Social and Behavioral Sciences Commons^™

Amyloid Fibril Formation By Bovine Milk Alpha(S2)-Casein Occurs Under Physiological Conditions Yet Is Prevented By Its Natural Counterpart, Alpha(S1)-Casein, David Thorn, Heath Ecroyd, M Sunde, Stephen Poon, John Carver

Heath Ecroyd

The calcified proteinaceous deposits, or corpora amylacea, of bovine mammary tissue often comprise a network of amyloid fibrils, the origins of which have not been fully elucidated. Here, we demonstrate by transmission electron microscopy, dye binding assays, and X-ray fiber diffraction that bovine milk alpha(s2)-casein, a protein synthesized and secreted by mammary epithelial cells, readily forms fibrils in vitro. As a component of whole alpha(s)-casein, alpha(s2)-casein was separated from alpha(s1)-casein under nonreducing conditions via cation-exchange chromatography. Upon incubation at neutral pH and 37 degrees C, the spherical particles typical of alpha(s2)-casein rapidly converted to twisted, ribbon-like fibrils similar to 12 …

Protective Interactions Of Dairy Peptides With Fibril Structures And Relevance To Alzheimer's Disease, Louise Bennett, Williams Roderick, Heath Ecroyd, Yanqin Liu, Sunanda Sudharmarajan, John Carver

Heath Ecroyd

Selected dairy caseins have been shown to have capacity for chaperone-like regulation of folding pathways of other caseins, specifically in preventing development of fibrillar aggregates of beta sheet structure. An assay based on fibril formation by reduced and carboxymethylated-kappa casein (RCM-kCn) was thus used to screen for anti-fibril activity among a selection of dairy protein hydrolysates, in order to discover peptides with possible anti-fibril, chaperone activity. From the selection of eight dairy hydrolysates based on different dairy protein fractions, two of the hydrolysates of whey protein exhibited superior anti-fibril bioactivity against RCM-kCn and amyloid beta (Aβ), the peptide associated with …

Journeys Between Nature And Culture, Diana Wood Conroy, Lesley Head, Jennifer Lamb

Diana Wood Conroy

No abstract provided.

The Reorganization Of A Professional Sports League - A Critical Analysis Of The Restructuring Of The Australian National Basketball League, Winston Wing Hong To, Shayne Quick, Darwin Semotiuk

Winston Wing Hong To

There are numerous examples of professional sports leagues that have failed. Australia has witnessed professor soccer (National Soccer League) and rugby leagues (Super League, Australian Rugby Football League) disappear, be restructured, or reintroduced under a new brand and name (soccer: A-League, rugby league: National Rugby league) (MacDonald & Karg & Lock, 2010; Commonwealth of Australia, 2006). North America has seen the closure of a number of professional sports leagues such as the XFL (American Football), World Hockey Association (Ice Hockey), and the Canadian Soccer League (Football/Soccer) (Bostwick, 2007; Golokhov, nd). There are numerous reasons why these professional sports leagues fail. …

North American Pollinator Partnership Conference: Public Lands Task Force, Tammy Horn

Tammy Horn

No abstract provided.

Local Good Governance Of Rural Infrastructure Development Planning: Case Studies Of Commune Councils In Cambodia, Sophal Ear

Sophal Ear

No abstract provided.

Can Culture Shape The Identity Of A Sport? A Case Study On Lifesaving Sport - Surf Lifesaving Australia And Lifesaving/Sauvetage Canada, Winston Wing Hong To

Winston Wing Hong To

Sport is an important marker of our country's culture and identity. Citizens within a country will cheer and support their sport teams if they are successful, or criticize and judge if they are doing poorly. The importance of culture within sport is an important indicator of a country's success or failure within international competitions; such as the Olympics and World Championships. However, can culture shape the identity of a sport within a country?

Lifesaving is a vital aspect of a country's swim program, as it focuses on reducing injury and death in, on, or around the water. Within Lifesaving, there …

The Utility Of Motivational Interviewing Using Co-Active Life Coaching Skills On Adults Struggling With Obesity: Participants' Perspectives, Courtney Newnham-Kanas, Jennifer Irwin, Don Morrow

Donald Morrow

No abstract provided.

Change-Ing Obesity: A Methodological Account Of A Comprehensive Study For University Students With Obesity, Erin Pearson, Jennifer Irwin, Don Morrow

Donald Morrow

No abstract provided.

Use Of Unnamed Sources Drops From Peaks In 1960s And 1970s, Ann Williams

Ann E Williams

This content analysis of The Washington Post and The New York Times finds that the use of anonymous sources peaked in the 1960s and 1970s. The analysis also finds that contemporary journalists are more likely to explain the reason for anonymity.