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Social and Behavioral Sciences Commons

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2007

Dissertations

Applied Behavior Analysis

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Full-Text Articles in Social and Behavioral Sciences

Behavioral Tolerance Under Variable Ratio Schedules Of Reinforcement, Barry Eshkol Adelman Jun 2007

Behavioral Tolerance Under Variable Ratio Schedules Of Reinforcement, Barry Eshkol Adelman

Dissertations

Previous studies (e.g., Hoffman, Branch, & Sizemore, 1987) have demonstrated that greater drug tolerance develops in responding under fixed-ratio (FR) schedules of reinforcement when the schedule parameter is small than when it is large; little research has been done on related schedules such as variable-ratio (VR). In Experiment 1, three pigeons responded under a multiple FR 5 FR 125 VR 5 VR 125. A range of prechronic doses of cocaine produced dose-dependent reductions in response rates under the component schedules. Following chronic dosing with daily administrations of 5.6 mg/kg, similar dose-response curves were derived by substitutions of the usual dose. In Experiment 2, the procedure was similar but the chronic dose was adjusted to ensure reductions of response rate and reinforcers earned within the range of ...