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Full-Text Articles in Psychology

Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk Apr 2024

Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk

SC Upstate Research Symposium

Purpose Statement: Several studies have shown that aerobic exercise can have a positive impact on alleviating symptoms experienced by individuals with Parkinson's disease (PD). Despite this evidence, the potential benefits of exercise for both PD patients and their care partners (PD dyad) remain unexplored. This research project investigates the effectiveness, therapeutic collaborations, and physical outcomes of a virtual reality (VR) tandem cycling program specifically designed for PD dyads.

Methods: Following approval from the Prisma Health Institutional Review Board, individuals with PD were identified and screened by clinical neurologists. The pre-testing measures for PD dyads (N=9) included emotional and cognitive status …


Black Boys Om: A Case Study Of The Impacts Of Community And Culture On Wellness Practices, Khanh Pham Mar 2024

Black Boys Om: A Case Study Of The Impacts Of Community And Culture On Wellness Practices, Khanh Pham

Graduate Student and Postdoctoral Fellow Symposium

Black men continue to face health disparities due to systemic oppression. Research indicates that mind-body-spirit practices (MBSPs) can effectively improve mental and physical health, thereby reducing health disparities among Black men. However, MBSPs are often White-female-dominated practices, thus putting Black male practitioners at continued risks of under-representation and marginalization in MBSP spaces. The culturally specific nature of MBSP spaces may then be an important factor in MBSPs’ influence on Black men’s health. Therefore, we aimed to explore how culturally specific MBSP spaces impact Black male practitioners’ MBSPs. We collaborated with Black Boys OM (BBO), a global community of Black male …


Repetitive Negative Thinking As A Prospective Predictor Of Depression And Anxiety Symptoms In Autistic And Non-Autistic Incoming College Students, Erin Kckenney Mar 2024

Repetitive Negative Thinking As A Prospective Predictor Of Depression And Anxiety Symptoms In Autistic And Non-Autistic Incoming College Students, Erin Kckenney

Graduate Student and Postdoctoral Fellow Symposium

Background: Improving the understanding and treatment of mental health concerns, including depression and anxiety, are significant priorities for autistic adults (Benevides et al., 2020; Crane et al., 2019; Pellicano et al., 2014). While several theories have been proposed to explain the high prevalence of internalizing symptoms in autistic people, little longitudinal research has been done to investigate potential causal mechanisms. One potentially fruitful area of investigation is to explore how well-known contributors to depression/anxiety in the general population predict and/or moderate the development of internalizing symptoms in autistic individuals. Objectives: The current study investigates the relation of one established risk …


The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease, Noah Al-Hassan, Taha Al Hassan, Juan C. Lopez-Alvarenga, Maria Quinones, Seratna Guadarrama Mar 2024

The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease, Noah Al-Hassan, Taha Al Hassan, Juan C. Lopez-Alvarenga, Maria Quinones, Seratna Guadarrama

Research Symposium

Background: Periodontal disease (PD), affecting 20-50% of the global population is marked by biofilm-induced inflammation in oral tissues. Chronic PD results in systemic complications such as heart disease, stroke, and Alzheimer's. The red complex microbes, Porphyromonas gingivalis and Treponema denticola, play a pivotal role, penetrating the blood-brain barrier and contributing to neurodegeneration. Alzheimer's disease (AD), an irreversible neurodegenerative disorder, is linked to abnormal protein cleavage and potentially involves microbiologic components, including gram-positive cocci. Research suggests the presence of bacteria such as Porphyromonas, Actinomyces, and Treponema in autopsied AD brains. Investigating the microbiologic connection between PD and AD is crucial, considering …


Investigating Interrater-Reliability In Assessing Social Behavior Of Monodelphis Domestica, Bianca A. Camacho, Johanna Perez, Jatziry L. Escobedo, John L. Vandeberg, Mario Gil Mar 2024

Investigating Interrater-Reliability In Assessing Social Behavior Of Monodelphis Domestica, Bianca A. Camacho, Johanna Perez, Jatziry L. Escobedo, John L. Vandeberg, Mario Gil

Research Symposium

Background: Reliable, consistent, and objective data is a goal all studies aim to achieve, but many struggle to obtain when subjective biases between researchers can occur. Inter-rater reliability (IRR) is a statistical measure used to quantify the degree of agreement between researchers qualitatively scoring the same phenomenon. The primary goal of this study is to enhance the methodology used to achieve optimal IRR. Using an established ethogram, our team of researchers scored the social behavior of the adult gray short-tailed opossum (Monodelphis domestica) to propose an effective method for achieving high IRR that can contribute to future …


Gamma-Aminobutyric Acid (Gaba) Neurons And Perineuronal Nets (Pnn) In The Monodelphis Domestica And Relevance To Psychiatric Disorders, Jatziry Z. Luna Escobedo, Mariela Garcia, John L. Vandeberg, Mario Gil Mar 2024

Gamma-Aminobutyric Acid (Gaba) Neurons And Perineuronal Nets (Pnn) In The Monodelphis Domestica And Relevance To Psychiatric Disorders, Jatziry Z. Luna Escobedo, Mariela Garcia, John L. Vandeberg, Mario Gil

Research Symposium

Background/ Purpose: Gamma-aminobutyric acid (GABA) is an amino acid that serves as the central nervous system’s (CNS) main inhibitory neurotransmitter. By inhibiting nerve transmission, it works to lower neuronal excitability. Altered GABA levels have been associated with a variety of psychiatric disorders, for example Epilepsies, Parkinson’s Disease, and Schizophrenia. Perineuronal nets (PNN) are extracellular molecules that are released by neurons and glial cells that modulate many neuronal and glial functions by encapsulating the inhibitory cells and neurites. Altered PNN levels serve as a potential trigger to synaptic imbalance. The purpose of this study is to quantify and analyze the presence, …


Barriers To Mental Health Seeking Among Army Aviation Personnel: A Preliminary Report, Aric J. Raus Feb 2024

Barriers To Mental Health Seeking Among Army Aviation Personnel: A Preliminary Report, Aric J. Raus

National Training Aircraft Symposium (NTAS)

This research explores barriers to mental health seeking, self-reported symptoms, and perspectives on self-help mental-wellness options among U.S. Army Aviation Personnel. Safe aviation operations require constant focus and mental clarity. These requirements expand when considering the implications and added stress of military operations, especially in combat scenarios. Yet, recent studies demonstrate that aviation personnel avoid seeking healthcare due to fears of losing their medical certification. This report provides preliminary results from the first known study on barriers to mental health seeking among U.S. Army aviation personnel. Utilizing an anonymous survey instrument, facilitated primarily through Social Media recruiting of current and …


Evaluating The Oral Health-Related Quality Of Life Among Dental Patients In South India - A Descriptive Study, Dheekshitha P K, Sudeep C B Dr., Sunil P M Dr., Suji M Dr. Feb 2024

Evaluating The Oral Health-Related Quality Of Life Among Dental Patients In South India - A Descriptive Study, Dheekshitha P K, Sudeep C B Dr., Sunil P M Dr., Suji M Dr.

Annual Research Symposium

This study aims to evaluate the oral health-related quality of life among dental patients in South India.


A Preliminary Timeline Of The Midbrain Development In The Monodelphis Domestica Animal Model, Ismael Perez, John L. Vandeberg, Mario Gil Oct 2023

A Preliminary Timeline Of The Midbrain Development In The Monodelphis Domestica Animal Model, Ismael Perez, John L. Vandeberg, Mario Gil

Research Colloquium

Introduction: The Brazilian short-tailed opossum (Monodelphis Domestica) is an understudied animal model compared to the Mus musculus that has been identified as a perfect candidate to study neurodevelopment (Baggott, L. & Moore, H., 1990). What makes the Monodelphis Domestica a perfect specimen for neurodevelopment is that the embryo develops outside the pouch of the mother providing easy noninvasive access to track changes across different developmental stages (Mate et al., 1994).

Objective: The objective of the study is to compare the area and volume in the development of the Monodelphis’s midbrain across three different developmental stages. Our research is beneficial because …


Psychotropics Prescription In Primary Care, Ruthzaine Lopez Bolano Oct 2023

Psychotropics Prescription In Primary Care, Ruthzaine Lopez Bolano

Research Colloquium

Background: The study aimed to measure the prevalence of psychotropic prescriptions in primary care at four UTRGV clinical sites. Based on the results, this paper serves to inform and educate primary care providers of their current practices and treatment options when diagnosing mental health disorders and prescribing psychotropics.

Methods: This study used EMR data from January to March 2021 in four primary care clinics affiliated with the UT Health RGV system. Primary care patients from January to March 2021 and who were diagnosed with mood disorders (including Depression, Anxiety, and Bipolar Disorder) were included in this quality improvement study.

Results: …


Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil Oct 2023

Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil

Research Colloquium

Understanding the effects of stress on behavior and cognition is important due to its impact on mental health and wellbeing (Schneiderman et al. 2005). Translational animal research can contribute to the development of new treatments that can improve therapeutic outcomes and our understanding of the neurobiology of stress. In the present study, we complement behavioral stress reactivity with immunohistochemical localization of oxytocin in the hypothalamus, a neuropeptide that regulates stress (Neumann & Slattery, 2016). Oxytocin has potential therapeutic use for mental health disorders (Neumann & Slattery, 2016), and the effects of oxytocin seem to be sexually dimorphic (Love, 2018). Using …


Mind, Body And Race: A Look Into How Implicit Biases Influence The Perception Of Emotion, Faiza Ahmad, Adam Anderson, James Dalton Rounds, Christina Chick, Alize Hill Sep 2023

Mind, Body And Race: A Look Into How Implicit Biases Influence The Perception Of Emotion, Faiza Ahmad, Adam Anderson, James Dalton Rounds, Christina Chick, Alize Hill

Research Symposium

Background: Most research examining the effects of implicit race-based biases in emotion perception has focused on the perception of Black faces as being angry. Limited work has been done examining the perception of “approach” emotions such as fear. Furthermore, most studies have predominantly used White subjects. Our study examined the role of implicit racial biases in shaping the perception of both anger and fear in White, Black and Asian participants.

Methods: 78 participants completed a Go/NoGo task in which they were asked to categorize different race faces as portraying either anger or fear. Participants would be asked to press the …


From Bench To Bedside: Bridging The Gap Between Animal Behavior Research And The Study Of Human Personality And Psychopathology, William Reckley, Mario Gil Sep 2023

From Bench To Bedside: Bridging The Gap Between Animal Behavior Research And The Study Of Human Personality And Psychopathology, William Reckley, Mario Gil

Research Symposium

Background: Most psychopathology focuses on the current mental picture of an individual with some including relations to the past experience. One problem with the biomedical studies of psychopathologies is the difficulty in using animals to describe and model these mental states in humans. This difficult task has been confounded by the inability to classify animals in a way that will provide general models that will allow better translation to hypotheses in humans. Therefore, the present investigation explores statistical/research strategies to organize variables using lab animals to facilitate the translation of this information to humans.

Methods: Factor analysis/PCA was used to …


A Neurodevelopmental Perspective To Improve Innovation In Preventive Treatment Of Substance Use Disorders, Ismael Perez, John Vandeberg, Mario Gil Sep 2023

A Neurodevelopmental Perspective To Improve Innovation In Preventive Treatment Of Substance Use Disorders, Ismael Perez, John Vandeberg, Mario Gil

Research Symposium

Background: Midbrain dopaminergic neurons have been associated with substance use disorders (Blaess & Ang, 2015). Understanding their neurodevelopment during early stages of life is fundamental for innovating preventive care treatments. The animal model Monodelphis domestica has been proposed as an excellent candidate to study neurodevelopmental changes due to the ease of access to see changes in their embryonic development (Mate et al., 1994). The purpose of our study is to inform how brain cells, including and especially dopaminergic neurons, mature by quantifying their number during early development. Additionally, the study aims to compare different midbrain areas and track neurodevelopmental changes …


Residential Treatment Of Substance Use Disorder And Related Comorbidities In Older Adults, Dale J. Dyben Sep 2023

Residential Treatment Of Substance Use Disorder And Related Comorbidities In Older Adults, Dale J. Dyben

Research Symposium

Purpose: Substance Use Disorders (SUD) are a leading contributor to health problems and premature mortality in the United States. Stigma and misconceptions about persons with SUD contribute to negative outcomes. The misconception that older adults do not suffer from severe SUD has contributed to a paucity of treatment options that meet the unique needs this population.

Description: The Center for Older Adult Recovery (COAR) at Hanley Center in West Palm Beach, Florida provides a model for residential treatment of older 65 and older with severe SUD and related medical and mental health comorbidities. Older adults who meet DSM-V diagnostic …


The Impact Of Social Isolation On The Neural Pathways Of Dopamine Neurons In The Ventral Tegmental Area (Vta) And The Nucelus Accumbens (Nac): Implications For The Treatment Of Depression, Anxiety, And Drug Addiction., Cristian M. Botello, Sasawan Heingraj, John L. Vandeberg, Mario Gil Sep 2023

The Impact Of Social Isolation On The Neural Pathways Of Dopamine Neurons In The Ventral Tegmental Area (Vta) And The Nucelus Accumbens (Nac): Implications For The Treatment Of Depression, Anxiety, And Drug Addiction., Cristian M. Botello, Sasawan Heingraj, John L. Vandeberg, Mario Gil

Research Symposium

As the literature on the Monodelphis domestica continues to grow, it is important to contribute to the knowledge base regarding neural pathways and their role in social behavior in this species. Previous studies have provided evidence that increased activity in ventral tegmental area (VTA) dopamine neurons were associated with more social activity in mice. It is also known that in traditional rodent models, the Nucleus Accumbens (NAcc) is implicated in interaction reward processes like motivation; however, more research is needed to elucidate the role of the NAcc in social behavior of the M. domestica. The present study was designed …


Sports Wagering In The United States: What We Do And Don't Know, Joshua B. Grubbs, Shane W. Kraus May 2023

Sports Wagering In The United States: What We Do And Don't Know, Joshua B. Grubbs, Shane W. Kraus

International Conference on Gambling & Risk Taking

Abstract

In the wake of the Murphy vs. NCAA decision by the Supreme Court of the United States, over 30 states now permit sports betting and a majority of Americans now have access to this activity. Even so, much remains unknown about the effects of widespread access to sports betting in the U.S. The present work reports interim results of multi-year data collection efforts in the U.S. In April of 2022, a U.S. nationally representative sample of 2,806 Americans and an additional sample of 1,553 sports wagering people were recruited by YouGov opinion polling, with follow up data collected in …


Measurement Models Matter: How Retrospective Calendar Versus Global Reports Yield Different Estimates Of Treatment Outcome, Margaret L. Paul Bs, Maria E. Meinerding Ms, Jeremiah Weinstock Phd, Meredith K. Ginley, James P. Whelan Phd, Rory A. Pfund May 2023

Measurement Models Matter: How Retrospective Calendar Versus Global Reports Yield Different Estimates Of Treatment Outcome, Margaret L. Paul Bs, Maria E. Meinerding Ms, Jeremiah Weinstock Phd, Meredith K. Ginley, James P. Whelan Phd, Rory A. Pfund

International Conference on Gambling & Risk Taking

Abstract: Retrospective reports are less accurate than objective measures of behavior and must be interpreted with consideration of the amount of distortion and error introduced by this methodology. The Gambling-Timeline Followback (G-TLFB) method is the gold standard retrospective assessment tool that is designed to minimize such error by asking for a specific recall of precise gambling behavior day-by-day using recall aids as compared to a global summation over time (e.g., how many gambling days in last month, how much money gambled in the last month). It remains an empirical question whether this difference in measurement format, G-TLFB versus global reports, …


High Illusion Of Control Adolescents: A Moderated Mediation Analyses Of The Effects Of Forms Of Counterfactual Thinking And Gender In Problem Gambling And Gaming, Larry Okechukwu Awo Dr., George Nzeadi Duru Mr. May 2023

High Illusion Of Control Adolescents: A Moderated Mediation Analyses Of The Effects Of Forms Of Counterfactual Thinking And Gender In Problem Gambling And Gaming, Larry Okechukwu Awo Dr., George Nzeadi Duru Mr.

International Conference on Gambling & Risk Taking

Abstract

Three studies (Study 1, N = 322 male adolescents, Study 2, N = 401 male and female adolescents, and Study 3, longitudinal, N = 56 male and female adolescents) analyzed the effects cognitive and psychographic variables in the relationships among illusion of control (IC), problem gambling and problem gaming. Moderated mediation analyses results using PROCESS macro in the three studies confirmed: (1) the positive mediating effect of upward CFT in the association between IC and problem gambling and problem gaming; (2) the negative mediating effect of downward CFT in the association between IC and problem gambling and problem gaming; …


Psychosocial Characteristics Of Gambling Addicts – Does It Matter When They Start Their Treatment?, Neven Ricijas Phd, Dora Dodig Hundric Phd, Sabina Mandic Ma, Sanja Radic Bursac Ma, Davor Bodor Phd May 2023

Psychosocial Characteristics Of Gambling Addicts – Does It Matter When They Start Their Treatment?, Neven Ricijas Phd, Dora Dodig Hundric Phd, Sabina Mandic Ma, Sanja Radic Bursac Ma, Davor Bodor Phd

International Conference on Gambling & Risk Taking

Abstract:

Gambling disorder is well known as a hidden addiction and therefore is subjected to a prolonged time in seeking treatment. During the development of addiction, the psychosocial functioning is more openly or covertly disrupted, and gambling addicts manifest various problems and risky behaviors. At the same time, motivational mechanism for seeking professional help are complex and influenced by different individual circumstances.

This study was conducted with N=315 patients in the Daily Clinic for Gambling Addiction. The psychosocial functioning of the patients is assessed at the beginning of the treatment, while a specific aim of this paper is to explore …


Zoom Fatigue: Case Presentation And Brief Review, Alan Lucerna, James Espinosa, Risha Hertz, Robin Lahr, James Lee May 2023

Zoom Fatigue: Case Presentation And Brief Review, Alan Lucerna, James Espinosa, Risha Hertz, Robin Lahr, James Lee

Rowan-Virtua Research Day

In this review, we discuss the phenomenon of what has been called Zoom Fatigue—a sense of fatigue as well as physical and emotional stress that can be associated with teleconferencing (especially long teleconferences with minimal breaks). The Zoom Fatigue Scale is discussed as well as various theories to explain the phenomenon. Some preventive strategies are discussed.


End Of Life Symptom Management In The Emergency Department, Alice Chang, James Espinosa, Alan Lucerna May 2023

End Of Life Symptom Management In The Emergency Department, Alice Chang, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

The Emergency Department is at times the only place patients can turn to for symptom relief. In an aging population, this means that more patients are presenting to the ED towards the end of life (EOL). Emergency medicine (EM) prides itself as a specialty that handles disease-directed treatment for a variety of acute conditions. In contrast, palliative care (PC) is focused on improving the quality of life (QOL). It has become essential for EM physicians to care for patients who are not seeking life-sustaining measures, but instead quality of life interventions. Patients with serious illness, even hospice patients, present to …


Brief Review: Kano Model In Healthcare, James Espinosa, David Ho, Alan Lucerna, Henry Schuitema May 2023

Brief Review: Kano Model In Healthcare, James Espinosa, David Ho, Alan Lucerna, Henry Schuitema

Rowan-Virtua Research Day

Here we discuss the use of the Kano Model in the hypothetical example of a re-design of resident conference experience. Kano appreciated that there were a number of attributes to quality. These are discussed in this brief review.


Sex And Gender Differences In Attention-Deficit / Hyperactive Disorder (Adhd): A Literature Review, Kaitlyn N. Blair, Min Young Kim May 2023

Sex And Gender Differences In Attention-Deficit / Hyperactive Disorder (Adhd): A Literature Review, Kaitlyn N. Blair, Min Young Kim

Research Day

Background:

The American Medical Women's Association (AMWA) Sex and Gender Health Collaborative identified the need for a concise factsheet for clinicians outlining sex and gender differences in Attention Deficit Hyperactive Disorder (ADHD) as ADHD is underdiagnosed, undertreated, and frequently misdiagnosed in women due to lack of recognition of gender-specific presentation. AMWA's goal is to improve access and exposure to sex and gender differences in healthcare as few medical schools educate students on these differences. The poster summarizes the reviewed literature on the prevalence, diagnosis, referral for, prevention, clinical presentation, and treatment of ADHD with a goal to reduce sex and …


Revisiting The Global Measures Of Overall Neuropsychological Function And The Impact Of Race-Based Normative Data In Clinical And Forensic Populations, Zachary Dipasquale, Donald Masey, Robert A. Ditomasso, Gabriel Stanziano May 2023

Revisiting The Global Measures Of Overall Neuropsychological Function And The Impact Of Race-Based Normative Data In Clinical And Forensic Populations, Zachary Dipasquale, Donald Masey, Robert A. Ditomasso, Gabriel Stanziano

Research Day

This study aims to examine the impact of race-based normative data on global measures of overall neuropsychological functioning. Further, it examines the changes made to the Average Impairment Rating (AIR) in the context of race-based norming and the dismissal of a previously included measure, Picture Arrangement. The AIR is a commonly used index to classify the severity of diffuseness related to brain injury. Despite its use, the AIR has a very limited body of research describing the impact of racial norming on the index. Based on a review of the literature, the Picture Arrangement subtest removal was never researched in …


The Stigmatization Of Eating Disorders: The South Vs. The World, Maria Urbina Apr 2023

The Stigmatization Of Eating Disorders: The South Vs. The World, Maria Urbina

Scholars Day Conference

This is the PowerPoint of my Honors Thesis of the same title.


Impact Of Acute Stress, Sex, And Childhood Maltreatment On Fear Learning And Fear Generalization In A Fear-Potentiated Startle Paradigm, Kayla M. Boaz, Chloe N. Cordes, Cassidy L. Pfister, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Boyd R. Rorabaugh, Seth D. Norrholm, Phillip R. Zoladz Apr 2023

Impact Of Acute Stress, Sex, And Childhood Maltreatment On Fear Learning And Fear Generalization In A Fear-Potentiated Startle Paradigm, Kayla M. Boaz, Chloe N. Cordes, Cassidy L. Pfister, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Boyd R. Rorabaugh, Seth D. Norrholm, Phillip R. Zoladz

ONU Student Research Colloquium

Many researchers approach the etiology of trauma-, stressor-, and anxiety-related mental disorders from the perspective of classical conditioning processes gone awry. According to this view, abnormal associative relationships between conditioned and unconditioned stimuli may underlie pathological anxiety and result in unusually intense fear memories or fear memories that cannot be properly extinguished. Recent work has expanded on this view by showing that many psychological disorders involving pathological anxiety are associated with an exaggerated form of stimulus generalization, leading individuals with such disorders to respond with fear and anxiety to a variety of contexts and cues that should not be threatening. …


Low-Dose Psilocybin Enhances Novel Object Recognition But Not Inhibitory Avoidance In Adult Rats, Claire E. Miller, Colin R. Del Valle, Margaret M. Naylor, Heather R. Sparkman, Connor M. Cruea, Rachel E. Rice, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz Apr 2023

Low-Dose Psilocybin Enhances Novel Object Recognition But Not Inhibitory Avoidance In Adult Rats, Claire E. Miller, Colin R. Del Valle, Margaret M. Naylor, Heather R. Sparkman, Connor M. Cruea, Rachel E. Rice, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Given the recently renewed interest in using psychedelics to aid in the treatment of psychological disorders, we aimed to examine the impact of psilocybin, a 5-HT2A agonist, on learning and memory in rodents. Previous work has demonstrated that psilocybin and other 5-HT2A agonists can enhance fear conditioning, fear extinction, and novel object recognition (NOR). Thus, we predicted that low doses of psilocybin would enhance inhibitory avoidance (IA) and NOR memory. In the first experiment, adult male and female Sprague-Dawley rats underwent step-through IA training (involving 0.45, 0.65, or 1 mA scrambled footshock) and were injected intraperitoneally (i.p.) with …


Psilocybin Prevents Symptoms Of Hyperarousal And Enhances Novel Object Recognition In Rats Exposed To The Single Prolonged Stress Paradigm, Colin R. Del Valle, Heather R. Sparkman, Margaret M. Naylor, Connor M. Cruea, Rachel E. Rice, Claire E. Miller, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz Apr 2023

Psilocybin Prevents Symptoms Of Hyperarousal And Enhances Novel Object Recognition In Rats Exposed To The Single Prolonged Stress Paradigm, Colin R. Del Valle, Heather R. Sparkman, Margaret M. Naylor, Connor M. Cruea, Rachel E. Rice, Claire E. Miller, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Pharmacotherapy for stress-related psychological disorders remains inadequate. Patients who are treated with conventional pharmacological agents frequently report negligeable symptom reduction, and, in most cases, less than 50% experience full remission. Clearly, there is a need for additional pharmaceutical research into both established and novel approaches to alleviate these conditions. Over the past several years, there has been a renewed interest in the use of psychedelics to aid in the treatment of psychological disorders. Several studies have reported promising results in patients with major depression, anxiety disorders, and post-traumatic stress disorder (PTSD) following treatment with psychedelic agents such as lysergic acid …


Tunnel Vision, False Memories, And Intrusive Memories Following Exposure To The Trier Social Stress Test, Chloe N. Cordes, Cassidy L. Pfister, Kayla M. Boaz, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Shannon B. Carnes, Boyd R. Rorabaugh, Phillip R. Zoladz Apr 2023

Tunnel Vision, False Memories, And Intrusive Memories Following Exposure To The Trier Social Stress Test, Chloe N. Cordes, Cassidy L. Pfister, Kayla M. Boaz, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Shannon B. Carnes, Boyd R. Rorabaugh, Phillip R. Zoladz

ONU Student Research Colloquium

Most research examining the impact of stress on learning and memory has exposed participants to a stressor and measured how it affects learning and memory for unrelated material (e.g., list of words). Such work has been helpful, but it has not been the most translational to the human condition. When considering phenomena such as intrusive memories in post-traumatic stress disorder (PTSD) or an eyewitness's memory for a crime, it is most useful to know what an individual remembers about the stress experience itself, not unrelated information. In prior work, investigators used a modified version of the Trier Social Stress Test …