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Dietary Docosahexaenoic Acid And Arachidonic Acid In Early Life: What Is The Best Evidence For Policymakers?, Stewart Forsyth, Philip C. Calder, Francis Zotor, Paul Amuna, Barbara J. Meyer, Bruce Holub

Faculty of Science, Medicine and Health - Papers: part A

Background: A wealth of information on the functional roles of docosahexaenoic acid (DHA) and arachidonic acid (ARA) from cellular, animal, and human studies is available. Yet, there remains a lack of cohesion in policymaking for recommended dietary intakes of DHA and ARA in early life. This is predominantly driven by inconsistent findings from a relatively small number of randomised clinical trials (RCTs), which vary in design, methodology, and outcome measures, all of which were conducted in high-income countries. It is proposed that this selective evidence base may not fully represent the biological importance of DHA and ARA during early and …