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Full-Text Articles in Psychology
Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki
Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki
Legacy Theses & Dissertations (2009 - 2024)
AbstractFear is an evolutionarily conserved mechanism that allows an organism to discern potential harm and act accordingly by engaging in defensive behaviors. While fear is an adaptive response, dysregulation of fear by means of a traumatic event can lead to psychiatric conditions such as post-traumatic stress disorder (PTSD). Animal research using rodents in Pavlovian context fear conditioning experiments allows for the ability to study the underlying neural circuitry of threat-appropriate and aberrant fear learning and memory that may contribute to PTSD. However, despite reports that women are more than two times more likely to develop PTSD compared to men, the …
Effect Of Neighborhood Socioeconomic Disadvantage On Brain Functional Connectivity And Structural Properties In Trauma-Exposed Adults, Elisabeth Kathleen Webb
Effect Of Neighborhood Socioeconomic Disadvantage On Brain Functional Connectivity And Structural Properties In Trauma-Exposed Adults, Elisabeth Kathleen Webb
Theses and Dissertations
Though there has been substantial progress towards understanding brain-behavior relationships and characterizing the neurobiology of psychiatric disorders, research has not translated as expected into novel prevention and treatment of mental health conditions. One limitation may be the emphasis on individual-level variables (e.g., income) and omission of relevant area-level factors (e.g., neighborhood socioeconomic disadvantage). Recently, attention has been directed towards identifying the biological mechanisms by which neighborhoods impact mental health. The chronic stress associated with living in a disadvantaged neighborhood promotes a cascade of maladaptive events, which in turn impact brain structure and functioning. The processes affected by chronic neighborhood stressors …
Neural Correlates Underlying The Interactions Between Anxiety And Cannabis Use In Predicting Motor Response Inhibition, Richard Ward
Neural Correlates Underlying The Interactions Between Anxiety And Cannabis Use In Predicting Motor Response Inhibition, Richard Ward
Theses and Dissertations
The ability to effectively withhold an inappropriate response is a critical feature of cognitive control. Prior research indicates alterations in neural processes required for motor response inhibition in anxious individuals, including those with posttraumatic stress disorder (PTSD), and those who engage in regular cannabis use. However, thus far most research has examined how anxiety-related symptoms and cannabis use influence response inhibition in isolation of one another. The current study examined the interactions between anxious symptomology and recent cannabis use in a sample that recently experienced a traumatic event using functional magnetic resonance imaging (fMRI) during the completion of a Stop-Signal …
Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder, Carissa Weis
Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder, Carissa Weis
Theses and Dissertations
Posttraumatic stress disorder (PTSD) is a heterogenous psychological disorder that may result from exposure to a traumatic event. Using functional magnetic resonance imaging (fMRI), symptoms of PTSD have been associated with aberrations in brain networks that emerge in the absence of a given cognitive demand or task, called resting state networks. Most previous research in resting state networks and PTSD has focused on aberrations in the static functional connectivity among specific regions of interest (ROI) in the brain and within canonical networks constrained by a priori hypotheses. However, dynamic fMRI, an approach that examines changes in brain network characteristics over …
Individual Differences, Economic Stability, And Fear Of Contagion As Risk Factors For Ptsd Symptoms In The Covid-19 Emergency, Adolfo Di Crosta, Rocco Palumbo, Daniela Marchetti, Irene Ceccato, Pasquale La Malva, Roberta Maiella, Mario Cipi, Paolo Roma, Nicola Mammarella, Maria Cristina Verrocchio, Alberto Di Domenico
Individual Differences, Economic Stability, And Fear Of Contagion As Risk Factors For Ptsd Symptoms In The Covid-19 Emergency, Adolfo Di Crosta, Rocco Palumbo, Daniela Marchetti, Irene Ceccato, Pasquale La Malva, Roberta Maiella, Mario Cipi, Paolo Roma, Nicola Mammarella, Maria Cristina Verrocchio, Alberto Di Domenico
Management, Marketing, and Organizational Communication Department Student Works
On January 30th 2020, the World Health Organization (WHO) declared the COVID-19 pandemic a Public Health Emergency of International Concern (PHEIC). Italy has been one of the most affected countries in the world. To contain further spread of the virus, the Italian government has imposed an unprecedented long-period lockdown for the entire country. This dramatic scenario may have caused a strong psychological distress, with potential negative long-term mental health consequences. The aim of the present study is to report the prevalence of high psychological distress due to the COVID-19 pandemic on the general population, especially considering that this aspect is …
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
Theses and Dissertations
Trauma exposure is prevalent and while most are resilient, some go on to develop post-traumatic stress disorder (PTSD)—an anxiety-related disorder that results from traumatic experience. The brain changes that result from traumatic experience and PTSD are not well understood. Further, little is known about what distinguishes those who are resilient after trauma from those at risk for developing PTSD. Previous work indicates white matter integrity may be a useful biomarker in predicting PTSD and researchers have found changes in the integrity of three white matter tracts—the cingulum bundle, corpus callosum (CC), and uncinate fasciculus (UF)—in the aftermath of trauma. However, …
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
Theses and Dissertations
Trauma exposure is prevalent and while most are resilient, some go on to develop post-traumatic stress disorder (PTSD)—an anxiety-related disorder that results from traumatic experience. The brain changes that result from traumatic experience and PTSD are not well understood. Further, little is known about what distinguishes those who are resilient after trauma from those at risk for developing PTSD. Previous work indicates white matter integrity may be a useful biomarker in predicting PTSD and researchers have found changes in the integrity of three white matter tracts—the cingulum bundle, corpus callosum (CC), and uncinate fasciculus (UF)—in the aftermath of trauma. However, …
Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones
Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones
Dissertations, Theses, and Capstone Projects
The study of how the brain acquires fearful memories has attracted considerable experimental attention, due in part to the promise of discovering novel therapeutic approaches for psychiatric disorders that are characterized by unusually strong and persistent traumatic memories. In recent years, extensive research has focused on studying the neural and molecular mechanisms by which fear memories are acquired, stored, and retrieved in the brain. Once acquired, fear memories may be attenuated using one of 2 procedures: 1) fear extinction, which involves repeated presentation of the fear-arousing stimulus in the absence of an aversive consequence, or 2) interference with the reconsolidation …
Social Work Trauma Interventions: Dialectical Behavioral Therapy, Kassie Baumann
Social Work Trauma Interventions: Dialectical Behavioral Therapy, Kassie Baumann
Senior Honors Theses
According to Lynne Weilart (2013), in her article on the reasons why people seek out therapy, trauma is the number one reason people attend counseling. Many different trauma-informed approaches are designed specifically to address the consequences of trauma and to facilitate healing. Some of these approaches are as follows: Cognitive Behavioral Therapy (CBT); Dialectical Behavioral Therapy (DBT);Mentalization Based Therapy (MBT); Trauma Systems Therapy (TST); Trauma Assessment Pathway (TAP); and Attachment, Self-Regulation, and Competency (ARC) (de Arellano, Danielson, Ko, & Sprauge, 2008). The effectiveness of each trauma intervention will be examined. DBT is one of these trauma interventions that is growing …
Dopamine D1 Receptor Activity In The Basolateral Amygdala Is Important For Mediating Fear, Reward And Safety Discrimination Learning, Ka Ho Ng
Open Access Theses
Post traumatic stress disorder (PTSD) patients frequently show impairment in safety learning (Jovanovic, Kazama, Bachevalier, & Davis, 2012). Since the amygdala is known to be critical for emotional processing(Wassum & Izquierdo, 2015) and dopamine signaling in the amygdala is important for mediating both fear and reward learning, current experiments examined the role of dopamine signaling in the BLA in mediating both safety learning and reward seeking. We manipulated dopamine D1 receptor activity with a D1 receptor agonist (SKF 38393) or D1 receptor antagonist (SCH23390) either systemically or infused directly into the BLA 20 minutes prior to training rats in a …
Ultrasonic Vocalizations As A Predictor Of Resilience To Intermittent Swim Stress-Induced Anxiety: An Investigation Of Re-Exposure Effects, Yandan Wang, Robert C. Drugan, Nathaniel Stafford
Ultrasonic Vocalizations As A Predictor Of Resilience To Intermittent Swim Stress-Induced Anxiety: An Investigation Of Re-Exposure Effects, Yandan Wang, Robert C. Drugan, Nathaniel Stafford
Honors Theses and Capstones
No abstract provided.
Effect Of Social Status On Behavioral And Neural Response To Stress, Daniel W. Curry, Kathleen E. Morrison, Matthew A. Cooper
Effect Of Social Status On Behavioral And Neural Response To Stress, Daniel W. Curry, Kathleen E. Morrison, Matthew A. Cooper
Senior Thesis Projects, 2009
Individuals respond differently to traumatic stress. Social status, which plays a key role in how animals experience and interact with their social environment, may influence how individuals respond to stressors. In this study, we used a conditioned defeat model to investigate whether social status alters susceptibility to the behavioral and neural consequences of traumatic stress. Conditioned defeat is a model in Syrian hamsters in which an acute social defeat encounter results in a long term increase in submissive behavior and a loss of normal territorial aggression. To establish social status, we weight matched and paired Syrian hamsters in daily aggressive …