Psychology Commons^™

Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil

Research Colloquium

Understanding the effects of stress on behavior and cognition is important due to its impact on mental health and wellbeing (Schneiderman et al. 2005). Translational animal research can contribute to the development of new treatments that can improve therapeutic outcomes and our understanding of the neurobiology of stress. In the present study, we complement behavioral stress reactivity with immunohistochemical localization of oxytocin in the hypothalamus, a neuropeptide that regulates stress (Neumann & Slattery, 2016). Oxytocin has potential therapeutic use for mental health disorders (Neumann & Slattery, 2016), and the effects of oxytocin seem to be sexually dimorphic (Love, 2018). Using …

Effects Of Development On Hpa Function Following Pubertal Stress, Brittany D. Elliott

Graduate Theses, Dissertations, and Problem Reports

For women, two of the greatest risk factors for affective disorders are adversity experienced during puberty and later becoming pregnant. We have created a translationally relevant mouse model where we address these complex risk factors. Previously, we discovered that pregnant mice (dams) that experienced chronic variable stress (CVS) during puberty display a blunted hypothalamic-pituitary-adrenal (HPA) response when exposed to an acute stressor. Interestingly, this alteration only first becomes apparent during pregnancy, which is a sensitive period for these effects due to normative neuroendocrine changes. Further investigation of the mechanisms underlying this dysfunction revealed altered gene expression in the paraventricular nucleus …

Negative Social Media And Its Influence On Athlete's Performance, Bernd R. Huber

Cal Poly Humboldt theses and projects

This study aimed to investigate the potential impact of negative social media content on athletes' cortisol levels and subsequent performance. The study focused on the change in cortisol levels and differences in free throw performance, based on previous research findings. We hypothesized that negative social media postings would increase the stress experienced by student-athletes, resulting in elevated cortisol levels and decreased performance. Additionally, participants (n = 8) completed a questionnaire to examine the interaction between preexisting fear and the biological stress response. Contrary to expectations, there was no significant change in stress response, and negative postings did not have …

Memory And Attention While Scuba Diving At Shallow And Deep Depths: An Open Water Study, Leanne Boucher, Joshua Feingold, Kelly Concannon, Stephanie Talavera, Jaime Tartar, W. Matthew Collins

Journal for Sports Neuroscience

SCUBA diving requires a high level of cognitive functioning, however, many divers anecdotally report poor memory and attentional skills while underwater. Few studies have documented cognitive deficits resulting from an open-water dive. Here, 23 divers completed both shallow (8 m) and deep (28 m) dives over two days in the open-water. The order of the dives was counterbalanced across participants. While at depth, they completed the State-Trait Anxiety Inventory to assess anxiety levels, learned and were tested on a list of 36 words, and completed the trail making task (TMT) to assess executive functioning. They also gave saliva samples to …

A Randomized Controlled Trial Of Psychological Outcomes Of Mobile Guided Resonant Frequency Breathing In Young Adults With Elevated Stress During The Covid-19 Pandemic, Al Amira Safa Shehab

Dissertations, Theses, and Capstone Projects

Deep breathing practices have shown promise in reducing stress, anxiety, and depression in different populations, including young adults. Specifically, resonant frequency breathing can exert an impact on stress response systems through the vagus nerve and the hypothalamo-pituitary-adrenal (HPA) axis. This may induce reductions in stress and improvement in emotion regulation. Young adults, including college students, tend to be at a higher risk for psychological distress, as they face several psychosocial challenges. The COVID-19 pandemic has imposed new and unique stressors that resulted in higher levels of stress and emotional symptoms and it has been shown that this may have placed …

Understanding Individual Differences Within Large-Scale Brain Networks Across Cognitive Contexts, Katherine L. Bottenhorn

FIU Electronic Theses and Dissertations

Historically, human neuroimaging has studied brain regions “activated” during behavior and how they differ between groups of people. This approach has improved our understanding of healthy and disordered brain function, but has two key shortcomings. First, focusing on brain activation restricts how we understand the brain, ignoring vital, behind-the-scenes processing. In the past decade, the focus has shifted to communication between brain regions, or connectivity, revealing networks that exhibit subtle, consistent differences across behaviors and diagnoses. Without activation-focused research’s constraints, connectivity-focused neuroimaging research more comprehensively assesses brain function. Second, focusing on group differences ignores substantial within-group heterogeneity and often imposes …

Behavioral, Endocrine, And Neural Responses To Stress In Postpartum And Nulliparous Rats : Potential Mechanisms Of Postpartum Stress Resilience, Joanna Medina

Legacy Theses & Dissertations (2009 - 2024)

Major depressive disorder is one of the most pervasive psychiatric illnesses in the United States. Women are at greater risk for developing depression, particularly during their childbearing years. Approximately 17% of new mothers develop postpartum depression within 4 weeks after parturition. The risk for postpartum depression is even greater in women who do not breastfeed or stop breastfeeding early. Major depressive disorder and postpartum depression share the same symptomology and common etiological bases. Dysregulated stress responses, dopamine activity, and neuroinflammation are recognized mechanisms for depression. The transition to motherhood encompasses physiological and behavioral adaptations in the brain essential for ensuring …

Characterization Of A Novel, Stress-Responsive Sexually Dimorphic Corticotropin-Releasing Factor Receptor 1 (Crfr1) Nucleus In The Rostral Anteroventral Periventricular Nucleus Of The Mouse, Zachary Julius Rosinger

Legacy Theses & Dissertations (2009 - 2024)

Within the United States, women are at double the risk of men to develop a stress-related mood disorder (e.g., anxiety or depression) during their reproductive years (Kornstein et al., 2000; Kessler et al., 2005). Many factors contribute to the potential sex difference in such disorders, including gonadal hormones (hypothalamic-pituitary-gonadal axis; HPG) and how they interact with the stress response system, or hypothalamic-pituitary-adrenal (HPA) axis. Corticotropin-releasing factor (CRF) signals through binding the GS-coupled receptor, CRF receptor 1 (CRFR1), and activity between CRF/CRFR1 regulates the hormonal and behavioral stress response (Chen et al., 1993; Bale and Vale, 2004; Heinrichs et al., 1995; …

Evaluation Of Neurobiological Risk Factors For Alcohol Consumption; Convergent Evidence For Predispositional Effects Of Brain Volume, David Baranger

Arts & Sciences Electronic Theses and Dissertations

Alcohol is one of the most widely used psychoactive substances and accounts for 5% of global disease burden. The goal of the present work is to help advance efforts to both identify prognostic markers of risk, and to understand the mechanisms by which alcohol consumption impacts health. Early life stress is one of the strongest predictors of mental illness, including alcohol dependence, and has been hypothesized to impact risk via modulation of striatal reward functions and reward learning. Studies examined the effect of stress on reward learning and processing, and tested for moderation by genetic and environmental risk. Results were …

Hpa Axis Genetic Variation And Life Stress Influences On Functional Connectivity In Resting State Networks, Tara Ann Miskovich

Theses and Dissertations

Stressful or traumatic experiences are a key risk factor for developing psychopathology, primarily through the impact that chronic stress has on hypothalamic-pituitary-adrenal (HPA) axis functioning. The HPA axis regulates the stress response but can become dysregulated with chronic activation and impact brain functioning. In addition to environmental stressors, genetic variation in genes in the HPA axis appear to influence HPA axis functioning and is also related to disruption in brain functioning, particularly in the context of high life stress. The current study focused on examining potential mechanisms through which trauma and stress interacts with HPA axis genes to impact key …

The Psychophysiological Correlates Of Personality, Trauma, Posttraumatic Stress Disorder And Social Support, Meghan E. Pierce

UNLV Theses, Dissertations, Professional Papers, and Capstones

Theories considering the etiology of psychopathy suggest that trauma exposure, specifically childhood maltreatment and sexual abuse, is related to the development of callous-unemotional traits in children and adolescents, which are precursors to psychopathic traits in adulthood. Furthermore, posttraumatic stress disorder has an opposite relationship with many of the emotional and behavioral components of the two-factor model of psychopathy. Specifically, PTSD is positively associated to IA and traits associated with it and negatively associated with FD. Thus, this study sought to expand upon the current theories of a trauma-based etiology of psychopathy by investigating the relationship between trauma, PTSD, and psychopathic …

Working Memory Impairments In Chromosome 22q11.2 Deletion Syndrome: The Roles Of Anxiety And Stress Physiology, Ashley F. P. Sanders

University of New Orleans Theses and Dissertations

Stress and anxiety negatively impact the working memory system by competing for executive resources. Broad memory deficits have been reported in individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS). We investigated anxiety and physiological stress reactivity in relation to visuospatial working memory impairments in 20 children with 22q11.2DS and 32 typically developing children (M = 11.10 years, SD = 2.95). Results indicate reduced post-stress RSA recovery and overall increased levels of cortisol in children with 22q11.2DS. Additionally, anxiety mediated the relationship between 22q11.2DS and visuospatial working memory impairment. However, there was no indication that stress response physiology mediated this association. …

Polymorphisms Of The Glucocorticoid Receptor Gene And The Association With Stress, Randall Beck, Michael J. Larson

Journal of Undergraduate Research

Polymorphisms in the GR gene are an interesting and important area of research as these polymorphisms may be associated with an attenuated ability to cope with stress. This project bridged an unexplored gap between cellular and environmental stress and the expression of the GR gene—specifically the Bcl1 polymorphism of the GR gene. Cellular stress is any damage caused to the cell that alters its ability to function properly (Milisav, 2011). The Bcl1 polymorphism has what are known as C and G alleles that are genotyped as either homozygous GG, homozygous CC, or heterozygous CG (Srivastava et al., 2011). The homozygous …

Polymorphisms Of The Glucocorticoid Receptor Gene And The Association With Stress, Randall Beck, Michael J. Larson

Journal of Undergraduate Research

Polymorphisms in the GR gene are an interesting and important area of research as these polymorphisms may be associated with an attenuated ability to cope with stress. This project bridged an unexplored gap between cellular and environmental stress and the expression of the GR gene—specifically the Bcl1 polymorphism of the GR gene. Cellular stress is any damage caused to the cell that alters its ability to function properly (Milisav, 2011). The Bcl1 polymorphism has what are known as C and G alleles that are genotyped as either homozygous GG, homozygous CC, or heterozygous CG (Srivastava et al., 2011). The homozygous …

Should Fish Feel Pain? A Plant Perspective, František Baluška

Animal Sentience

Key (2016) claims fish that fish do not feel pain because they lack the necessary neuronal architecture: their responses to noxious stimuli, according to Key, are executed automatically without any feelings. However, as pointed out by many of his commentators, this conclusion is not convincing. Plants might provide some clues. Plants are not usually thought to be very active behaviorally, but the evidence suggests otherwise. Moreover, in stressful situations, plants produce numerous chemicals that have painkilling and anesthetic properties. Finally, plants, when treated with anesthetics, cannot execute active behaviors such as touch-induced leaf movements or rapid trap closures after localizing …

The Temporal Nature Of The Acute Stress Response And Its Impact On Explicit Learning, Steven B. Hutchinson

Electronic Theses and Dissertations

Acute stress is commonly experienced by many throughout their lives. Given the demanding lifestyle of many career paths, it's important to gauge the influence of these stressors upon cognitive performance. The present dissertation focus' upon explicit learning in attempts to explore one avenue of the stress-cognition relationship. The Trier Social Stress Test (TSST) was used as a lab stressor for Experiments 1 and 2, in which participants are asked to give a speech and complete a difficult math task in front of 2 evaluators trained to monitor non-verbal behavior. Experiment 1 investigates the dynamic stress response during the minutes following …

The Influence Of Prenatal Stress On Behaviors Associated With Schizophrenia And Autism Spectrum Disorder., Harold Bauerle

Graduate College Dissertations and Theses

Disorders such as schizophrenia (SCZ) and austism spectrum disorder (ASD) have long been associated with prenatal stress. In these three experiments, we attempted to correlate stress during gestation with behaviors considered to have good facial validity with SCZ and ASD in both juvenile and adult animals. To differentiate the effects of prenatal stress (PS) from the effects of early life stress due to a dam's behavior (MS), half of offspring animals were cross fostered to dams treated in the alternative condition as the offspring during pregnancy in experiments 2 and 3. In experiment 1, but not in 2 or 3, …

Cortisol Levels And Voltage Conditions Of College Students, Adriana Steffens

Walden Dissertations and Doctoral Studies

There is a limited research base on low voltage brain conditions, which are characterized by electrical activity being measured at below 20 microvolts. The purpose of this study was to examine the relationship between saliva cortisol levels and voltage using an EGG in a college student population. Illuminating this relationship is important to inform how low voltage conditions can affect daily memory and cognitive functioning of undergraduate college students that may be a result of stress. The college student population may be vulnerable to the low voltage condition because of stress from the transition between teenage and adult life and …

Alcohol Use Disorders And An Fmri Stress Task: A Connectivity Analysis, Natasha E. Wright

Theses and Dissertations

Little research has been conducted on neuronal stress processing in individuals

with alcohol dependence (AD). The present study examined neural stress response in AD individuals compared to controls using an fMRI stress task, assessing amygdala

activation and its connectivity to the medial prefrontal cortex (mPFC). Further, the study

analyzed the impact of hormone levels and subjective stress on frontal-limbic

connectivity patterns.

Ten abstinent AD individuals and 11 controls were recruited. Subjects

participated in an fMRI stress task. A region of interest (amygdala) analysis was

conducted using area-under-the-curve. This activation was then examined in a whole brain functional connectivity analysis. Follow-up …

Associations Between Hypothalamic-Pituitary-Adrenal Axis System Gene Variants And Cortisol Reactivity In Preschoolers: Main Effects And Gene-Environment Interactions, Haroon I. Sheikh

Electronic Thesis and Dissertation Repository

Exposure to stressful events during early development has consistently been shown to produce long lasting effects on the hypothalamic-pituitary-adrenal (HPA) axis, which may increase vulnerability to mood and anxiety disorders. Recently reported genetic association studies indicate that these disorders may be influenced, in part, by gene-environment interactions (GxE) involving polymorphisms within the corticotrophin-releasing hormone and monoaminergic system genes. However, little is known about how genetic variants and life stress work to shape children’s neuroendocrine reactivity and emerging symptoms. Therefore, the aim of this thesis is to examine main effects of candidate genes and GxE on the neuroendocrine stress response and …

Is Pressure Stressful? The Impact Of Pressure On The Stress Response And Category Learning, Shannon L. Mccoy, Steven B. Hutchinson, Lauren Hawthorne, Brandon J. Cosley, Shawn W. Ell

Psychology Faculty Scholarship

We examine the basic question of whether pressure is stressful. We propose that when examining the role of stress or pressure in cognitive performance it is important to consider the type of pressure, the stress response, and the aspect of cognition assessed. In Experiment 1, outcome pressure was not experienced as stressful but did lead to impaired performance on a rule-based (RB) category learning task and not a more procedural information-integration (II) task. In Experiment 2, the addition of monitoring pressure resulted in a modest stress response to combined pressure and impairment on both tasks. Across experiments, higher stress appraisals …

Autonomic And Behavioral Reactivity To An Acute Laboratory Stressor, Jeremy C. Peres

University of New Orleans Theses and Dissertations

Stress has been widely shown to directly influence people’s emotional and behavioral processing as well as their underlying biological systems. This project examined physiological and behavioral responses as indicators of stress and coping in the context of a psychosocial stressor in a controlled laboratory setting. We examined the association between indicators of behavioral coping and underlying physiological reactivity within participants while experiencing stress. Participants included 68 emerging adults. Physiological measures include autonomic biomarkers (e.g., heart-rate, skin conductance) at rest and during the stressor while behavioral indicators that were coded include acute verbal and non-verbal actions exhibited by participants during the …

Adaptive Significance Of Natural Variations In Maternal Care In Rats: A Translational Perspective, Annaliese K. Beery, Darlene D. Francis

Neuroscience: Faculty Publications

A wealth of data from the last fifty years documents the potency of early life experiences including maternal care on developing offspring. A majority of this research has focused on the developing stress axis and stress-sensitive behaviors in hopes of identifying factors impacting resilience and risk-sensitivity. The power of early life experience to shape later development is profound and has the potential to increase fitness of individuals for their environments. Current findings in a rat maternal care paradigm highlight the complex and dynamic relation between early experiences and a variety of outcomes. In this review we propose adaptive hypotheses for …

Effect Of Social Status On Behavioral And Neural Response To Stress, Daniel W. Curry, Kathleen E. Morrison, Matthew A. Cooper

Chancellor’s Honors Program Projects

No abstract provided.

Effect Of Social Status On Behavioral And Neural Response To Stress, Daniel W. Curry, Kathleen E. Morrison, Matthew A. Cooper

Senior Thesis Projects, 2009

Individuals respond differently to traumatic stress. Social status, which plays a key role in how animals experience and interact with their social environment, may influence how individuals respond to stressors. In this study, we used a conditioned defeat model to investigate whether social status alters susceptibility to the behavioral and neural consequences of traumatic stress. Conditioned defeat is a model in Syrian hamsters in which an acute social defeat encounter results in a long term increase in submissive behavior and a loss of normal territorial aggression. To establish social status, we weight matched and paired Syrian hamsters in daily aggressive …

Salivary Cortisol, Psychological Stress And Depressive Symptoms Among Patients Undergoing Colon Cancer Screenings, Allyson Reid

Honors Scholar Theses

As the second leading cause of cancer-related deaths in the United States, colon cancer has a high cure rate if detected early by a colonoscopy (U.S.

Cancer Statistics Working Group, 2007). However, more than 41 million at-risk Americans are not properly receiving colonoscopy screenings according to the recommendations of the Center for Disease Control. This study provides insight into the physiological and psychological benefits of the colonoscopy procedure over and above cancer detection and prevention. Thirty-six patients receiving colonoscopic screening at the University of Connecticut Health Center participated in this study. A questionnaire battery that assessed perceived stress, depressive symptoms, …

Ethological Causes And Consequences Of The Stress Response, Neil Greenberg, James A. Carr, Cliff H. Summers

Neil Greenberg

Stress involves real or perceived changes within an organism or in the environment that activate an organism’s attempts to cope by means of evolutionarily ancient neural and endocrine mechanisms. Responses to acute stressors involve catecholamines released in varying proportion at different sites in the sympathetic and central nervous systems. These responses may interact with and be complemented by intrinsic rhythms and responses to chronic or intermittent stressors involving the hypothalamic-pituitary-adrenal axis. Varying patterns of responses to stressors are also affected by an animal=s assessment of their prospects for successful coping. Subsequent central and systemic consequences of the stress response include …

Ethological Causes And Consequences Of The Stress Response, Neil Greenberg, James A. Carr, Cliff H. Summers

Faculty Publications and Other Works -- Ecology and Evolutionary Biology

Stress involves real or perceived changes within an organism or in the environment that activate an organism’s attempts to cope by means of evolutionarily ancient neural and endocrine mechanisms. Responses to acute stressors involve catecholamines released in varying proportion at different sites in the sympathetic and central nervous systems. These responses may interact with and be complemented by intrinsic rhythms and responses to chronic or intermittent stressors involving the hypothalamic-pituitary-adrenal axis. Varying patterns of responses to stressors are also affected by an animal=s assessment of their prospects for successful coping. Subsequent central and systemic consequences of the stress response include …