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2004

Life Sciences

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Articles 1 - 30 of 138

Full-Text Articles in Social and Behavioral Sciences

Intranasal Vaccination With Streptococcal Fibronectin Binding Protein Sfb1 Fails To Prevent Growth And Dissemination Of Streptococcus Pyogenes In A Murine Skin Infection Model, Jason D. Mcarthur, E. Medina, J. Chin, B. J. Currie, K. S. Sriprakash, S. R. Talay, G. S. Chhatwal, Mark J. Walker Dec 2004

Intranasal Vaccination With Streptococcal Fibronectin Binding Protein Sfb1 Fails To Prevent Growth And Dissemination Of Streptococcus Pyogenes In A Murine Skin Infection Model, Jason D. Mcarthur, E. Medina, J. Chin, B. J. Currie, K. S. Sriprakash, S. R. Talay, G. S. Chhatwal, Mark J. Walker

Faculty of Science - Papers (Archive)

Fibronectin binding protein F1 (Sfb1) of Streptococcus pyogenes (group A streptococcus [GAS]) is a well-characterized adhesin that has been shown to induce protection in mice against a lethal intranasal GAS challenge after intranasal immunization with cholera toxin B subunit (CTB) as adjuvant. With a murine skin infection model, we have shown that Sfb1/CTB vaccination neither elicits opsonizing antibodies nor prevents systemic bacterial growth and dissemination to internal organs after a subcutaneous GAS challenge. These results indicate that an Sfb1-based vaccine should be complemented with additional protective antigens in order to be used in areas such as the tropical north of …


Size Matters: A Test Of Boldness In Eight Populations Of The Poeciliid Brachyraphis Episcopi, Culum Brown, Victoria Braithwaite Dec 2004

Size Matters: A Test Of Boldness In Eight Populations Of The Poeciliid Brachyraphis Episcopi, Culum Brown, Victoria Braithwaite

Sentience Collection

Individual variation in behaviour within populations may be explained in part by demographics and long-term, stable individual psychological differences. We examined the relation between boldness (taken as the time to emerge from a shelter and explore a novel environment) and body size in eight populations of the poeciliid Brachyraphis episcopi originating from sites upstream and downstream of waterfalls in four rivers that run into the Panama Canal. The relation between body size and time to emerge from a shelter was positive, with larger fish taking longer to emerge. This relation differed between downstream and upstream sites, being significant in the …


Origin And Evolution Of Large Brains In Toothed Whales, Lori Marino, Daniel W. Mcshea, Mark D. Uhen Dec 2004

Origin And Evolution Of Large Brains In Toothed Whales, Lori Marino, Daniel W. Mcshea, Mark D. Uhen

Veterinary Science and Medicine Collection

Toothed whales (order Cetacea: suborder Odontoceti) are highly encephalized, possessing brains that are significantly larger than expected for their body sizes. In particular, the odontocete superfamily Delphinoidea (dolphins, porpoises, belugas, and narwhals) comprises numerous species with encephalization levels second only to modern humans and greater than all other mammals. Odontocetes have also demonstrated behavioral faculties previously only ascribed to humans and, to some extent, other great apes. How did the large brains of odontocetes evolve? To begin to investigate this question, we quantified and averaged estimates of brain and body size for 36 fossil cetacean species using computed tomography and …


The Other Side Of Silence: Rachel Carson’S Views Of Animals, Marc Bekoff, Jan Nystrom Dec 2004

The Other Side Of Silence: Rachel Carson’S Views Of Animals, Marc Bekoff, Jan Nystrom

Animal Welfare Collection

The publication of Rachel Carson’s Silent Spring in 1962 is widely regarded as one of the major events that launched the modern environmental movement. Silent Spring is a compelling blend of stories, natural history, human values, and biological facts. In this essay we consider Carson’s attitude toward animals in Silent Spring and in other texts. Despite the facts that she was raised to love Nature and animals, little direct attention has been given to Carson’s views about our moral responsibilities to, and the moral standing of animals. Carson favored responsible stewardship, was more of an animal welfarist and environmentalist/conservation biologist …


Agenda: Introduction To The Legal Foundation Of Federal Land Management, University Of Colorado Boulder. Natural Resources Law Center Dec 2004

Agenda: Introduction To The Legal Foundation Of Federal Land Management, University Of Colorado Boulder. Natural Resources Law Center

Introduction to the Legal Foundation of Federal Land Management (December 1-3)

Materials prepared for the course held at the National Center for Atmospheric Research in Boulder, Colorado on December 1-3, 2004

Course instructors: Charles Wilkinson; Sarah Krakoff; Kathryn Mutz; Ann Morgan; Maggie Fox

Contents:

Introduction -- Agenda -- Summaries of laws -- Case studies. Travel management; Oil and gas development; Timber/fuels reduction -- How to influence agency decision makers -- Natural resource related legal and policy resources for the non-legal professional


Introduction To The Legal Foundation Of Federal Land Management, University Of Colorado Boulder. Natural Resources Law Center Dec 2004

Introduction To The Legal Foundation Of Federal Land Management, University Of Colorado Boulder. Natural Resources Law Center

Introduction to the Legal Foundation of Federal Land Management (December 1-3)

1 v. (various pagings) : ill., maps ; 28 cm

Materials prepared for the course held at the National Center for Atmospheric Research in Boulder, Colorado on December 1-3, 2004

Course instructors: Charles Wilkinson; Sarah Krakoff; Kathryn Mutz; Ann Morgan; Maggie Fox

Contents:

Introduction -- Agenda -- Summaries of laws -- Case studies. Travel management; Oil and gas development; Timber/fuels reduction -- How to influence agency decision makers -- Natural resource related legal and policy resources for the non-legal professional


Respiratory Symptoms In Relation To Residential Coal Burning And Environmental Tobacco Smoke Among Early Adolescents In Wuhan, China: A Cross-Sectional Study, C. Anderson Johnson, Jiang Xia, Päivi M. Salo, Yan Li, Grace E. Kissling, Edward L. Avol, Chunhong Liu, Stephanie J. London Dec 2004

Respiratory Symptoms In Relation To Residential Coal Burning And Environmental Tobacco Smoke Among Early Adolescents In Wuhan, China: A Cross-Sectional Study, C. Anderson Johnson, Jiang Xia, Päivi M. Salo, Yan Li, Grace E. Kissling, Edward L. Avol, Chunhong Liu, Stephanie J. London

CGU Faculty Publications and Research

Background

Cigarette smoking and coal burning are the primary sources of indoor air pollution in Chinese households. However, effects of these exposures on Chinese children's respiratory health are not well characterized.

Methods

Seventh grade students (N = 5051) from 22 randomly selected schools in the greater metropolitan area of Wuhan, China, completed an in-class self-administered questionnaire on their respiratory health and home environment.

Results

Coal burning for cooking and/or heating increased odds of wheezing with colds [odds ratio (OR) = 1.57, 95% confidence interval (CI): 1.07–2.29] and without colds (OR = 1.44, 95% CI: 1.05–1.97). For smoking in the home, …


Arkansas Animal Science Department Report 2004, Zelpha B. Johnson, D. Wayne Kellogg Dec 2004

Arkansas Animal Science Department Report 2004, Zelpha B. Johnson, D. Wayne Kellogg

Arkansas Agricultural Experiment Station Research Series

No abstract provided.


Laboratory Routines Cause Animal Stress, Jonathan P. Balcombe, Neal D. Barnard, Chad Sandusky Nov 2004

Laboratory Routines Cause Animal Stress, Jonathan P. Balcombe, Neal D. Barnard, Chad Sandusky

Laboratory Experiments Collection

Eighty published studies were appraised to document the potential stress associated with three routine laboratory procedures commonly performed on animals: handling, blood collection, and orogastric gavage. We defined handling as any non-invasive manipulation occurring as part of routine husbandry, including lifting an animal and cleaning or moving an animal's cage. Significant changes in physiologic parameters correlated with stress (e.g., serum or plasma concentrations of corticosterone, glucose, growth hormone or prolactin, heart rate, blood pressure, and behavior) were associated with all three procedures in multiple species in the studies we examined. The results of these studies demonstrated that animals responded with …


Predators In Natural Fragments: Foraging Ecology Of Wolves In British Columbia’S Central And North Coast Archipelago, C. T. Darimont, M. H. H. Price, N. N. Winchester, J. Gordon-Walker, P. C. Paquet Nov 2004

Predators In Natural Fragments: Foraging Ecology Of Wolves In British Columbia’S Central And North Coast Archipelago, C. T. Darimont, M. H. H. Price, N. N. Winchester, J. Gordon-Walker, P. C. Paquet

Biogeography and Ecological Opportunity Collection

Aim Predator–prey dynamics in fragmented areas may be influenced by spatial features of the landscape. Although little is known about these processes, an increasingly fragmented planet underscores the urgency to predict its consequences. Accordingly, our aim was to examine foraging behaviour of an apex mammalian predator, the wolf (Canis lupus), in an archipelago environment.

Location Mainland and adjacent archipelago of British Columbia, Canada; a largely pristine and naturally fragmented landscape with islands of variable size and isolation.

Methods We sampled 30 mainland watersheds and 29 islands for wolf faeces in summers 2000 and 2001 and identified prey remains. We examined …


Two Distinct Genotypes Of Prtf2, Encoding A Fibronectin Binding Protein, And The Evolution Of The Gene Family In Streptococcus Pyogenes, V. Ramachandran, Jason D. Mcarthur, C. E. Behm, C. Gutzeit, M. Dowton, P. K. Fagan, R. Towers, B. J. Currie, K. S. Sriprakash, Mark J. Walker Nov 2004

Two Distinct Genotypes Of Prtf2, Encoding A Fibronectin Binding Protein, And The Evolution Of The Gene Family In Streptococcus Pyogenes, V. Ramachandran, Jason D. Mcarthur, C. E. Behm, C. Gutzeit, M. Dowton, P. K. Fagan, R. Towers, B. J. Currie, K. S. Sriprakash, Mark J. Walker

Faculty of Science - Papers (Archive)

The group A Streptococcus (GAS) is an important pathogen responsible for a wide range of human diseases. Fibronectin binding proteins (FBPs) play important role in promoting GAS adherence and invasion of host cells. The gene prtF2 encodes a FBP and is contained in approximately 60% of GAS strains. In the present study we have examined 51 prtF2-positive GAS strains isolated from the Northern Territory of Australia and describe two genotypes of prtF2, which are mutually exclusive. Both genotypes have been previously identified in the literature as pfbp and fbaB. We show these genotypes map to the same chromosomal location within …


2004 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library Oct 2004

2004 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti


Event-Related Potential Evidence For Multiple Causes Of The Revelation Effect, P. Andrew Leynes, Joshua Landau, Jessica Walker, Richard J. Addante Oct 2004

Event-Related Potential Evidence For Multiple Causes Of The Revelation Effect, P. Andrew Leynes, Joshua Landau, Jessica Walker, Richard J. Addante

Psychology Faculty Publications

Asking people to discover the identity of a recognition test probe immediately before making a recognition judgment increases the probability of an old judgment. To inform theories of this “revelation effect,” event-related potentials (ERPs) were recorded for revealed and intact test items across two experiments. In Experiment 1, we used a revelation effect paradigm where half of the test probes were presented as anagrams (i.e., a related task) and the other items were presented intact. The pattern of ERP results from this experiment suggested that revealing an item decreases initial familiarity levels and caused the revealed items to elicit similar …


National Program Assessment, Animal Health: 2000-2004, Cyril G. Gay Oct 2004

National Program Assessment, Animal Health: 2000-2004, Cyril G. Gay

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

National Program Assessments are conducted every five-years through the organization of one or more workshop. Workshops allow the Agricultural Research Service (ARS) to periodically update the vision and rationale of each National Program and assess the relevancy, effectiveness, and responsiveness of ARS research. The National Program Staff (NPS) at ARS organizes National Program Workshops to facilitate the review and simultaneously provide an opportunity for customers, stakeholders, and partners to assess the progress made through the National Program and provide input for future modifications to the National Program or the National Program’s research agenda. A workshop for Animal Health has been …


Evolution Of Nociception In Vertebrates: Comparative Analysis Of Lower Vertebrates, Lynne U. Sneddon Oct 2004

Evolution Of Nociception In Vertebrates: Comparative Analysis Of Lower Vertebrates, Lynne U. Sneddon

Veterinary Science and Medicine Collection

Nociception is an important sensory system of major fundamental and clinical relevance. The nociceptive system of higher vertebrates is well studied with a wealth of information about nociceptor properties, involvement of the central nervous system and the in vivo responses to a noxious experience are already characterised. However, relatively little is known about nociception in lower vertebrates and this review brings together a variety of studies to understand how this information can inform the evolution of nociception in vertebrates. It has been demonstrated that teleost fish possess nociceptors innervated by the trigeminal nerve and that these are physiologically similar to …


Semantic Web Technology In Support Of Bioinformatics For Glycan Expression, Amit P. Sheth, William S. York, Christopher Thomas, Meenakshi Nagarajan, John A. Miller, Krzysztof Kochut, Satya S. Sahoo, Xiaochuan Yi Oct 2004

Semantic Web Technology In Support Of Bioinformatics For Glycan Expression, Amit P. Sheth, William S. York, Christopher Thomas, Meenakshi Nagarajan, John A. Miller, Krzysztof Kochut, Satya S. Sahoo, Xiaochuan Yi

Kno.e.sis Publications

Due to the complexity of biological systems, interpretation of data obtained by a single experimental approach can often be interpreted only if viewed from a broader context, taking into account the information obtained by many diverse techniques. The vast amount of interpreted experimental data that is now available via the internet opens the possibility of collecting the relevant pieces of information that will enable scientists to form hypotheses based on the integration of this diverse information. However, the sheer volume of data that is available makes it very difficult to select the information necessary to make a coherent model of …


Lsdis: Large Scale Distributed Information Systems Lab, Amit P. Sheth Oct 2004

Lsdis: Large Scale Distributed Information Systems Lab, Amit P. Sheth

Kno.e.sis Publications

The LSDIS (Large Scale Distributed Information Systems) lab was established in 1994 with the guidance and direction provided by Dr. Amit P. Sheth with the help of Dr. John A. Miller and Dr. Krzysztof J. Kochut. In 1998 this faculty group was further strengthened by the addition of Dr. Ismailcem B. Arpinar. LSDIS is the largest research group in Computer Science at UGA and one of the strongest in its area. During Fall 2004, it is funding 15 students (majority of them PhD), and has one research staff.

Over the years LSDIS has been actively involved in research projects in …


Logic Programs, Iterated Function Systems, And Recurrent Radial Basis Function Networks, Sebastian Bader, Pascal Hitzler Sep 2004

Logic Programs, Iterated Function Systems, And Recurrent Radial Basis Function Networks, Sebastian Bader, Pascal Hitzler

Computer Science and Engineering Faculty Publications

Graphs of the single-step operator for first-order logic programs—displayed in the real plane—exhibit self-similar structures known from topological dynamics, i.e., they appear to be fractals, or more precisely, attractors of iterated function systems. We show that this observation can be made mathematically precise. In particular, we give conditions which ensure that those graphs coincide with attractors of suitably chosen iterated function systems, and conditions which allow the approximation of such graphs by iterated function systems or by fractal interpolation. Since iterated function systems can easily be encoded using recurrent radial basis function networks, we eventually obtain connectionist systems which …


Austrochlamys Heardensis (Fleming, 1957) (Bivalvia: Pectinidae) From Central Kerguelen Plateau, Indian Ocean: Palaeontology And Possible Tectonic Significance, P. G. Quilty, C. V. Murray-Wallace, J. M. Whitehead Sep 2004

Austrochlamys Heardensis (Fleming, 1957) (Bivalvia: Pectinidae) From Central Kerguelen Plateau, Indian Ocean: Palaeontology And Possible Tectonic Significance, P. G. Quilty, C. V. Murray-Wallace, J. M. Whitehead

Faculty of Science - Papers (Archive)

Austrochlamys heardensis (Fleming) is recorded from a boulder of Late Pliocene (3.62–2.5 Ma) volcaniclastic sandstone dredged 70 km east-north-east of Heard Island, the third record of the species. The collection is much larger than the original described by Fleming and includes left valves which are described for the first time. The species is compared with A. anderssoni (Hennig) from Cockburn Island and ‘Chlamys’ mawsoni Fletcher from Îles Kerguelen. The source rock accumulated in fully marine, highly current-affected conditions. The collection is dominated by right valves, possibly because left valves are more susceptible to breakage and the effects of current winnowing. …


Wild Justice And Fair Play: Cooperation, Forgiveness, And Morality In Animals, Marc Bekoff Sep 2004

Wild Justice And Fair Play: Cooperation, Forgiveness, And Morality In Animals, Marc Bekoff

Ethology Collection

In this paper I argue that we can learn much about ‘wild justice’ and the evolutionary origins of social morality – behaving fairly – by studying social play behavior in group-living animals, and that interdisciplinary cooperation will help immensely. In our efforts to learn more about the evolution of morality we need to broaden our comparative research to include animals other than non-human primates. If one is a good Darwinian, it is premature to claim that only humans can be empathic and moral beings. By asking the question ‘What is it like to be another animal?’ we can discover rules …


Inside Unlv, Cate Weeks, Carol C. Harter, Diane Russell, Holly Ivy De Vore Aug 2004

Inside Unlv, Cate Weeks, Carol C. Harter, Diane Russell, Holly Ivy De Vore

Inside UNLV

No abstract provided.


Sexually Dimorphic Effects Of Prenatal Stress On Cognition, Hormonal Responses, And Central Neurotransmitters, Rachel E. Bowman, Neil J. Maclusky, Yessenia Sarmiento, Maya Frankfurt, Marisa Gordon, Victoria N. Luine Aug 2004

Sexually Dimorphic Effects Of Prenatal Stress On Cognition, Hormonal Responses, And Central Neurotransmitters, Rachel E. Bowman, Neil J. Maclusky, Yessenia Sarmiento, Maya Frankfurt, Marisa Gordon, Victoria N. Luine

Psychology Faculty Publications

Exposure to stress during gestation results in physiological and behavioral alterations that persist into adulthood. This study examined the effects of prenatal stress on the postnatal expression of sexually differentiated cognitive, hormonal, and neurochemical profiles in male and female rats. Pregnant dams were subjected to restraint stress three times daily for 45 min during d 14-21 of pregnancy. The offspring of control and prenatally stressed dams were tested for anxiety-related and cognitive behaviors, stress and gonadal steroid hormone levels, as well as monoamines and metabolite levels in selected brain regions. Postnatal testosterone levels (measured at 1 and 5 d) did …


Agribusiness Sheep Updates - 2004 - Part 1, Mark Dolling, Len Stephens, David Thomanson, Norm Adams, Shimim Liu, Peter Buchman, Mike Paton, Dianne Evans, John Edwards, Scott Champion, Alan Langford, A. C. Schlink, J. C. Greeff, M. E. Ladyman, Kimbal M. S. Curtis, John Stanton, Stuart Adams, Neal Fogarty, Matthew Kelly, James Skerritt, Ian Mcfarland Jul 2004

Agribusiness Sheep Updates - 2004 - Part 1, Mark Dolling, Len Stephens, David Thomanson, Norm Adams, Shimim Liu, Peter Buchman, Mike Paton, Dianne Evans, John Edwards, Scott Champion, Alan Langford, A. C. Schlink, J. C. Greeff, M. E. Ladyman, Kimbal M. S. Curtis, John Stanton, Stuart Adams, Neal Fogarty, Matthew Kelly, James Skerritt, Ian Mcfarland

Sheep Updates

Proceedings of the Agribusiness Sheep Updates - 2004 Forward Dr Mark Dolling Manager, Sheep Industries and Pasture, Department of Agriculture Western Australia Keynotes Australian Wool Innovation Limited DR LEN STEPHENS AUSTRALIAN WOOL INNOVATION LIMITED (AWI) Commercialisation of Sheepmeat Eating Quality Outcomes, David Thomason, General Manger Marketing Meat & livestock Australia Limited PLENARY The Fitness of the Future Merino, Norm Adams and Shimin Liu, CSIRO Livestock Industries Ovine Johne’s Disease – Managing the Disease, Managing the Issues, PETER BUCKMAN, CHIEF VETERINARY OFFICER, DEPARTMENT OF AGRICULTURE WESTERN AUSTRALIA Animal Welfare – Changes in Latitudes Changes in Attitudes, Michael Paton and Dianne Evans, …


Enhancing Web Services Description And Discovery To Facilitate Composition, Preeda Rajasekaran, John A. Miller, Kunal Verma, Amit P. Sheth Jul 2004

Enhancing Web Services Description And Discovery To Facilitate Composition, Preeda Rajasekaran, John A. Miller, Kunal Verma, Amit P. Sheth

Kno.e.sis Publications

Web services are in the midst of making the transition from being a promising technology to being widely used in the industry. However, most efforts to use Web services have been manual, thus slowing down the ever changing and dynamic businesses of today. In this paper, we contend that more expressive descriptions of Web services will lead to greater automation and thus provide more agility to businesses. We present the METEOR-S front-end tools for source code annotation and semantic Web service description generation. We also present WSDL-S, a language created for incorporating semantic descriptions in the industry wide accepted WSDL, …


Proposals For Community Discussion - A Quality Future For Recreational Fishing In The South Coast. A Five-Year Strategy For Managing The Recreational Component Of The Catch., South Coast Recreational Fishing Working Group. Jul 2004

Proposals For Community Discussion - A Quality Future For Recreational Fishing In The South Coast. A Five-Year Strategy For Managing The Recreational Component Of The Catch., South Coast Recreational Fishing Working Group.

Fisheries management papers

With a growing population and advances in technology, fishing pressure will continue to grow and anglers will become more efficient at targeting fish, particularly offshore demersal species such as blue groper, dhufish, red snapper, breaksea cod and queen snapper. There is also a clear need for recreational fisheries management to complement the existing management arrangements for the charter industry, and provide the necessary framework for recreational fishing to be incorporated into an integrated management framework with other fishing sectors.


Learning Mixture Models With The Regularized Latent Maximum Entropy Principle, Shaojun Wang, Dale Schuurmans, Fuchun Peng, Yunxin Zhao Jul 2004

Learning Mixture Models With The Regularized Latent Maximum Entropy Principle, Shaojun Wang, Dale Schuurmans, Fuchun Peng, Yunxin Zhao

Kno.e.sis Publications

This paper presents a new approach to estimating mixture models based on a recent inference principle we have proposed: the latent maximum entropy principle (LME). LME is different from Jaynes' maximum entropy principle, standard maximum likelihood, and maximum a posteriori probability estimation. We demonstrate the LME principle by deriving new algorithms for mixture model estimation, and show how robust new variants of the expectation maximization (EM) algorithm can be developed. We show that a regularized version of LME (RLME), is effective at estimating mixture models. It generally yields better results than plain LME, which in turn is often better than …


Australian Backyard Gardens And The Journey Of Migration, Lesley M. Head, Pat Muir, E. Hampel Jul 2004

Australian Backyard Gardens And The Journey Of Migration, Lesley M. Head, Pat Muir, E. Hampel

Faculty of Science - Papers (Archive)

Gardens have been an important site of environmental engagement in Australia since the British colonization. They are places where immigrant people and plants carry on traditions from their homelands, and work out an accommodation with new social and biophysical environments. We examine the backyard gardens of three contemporary migrant groups in suburban Australia, Macedonian, Vietnamese and British-born, and a fourth group of first generation Australians with both parents born overseas. There is strong emphasis on the production of vegetables in Macedonian backyards, and herbs and fruit in Vietnamese backyards. British backyards were more diverse, some focusing on non-native ornamental flowers …


Workflow Management Systems And Erp Systems: Differences, Commonalities, And Applications, Jorge Cardoso, Robert P. Bostrom, Amit P. Sheth Jul 2004

Workflow Management Systems And Erp Systems: Differences, Commonalities, And Applications, Jorge Cardoso, Robert P. Bostrom, Amit P. Sheth

Kno.e.sis Publications

Two important classes of information systems, Workflow Management Systems(WfMSs) and Enterprise Resource Planning (ERP) systems, have been used to support e-business process redesign, integration, and management. While both technologies can help with business process automation, data transfer, and information sharing, the technological approach and features of solutions provided by WfMS and ERP are different. Currently, there is a lack of understanding of these two classes of information systems in the industry and academia, thus hindering their effective applications. In this paper, we present a comprehensive comparison between these two classes of systems. We discuss how the two types of systems …


Discovery Of Web Services In A Federated Registry Environment, Kaarthik Sivashanmugam, Kunal Verma, Amit P. Sheth Jul 2004

Discovery Of Web Services In A Federated Registry Environment, Kaarthik Sivashanmugam, Kunal Verma, Amit P. Sheth

Kno.e.sis Publications

The potential of a large scale growth of private and semi-private registries is creating the need for an infrastructure which can support discovery and publication over a group of autonomous registries. Recent versions of UDDI have made changes to accommodate interactions between distributed registries. In this paper, we discuss METEOR-S Web service Discovery Infrastructure, which provides an ontology-based infrastructure to access a group of registries that are divided based on business domains and grouped into federations. We also discuss how Web service discovery is carried out within a federation.


Animal Model Research: The Apples And Oranges Quandary, Kenneth J. Shapiro Jun 2004

Animal Model Research: The Apples And Oranges Quandary, Kenneth J. Shapiro

Experimentation Collection

In this paper, I explore the premises underlying the problem of the evaluation of animal models. I argue that the presence of similarities and differences between the model and the modelled, although historically and currently a dominant antinomy framing evaluation, is not a bottom-line consideration. What is critical is 1) whether we learn and 2) whether we improve treatment through the animal model research. Similarity between model and modelled and the closely related concept of validity are not coterminus with these critical evaluative measures. In fact, differences between the model and modelled also can provide impetus to new understanding and …