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Full-Text Articles in Psychology
Dermatoglyphic Measures In Relation To Depressive Symptoms Among Non-Clinical Adolescents And Young Adults, Yosefa A. Modiano
Dermatoglyphic Measures In Relation To Depressive Symptoms Among Non-Clinical Adolescents And Young Adults, Yosefa A. Modiano
Dissertations, Theses, and Capstone Projects
Depressive disorders are highly prevalent and can be devastating. Increasingly, depressive symptomatology is understood from a dimensional perspective such that non- or sub-clinical presentations may share a similar etiology. Depression etiology is believed to include genetic and environmental factors that may contribute to underlying vulnerability (diathesis) by way of neurodevelopment. Birth cohort studies have provided empirical evidence of the relationship between prenatal insult and later experience of adverse outcomes, including increased risk for depressive disorders. Retrospective investigation of the possible influence of prenatal disturbance on later experience of depressive symptoms has methodological limitations. Dermatoglyphic measurements offer a more methodologically viable …
Impact Of Neurodevelopmental Genes On The Trajectory Of Adhd Severity: A Pilot Study, Agnieszka Mlodnicka
Impact Of Neurodevelopmental Genes On The Trajectory Of Adhd Severity: A Pilot Study, Agnieszka Mlodnicka
Dissertations, Theses, and Capstone Projects
Attention-deficit/Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental disorder characterized by symptoms of inattention and hyperactivity, and is associated with delays in neural development. To assess the association of genes involved in neurodevelopment with symptoms and trajectory of ADHD, saliva was collected and genotyped from 145 participants from a longitudinal study of preschoolers who were followed annually for 7 years. We examined four single nucleotide polymorphisms (SNPs) in genes associated with neurodevelopment: neuregulin-1 (NRG-1; SNP rs3924999), neurotropin-3 (NT-3; SNP rs6489630), brain-derived neurotrophic factor (BDNF; rs6265), and regulator of G protein signaling 4 (RGS4; rs951439). Hierarchical linear modeling revealed that neuregulin-1 and …