation.

The overall GOAL of these studies was to address the ...


The Role Of Glutamate Neurotransmission In The Ventral Tegmental Area In The Expression Of Conditioned Approach Learning, Priscila Hachimine-Merli 2017 The Graduate Center, City University of New York

The Role Of Glutamate Neurotransmission In The Ventral Tegmental Area In The Expression Of Conditioned Approach Learning, Priscila Hachimine-Merli

All Graduate Works by Year: Dissertations, Theses, and Capstone Projects

Conditioned stimuli (CSs) come to function as CSs by acquiring the capacity to activate the same mesocorticolimbic dopamine (DA) neurons activated by primary rewards, producing conditioned activation of these neurons and their associated motivational states. This model stipulates that CSs activate mesocorticolimbic DA systems through the activation of glutamate receptors on DA neurons in the ventral tegmental area (VTA). We tested the hypothesis that glutamate receptor stimulation in the VTA is necessary for the expression of conditioned approach. Rats were tested in a conditioned approach protocol that consisted of 7 consecutive conditioning sessions (light presentations and food were paired), one ...


Do The Evolution: The Effect Of Ksr V. Teleflex On Biotechnology, Josh Harrison 2017 University of Oklahoma College of Law

Do The Evolution: The Effect Of Ksr V. Teleflex On Biotechnology, Josh Harrison

Oklahoma Journal of Law and Technology

No abstract provided.


Managing Nitrous Oxide Emissions In Agricultural Fields, Mark S. Coyne, Wei Ren 2017 University of Kentucky

Managing Nitrous Oxide Emissions In Agricultural Fields, Mark S. Coyne, Wei Ren

Mark S. Coyne

Agriculture is a major contributor to atmospheric nitrous oxide (N2O) (Smith et al., 2014; Tian et al., 2015). Unfortunately, nitrous oxide destroys stratospheric ozone (O3) which protects us from ultraviolet radiation (Cicerone, 1989) and it increases ground level O3, whichis an air pollutant threatening human health and food production. Nitrous oxide is also 298 times more potent than an equivalent amount of carbon dioxide (CO2) in terms of trapping and absorbing reflected solar radiation (Forster et al., 2007). Basic chemistry and physics assure us that increased levels of N2O in the atmosphere are ...


Stem-Boring Caterpillars Of Switchgrass In The Midwestern United States, Jarrad R. Prasifka, Jennifer E. Buhay, Thomas W. Sappington, Emily A. Heaton, Jeffrey Bradshaw, Michael E. Gray 2017 University of Illinois

Stem-Boring Caterpillars Of Switchgrass In The Midwestern United States, Jarrad R. Prasifka, Jennifer E. Buhay, Thomas W. Sappington, Emily A. Heaton, Jeffrey Bradshaw, Michael E. Gray

Emily Heaton

Lepidopteran stem borers were collected from switchgrass, Panicum virgatum L., tillers showing symptoms of infestation at seven locations in Illinois and Iowa, with additional observations made on larval and adult activity. Blastobasis repartella (Dietz) (Coleophoridae), whose only known host is switchgrass, was common in plots grown for >5 yr, whereas the polyphagous stalk borer, Papaipema nebris (Guenée) (Noctuidae), was abundant in newly established (i.e., first- and second year) switchgrass. Haimbachia albescens Capps (Crambidae) was collected from two locations in Illinois, making switchgrass the first known host for this species. Entry holes made by B. repartella and H. albescens were ...


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