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Faculty of Science, Medicine and Health - Papers: part A

2012

Activities

Articles 1 - 4 of 4

Full-Text Articles in Social and Behavioral Sciences

Antioxidant And Anticancer Activities From Aerial Parts Of Acalypha Indica Linn, Duangsuree Sanseera, Wirat Niwatananun, Boonsom Liawruangrath, Saisunee Liawruangrath, Apiwat Baramee, Kongkiat Trisuwan, Stephen G. Pyne Jan 2012

Antioxidant And Anticancer Activities From Aerial Parts Of Acalypha Indica Linn, Duangsuree Sanseera, Wirat Niwatananun, Boonsom Liawruangrath, Saisunee Liawruangrath, Apiwat Baramee, Kongkiat Trisuwan, Stephen G. Pyne

Faculty of Science, Medicine and Health - Papers: part A

Extracts of Acalypha indica Linn. (aerial parts) were investigated for antioxidant activity, anticancer activity, and cytotoxicity. The extracts showed a non-cytotoxic response against Vero cells (African green monkey kidney). The anticancer activity of the extracts was tested using the Resazurin Microplate Assay (REMA). The methanol extract showed anticancer activity against NCIH187-Small Cell Lung Cancer with an IC50 of 25.00 μgmL-1. In addition, the hexane, chloroform, and methanol extracts also showed significant antioxidant activities with an IC50 of 6.19, 5.70, and 7.79 mg/mL, respectively, by means of the DPPH radical scavenging assay. The hexane, chloroform, and methanol extracts also showed significant …


Chemical Composition And Biological Activities Of The Essential Oil From Leaves Of Cleidion Javanicum Bl, Duangsuree Sanseera, Wirat Niwatananun, Boonsom Liawruangrath, Saisunee Liawruangrath, Apiwat Baramee, Stephen G. Pyne Jan 2012

Chemical Composition And Biological Activities Of The Essential Oil From Leaves Of Cleidion Javanicum Bl, Duangsuree Sanseera, Wirat Niwatananun, Boonsom Liawruangrath, Saisunee Liawruangrath, Apiwat Baramee, Stephen G. Pyne

Faculty of Science, Medicine and Health - Papers: part A

The essential oil from the leaves of Cleidion javanicum Bl. was isolated by hydrodistillation with the percentage yield of 0.003 % as a pale yellow liquid. The composition of the essential oil was analysed by means of GC-(FID) and GC-MS. Ten constituents accounting for 92.60% total oil were identified. The major components were ethyl linoleolate (32.12 %), hexadecanoic acid (26.77 %), trans-phytol (24.64 %) and iso-phytol (4.80 %). The antimicrobial, anticancer, antioxidant activities and cytotoxicity test of this essential oil were investigated. The oil showed non-cytotoxic effects against Vero cells (African green monky kidney) because it inhibited more than 50 …


Isolation, Biological Activities, And Synthesis Of The Natural Casuarines, Thunwadee Ritthiwigrom, Stephen G. Pyne Jan 2012

Isolation, Biological Activities, And Synthesis Of The Natural Casuarines, Thunwadee Ritthiwigrom, Stephen G. Pyne

Faculty of Science, Medicine and Health - Papers: part A

This chapter describes the isolation, structure elucidation, glycosidase inhibitory activities, and the synthesis of the four naturally occurring casuarines. These are casuarine, casuarine-6-O-α-d-glucoside, 6-epi-casuarine (uniflorine A), and 3-epi-casuarine.


Chemical Constituents And Antioxidant And Biological Activities Of The Essential Oil From Leaves Of Solanum Spirale, Sukanya Keawsa-Ard, Boonsom Liawruangrath, Saisunee Liawruangrath, Aphiwat Teerawutgulrag, Stephen G. Pyne Jan 2012

Chemical Constituents And Antioxidant And Biological Activities Of The Essential Oil From Leaves Of Solanum Spirale, Sukanya Keawsa-Ard, Boonsom Liawruangrath, Saisunee Liawruangrath, Aphiwat Teerawutgulrag, Stephen G. Pyne

Faculty of Science, Medicine and Health - Papers: part A

The essential oil of the leaves Solanium spirale Roxb. was isolated by hydrodistillation and analyzed for the first time using GC and GC-MS. Thirty-nine constituents were identified, constituting 73.36% of the total chromatographical oil components. (E)-Phytol (48.10%), n-hexadecanoic acid (7.34%), beta-selinene (3.67%), alpha-selinene (2.74%), octadecanoic acid (2.12%) and hexahydrofarnesyl acetone (2.00%) were the major components of this oil. The antioxidant activity of the essential oil was evaluated by using the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. The oil exhibited week antioxidant activity with an IC50 of 41.89 mg/mL. The essential oil showed significant antibacterial activity against both Gram-negative Escherichia coli and …