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Fatality After Deliberate Ingestion Of Sustained-Release Ibuprofen: A Case Report, David Wood, Jane Monaghan, Peter Streete, Alison L. Jones, Paul Dargan

Faculty of Science, Medicine and Health - Papers: part A

Introduction Ibuprofen is a nonsteroidal anti-inflammatory drug available over the counter and on prescription for the management of pain and inflammation. Severe toxicity is rare following deliberate self-poisoning with ibuprofen, and patients are usually either asymptomatic or develop only mild gastrointestinal toxicity. Although there have been nine other reported fatalities, co-existent factors have probably contributed to all of these deaths. We report here a fatality from isolated toxicity following self-poisoning with sustained-release ibuprofen. Case report A 26-year-old female presented after deliberate ingestion of up to 105 g sustained-release ibuprofen, with a reduced level of consciousness, severe metabolic acidosis and haemodynamic …