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High-Dimensional Mediation Analysis Of Multi-Omics Data, Sunyi Chi 2024 The Texas Medical Center Library

High-Dimensional Mediation Analysis Of Multi-Omics Data, Sunyi Chi

Dissertations & Theses (Open Access)

Environmental exposures such as cigarette smoking influence health outcomes through intermediate molecular phenotypes, such as the methylome, transcriptome, and metabolome. Mediation analysis is a useful tool for investigating the role of potentially high-dimensional intermediate phenotypes in the relationship between environmental exposures and health outcomes. Rapid development of high-throughput technologies have made mediation analysis of multi-omics data critical to gain groundbreaking insights into the biological mechanisms underlying the disease etiology. This dissertation aims to develop mediation analysis methods that utilize the enormous amount of multi-omics data in assessing mechanisms of disease etiology. It contains three projects where I propose advanced mediation …


Exploring Application Of The Coordinate Exchange To Generate Optimal Designs Robust To Data Loss, Asher Hanson 2024 Utah State University

Exploring Application Of The Coordinate Exchange To Generate Optimal Designs Robust To Data Loss, Asher Hanson

All Graduate Theses and Dissertations, Fall 2023 to Present

The primary objective of this study is to evaluate the efficacy of the coordinate exchange (CEXCH) algorithm in the generation of robust optimal designs. The assessment involves a comparative analysis, wherein designs produced by the Point Exchange (PEXCH) Algorithm are employed as benchmarks for evaluating the efficiency of CEXCH designs. Three modified criteria, selected from the traditional alphabet criteria pool, are utilized to score each algorithm. To enhance the reliability of the comparative analysis, multiple rounds of validation are conducted, focusing on visual assessments, design scores, and criteria efficiencies. The findings from each round of validation contribute to a comprehensive …


Exploring Optimal Design Of Experiments For Random Effects Models, Ryan C. Bushman 2024 Utah State University

Exploring Optimal Design Of Experiments For Random Effects Models, Ryan C. Bushman

All Graduate Theses and Dissertations, Fall 2023 to Present

The majority of research in the field of optimal design of experiments has focused on producing designs for fixed effects models. The purpose of this thesis is to explore how the optimal design framework applies to nested random effects models. The object that is being optimized is the model information matrix. We explore the full derivation of the random effects information matrix to highlight the complexity of the problem and show how the optimization is a function of the model's parameters. In conjunction with this research, the ODVC (Optimal Design for Variance Components) package was built to provide tools that …


The Relationship Between Fatalities In Police Violence And Their Identifying Characteristics: Age, Gender, Race, And Region, Yuechu Hu 2024 University of Minnesota - Morris

The Relationship Between Fatalities In Police Violence And Their Identifying Characteristics: Age, Gender, Race, And Region, Yuechu Hu

Undergraduate Research Symposium 2024

Police violence, highlighted by the George Floyd incident in 2020, has intensified concerns about police brutality and perceived racism in U.S. law enforcement (AP News, 2022). Therefore, we intend to analyze Fatal Encounters data, which documents non-police deaths that occur in the presence of the police in the United States. By creating statistical tables and graphs, as well as applying time-series methods, classification and regression trees, and a multinomial logistic regression model, we find that males and transgender people are more likely than females to encounter victimization during police brutality enforcement for any cause of death. Victims older than 19 …


Artificial Intelligence Could Probably Write This Essay Better Than Me, Claire Martino 2024 Augustana College, Rock Island Illinois

Artificial Intelligence Could Probably Write This Essay Better Than Me, Claire Martino

Augustana Center for the Study of Ethics Essay Contest

No abstract provided.


A Systematic Review: Mirror Neurons & Schizophrenia, Yashesvi Sharma, Surajit Dey 2024 Roseman University of Health Sciences

A Systematic Review: Mirror Neurons & Schizophrenia, Yashesvi Sharma, Surajit Dey

Annual Research Symposium

This research project establishes a link between Mirror Neuron System (MNS) activity and this information's implications in treating and understanding schizophrenia, specifically, schizophrenic patients with negative symptoms.


Variable-Order Fractional Laplacian And Its Accurate And Efficient Computations With Meshfree Methods, Yixuan Wu, Yanzhi Zhang 2024 Missouri University of Science and Technology

Variable-Order Fractional Laplacian And Its Accurate And Efficient Computations With Meshfree Methods, Yixuan Wu, Yanzhi Zhang

Mathematics and Statistics Faculty Research & Creative Works

The variable-order fractional Laplacian plays an important role in the study of heterogeneous systems. In this paper, we propose the first numerical methods for the variable-order Laplacian (-Δ) α (x) / 2 with 0 < α (x) ≤ 2, which will also be referred as the variable-order fractional Laplacian if α(x) is strictly less than 2. We present a class of hypergeometric functions whose variable-order Laplacian can be analytically expressed. Building on these analytical results, we design the meshfree methods based on globally supported radial basis functions (RBFs), including Gaussian, generalized inverse multiquadric, and Bessel-type RBFs, to approximate the variable-order Laplacian (-Δ) α (x) / 2. Our meshfree methods integrate the advantages of both pseudo-differential and hypersingular integral forms of the variable-order fractional Laplacian, and thus avoid numerically approximating the hypersingular integral. Moreover, our methods are simple and flexible of domain geometry, and their computer implementation remains the same for any dimension d ≥ 1. Compared to finite difference methods, our methods can achieve a desired accuracy with much fewer points. This fact makes our method much attractive for problems involving variable-order fractional Laplacian where the number of points required is a critical cost. We then apply our method to study solution behaviors of variable-order fractional PDEs arising in different fields, including transition of waves between classical and fractional media, and coexistence of anomalous and normal diffusion in both diffusion equation and the Allen–Cahn equation. These results would provide insights for further understanding and applications of variable-order fractional derivatives.


Health And Healthcare: Designing For The Social Determinants Of Health And Blue Zones In North Nashville, Rebecca Tonguis, Honor Thomas, Olivia Hobbs 2024 Belmont University

Health And Healthcare: Designing For The Social Determinants Of Health And Blue Zones In North Nashville, Rebecca Tonguis, Honor Thomas, Olivia Hobbs

Belmont University Research Symposium (BURS)

Owned by North Nashville’s First Community Church, a now empty site in the Osage-North Fisk neighborhood of North Nashville has been identified as a potential site for a new location of The Store, in addition to a community-centric architectural development based on the social determinants of health and informed by the principles behind Blue Zones, the locations with the highest lifespans in the world. Opened by Brad Paisley and Kimberly Williams-Paisley, The Store is a free grocery store that “allow[s] people to shop for their basic needs in a way that protects dignity and fosters hope”, for which North Nashville …


Performance Outcomes In Introductory Statistics: R Vs. Spss Usage At A Community College, Venessa Singhroy Ph.D., Bianca Sosnovski 2024 Queensborough Community College

Performance Outcomes In Introductory Statistics: R Vs. Spss Usage At A Community College, Venessa Singhroy Ph.D., Bianca Sosnovski

Publications and Research

This dataset corresponds to a study investigating the performance outcomes of students enrolled in two sections of an introductory statistics course at a community college in New York. The study, titled "Examining Differences in Performance Outcomes between Statistics Classes using High-coding vs. Low-coding Statistical Software Packages," explores the impact of utilizing different statistical software packages (R and SPSS) on student performance and motivation. The dataset comprises assessments administered to participants, including the Mathematics Motivation Questionnaire, Reading Comprehension Assessment, Algebra Assessment, Statistics Assessment, and Coding Assessment. Participants were divided into two sections: one utilizing R and the other utilizing SPSS for …


Lstm-Based Recurrent Neural Network Predicts Influenza-Like-Illness In Variable Climate Zones, Alfred Amendolara, Christopher Gowans, Joshua Barton, David Sant, Andrew Payne 2024 Noorda College of Osteopathic Medicine

Lstm-Based Recurrent Neural Network Predicts Influenza-Like-Illness In Variable Climate Zones, Alfred Amendolara, Christopher Gowans, Joshua Barton, David Sant, Andrew Payne

Annual Research Symposium

Purpose: Influenza virus is responsible for a recurrent, yearly epidemic in most temperate regions of the world. For the 2021-2022 season the CDC reports 5000 deaths and 100,000 hospitalizations, a significant number despite the confounding presence of SARS-CoV-2. The mechanisms behind seasonal variance in flu burden are not well understood. Based on a previously validated model, this study seeks to expand understanding of the impact of variable climate regions on seasonal flu trends. To that end, three climate regions have been selected. Each region represents a different ecological region and provides different weather patterns showing how the climate variables impact …


Research On Chinese Data Sovereignty Policy Based On Lda Model And Policy Instruments, Han QIAO, Junru XU 2024 School of Economics and Management, University of Chinese Academy of Sciences, Beijing 100190, China MOE Social Science Laboratory of Digital Economic Forecasts and Policy Simulation, University of Chinese Academy of Sciences, Beijing 100190, China

Research On Chinese Data Sovereignty Policy Based On Lda Model And Policy Instruments, Han Qiao, Junru Xu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Data sovereignty has become an important component of national sovereignty in the dual context of the digital economy development and the overall national security concept. Major countries and regions are actively carrying out data sovereignty strategic deployment and engaging in fierce competition in data resources, data technology, and data rules. This work adopts the policy text analysis method to study China’s data sovereignty policy, and employs the LDA model and policy instruments to quantitatively analyze the process evolution and thematic characteristics of China’s data sovereignty policy. Drawing on these findings, this study comprehensively considers the global data sovereignty policy and …


Application And Effectiveness Of Artificial Intelligence For The Border Management Of Imported Frozen Fish In Taiwan, Wen-Chin Tu, Wan-Ling Tsai, Chi-Hao Lee, Chia-Fen Tsai, Jen-Ting Wei, King-Fu Lin, Shou-Mei Wu, Yih-Ming Weng 2024 Food and Drug Administration, Ministry of Health and Welfare, Taipei, Taiwan

Application And Effectiveness Of Artificial Intelligence For The Border Management Of Imported Frozen Fish In Taiwan, Wen-Chin Tu, Wan-Ling Tsai, Chi-Hao Lee, Chia-Fen Tsai, Jen-Ting Wei, King-Fu Lin, Shou-Mei Wu, Yih-Ming Weng

Journal of Food and Drug Analysis

In Taiwan, the number of applications for inspecting imported food has grown annually and noncompliant products must be accurately detected in these border sampling inspections. Previously, border management has used an automated border inspection system (import food inspection (IFI) system) to select batches via a random sampling method to manage the risk levels of various food products complying with regulatory inspection procedures. Several countries have implemented artificial intelligence (AI) technology to improve domestic governmental processes, social service, and public feedback. AI technologies are applied in border inspection by the Taiwan Food and Drug Administration (TFDA). Risk management of border inspections …


A Novel Fuzzy Time Series Forecasting Method Based On Probabilistic Fuzzy Set And Cpbd Approach, Krishna Kumar Gupta, Suneet Saxena 2024 Shri Ram Murti Smarak College of Engineering and Technology

A Novel Fuzzy Time Series Forecasting Method Based On Probabilistic Fuzzy Set And Cpbd Approach, Krishna Kumar Gupta, Suneet Saxena

Applications and Applied Mathematics: An International Journal (AAM)

Probabilistic fuzzy set is used to model the non-probabilistic and probabilistic uncertainties simultaneously in the system. This study proposes a cumulative probability-based discretization and probabilistic fuzzy set based novel fuzzy time series forecasting method. It also proposes a novel discretization approach based on cumulative probability to tackle the probabilistic uncertainty in partitioning of datasets. Gaussian probability distribution function has been used to construct probabilistic fuzzy set. The advantage of the proposed work is that it addresses the uncertainties due to randomness and fuzziness simultaneously and also improves accuracy rate in time series forecasting. A proposed forecasting method is applied on …


Stability Of Predator-Prey Model For Worm Attack In Wireless Sensor Networks, Rajeev Kishore, Padam Singh 2024 Galgotias College of Engineering and Technology

Stability Of Predator-Prey Model For Worm Attack In Wireless Sensor Networks, Rajeev Kishore, Padam Singh

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, we propose a predator-prey mathematical model for analyzing the dynamical behaviors of the system. This system is an epidemic model, and it is capable of ascertaining the worm's spreading at the initial stage and improving the security of wireless sensor networks. We investigate different fixed points and examine the stability of the projected model.


Thermal Performance Of Forced Convection Of Water- Nepcm Nanofluid Over A Semi-Cylinder Heat Source, Xiaoming Wang, Rassol H. Rasheed, Babak Keivani, Dheyaa J. Jasim, Abbas J. Sultan, Sajad Hamedi, Hamed Kazemi-Varnamkhasti, Soheil Salahshour, Davood Toghraie 2024 Missouri University of Science and Technology

Thermal Performance Of Forced Convection Of Water- Nepcm Nanofluid Over A Semi-Cylinder Heat Source, Xiaoming Wang, Rassol H. Rasheed, Babak Keivani, Dheyaa J. Jasim, Abbas J. Sultan, Sajad Hamedi, Hamed Kazemi-Varnamkhasti, Soheil Salahshour, Davood Toghraie

Mathematics and Statistics Faculty Research & Creative Works

1) Background: Phase change materials (PCMs) have been used statically, which has caused the use of these materials to face challenges. Encapsulating PCMs and combining them with the base fluid can significantly solve the problem of using PCMs in BTM systems. In the present study, based on computational fluid dynamics, forced convection heat transfer of nano-encapsulated phase change materials (NEPCM) in a BTM system are simulated. The main aim of the present research is to reduce the temperature at the surface of the hot cylinder. 2) Methods: In this research, we simulated lithium battery thermal management systems in both steady …


Identifying Rural Health Clinics Within The Transformed Medicaid Statistical Information System (T-Msis) Analytic Files, Katherine Ahrens MPH, PhD, Zachariah Croll, Yvonne Jonk PhD, John Gale MS, Heidi O'Connor MS 2024 University of Southern Maine, Muskie School, Maine Rural Health Research Center

Identifying Rural Health Clinics Within The Transformed Medicaid Statistical Information System (T-Msis) Analytic Files, Katherine Ahrens Mph, Phd, Zachariah Croll, Yvonne Jonk Phd, John Gale Ms, Heidi O'Connor Ms

Rural Health Clinics

Researchers at the Maine Rural Health Research Center describe a methodology for identifying Rural Health Clinic encounters within the Medicaid claims data using Transformed Medicaid Statistical Information System (T-MSIS) Analytic Files.

Background: There is limited information on the extent to which Rural Health Clinics (RHC) provide pediatric and pregnancy-related services to individuals enrolled in state Medicaid/CHIP programs. In part this is because methods to identify RHC encounters within Medicaid claims data are outdated.

Methods: We used a 100% sample of the 2018 Medicaid Demographic and Eligibility and Other Services Transformed Medicaid Statistical Information System (T-MSIS) Analytic Files for 20 states …


Effects Of Maternal Anthropometry On Infant Anthropometry: A Cross-Sectional Study At Public Hospital X In Ternate, Indonesia, Yuni Nurwati, Hardinsyah Hardinsyah, Sri Anna Marliyati, Budi Iman Santoso, Dewi Anggraini 2024 Department of Community Nutrition, Faculty of Human Ecology, Institut Pertanian Bogor University

Effects Of Maternal Anthropometry On Infant Anthropometry: A Cross-Sectional Study At Public Hospital X In Ternate, Indonesia, Yuni Nurwati, Hardinsyah Hardinsyah, Sri Anna Marliyati, Budi Iman Santoso, Dewi Anggraini

Kesmas

Infant anthropometry is an indicator of neonatal survival. This study aimed to determine the effects of maternal anthropometry on estimating infant anthropom­etry. This cross-sectional study on 173 pregnant women at Public Hospital X in Ternate, Indonesia, was conducted from August 2018 to March 2023. The el­igible criteria were pregnant women aged ≥18 years, single pregnancy, and antenatal care (ANC) visits to the same hospital. The variables used included ma­ternal anthropometric measurements (body weight, body height, third-trimester weight (TTW)), gestational weight gain (GWG), education, age, ANC visits, and gestational age at delivery (GAD). A logistic regression model was employed to estimate …


Implementation Of Digital Health In Addressing Global Threats: Lessons From The Use Of Technology During Covid-19 Pandemic In Indonesia, Naili Shifa, Anisa Tiasari, Kemal N. Siregar 2024 Department of Administration and Health Policy, Faculty of Public Health, Universitas Indonesia

Implementation Of Digital Health In Addressing Global Threats: Lessons From The Use Of Technology During Covid-19 Pandemic In Indonesia, Naili Shifa, Anisa Tiasari, Kemal N. Siregar

Kesmas

This research conducted a systematic literature review to explore the implementation of digital health in Indonesia, focusing on the digital health policies, usage during the COVID-19 pandemic, benefits, and lessons learned. The study identified 10 relevant journals through database searches and analyzed the trends in publication, productive journals, and top institutions involved in digital health research. The findings revealed an increasing interest in digital health, with a growing number of published articles from 2021 to 2023. ScienceDirect emerged as the most productive journal, followed by PubMed and MDPI. The University of Indonesia and the University of Gajah Mada were the …


Road Traffic Noise Annoyance And Cardiovascular Disease Risk In Population: A Case Series Study In Kota Bharu, Malaysia, Faridah Naim, Nurin H M Nasir 2024 Environmental and Occupational Health Program, School of Health Sciences, Universiti Sains Malaysia

Road Traffic Noise Annoyance And Cardiovascular Disease Risk In Population: A Case Series Study In Kota Bharu, Malaysia, Faridah Naim, Nurin H M Nasir

Kesmas

Noise pollution can cause annoyance, significantly threatening the population’s health and well-being. This study aimed to find an association between road traffic noise exposure and cardiovascular disease (CVD) risk among residents in Kota Bharu, Malaysia. This descriptive study used a case series approach and surveyed 34 residents in selected residential areas near main roads. An adapted questionnaire was distributed to residents using a purposive sampling method. Questions related to sociodemographic information, self-reporting about CVD, and road traffic noise assessment were asked to investigate the underlying risk factors for CVD. The average score of CVD assessment was classified as moderate risk. …


Optimizing Buying Strategies In Dominion, Nikolas A. Koutroulakis 2024 Georgia Southern University

Optimizing Buying Strategies In Dominion, Nikolas A. Koutroulakis

Rose-Hulman Undergraduate Mathematics Journal

Dominion is a deck-building card game that simulates competing lords growing their kingdoms. Here we wish to optimize a strategy called Big Money by modeling the game as a Markov chain and utilizing the associated transition matrices to simulate the game. We provide additional analysis of a variation on this strategy known as Big Money Terminal Draw. Our results show that player's should prioritize buying provinces over improving their deck. Furthermore, we derive heuristics to guide a player's decision making for a Big Money Terminal Draw Deck. In particular, we show that buying a second Smithy is always more optimal …


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