Social Work Commons^™

The Role Of Glucocorticoid Signaling In Prostate Cancer Health Disparities, Leanne W. Burnham

Loma Linda University Electronic Theses, Dissertations & Projects

African-American men are more likely to develop aggressive prostate cancer (PCa) and die from the disease than other ethnic groups. Glucocorticoid signaling is a contributing biological factor to worse PCa prognosis, and is emerging as a key driver of PCa progression in the absence of androgens. The mechanism involves glucocorticoids binding to glucocorticoid receptor (GR) and bypassing the androgen receptor (AR) signaling pathway to activate AR-target genes that promote tumor aggressiveness and therapy-resistance. This is problematic as African-American men have hypersensitive GR signaling and chronically-elevated levels of glucocorticoids linked to cumulative stressful life events. To explore the role of glucocorticoid …

The Relationship Between Tamoxifen And Depressive Symptoms In Women With Breast Cancer, Terry Marie Lynn

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine whether women with breast cancer and the presence of the drug tamoxifen, are more severely depressed than women with breast cancer and the absence of tamoxifen. Average Beck Depression Inventory (BDI) scores did not differ between the two sub-groups; however, two significant group differences were found. First, 10 women in the tamoxifen group had scores of zero (versus 4 in the absence of prescribed tamoxifen group). Research has shown that scores of zero do not always reflect an absence of depression. Second, the most severely depressed women (BDI scores in the 25 …

Posttraumatic Stress Disorder In Parents Of Traumatic Brain Injury Patients, Carol Farr

Loma Linda University Electronic Theses, Dissertations & Projects

Traumatic Brain Injury (TBI) produces cognitive, behavioral, and affective deficits with resulting problems such as improper social behavior, increased aggression, emotional, personality and characterological changes. The impact upon the survivor, the sibling, as well as the parental subsystem has been well documented in the literature. Post-Traumatic Stress Disorder (PTSD) has been diagnosed in several different types of trauma survivors, although rarely have individual psychological symptoms been studied in parents.

This research examined the possible vulnerability factors that are associated with TBI and their potential influence upon PTSD symptomology. Questionnaires were mailed to 266 parents of TBI patients with a response …

Examination Of The Predictive Validity Of Risk Assessment Screening, Patricia Mary Morressy

Loma Linda University Electronic Theses, Dissertations & Projects

Child Protective Services ( CPS) have been under growing pressure to implement risk assessment systems over the past ten years (Dueck, H. J., English, D.J., Depanfilis, and Moote, G.T. (1993). This emphasis has come largely from the increasing number of reported allegations of child abuse and neglect (Doueck, et. al.) However, increasingly individuals involved in custody battles use the CPS reporting system to retaliate against one another. Because these reported cases require the action of CPS, the increase in allegations has overburdened the system. As a result, resources have diminished and challenges to screeners to make accurate risk assessments have …

Identification Of Variables Influencing Women's Breast Cancer Detection, Sherri Duckworth Kemp

Loma Linda University Electronic Theses, Dissertations & Projects

This study investigated the variables influencing women's breast cancer detection behavior. Using social learning theory as an organizing framework. factors influencing women's decisions to seek breast cancer detection and the respondent's personal demographics were examined for their contribution to explaining women's decisions to seek breast cancer detection.

A [convience] sample from a university medical center provided data for the study. Data were gathered with a voluntary questionnaire. A total of 25 employees from the medical center participated in the study during the winter quarter of 1994.

The findings of the study provide insight into some of the variables affecting women's …