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Quantitative Phenotype Analysis To Identify, Validate And Compare Rat Disease Models, Yiqing Zhao
Quantitative Phenotype Analysis To Identify, Validate And Compare Rat Disease Models, Yiqing Zhao
Theses and Dissertations
Introduction
The laboratory rat has been widely used as an animal model in biomedical research. There are many strains exhibiting a wide variety of phenotypes. Capturing these phenotypes in a centralized database provides researchers with an easy method for choosing the appropriate strains for their studies. Current resources such as NBRP and PhysGen provided some preliminary work in rat phenotype databases. However, there are drawbacks in both projects: (1) small number of animals (6 rats) used by NBRP; (2) NBRP project is a one-time effort for each strain; (3) PhysGen web interface only enables queries within a single study – …